35.
    发明专利
    未知

    公开(公告)号:DE3834860A1

    公开(公告)日:1990-04-19

    申请号:DE3834860

    申请日:1988-10-13

    Applicant: BASF AG

    Abstract: Heterocyclically substituted alkoxycoumarins of the formula in which R and R are, independently of one another, hydrogen, C1- to C5-alkyl, trifluoromethyl, phenyl, halogen or together are a C3- to C5-alkylene chain; furthermore R is C1- to C5-alkyl or halogen; n is an integer from 0 to 3; R is hydrogen or C1- to C4-alkyl and Het is one of the following heterocycles: with the following meanings for the symbols used: X is oxygen or sulphur; R is optionally C1-C4-alkoxy-substituted C1-C10-alkyl, 5-6-membered oxacycloalkyl, C3-C7-cycloalkyl, benzyl, an optionally halogen- or NO2-substituted phenyl radical, a pyridine ring, C1-C5-alkoxycarbonyl, perfluoro-C1-C2-alkyl; R is C1-C5-alkyl, C1-C5-alkoxy; R is C1-C5-alkyl, an optionally halogen-substituted benzyl radical, halogen; m is 0 to 2; R is C1-C5-alkyl, C3-C6-cycloalkyl, benzyl, phenyl; R is hydrogen, C1-C4-alkyl; R is C1-C5-alkyl, C3-C6-cycloalkyl; R is C1-C5-alkyl; R is hydrogen, C1-C5-alkyl, C3-C6-cycloalkyl; R is C1-C5-alkyl, halogen, p = 0 to 2; R is C1-C5-alkyl, q = 0 or 1; R , R are hydrogen, C1-C5-alkyl, benzyl; R is hydrogen, C1-C5-alkyl; R is C1-C5-alkyl with the proviso that R is not phenyl when X is oxygen, R is methyl and R to R are hydrogen, method for their preparation and medicaments prepared therefrom.

    38.
    发明专利
    未知

    公开(公告)号:DE3243158A1

    公开(公告)日:1984-05-24

    申请号:DE3243158

    申请日:1982-11-23

    Applicant: BASF AG

    Abstract: Sulfonates of hydroxycoumarins of the formula I (I) where R1 and R2 are identical or different and are each hydrogen, halogen or alkyl of 1 to 5 carbon atoms which can be substituted by -NR4R5, -OR4 or -OC(O)R4, where R4 and R5 are identical or different and are each hydrogen or alkyl of 1 to 4 carbon atoms, or R1 and R2 are each a carboxylic acid group -OC(O)R4 or a carboxamido radical, with the proviso that R1 is not methyl when R2 is hydrogen, or R1 and R2 together form a -(CH2)n- chain where n is 3-5, and R3 is a straight-chain or branched alkyl radical of 1 to 8 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, each of which can be substituted by halogen, -OR4, -NR4R5, -CN or phenyl, or R3 is a straight-chain or branched alkenyl radical of 3 to 8 carbon atoms, an amino group - NR4R5, or phenyl or naphthyl, each of which is unsubstituted or monosubstituted or polysubstituted by -OR4, -NR4R5, -NO2, halogen, -SR4, -S(O)R4, -OS(O)R4, -SCF3, -OS(O)CF3, -CN, -C(O)R4, -OC(O)R4, -NHC(O)R4, -CF3, C1-C4-alkyl or a combination of these substituents, a process for their preparation, drugs containing these compounds, and compounds of the formula I, in which R1 is methyl and R2 is hydrogen, for use as drugs.

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