公开(公告)号：DE19635674A1

公开(公告)日：1998-03-05

申请号：DE19635674

申请日：1996-09-03

Applicant: BASF AG

Inventor： SCHAEFER BERND DR ,  ZIERKE THOMAS DR

IPC: C07D213/81 ,  C07B43/00 ,  C07C257/10 ,  C07D213/73 ,  C07D213/78 ,  C07D271/06 ,  C07D401/12 ,  C07D413/12 ,  C07K1/06 ,  C07K5/062 ,  C07D401/06

Abstract: The invention concerns a process for preparing amidines and their salts with inorganic or organic acids. According to this process, the corresponding nitrile is reacted with ammonia, a C1-C6 alkylamine or hydrazine in the presence of a mercapto carboxylic acid and optionally in the presence of an inorganic or organic ammonium salt.

公开(公告)号：CZ153797A3

公开(公告)日：1998-02-18

申请号：CZ153797

申请日：1995-11-25

Applicant: BASF AG

Inventor： BOHM HANS JOACHIM DR ,  KOSER STEFAN DR ,  MACK HELMUT DR ,  PFEIFFER THOMAS DR ,  SEITZ WERNER DR ,  HOFFKEN HANS WOLFGANG DR ,  HORNBERGER WILFRIED DR ,  ZIERKE THOMAS DR

IPC: A61K38/00 ,  A61K38/05 ,  A61K38/55 ,  A61P7/02 ,  C07K5/06 ,  C07K5/062 ,  C07K5/065 ,  C07K5/072 ,  C07K5/087

公开(公告)号：DE19630082A1

公开(公告)日：1998-01-29

申请号：DE19630082

申请日：1996-07-26

Applicant: BASF AG

Inventor： MACK HELMUT DR ,  PFEIFFER THOMAS DR ,  SEITZ WERNER DR ,  ZIERKE THOMAS DR ,  BALKENHOHL FRIEDHELM DR ,  LANGE UDO DR

IPC: C12P17/04 ,  C07D207/22 ,  C07D401/12 ,  C07D401/04 ,  C07B57/00

Abstract: A process is disclosed for preparing 3-pyrroline-2-carboxylic acid derivatives of formula (I), in which R stands for H, C1-C6-alkyl, benzyl, benzyl substituted at the phenyl radical, allyloxycarbonyl, C1-C6-alkyloxycarbonyl, benzyloxycarbonyl, in which the benzyl radical can be substituted by OCH3 radicals, or for C1-C4-alkylcarbonyl; or R stands for an amino acid radical which can be alkylated or acylated at the nitrogen and is linked by the C-terminal; and R stands for OH, C1-C4-alkyloxy, benzyloxy or an N R group, in which R and R represent independently from each other H, C1-C4-alkyl, benzyl, phenyl or pyridyl, in which the aromatic compounds in R and R can be substituted by up to three identical or different substituents selected from the group composed of methyl, methoxy, hydroxy, cyano or halogen. According to this process, the sulphonic acid radical is eliminated by means of a base from a compound having the formula (II), in which R and R have the above meanings and R stands for C1-C6-alkyl, benzyl, trifluoromethyl, naphthyl or phenyl optionally substituted by radicals from the group composed of methyl, nitro and halogen.

公开(公告)号：ES2078279T3

公开(公告)日：1995-12-16

申请号：ES90116033

申请日：1990-08-22

Applicant: BASF AG

Inventor： KOBER REINER DR ,  SEELE RAINER DR ,  ZIERKE THOMAS DR ,  ISAK HEINZ DR ,  KARBACH STEFAN DR ,  WEGNER GUNTER DR

IPC: C07B49/00 ,  C07F3/02 ,  C07F7/08

Abstract: Preparation of ether solutions of arylmethylmagnesium halides… Ar-CH2-Mg-Hal I… (Aryl = unsubstituted or substituted aryl; Hal = Cl, Br) by the Grignard process from arylmethyl halides II… Ar-CH2-Hal II… with magnesium in an ether as a solvent, by using III… tert-butyl-O-R III… (R = C1-C3-alkyl) for this purpose.

公开(公告)号：DE59203929D1

公开(公告)日：1995-11-16

申请号：DE59203929

申请日：1992-02-21

Applicant: BASF AG

Inventor： KIRCHNER JUERGEN ,  SCHMIDT OSKAR DR ,  GROSSMANN KLAUS DR ,  RADEMACHER WILHELM DR ,  HEPP MICHAEL DR ,  ZIERKE THOMAS DR

IPC: A01N37/50 ,  A01N37/36

公开(公告)号：DE4415998A1

公开(公告)日：1995-11-09

申请号：DE4415998

申请日：1994-05-06

Applicant: BASF AG

Inventor： AMBERG WILHELM DR ,  BERNARD HARALD DR ,  BUSCHMANN ERNST DR ,  HAUPT ANDREAS DR ,  JANITSCHKE LOTHAR DR ,  JANSSEN BERND DR ,  KARL ULRICH DR ,  KLING ANDREAS DR ,  MUELLER STEFAN DR ,  POTZOLLI BERND DE DR ,  RITTER KURT DR ,  ZIERKE THOMAS DR ,  THYES MARCO DR

IPC: A61K38/00 ,  A61P35/00 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06

Abstract: Compounds of formula (I) are disclosed, wherein R , R , R , and R have the meanings indicated in the description, as well as a process for the production of these compounds. The compounds are suitable for use as starting material for the synthesis of substances which have anti-tumour properties.

公开(公告)号：DE4415997A1

公开(公告)日：1995-11-09

申请号：DE4415997

申请日：1994-05-06

Applicant: BASF AG

Inventor： AMBERG WILHELM DR ,  BERNARD HARALD DR ,  BUSCHMANN ERNST DR ,  HAUPT ANDREAS DR ,  JANITSCHKE LOTHAR DR ,  JANSSEN BERND DR ,  KARL ULRICH DR ,  KLING ANDREAS DR ,  MUELLER STEFAN DR ,  POTZOLLI BERND DE DR ,  RITTER KURT DR ,  ZIERKE THOMAS DR ,  THYES MARCO DR

IPC: A61K38/00 ,  A61K38/08 ,  A61P35/00 ,  C07K1/08 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06 ,  C07K14/52

Abstract: Disclosed is the compound Me2Val-Val-MeVal-Pro-Pro-NHBzl. HCl. The compound is produced from Z-Val-Val-MeVal-Pro-OR , wherein Z and R have the meanings indicated in the description. The compound disclosed has anti-neoplastic properties.

公开(公告)号：CZ279477B6

公开(公告)日：1995-05-17

申请号：CS472890

申请日：1990-09-28

Applicant: BASF AG

Inventor： SAUTER HUBERT DR ,  ZIERKE THOMAS DR ,  REUTHER WOLFGANG DR ,  BAUS ULF DR ,  LORENZ GISELA DR ,  AMMERMANN EBERHARD DR

IPC: A01N43/653 ,  C07D249/08 ,  C07D401/12 ,  C07D403/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D521/00

Abstract: Compounds of the formula I I where Ar is unsubstituted or substituted phenyl, pyridyl, thienyl or napthyl, R1 is hydrogen or CN, R2 is unsubstituted or substituted aryl, hetaryl, alkyl or cycloalkyl, or is unsubstituted or substituted alkenyl or alkynyl, x is CH2, O or S and n is 0 or 1, their plant-tolerated acid addition salts and metal complexes, and fungicides and growth regulators containing these compounds.

公开(公告)号：ES2062576T3

公开(公告)日：1994-12-16

申请号：ES91101013

申请日：1991-01-26

Applicant: BASF AG

Inventor： ZIPPERER BERNHARD DR ,  LAUER MANFRED DR ,  GOETZ NORBERT DR ,  ZIERKE THOMAS DR ,  AMMERMANN EBERHARD DR ,  LORENZ GISELA DR

IPC: A01N43/40 ,  A01N43/54 ,  A01N43/58 ,  A01N43/60 ,  C07D213/30 ,  C07D213/50 ,  C07D401/06 ,  C07D405/06 ,  C07D407/06 ,  C07D409/06

Abstract: Heteroarylalkenes of the general formula I … …… … (Ar = heteroaryl, … A = C1-C6-alkyl, C2-C6-alkenyl, C3-C8-cycloalkyl, (C3-C8)-cycloalkyl-(C1-C3)-alkyl, mono-, di- or tricyclic substituted or unsubstituted aryl or aralkyl; … Z = … … where …… R = hydrogen, C2-C4-acyl, optionally substituted benzoyl, C1-C4-alkylsulphonyl, phenylsulphonyl which is unsubstituted or substituted by C1-C4-alkyl, or the radical R , … R is C1-C4-alkyl, substituted or unsubstituted phenyl or benzyl and … Hal is fluorine, chlorine, bromine or iodine; …… B is substituted or unsubstituted mono- or dicyclic aryl, aralkyl or heteroaryl) … and their N-oxides and acid addition salts; furthermore the preparation of these substances, intermediates therefor and their preparation, heteroarylalkene-containing fungicidal agents, and a suitable method for controlling fungal pests.

公开(公告)号：DE59101901D1

公开(公告)日：1994-07-21

申请号：DE59101901

申请日：1991-02-04

Applicant: BASF AG

Inventor： ZIERKE THOMAS DR ,  KUEKENHOEHNER THOMAS DR ,  AMMERMANN EBERHARD DR ,  LORENZ GISELA DR

IPC: A01N43/40 ,  C07D213/30 ,  C07D213/42 ,  C07D213/57 ,  C07D213/89

Abstract: Compounds of the formula 1 1 where R is unsubstituted or substituted cycloalkyl or cycloalkenyl, X, Y and Z are hydrogen, halogen, alkyl, alkoxy, alkoximino, haloalkyl, cyano, nitro or unsubstituted or substituted phenyl or phenoxy, W is -CH2- or -CH2CH2- and n is 0 or 1, and the plant-tolerated acid-addition salts thereof, and fungicides containing these compounds are described.