公开(公告)号：CA2311308A1

公开(公告)日：1999-06-10

申请号：CA2311308

申请日：1998-11-30

Applicant: BASF AG

Inventor： ERNST ANDREAS ,  MEFFERT HELMUT ,  SANNER AXEL ,  KOTHRADE STEPHAN ,  BERNDL GUNTHER

IPC: A61K47/32 ,  A23K20/10 ,  A23K40/10 ,  A23K40/20 ,  A23L27/00 ,  A23L33/10 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K31/277 ,  A61K31/421 ,  A61K47/30

Abstract: The invention relates to a method for producing solid dosing forms by mixing at least one polymeric binding agent, at least one active substance, and optional common additives while producing a plastic mixture and during shaping, whereby a copolymer from a N-vinyl lactam and from an copolymerizable monomer with a hydrophobic radical is used as a polymeric binding agent. Dosing forms which slowly release the active substance are obtained in a simple and economical manner.

公开(公告)号：AU3542097A

公开(公告)日：1998-02-10

申请号：AU3542097

申请日：1997-07-07

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/16 ,  A61K9/20 ,  A61K36/00 ,  A61K36/16 ,  A61K36/38 ,  A61K36/48 ,  A61K36/61 ,  A61K35/78 ,  A61K9/14

公开(公告)号：CA2408915C

公开(公告)日：2010-07-27

申请号：CA2408915

申请日：2001-05-29

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  BREITENBACH JORG ,  HEGER ROBERT ,  STADLER MICHAEL ,  WILKE PETER ,  ROSENBERG JORG

IPC: A61F13/53 ,  A61K9/107 ,  A23P1/02 ,  A23P1/08 ,  A61F13/49 ,  A61K9/16 ,  A61K47/00 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/26 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38

Abstract: The invention relates to self-emulsifying formulations based on an active substance constituent and on a formulation base with a lipid constituent and with a binding agent constituent. The invention also relates to the use of this formulation as a dosed form in the area of life science. The invention also relates to a method for producing self-emulsifying formulations by mixing the formulation constituents while forming a plastic mixture and optionally while preparing the formulations as a dosed form, advantageously while using melt extrusion. The formulations spontaneously form emulsions in water or in aqueous fluids.

公开(公告)号：CA2298659C

公开(公告)日：2007-09-11

申请号：CA2298659

申请日：1998-07-21

Applicant: BASF AG

Inventor： NEUMANN JORG ,  LIEPOLD BERND ,  VOLLGRAF CHRISTIANE ,  ROSENBERG JORG ,  ZEIDLER JURGEN ,  BREITENBACH JORG ,  BERNDL GUNTHER

IPC: A61K31/192 ,  A61J3/00 ,  A61K9/20 ,  A61K47/02 ,  A61K47/22 ,  A61K47/32 ,  A61P29/00

Abstract: The invention relates to a fast acting analgesic, containing ibuprofen as th e active analgesic substance in an auxiliary substance matrix, with a porous structure and a density of greater than 1 - 2.5 g/cm3.

公开(公告)号：DE50111376D1

公开(公告)日：2006-12-14

申请号：DE50111376

申请日：2001-05-29

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  BREITENBACH JOERG ,  HEGER ROBERT ,  STADLER MICHAEL ,  WILKE PETER ,  ROSENBERG JOERG

IPC: A61F13/53 ,  A61K9/107 ,  A23P1/02 ,  A23P1/08 ,  A61F13/49 ,  A61K9/16 ,  A61K47/00 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/26 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38

Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.

公开(公告)号：BR0012735A

公开(公告)日：2005-02-22

申请号：BR0012735

申请日：2000-04-11

Applicant: BASF AG

Inventor： HEGER ROBERT ,  SCHROF WOLFGANG ,  RIEGER JEANS ,  VOELKEL RUEDIGER ,  BREITTENBACH JOERG ,  ZEIDLER JUERGEN ,  LIEPOLD BERND ,  BERNDL GUNTHER ,  BINDER RUDOLF

IPC: A61K47/22 ,  A61K9/16 ,  A61K31/4184 ,  A61K31/4439 ,  A61K45/00 ,  A61K47/34 ,  A61K47/42 ,  A61P1/00 ,  A61P1/04 ,  A61P35/00

公开(公告)号：DE50005082D1

公开(公告)日：2004-02-26

申请号：DE50005082

申请日：2000-03-17

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  BREITENBACH JOERG ,  RUCHATZ FOLKER ,  SANNER AXEL ,  SACK HEINRICH

IPC: A61K47/14 ,  A61K9/20 ,  A61K47/32

Abstract: The invention relates to excipients in powder form for use in solid pharmaceutical presentations, comprising a pharmaceutically acceptable polymer and a liquid or semisolid solubilizing surface-active substance.

公开(公告)号：AT258045T

公开(公告)日：2004-02-15

申请号：AT00914148

申请日：2000-03-17

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  BREITENBACH JOERG ,  RUCHATZ FOLKER ,  SANNER AXEL ,  SACK HEINRICH

IPC: A61K47/14 ,  A61K9/20 ,  A61K47/32

Abstract: The invention relates to excipients in powder form for use in solid pharmaceutical presentations, comprising a pharmaceutically acceptable polymer and a liquid or semisolid solubilizing surface-active substance.

公开(公告)号：ES2187457T3

公开(公告)日：2003-06-16

申请号：ES00916925

申请日：2000-03-10

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  REINHOLD ULRICH ,  SIMON DIRK ,  LEHMANN STEPHAN

IPC: A01N25/08 ,  A01N25/10 ,  A61K8/73 ,  A61K8/86 ,  A61K9/20 ,  A61K9/22 ,  A61K31/192 ,  A61K31/565 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/40 ,  A61K47/48 ,  A61Q19/00

公开(公告)号：DE59904879D1

公开(公告)日：2003-05-08

申请号：DE59904879

申请日：1999-11-30

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  KOTHRADE STEPHAN ,  KESSLER THOMAS ,  LANGE ARMIN ,  HOFMANN JUERGEN ,  REINHOLD ULRICH

IPC: A61J3/10 ,  A61K9/16 ,  A61K9/20 ,  B29C47/42