公开(公告)号：DE102005027039A1

公开(公告)日：2006-12-21

申请号：DE102005027039

申请日：2005-06-10

Applicant: BASF AG

Inventor： EXNER CHRISTIAN ,  BAUS ULF ,  HOLOCH JAN ,  BOLLSCHWEILER CLAUS ,  SUBKOWSKI THOMAS ,  KAROS MARVIN ,  LEMAIRE HANS-GEORG

IPC: C08J9/224 ,  C08J7/04 ,  C09D189/00

Abstract: Expandable or expanded, thermoplastic polymer particles with a coating comprising hydrophobin, in particular proteins of the general structural formula (I) Xn-C1-X1-50-C2-X0-5-C3-X1-100-C4-X1-100-C5-X1-50-C6-X0-5-C7-X1-50-C8-Xm (I) where X is any of the 20 naturally occurring amino acids, n and m are numbers between 0 and 500, C is cysteine, and their use as antistatics.

公开(公告)号：CA2602155A1

公开(公告)日：2006-10-05

申请号：CA2602155

申请日：2006-03-27

Applicant: BASF AG

Inventor： BECKER HEIKE ,  SUBKOWSKI THOMAS ,  BOLLSCHWEILER CLAUS ,  LEMAIRE HANS-GEORG ,  BAUS ULF ,  KAROS MARVIN

IPC: C11D3/38

Abstract: Use of hydrophobins for soil-repellent treatment of hard surfaces, in particular in combination with a cleansing of the surface, processes for soil-repellent treatment of hard surfaces, cleansing agents for hard surfaces and also hard surfaces with a soil-repellent coating comprising hydrophobins.

公开(公告)号：CA2599985A1

公开(公告)日：2006-10-05

申请号：CA2599985

申请日：2006-03-29

Applicant: BASF AG

Inventor： KORMANN CLAUDIUS ,  KIEFER MATTHIAS ,  KAROS MARVIN ,  LEMAIRE HANS-GEORG ,  BAUS ULF ,  SUBKOWSKI THOMAS ,  POSSELT DIETMAR ,  BOLLSCHWEILER CLAUS ,  GUZMANN MARCUS ,  SCHMITT WERNER

IPC: B01D17/04 ,  B01D17/05 ,  C07K14/375 ,  C10G33/04 ,  C10L1/22 ,  C10L1/24 ,  C10L1/26

Abstract: The present invention relates to the use of at least one protein, in particular at least one hydrophobin or at least one derivative thereof, for improving phase separation in compositions comprising at least two liquid phases, to methods for separating at least two liquid phases in a composition comprising at least two liquid phases, and to formulations comprising at least one compound selected from the group consisting of fuels, combustibles, crude oils or water-soluble or oil-soluble polymer solutions and at least one protein, in particular at least one hydrophobin or derivatives thereof.

公开(公告)号：DE10319240A1

公开(公告)日：2004-11-18

申请号：DE10319240

申请日：2003-04-28

Applicant: BASF AG

Inventor： LEMAIRE HANS-GEORG ,  TAEGER TILMAN LUEDECKE ,  PABST GUNTHER ,  LAMALLE PHILIPPE ,  BREUER MICHAEL ,  KROEGER BURKHARD ,  SUBKOWSKI THOMAS

IPC: C14C1/06

Abstract: Removal of keratin from animal skins involves treatment in an aqueous liquor containing, with respect to salted weight, 0.05-5 %, by weight mercaptan(s) (I) or the corresponding alkali(ne earth) metal, ammonium or phosphonium salt(s) and also compound(s) catalyzing hydrolysis of peptide bonds. Removal of keratin from animal skins involves treatment in an aqueous liquor containing, with respect to salted weight, 0.05-5 %, by weight mercaptan(s) of formula (I) or the corresponding alkali(ne earth) metal, ammonium or phosphonium salt(s) and also compound(s) catalyzing hydrolysis of peptide bonds: [Image] R1>H or 1-12 C alkyl, optionally with 1 or more S-H or O-H groups; X1>->4>S-H in at least one case, otherwise H, 1-4 C alkyl, O-H or NHR2>; and R2>H, 1-12 C alkyl or 1-4 C alkyl-C=O. If R1> contains no O-H or S-H, at least one other X1>->4> is S-H, OH or NHR2>. Independent claims are also included for: (1) unhaired hides produced by this process; (2) residual liquor from the process, containing melanine or its degradation products; (3) working up this residual liquor by optionally separating lime, then neutralizing with acid and separating proteins.

公开(公告)号：BG105018A

公开(公告)日：2001-12-31

申请号：BG10501800

申请日：2000-12-04

Applicant: BASF AG

Inventor： KOCK MICHAEL ,  HOEGER THOMAS ,  KROEGER BURKHARD ,  OTTERBACH BERND ,  LUBISCH WILFRIED ,  LEMAIRE HANS-GEORG

IPC: A01K67/027 ,  A61K38/00 ,  A61K38/45 ,  A61K48/00 ,  A61K49/00 ,  A61P43/00 ,  C07K14/455 ,  C12N1/15 ,  C12N1/19 ,  C12N5/10 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12Q1/68 ,  G01N33/53 ,  A61K31/00

Abstract: The invention relates to poly(ADP-ribose)polymerase (PARP) homologues which are characterised by an amino acid sequence with a) a functional NAD+-binding site, and b) no zinc-finger-sequence motif of general formula CX2CHmHX2C, wherein m is an integral number of 28 or 30 and the radicals X represent any amino acid, independently of each other; and to the functional equivalents of said poly(ADP-ribose)polymerase (PARP) homologues. The invention also relates to nucleic acid coding the poly(ADP-ribose)polymerase (PARP) homologues, to antibodies with specificity for the novel protein, to pharmaceutical and gene therapy agents containing the inventive products, to methods for analytically determining the inventive proteins and nucleic acids, to methods for identifying the effectors or bonding partners of the inventive proteins, to novel PARP effectors and to methods for determining the effectiveness of effectors of this type. 32 claims

公开(公告)号：CA2330206A1

公开(公告)日：1999-12-16

申请号：CA2330206

申请日：1999-06-04

Applicant: BASF AG

Inventor： HOGER THOMAS ,  KOCK MICHAEL ,  KROGER BURKHARD ,  OTTERBACH BERND ,  LUBISCH WILFRIED ,  LEMAIRE HANS-GEORG

IPC: A01K67/027 ,  A61K38/00 ,  A61K38/45 ,  A61K48/00 ,  A61K49/00 ,  A61P43/00 ,  C07K14/455 ,  C12N1/15 ,  C12N1/19 ,  C12N5/10 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12Q1/68 ,  G01N33/53 ,  C12N15/10 ,  A61K31/70

Abstract: The invention relates to poly(ADP-ribose)polymerase (PARP) homologues which are characterised by an amino acid sequence with a) a functional NAD+-binding site and b) no zinc-finger-sequence motif of general formula CX2CXmHX2C, wherein m is an integral number 28 or 30 and the radicals X represent any amino acid, independently of each other; and to the functional equivalents of said poly(ADP-ribose)polymerase (PARP) homologues. The invention also relates to nucleic acids coding the poly(ADP-ribose)polymerase (PARP) homologues, to antibodies with specificity for the novel protein, to pharmaceutical and gene therapy agents containing the inventive products, to methods for analytically determining the inventive proteins and nucleic acids, to methods for identifying the effectors or bonding partners of the inventive proteins, to novel PARP effectors and to methods for determining the effectiveness of effectors of this type.

公开(公告)号：CA2186788A1

公开(公告)日：1995-10-05

申请号：CA2186788

申请日：1995-03-20

Applicant: BASF AG

Inventor： ULTSCH ANDREAS ,  STERRER SYLVIA ,  BACH ALFRED ,  LEMAIRE HANS-GEORG ,  HOEGER THOMAS

IPC: G01N33/566 ,  C07K14/705 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12P21/02 ,  C12R1/91

Abstract: The invention concerns a method for the preparation of eucaryotic cell lines for the permanently ectopic expression of glutamate receptors, the cell lines being prepared by the transformation of cells containing nucleic acids coding for glutamate receptors. The method is characterized in that, during the establishment of the cell lines, at least one of the following conditions is satisfied for the culture: a) the transformed cells are cultured in a culture medium containing a glutamate precursor; b) the transformed cells are cultured in the presence of a glutamate-receptor antagonist: c) the transformed cells ant cultured in a first phase under conditions in which glutamate-receptor expression is repressed and in a second phase under conditions in which the repression is discontinued. The invention also concerns the cell lines thus obtained and their use.

公开(公告)号：DE59007517D1

公开(公告)日：1994-11-24

申请号：DE59007517

申请日：1990-05-04

Applicant: BASF AG

Inventor： LEMAIRE HANS-GEORG ,  HILLEN HEINZ ,  MOELLER ACHIM ,  DAUM LOTHAR ,  DOERPER THOMAS ,  SUBKOWSKI THOMAS

IPC: A61K35/22 ,  A61K38/00 ,  A61K38/17 ,  A61K38/19 ,  A61P7/00 ,  A61P7/02 ,  A61P7/04 ,  A61P11/00 ,  A61P19/00 ,  A61P19/02 ,  A61P19/08 ,  A61P25/00 ,  A61P29/00 ,  A61P31/04 ,  A61P37/00 ,  A61P37/02 ,  A61P37/08 ,  A61P43/00 ,  C07K1/18 ,  C07K1/22 ,  C07K7/08 ,  C07K14/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/525 ,  C07K14/715 ,  C07K16/18 ,  C07K15/14 ,  A61K35/12

Abstract: PCT No. PCT/EP90/00719 Sec. 371 Date Sep. 26, 1991 Sec. 102(e) Date Sep. 26, 1991 PCT Filed May 4, 1990 PCT Pub. No. WO90/13575 PCT Pub. Date Nov. 15, 1990.Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Set Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.

公开(公告)号：CA2050300A1

公开(公告)日：1990-11-10

申请号：CA2050300

申请日：1990-05-04

Applicant: BASF AG

Inventor： HILLEN HEINZ ,  MOELLER ACHIM ,  DOERPER THOMAS ,  DAUM LOTHAR ,  LEMAIRE HANS-GEORG ,  SUBKOWSKI THOMAS

IPC: A61K35/22 ,  A61K38/00 ,  A61K38/17 ,  A61K38/19 ,  A61P7/00 ,  A61P7/02 ,  A61P7/04 ,  A61P11/00 ,  A61P19/00 ,  A61P19/02 ,  A61P19/08 ,  A61P25/00 ,  A61P29/00 ,  A61P31/04 ,  A61P37/00 ,  A61P37/02 ,  A61P37/08 ,  A61P43/00 ,  C07K1/18 ,  C07K1/22 ,  C07K7/08 ,  C07K14/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/525 ,  C07K14/715 ,  C07K16/18

Abstract: Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Ser Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.

公开(公告)号：BRPI0611240A2

公开(公告)日：2016-11-16

申请号：BRPI0611240

申请日：2006-05-31

Applicant: BASF AG

Inventor： MENDERA CHRISTINE ,  BOLLSCHWEILER CLAUS ,  LEMAIRE HANS-GEORG ,  KAROS MARVIN ,  BAUR RICHARD ,  SUBKOWSKI THOMAS ,  MONTAG THORSTEN ,  BAUS ULF ,  SCHWENDEMANN VOLKER

IPC: D06M15/15