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公开(公告)号：AT455546T
公开(公告)日：2010-02-15
申请号：AT04780381
申请日：2004-08-06
Applicant: VERTEX PHARMA , LEDEBOER MARK W , DAVIES ROBERT J
Inventor： ARNOST MICHAEL J , BEMIS GUY W , DAVIES ROBERT J , FORSTER CORNELIA J , GREY RONALD , LEDFORD BRIAN , MARHEFKA CRAIG , MESSERSMITH DAVID , PIERCE ALBERT C , SALITURO FRANCESCO , WANG JIAN , LEDEBOER MARK W
IPC: A61K31/4196 , A61P35/00 , C07D249/14 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D417/04
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公开(公告)号：MX2008012860A
公开(公告)日：2009-01-07
申请号：MX2008012860
申请日：2007-04-05
Applicant: VERTEX PHARMA
Inventor： FARMER LUC , CAO JINGRONG , MALTAIS FRANCOIS , FORSTER CORNELIA , PIERCE ALBERT , WANNAMAKER MARION , GAO HUAI , LEDEBOER MARK , SALITURO FRANCESCO , MESSERSMITH DAVID , WANG TIANSHENG , DUFFY JOHN , MARTINEZ-BOTELLA GABRIEL , MARONE VALERIE
IPC: C07D487/04
Abstract: La presente invención se refiere a compuestos útiles como inhibidores de las proteína cinasas, en particular de las cinasas de la familia JAK. La invención también provee composiciones farmacéuticamente aceptables que comprenden los compuestos y métodos de uso de las composiciones en el tratamiento de diversas enfermedades, estados patológicos o trastornos.
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公开(公告)号：HK1116349A1
公开(公告)日：2008-12-19
申请号：HK08106688
申请日：2008-06-18
Applicant: VERTEX PHARMA
Inventor： LEDEBOER MARK W , PIERCE ALBERT C , BEMIS GUY W , FARMER LUC J , WANG TIANSHENG , MESSERSMITH DAVID , DUFFY JOHN P , WANG JIAN , SALITURO FRANCESCO G
IPC: C07D20060101 , A61K20060101 , A61P20060101
Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
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Patent Agency Ranking
公开(公告)号：CA2596830A1
公开(公告)日：2006-09-14
申请号：CA2596830
申请日：2006-02-02
Applicant: VERTEX PHARMA
Inventor： MESSERSMITH DAVID , DUFFY JOHN P , WANG JIAN , SALITURO FRANCESCO G , LEDEBOER MARK W , FARMER LUC J , WANG TIANSHENG , BEMIS GUY W , PIERCE ALBERT C
IPC: C07D487/04 , A61K31/519 , A61P7/00 , A61P11/00 , A61P19/00 , A61P37/00
Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
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公开(公告)号：NO20052888A
公开(公告)日：2005-08-12
申请号：NO20052888
申请日：2005-06-10
Applicant: VERTEX PHARMA
Inventor： ARNOST MICHAEL J , FORSTER CORNELIA J , DAVIES ROBERT J , PIERCE ALBERT , BINCH HAYLEY , LEDEBOER MARK , LEDFORD BRIAN E , GALULLO VINCENT , GREY RONALD , TIAN SHI-KAI , XU JINWANG , MESSERSMITH DAVID , NANTHAKUMAR SUGHANTHI , JAYARAJ ANDREW
IPC: A61K31/4196 , A61K31/5377 , A61K31/541 , A61K31/55 , C07D249/10 , C07D249/14 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D413/02 , C07D417/02 , C07D417/04 , C07D417/12 , C07D417/14 , C07D471/14 , C07D487/04 , C07D495/04 , A61K31/41 , A61P3/00 , A61P9/00 , A61P19/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/00 , C07D498/04 , C07D513/04
CPC classification number: C07D401/04 , C07D249/10 , C07D249/14 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D471/14 , C07D487/04 , C07D495/04
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公开(公告)号：UY28460A1
公开(公告)日：2005-02-28
申请号：UY28460
申请日：2004-08-06
Applicant: VERTEX PHARMA
Inventor： WANG JIAN , ARNOST MICHAEL J , BEMIS GUY W , DAVIES ROBERT J , JR RONALD GREY , FORSTER CORNELIA J , LEDEBOER MARK W , LEDFORD BRIAN , MARHEFKA CRAIG , MESSERSMITH DAVID , PIERCE ALBERT C , SALITURO FRANCESCO G
IPC: C12N9/00
Abstract: La presente invención se relaciona con los inhibidores de quinasas proteínicas. La invención proporciona además composiciones farmacéuticas que comprenden compuestos de la invención, procesos para la preparación de compuestos y métodos para utilizar las composiciones en el tratamiento de diversos desórdenes.
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公开(公告)号：AU2004263148A1
公开(公告)日：2005-02-17
申请号：AU2004263148
申请日：2004-08-06
Applicant: VERTEX PHARMA , MARK LEDEBOER , DAVIES ROBERT
Inventor： DAVIES ROBERT J , LEDFORD BRIAN , PIERCE ALBERT C , BEMIS GUY W , SALITURO FRANCESCO , MESSERSMITH DAVID , ARNOST MICHAEL J , GREY RONALD JR , MARHEFKA CRAIG , WANG JIAN , FORSTER CORNELIA J
IPC: A61K31/4196 , A61P35/00 , C07D249/14 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D407/12 , C07D409/04 , C07D413/14 , C07D417/04
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公开(公告)号：CA2505789A1
公开(公告)日：2004-06-03
申请号：CA2505789
申请日：2003-11-17
Applicant: VERTEX PHARMA
Inventor： ARNOST MICHAEL , PIERCE ALBERT C , GALULLO VINCENT , FORSTER CORNELIA J , LEDFORD BRIAN , LEDEBOER MARK , TIAN SHI-KAI , MESSERSMITH DAVID , BINCH HAYLEY , XU JINWANG , NANTHAKUMAR SUGANTHI , GREY RONALD , JAYARAJ ANDREW , DAVIES ROBERT J , WANG JIAN , HENKEL GREG , SALITURO FRANCESCO G
IPC: A61K31/4196 , A61K31/5377 , A61K31/541 , A61K31/55 , C07D249/10 , C07D249/14 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D413/02 , C07D417/02 , C07D417/04 , C07D417/12 , C07D417/14 , C07D471/14 , C07D487/04 , C07D495/04 , A61K31/41 , C07D498/04 , C07D513/04
Abstract: The present invention relates to inhibitors of protein kinases of formula I. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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