Abstract:
본 발명은 타겟팅-금 자성 나노입자 및 이의 용도에 관한 것이다. 본 발명의 나노입자는 (ⅰ) 자성물질을 포함하는 코어, (ⅱ) 금을 포함하는 쉘 및 (ⅲ) 상기 쉘에 결합된 타겟팅 모이어티(targeting moiety)로 이루어져 있으며, 상기 쉘에 결합된 타겟팅 모이어티(예컨대, 타겟 미생물의 표면 항원에 대한 항체)를 이용하여 타겟 미생물을 효과적으로 분리, 농축 및 검출을 원-스텝으로 할 수 있다. 따라서, 본 발명의 자성 나노입자-기반된 방법은 종래의 복잡하고 시간-소모적인 방법들에 비해 미생물의 분리 및 농축을 매우 간편하게 실시할 수 있을 뿐 아니라, 동시에 효율적인 검출도 할 수 있다.
Abstract:
PURPOSE: A method for isolating, concentrating, and detecting targeting-gold magnetic nanoparticles and gold magnetic nanoparticle-based microorganisms in one-step is provided to simultaneously detect target microorganisms in a sample. CONSTITUTION: A method for isolating, concentrating, and detecting microorganisms using gold magnetic nanoparticles comprises: a step of contacting a sample targeting-gold magnetic nanoparticles comprising a core, a shell, and a targeting moiety; and a step of applying the resultant to a column. The magnet is applied by a permanent magnet or electromagnet. The targeting moiety is an antibody or a fragment thereof.
Abstract:
PURPOSE: A hand disinfection composition for enhancing alcohol smell removal is provided to reduce alcohol smell and to prevent food poisoning. CONSTITUTION: A hand disinfection composition contains extract of Agaricus bisporus, Myristicae Semen, Acanthopanax senticosus, Phellodendri Cortex, Caryophylli Flos, Coptidis Rhizoma, barley bud, salary, or Cucumis sativus. The extract is obtained by adding 5-10 times volume of alcohol to the natural products, placing for 20-28 hours, filtering, and compressing. The composition further contains aloe vera and alcohol. The alcohol is ethanol, ethanol amine, or spirit.
Abstract:
PURPOSE: A method for sterilizing food is provided to increase shelf life of the food without damages to a product by sterilizing microorganism in the food including pathogenic microorganism, and to maintain quality of the food. CONSTITUTION: A method for sterilizing food includes a step for adding a natural antimicrobial agent in food and a step for processing the food processed with the natural antimicrobial agent with pressure of 200 ~ 600 MPa. The natural antimicrobial agent comprises grapefruit seed extract, vitamin B1, thiamine dilauryl sulfate, propolis, chitosane, lactic acid, mustard powder, Wasabia japonica, or Japanese apricot which are selected from a group consisting of extract and soluble seaweed calcium. An extra-high voltage process is performed at a temperature of 10 ~ 25 °C. The food is salted seafood.
Abstract:
PURPOSE: A zearalenone-fluorescence tracer for detecting zearalenone and a method for manufacturing method thereof are provided to use widely through massive production. CONSTITUTION: A method for manufacturing a zearalenone-fluorescence tracer for detecting zearalenone through fluorescence-polarized light comprises: a step of inducing oxime group to ketone group in molecular structure of the zearlenone to produce a zearalenone-oxime; a step of reacting a linker compound to synthesize fluorescein derivative; and a step of mixing the synthesized fluorescein derivative to the zearalenone-oxime and maintaining at room temperature for two hours.
Abstract:
PURPOSE: Provided is a process for preparing dry-coated bacteriocin without liquid phase solvent. The prepared dry-coated bacteriocin displays antibacterial activity, has extended storage at normal temperature and is widely used for development of foods and cosmetics containing the bacteriocin as an active ingredient. CONSTITUTION: The process for preparing dry-coated bacteriocin comprises the steps of: mixing bacteriocin and a coating agent in a mixing ratio of 1:1 to 10:1(w/w); inserting the mixture into the hybridization system; and cry-coating the bacteriocin by using the hybridization system.