公开(公告)号：US20160156814A1

公开(公告)日：2016-06-02

申请号：US14945662

申请日：2015-11-19

Applicant: FUJIFILM Corporation

Inventor： Masaki TAKAMATSU ,  Yasunori OHTA

IPC: H04N5/04

CPC classification number: H04N5/04 ,  G01J3/0208 ,  G01J3/0237 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/6456 ,  G01N21/76 ,  G01N35/00871

Abstract: Disclosed are an imaging device, a control method therefor, and an imaging system capable of allowing efficient use by multiple users and achieving improvement of a rate of operation. An imaging device which photoelectrically reads fluorescence or chemiluminescence emitted from an object to image the object includes a control unit which receives first control information for controlling a first function and second control information for controlling, a second function from a plurality of external terminals and performs control based on the received first and second control information. The control unit recognizes the execution states of the first function and the second function in each external terminal based on the first and second control information output from each external terminal, restricts simultaneous processing of the first function in the plurality of external terminals, and performs parallel processing of the first function and the second function in the plurality of external terminals.

Abstract translation: 公开了一种成像装置及其控制方法以及能够允许多个用户有效使用并实现操作速度提高的成像系统。 光电读取从物体发出的成像物体的荧光或化学发光成像装置包括控制单元，其接收用于控制第一功能的第一控制信息和用于从多个外部端子控制第二功能的第二控制信息，并执行控制 基于所接收的第一和第二控制信息。 控制单元基于从每个外部端子输出的第一和第二控制信息来识别每个外部终端中的第一功能和第二功能的执行状态，限制多个外部端子中的第一功能的同时处理，并且并行地执行 多个外部终端中的第一功能和第二功能的处理。

公开(公告)号：US20160103073A1

公开(公告)日：2016-04-14

申请号：US14883269

申请日：2015-10-14

Applicant: Alakai Defense Systems, Inc.

Inventor： Alan R. Ford ,  Adam J. Hopkins

IPC: G01N21/65 ,  G01N33/22

CPC classification number: G01N21/65 ,  G01J3/0224 ,  G01J3/0237 ,  G01J3/0262 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/28 ,  G01J3/44 ,  G01J2003/4424 ,  G01N33/227 ,  G01N2021/1793 ,  G01N2201/0683 ,  G01N2201/121

Abstract: A method for utilizing polarization as a scheme for fluorescence removal from UV Raman spectra collected in a standoff detection scheme has been invented. In this scheme, a linearly polarized ultraviolet (UV) laser interacts with a material on a surface or in a container. The material generates Raman scattering with polarization contributions relative to that of the laser. The material possibly fluoresces as well, but the fluorescence is generally unpolarized. By subtracting a scaled version of the perpendicular component from the parallel component of the returned signal both relative to the laser source polarization—it is possible to generate a spectrum that is fluorescence free and contains the strongest features of the Raman scattered light.

Abstract translation: 已经发明了利用偏振作为在间隔检测方案中收集的UV拉曼光谱进行荧光去除的方案的方法。 在该方案中，线偏振紫外（UV）激光与表面或容器中的材料相互作用。 该材料产生相对于激光的偏振贡献的拉曼散射。 该材料也可能发荧光，但荧光通常是非极化的。 通过从相对于激光源极化的返回信号的并行分量中减去垂直分量的缩放版本，可以产生无荧光的光谱，并且包含拉曼散射光的最强特征。

公开(公告)号：US09297639B2

公开(公告)日：2016-03-29

申请号：US14263031

申请日：2014-04-28

Applicant: Richard Jackson

Inventor： Richard Jackson

IPC: G01B9/02 ,  G01J3/45 ,  G01J3/02 ,  G01J3/453

CPC classification number: G01B9/02049 ,  G01J3/0202 ,  G01J3/0237 ,  G01J3/4535

Abstract: A mechanism that allows for precise motion of the optics of an interferometer is comprised by two or more diaphragm flexures having high lateral stiffness, creating a superior performing Michelson interferometer. When coupled with precise precision control of a mirror surface and a reference laser, the above creates a superior performing Fourier transform spectrometer.

Abstract translation: 允许干涉仪的光学器件的精确运动的机构由具有高横向刚度的两个或更多个隔膜弯曲构成，产生了优异的执行迈克尔逊干涉仪。 当与镜面和参考激光器的精确精确控制相结合时，上述产生了优异的执行傅里叶变换光谱仪。

公开(公告)号：US09279977B2

公开(公告)日：2016-03-08

申请号：US13842996

申请日：2013-03-15

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Christoph Baranec ,  Reed Riddle

IPC: G02B26/06 ,  G02B23/00 ,  G01J3/02 ,  G02B23/02 ,  G02B7/00 ,  G03B21/20 ,  G05B15/02 ,  G01B11/00 ,  G02B23/06 ,  G02B26/08 ,  G02B27/40 ,  G01J9/00 ,  G01J3/32 ,  G01J3/36

CPC classification number: G02B26/06 ,  G01B11/00 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/027 ,  G01J3/32 ,  G01J3/36 ,  G01J9/00 ,  G02B7/003 ,  G02B23/00 ,  G02B23/02 ,  G02B23/06 ,  G02B26/0816 ,  G02B27/40 ,  G03B21/2033 ,  G05B15/02

Abstract: An automated adaptive optics and laser projection system is described. The automated adaptive optics and laser projection system includes an adaptive optics system and a compact laser projection system with related laser guidance programming used to correct atmospheric distortion induced on light received by a telescope. Control of the automated adaptive optics and laser projection system is designed in a modular manner in order to facilitate replication of the system to be used with a variety of different telescopes. Related methods are also described.

Abstract translation: 描述了自动化自适应光学和激光投影系统。 自动适应光学和激光投影系统包括自适应光学系统和紧凑的激光投影系统，其具有用于校正由望远镜接收的光引起的大气失真的相关激光引导程序。 自动适应光学和激光投影系统的控制是以模块化的方式设计的，以便于系统的复制以与各种不同的望远镜一起使用。 还描述了相关方法。

公开(公告)号：US20150377773A1

公开(公告)日：2015-12-31

申请号：US14845997

申请日：2015-09-04

Applicant: THERMO ELECTRON SCIENTIFIC INSTRUMENTS LLC

Inventor： John Magie COFFIN

IPC: G01N21/35

CPC classification number: G01N21/35 ,  G01J3/0237 ,  G01N21/0303 ,  G01N21/15 ,  G01N2201/0668

Abstract: The present invention is thus directed to an automated system of varying the optical path length in a sample that a light from a spectrophotometer must travel through. Such arrangements allow a user to easily vary the optical path length while also providing the user with an easy way to clean and prepare a transmission cell for optical interrogation. Such path length control can be automatically controlled by a programmable control system to quickly collect and stores data from different path lengths as needed for different spectrographic analysis. Moreover, the system utilizes configured wedge shaped windows to best minimize the reflections of light which cause periodic variation in transmission at different wave lengths (commonly described as “channel spectra”). Such a system, as presented herein, is able to return best-match spectra with far fewer computational steps and greater speed than if all possible combinations of reference spectra are considered.

公开(公告)号：US20150377705A1

公开(公告)日：2015-12-31

申请号：US14317132

申请日：2014-06-27

Applicant: David N. Hutchison ,  Kyu Hyun Kim ,  Haisheng Rong ,  John Heck ,  Shengbo Xu

Inventor： David N. Hutchison ,  Kyu Hyun Kim ,  Haisheng Rong ,  John Heck ,  Shengbo Xu

IPC: G01J3/28 ,  G01J3/18 ,  G01J3/02 ,  G02B6/42

CPC classification number: G02B6/4295 ,  G01J3/0218 ,  G01J3/0237 ,  G01J3/0259 ,  G01J3/0297 ,  G01J3/1809 ,  G01J3/1895 ,  G01J3/20 ,  G01J3/32 ,  G02B6/00 ,  G02B6/12033

Abstract: Techniques and mechanisms for a monolithic photonic integrated circuit (PIC) to provide spectrometry functionality. In an embodiment, the PIC comprises a photonic device, a first waveguide and a second waveguide, wherein one of the first waveguide and the second waveguide includes a released portion which is free to move relative to a substrate of the PIC. During a metering cycle to evaluate a material under test, control logic operates an actuator to successively configure a plurality of positions of the released portion relative to the photonic device. In another embodiment, light from the first waveguide is variously diffracted by a grating of the photonic device during the metering cycle, where portions of the light are directed into the second waveguide. Different wavelengths of light diffracted into the second waveguide may be successively detected, for different positions of the released portion, to determine spectrometric measurements over a range of wavelength.

Abstract translation: 单片光子集成电路（PIC）提供光谱功能的技术和机制。 在一个实施例中，PIC包括光子器件，第一波导和第二波导，其中第一波导和第二波导中的一个包括相对于PIC的衬底自由移动的释放部分。 在用于评估被测材料的计量循环期间，控制逻辑操作致动器以相对于光子器件连续配置释放部分的多个位置。 在另一个实施例中，来自第一波导的光在计量周期期间由光子器件的光栅进行各种衍射，其中光的一部分被引导到第二波导中。 对于释放部分的不同位置，可以连续地检测衍射到第二波导中的不同波长的光，以确定波长范围上的光谱测量。

公开(公告)号：US20150285686A1

公开(公告)日：2015-10-08

申请号：US14438641

申请日：2013-10-24

Applicant: APPLIED SPECTRAL IMAGING LTD.

Inventor： Nir Katzir

IPC: G01J3/453 ,  G01J3/28 ,  G02B27/14

CPC classification number: G01J3/4532 ,  G01J3/0237 ,  G01J3/0297 ,  G01J3/2823 ,  G01J3/45 ,  G02B27/144

Abstract: A method of calibrating a spectral imaging system is disclosed. The spectral imaging system comprises an interferometer having a beam splitter and at least a first reflector and a second reflector. The method comprises: obtaining data pertaining to an interference pattern model, operating the spectral imaging system to provide an interference pattern of a received light beam, and varying a relative orientation between at least two of: the beam splitter, the first reflector and the second reflector, until the interference pattern of the input light beam substantially matches the interference pattern model.

Abstract translation: 公开了一种校准光谱成像系统的方法。 光谱成像系统包括具有分束器和至少第一反射器和第二反射器的干涉仪。 该方法包括：获得与干涉图案模型相关的数据，操作光谱成像系统以提供接收光束的干涉图案，以及改变以下中的至少两个之间的相对取向：分束器，第一反射器和第二反射器 反射器，直到输入光束的干涉图案基本上与干涉图案模型相匹配。

公开(公告)号：US09151671B2

公开(公告)日：2015-10-06

申请号：US13975693

申请日：2013-08-26

Applicant: John Magie Coffin

Inventor： John Magie Coffin

IPC: G01N1/10 ,  G01J3/02 ,  G01N21/03 ,  G01N21/15

CPC classification number: G01N21/35 ,  G01J3/0237 ,  G01N21/0303 ,  G01N21/15 ,  G01N2201/0668

Abstract: The present invention is thus directed to an automated system of varying the optical path length in a sample that a light from a spectrophotometer must travel through. Such arrangements allow a user to easily vary the optical path length while also providing the user with an easy way to clean and prepare a transmission cell for optical interrogation. Such path length control can be automatically controlled by a programmable control system to quickly collect and stores data from different path lengths as needed for different spectrographic analysis. Moreover, the system utilizes configured wedge shaped windows to best minimize the reflections of light which cause periodic variation in transmission at different wave lengths (commonly described as “channel spectra”). Such a system, as presented herein, is able to return best-match spectra with far fewer computational steps and greater speed than if all possible combinations of reference spectra are considered.

Abstract translation: 因此，本发明涉及一种自动化系统，其改变来自分光光度计必须穿过的光的样品中的光程长度。 这样的布置允许用户容易地改变光路长度，同时还为用户提供了清洁和准备用于光询问的传输单元的简单方法。 这种路径长度控制可以由可编程控制系统自动控制，以便根据不同光谱分析的需要快速收集和存储来自不同路径长度的数据。 此外，该系统利用配置的楔形窗口来最大程度地最小化导致在不同波长（通常被描述为“通道光谱”）的传输中周期性变化的光的反射。 如本文所提出的，如果考虑到所有可能的参考光谱组合，这样一个系统就能够以更少的计算步骤和更高的速度返回最佳匹配光谱。

公开(公告)号：US20150138533A1

公开(公告)日：2015-05-21

申请号：US14085840

申请日：2013-11-21

Applicant: Agilent Technologies, Inc.

Inventor： Michael Bolles ,  Michael Ron Hammer

IPC: G01J3/427

CPC classification number: G01J3/427 ,  G01J3/021 ,  G01J3/0237 ,  G01J3/10 ,  G01J3/12 ,  G01J3/36 ,  G01J3/42 ,  G01J2003/1876

Abstract: An optical absorption spectrometry system includes first and second light sources, a dichroic beam combiner and a wavelength selective module. The first light source emits first light having first wavelengths within a first wavelength range, and the second light source emits second light having second wavelengths within a second wavelength range different from the first wavelength range. The dichroic beam combiner includes a predetermined first reflectance/transmission transition region, the dichroic beam combiner being configured to transmit a first portion of the first light and to reflect a second portion of the second light to provide combined light. The wavelength selective module is configured to disperse the combined light received at an entrance aperture, to select a sample wavelength range of the dispersed light as sample light, and to output the sample light having the selected sample wavelength range from an exit aperture for illuminating a sample.

Abstract translation: 光吸收光谱系统包括第一和第二光源，二向色光束组合器和波长选择模块。 第一光源发射具有在第一波长范围内的第一波长的第一光，并且第二光源发射具有不同于第一波长范围的第二波长范围内的第二波长的第二光。 二向色光束组合器包括预定的第一反射/透射过渡区域，二向色光束组合器被配置为透射第一光的第一部分并反射第二光的第二部分以提供组合光。 波长选择模块被配置为分散接收在入射孔处的组合光，以选择分散光的样本波长范围作为样本光，并且从出射孔输出具有选择的样本波长范围的样本光，以便照射 样品。

公开(公告)号：US20150109617A1

公开(公告)日：2015-04-23

申请号：US14397814

申请日：2013-04-29

Applicant: Mayo Foundation for Medical Education and Research

Inventor： Barry K. Gilbert ,  Clifton R. Haider ,  Gary S. Delp ,  James A. Rose

IPC: G01J3/42 ,  G01N33/49 ,  G01J3/02

CPC classification number: G01J3/42 ,  A61B5/0075 ,  A61B5/14532 ,  A61B5/14552 ,  G01J3/0237 ,  G01N21/49 ,  G01N33/4925

Abstract: A system and method of dynamically localizing a measurement of parameter characterizing tissue sample with waves produced by spectrometric system at multiple wavelengths and detected at a fixed location of the detector of the system. The parameter is calculated based on impulse response of the sample, reference data representing characteristics of material components of the sample, and path lengths through the sample corresponding to different wavelengths. Dynamic localization is effectuated by considering different portions of a curve representing the determined parameter, and provides for the formation of a spatial map of distribution of the parameter across the sample. Additional measurement of impulse response at multiple detectors facilitates determination of change of the measured parameter across the sample as a function of time.

Abstract translation: 一种系统和方法，用于通过在多个波长处的光谱测量系统产生的波形来动态地定位参数表征组织样本的测量并在系统的检测器的固定位置处检测。 该参数基于样品的脉冲响应，表示样品的材料成分的特征的参考数据和对应于不同波长的样品的路径长度来计算。 通过考虑表示确定的参数的曲线的不同部分来实现动态定位，并且提供在样本上形成参数分布的空间图。 在多个检测器处的​​脉冲响应的附加测量有助于确定作为时间的函数的样品上的测量参数的变化。