公开(公告)号：US20240264146A1

公开(公告)日：2024-08-08

申请号：US18566380

申请日：2022-06-03

Applicant: Ricardo Daniel DE SIMONE

Inventor： Ricardo Daniel DE SIMONE

IPC: G01N33/497 ,  G01J3/443 ,  G01N1/44 ,  G01N21/67 ,  G06V10/774 ,  G06V20/69

CPC classification number: G01N33/4975 ,  G01J3/443 ,  G01N1/44 ,  G01N21/67 ,  G06V10/774 ,  G06V20/69

Abstract: The present invention relates to instruments and processes for detecting compounds in gas samples. In particular, for detecting health disorders from biological samples, more preferably for detecting diseases from breath samples of a mammal. It is included among the methods and instruments for the diagnosis of COVID-19.

公开(公告)号：US12002185B2

公开(公告)日：2024-06-04

申请号：US17309027

申请日：2019-06-10

Applicant: Purdue Research Foundation

Inventor： Peiyi Zhang ,  Fang Huang ,  Sheng Liu

IPC: G06T3/40 ,  G01J3/28 ,  G01J3/443 ,  G01N21/64 ,  G06N3/08 ,  G06T3/4046

CPC classification number: G06T3/4046 ,  G01J3/2823 ,  G01J3/443 ,  G01N21/6428 ,  G01N21/6458 ,  G06N3/08

Abstract: A fluorescent single molecule emitter simultaneously transmits its identity, location, and cellular context through its emission patterns. A deep neural network (DNN) performs multiplexed single-molecule analysis to enable retrieving such information with high accuracy. The DNN can extract three-dimensional molecule location, orientation, and wavefront distortion with precision approaching the theoretical limit of information content of the image which will allow multiplexed measurements through the emission patterns of a single molecule.

公开(公告)号：US11948774B2

公开(公告)日：2024-04-02

申请号：US17223941

申请日：2021-04-06

Applicant: Servomex Group Limited

Inventor： Bahram Alizadeh ,  Martin Lopez

IPC: H01J37/32 ,  G01J3/443 ,  G01N21/67 ,  G01N21/68 ,  H05H1/00 ,  H05H1/24 ,  H05H1/46

CPC classification number: H01J37/32045 ,  G01J3/443 ,  G01N21/67 ,  G01N21/68 ,  H01J37/32018 ,  H01J37/32449 ,  H01J37/32926 ,  H01J37/32935 ,  H01J37/32981 ,  H05H1/0037 ,  H05H1/4697 ,  H01J37/32568 ,  H01J37/32972 ,  H01J37/3299 ,  H01J2237/334

Abstract: Methods and apparatus for determination of the gas composition of a sample gas using glow discharge optical emission spectroscopy, in which the method comprises: generating one or more oscillating electromagnetic fields within a plasma cell to excite particles within the cell, to produce a glow discharge plasma in the plasma cell, and controlling the operating conditions for the plasma cell while flowing a gas mixture through the plasma cell to maintain glow discharge optical emissions from the plasma within a desired operating range; and monitoring one or more glow discharge optical emissions from the plasma in the plasma cell by measuring the optical emissions, or measuring a signal that correlates with the optical emissions, at twice the plasma excitation frequency; and processing the signal during each excitation cycle of the electromagnetic excitation, to determine the concentration of a gas within a gas mixture flowing through the plasma cell.

公开(公告)号：US11940325B2

公开(公告)日：2024-03-26

申请号：US17870051

申请日：2022-07-21

Applicant: The Penn State Research Foundation

Inventor： Abdalla R. Nassar ,  Alexander J. Dunbar ,  Edward W. Reutzel

IPC: G01J3/02 ,  B22F10/20 ,  B22F10/25 ,  B22F10/28 ,  B22F12/44 ,  B22F12/45 ,  B22F12/90 ,  B33Y50/02 ,  G01J3/36 ,  G01J3/443 ,  B22F10/30 ,  B22F10/366 ,  B22F10/38 ,  B33Y10/00 ,  G01J3/12

CPC classification number: G01J3/36 ,  B22F10/20 ,  B22F10/25 ,  B22F10/28 ,  B22F12/44 ,  B22F12/45 ,  B22F12/90 ,  B33Y50/02 ,  G01J3/0208 ,  G01J3/443 ,  B22F10/30 ,  B22F10/366 ,  B22F10/38 ,  B33Y10/00 ,  G01J2003/1213

Abstract: Embodiments of the systems can be configured to receive electromagnetic emissions of a substrate (e.g., a build material of a part being made via additive manufacturing) by a detector (e.g., a multi-spectral sensor) and generate a ratio of the electromagnetic emissions to perform spectral analysis with a reduced dependence on location and orientation of a surface of the substrate relative to the multi-spectral sensor. The additive manufacturing process can involve use of a laser to generate a laser beam for fusion of the build material into the part. The system can be configured to set the multi-spectral sensor off-axis with respect to the laser (e.g., an optical path of the multi-spectral sensor is at an angle that is different than the angle of incidence of the laser beam). This can allow the multi-spectral sensor to collect spectral data simultaneously as the laser is used to build the part.

公开(公告)号：US11927482B2

公开(公告)日：2024-03-12

申请号：US17604814

申请日：2020-03-27

Applicant: Applied Materials, Inc.

Inventor： Kin Pong Lo ,  Lara Hawrylchak ,  Malcolm J. Bevan ,  Theresa Kramer Guarini ,  Wei Liu ,  Bernard L. Hwang

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/10 ,  G01J3/443

CPC classification number: G01J3/10 ,  G01J3/0218 ,  G01J3/443 ,  G01J2003/2879

Abstract: One or more embodiments described herein generally relate to systems and methods for calibrating an optical emission spectrometer (OES) used for processing semiconductor substrates. In embodiments herein, a light fixture is mounted to a plate within a process chamber. A light source is positioned within the light fixture such that it provides an optical path that projects directly at a window through which the OES looks into the process chamber for its reading. When the light source is on, the OES measures the optical intensity of radiation from the light source. To calibrate the OES, the optical intensity of the light source is compared at two separate times when the light source is on. If the optical intensity of radiation at the first time is different than the optical intensity of radiation at the second time, the OES is modified.

公开(公告)号：US11917744B2

公开(公告)日：2024-02-27

申请号：US17383060

申请日：2021-07-22

Applicant: PERKINELMER SCIENTIFIC CANADA ULC

Inventor： Tak Shun Cheung ,  Chui Ha Cindy Wong ,  William Fisher ,  Hamid Badiei

IPC: H05H1/28 ,  H01J49/10 ,  H05H1/46 ,  H01J49/04 ,  G01J3/44 ,  G01J3/443

CPC classification number: H05H1/28 ,  H01J49/0468 ,  H01J49/105 ,  H05H1/4652 ,  G01J3/443

Abstract: A system for cooling an inductively coupled plasma (ICP) instrument includes: the ICP instrument; a pump in fluid communication with the instrument via a first conduit; and a micro-channel heat exchanger in fluid communication with the instrument via a second conduit, and in fluid communication with the pump via a third conduit. The pump is configured to generate a pump outlet pressure of coolant that exceeds a back pressure of the instrument such that a pressure of the coolant traveling through the second conduit and into the heat exchanger is less than or equal to 5 pounds per square inch (psi) above atmospheric pressure, as measured at an inlet to the heat exchanger.

公开(公告)号：US20240062334A1

公开(公告)日：2024-02-22

申请号：US18493899

申请日：2023-10-25

Applicant: Purdue Research Foundation

Inventor： Peiyi Zhang ,  Fang Huang ,  Sheng Liu

IPC: G06T3/40 ,  G01J3/28 ,  G01J3/443 ,  G01N21/64 ,  G06N3/08

CPC classification number: G06T3/4046 ,  G01J3/2823 ,  G01J3/443 ,  G01N21/6428 ,  G01N21/6458 ,  G06N3/08

Abstract: A fluorescent single molecule emitter simultaneously transmits its identity, location, and cellular context through its emission patterns. A deep neural network (DNN) performs multiplexed single-molecule analysis to enable retrieving such information with high accuracy. The DNN can extract three-dimensional molecule location, orientation, and wavefront distortion with precision approaching the theoretical limit of information content of the image which will allow multiplexed measurements through the emission patterns of a single molecule.

公开(公告)号：US11892353B2

公开(公告)日：2024-02-06

申请号：US17883724

申请日：2022-08-09

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

CPC classification number: G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/0215 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  F17C2221/033 ,  F17C2227/0164 ,  F17C2227/0185 ,  F17C2227/0339 ,  F17C2227/0348 ,  F17C2227/0358 ,  F17C2265/033 ,  F17C2265/034 ,  F17C2265/037 ,  F17C2265/038 ,  F17C2265/066 ,  F17C2270/0105 ,  G01J2003/423 ,  G01N21/718

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US20240003817A1

公开(公告)日：2024-01-04

申请号：US18343461

申请日：2023-06-28

Applicant: Hitachi High-Tech Analytical Science GmbH

Inventor： André PETERS

IPC: G01N21/73 ,  G01N21/67 ,  G01J3/443

CPC classification number: G01N21/73 ,  G01N21/67 ,  G01J3/443

Abstract: A spark stand assembly for an optical emission spectroscopy includes: a spark stand body on a mounting flange enabling attaching the assembly to a main housing; an exciter in a recess on the body; an elevated portion on the body adjacent the mounting flange; an elongated notch on the body connecting the recess to a passageway through the elevated portion; a spark stand plate on the body to cover the recess, the notch and part of the elevated portion so the recess forms a plasma chamber and the notch forms a path to the passageway. The plate includes an opening exposing part of a sample on the opening for excitation, the opening being spatially aligned with the exciter when the plate is on the body; and a sealing member between the top of the body and the plate enclosing the recess and notch and routed over the elevated portion.

公开(公告)号：US11860107B2

公开(公告)日：2024-01-02

申请号：US17431370

申请日：2020-05-20

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jai Ick Yoh ,  Jun Ho Yang ,  Jae Hun Jung

IPC: G01N21/68 ,  G01N15/02 ,  G01J3/443 ,  G01N21/73

CPC classification number: G01N21/68 ,  G01J3/443 ,  G01N15/0227 ,  G01N21/73

Abstract: A device and a method of detecting a concentration of a sample are provided. The device includes a power supply unit configured to supply power to generate plasma, a plasma generation unit connected to the power supply unit and including a pair of electrodes facing each other, a plurality of signal detection units arranged on the pair of electrodes and configured to sense light emitted from the sample because of the plasma, and a controller configured to control a driving start point of the signal detection unit so that the signal detection unit is driven after a preset period of time after oscillation is terminated between the pair of electrodes.