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公开(公告)号:US10852185B2
公开(公告)日:2020-12-01
申请号:US16493103
申请日:2018-03-23
Applicant: ATONARP INC.
Inventor: Yoshiyuki Ishimitsu
Abstract: An optical head includes a first module that concentrates pump light and Stokes light on a first point; a second module that collects CARS light from the first point; and a third module that supports the first module and the second module. The first module includes: a high rigidity first frame; and a first optical system including a plurality of optical elements fixed to the first frame. The second module includes: a high rigidity second frame; and a second optical system including a plurality of optical elements fixed to the second frame. The third module includes a high rigidity third frame that fixes the first frame and the second frame.
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公开(公告)号:US10517516B2
公开(公告)日:2019-12-31
申请号:US14888093
申请日:2014-05-02
Applicant: ATONARP INC.
Inventor: Prakash Sreedhar Murthy
IPC: A61B5/1455 , A61B5/00
Abstract: Provided is a monitor for monitoring the condition of the interior of a living organism from the surface of the living organism. The monitor is provided with: a probe which includes an observation window and is attached to the organism surface; a unit which irradiates, with a laser, at least a portion of an observation region; a unit which detects scattered light resulting from the laser irradiation; a Doppler analysis unit and a SORS analysis unit which narrow down the observation spots to a first observation spot; and a CARS analysis unit which obtains the optical spectrum for at least one component, and outputs first information indicating the condition of the organism interior on the basis of the intensity of the spectrum.
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公开(公告)号:US20190221412A1
公开(公告)日:2019-07-18
申请号:US16337126
申请日:2016-10-04
Applicant: ATONARP INC.
Inventor: Karthikeyan Rajan MADATHIL
IPC: H01J49/00 , G06N20/00 , G06F16/901
CPC classification number: H01J49/0036 , G01N27/62 , G06F16/901 , G06N20/00
Abstract: System for quantifying a composition of a target sample based on a scan output of a first type of sensor includes a reference database, a custom database and a set of modules. The set of modules includes an analytical model creation module that creates an analytical model of the first type of sensor, a sample processing module that processes samples that include accurately known compositions using the first type of sensor under a standard pressure condition, a molecular fraction estimation module that estimates molecular fraction of the samples using an estimation method and the analytical model, an analytical model optimization module that optimizes the analytical model by comparing the molecular fraction of the samples with a pre-determined molecular fraction of the samples, and a target composition estimation module that estimates a composition of the target sample based on the scan output using the estimation method with the optimized analytical model.
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公开(公告)号:US20180197725A1
公开(公告)日:2018-07-12
申请号:US15915710
申请日:2018-03-08
Applicant: ATONARP INC.
Inventor: Prakash Sreedhar Murthy
CPC classification number: H01J49/0031 , H01J49/025 , H01J49/06 , H01J49/107 , H01J49/147 , H01J49/20 , H01J49/26 , H01J49/421
Abstract: An analyzer includes: an ionizer unit that ionizes molecules to be analyzed; a filter unit that selectively passes ions generated by the ionizer unit; and a detection unit that detects ions that have passed the filter unit. The detection unit includes a plurality of detection elements disposed in a matrix, and the analyzer further includes a first reconfiguration unit that switches between detection patterns including detection elements to be enabled for detection out of the plurality of detection elements. The ionizer unit includes a plurality of ion sources, and the analyzer further includes a driving control unit that switches the connections of the plurality of ion sources based on changes in characteristics of the ion sources.
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公开(公告)号:US09410928B2
公开(公告)日:2016-08-09
申请号:US14425225
申请日:2013-09-04
Applicant: ATONARP INC.
Inventor: Prakash Sreedhar Murthy
CPC classification number: G01N27/624 , G01N33/1813
Abstract: There is provided a system that detects metal ions in a solution easily and with high precision. Such system includes: a unit that produces a mixed solution by mixing a first solution, which includes a first organic compound that has affinity with metal ions to be measured, and a second solution to be measured and supplies the mixed solution to a container; and a unit that detects the metal ions to be measured in the second solution based on a spectrum obtained by ionizing gas in a head space of the container. An example of the first organic compound is siderophores, such as catechol or AHA. The unit that detects the concentration is an ion mobility sensor and is capable of detecting the concentration of metal ions in a solution in real time.
Abstract translation: 提供了一种能够容易且高精度地检测溶液中的金属离子的系统。 这种系统包括:通过混合第一溶液产生混合溶液的单元,该第一溶液包括与要测量的金属离子具有亲和力的第一有机化合物和待测量的第二溶液,并将混合溶液供应到容器中; 以及基于通过在容器的顶部空间中电离气体而获得的光谱来检测在第二溶液中要测量的金属离子的单元。 第一有机化合物的实例是铁载体,例如邻苯二酚或AHA。 检测浓度的单位是离子迁移率传感器,能够实时检测溶液中金属离子的浓度。
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公开(公告)号:US20240377329A1
公开(公告)日:2024-11-14
申请号:US18292459
申请日:2022-08-08
Applicant: ATONARP INC.
Inventor: Lukas BRUECKNER
Abstract: A system includes an optical path for irradiating a part of a target with the Stokes light pulses, the broadband pump light pulses, and the narrowband pump light pulses synchronously; a modulator that is configured to control the phases of the narrowband pump light pulses; and a detector configured to detect CARS spectrum to acquire sets of CARS spectrum in association with the phases of the narrowband pump light pulses.
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公开(公告)号:US20240341610A1
公开(公告)日:2024-10-17
申请号:US18552696
申请日:2022-03-18
Applicant: ATONARP INC.
Inventor: Prakash Sreedhar MURTHY
CPC classification number: A61B5/0261 , A61B5/062 , A61B5/4839 , A61B5/686 , A61B2562/0238
Abstract: There is provided a living body monitoring system equipped with: an implant that is embedded under the skin of the living body and includes an optical part with a reflective function that is embedded below a target under the skin; and an analyzer apparatus. The analyzer apparatus includes: an irradiating apparatus for irradiating a blood vessel that is a target under the skin of the organism with a laser; and a detector that detects scattered light (CARS light) from the blood vessel via the optical unit of the implanted implant. A biomedical management system equipped with a medication system may also be provided.
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公开(公告)号:US12078611B2
公开(公告)日:2024-09-03
申请号:US18261412
申请日:2022-01-25
Applicant: ATONARP INC.
Inventor: Naoki Takahashi
IPC: H01J49/00 , G01N27/623 , H01J49/04 , H01J49/10 , H01J49/42
CPC classification number: G01N27/623 , H01J49/0422 , H01J49/105 , H01J49/421 , H01J49/429
Abstract: A gas analyzing apparatus includes: an ionization device that generates an ion flow of a sample gas; an analyzer that analyzes the ion flow supplied from the ionization device; a first ion path that non-linearly guides the ion flow from the ionization device to an inlet of the analyzer; and a blocking device for intermittently blocking and releasing, using an electric field or a magnetic field, the ion flow on at least part of a path of the ion flow through the first ion path to a mass filter of the analyzer. It is possible to perform measurement in a state where the ion flow is blocked and measurement in a state where the ion flow is not blocked.
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公开(公告)号:US20240266155A1
公开(公告)日:2024-08-08
申请号:US18442177
申请日:2024-02-15
Applicant: ATONARP INC.
Inventor: Naoki TAKAHASHI , Prakash Sreedhar MURTHY
CPC classification number: H01J37/32981 , H01J37/321 , H01J37/32348 , H01J37/32449 , H01J37/32963 , H01J49/105 , H01J2237/057 , H01J2237/332 , H01J2237/334 , H01J2237/335
Abstract: There is provided a gas analyzer apparatus including: a sample chamber which is equipped with a dielectric wall structure and into which only sample gas to be measured is introduced; a plasma generation mechanism that generates plasma inside the sample chamber, which has been depressurized, using an electric field and/or a magnetic field applied through the dielectric wall structure; and an analyzer unit that analyzes the sample gas via the generated plasma. By doing so, it is possible to provide a gas analyzer apparatus capable of accurately analyzing sample gases, even those including corrosive gas, over a long period of time.
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公开(公告)号:US11942312B2
公开(公告)日:2024-03-26
申请号:US18065656
申请日:2022-12-14
Applicant: ATONARP INC.
Inventor: Naoki Takahashi , Prakash Sreedhar Murthy
CPC classification number: H01J37/32981 , H01J37/321 , H01J37/32348 , H01J37/32449 , H01J37/32963 , H01J49/105 , H01J2237/057 , H01J2237/332 , H01J2237/334 , H01J2237/335
Abstract: There is provided a gas analyzer apparatus including: a sample chamber which is equipped with a dielectric wall structure and into which only sample gas to be measured is introduced; a plasma generation mechanism that generates plasma inside the sample chamber, which has been depressurized, using an electric field and/or a magnetic field applied through the dielectric wall structure; and an analyzer unit that analyzes the sample gas via the generated plasma. By doing so, it is possible to provide a gas analyzer apparatus capable of accurately analyzing sample gases, even those including corrosive gas, over a long period of time.
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