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公开(公告)号：US20220211919A1
公开(公告)日：2022-07-07
申请号：US17701421
申请日：2022-03-22
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Danielle Frankson , Adeniyi O. Aremu , Angelo Fruci , Gregory J. Sherwood , Mary M. Byron , Joseph T. Delaney, JR. , Adam McGraw
Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.
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公开(公告)号：US11324860B2
公开(公告)日：2022-05-10
申请号：US15672674
申请日：2017-08-09
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Danielle Frankson , Adeniyi O. Aremu , Angelo Fruci , Gregory J. Sherwood , Mary M. Byron , Joseph T. Delaney, Jr. , Adam McGraw
Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.
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公开(公告)号：US20200157455A1
公开(公告)日：2020-05-21
申请号：US16683482
申请日：2019-11-14
Applicant: Cardiac Pacemakers, Inc.
Inventor： Danielle Frankson , Joel T. Eggert , Poorva Rajguru , Kate Jensen
IPC: C10M107/50 , C08J7/04 , C10M107/44 , A61L29/14 , A61L29/08
Abstract: A method for making an insertable or implantable medical device including a lubricous coating on a silicone substrate includes treating the silicone substrate with an atmospheric plasma at about atmospheric pressure, the atmospheric plasma formed from a noble gas; applying a solution directly to the treated silicone substrate, the solution including a thermoplastic polyurethane; and heating the silicone substrate and the applied solution to form the lubricous coating on the silicone substrate.
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公开(公告)号：US10335513B2
公开(公告)日：2019-07-02
申请号：US15624102
申请日：2017-06-15
Applicant: Cardiac Pacemakers, Inc.
Inventor： Danielle Frankson , Joseph T. Delaney, Jr. , Mary M. Byron , Adam McGraw , David R. Wulfman , Kylee M. Lersch
Abstract: A coating for a roughened metal surface of an implantable medical device includes a poly(ethylene glycol) disposed on at least a portion of the roughened metal surface, wherein the poly(ethylene glycol) is covalently bonded directly to the roughened metal surface.
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公开(公告)号：US20180207427A1
公开(公告)日：2018-07-26
申请号：US15880221
申请日：2018-01-25
Applicant: CARDIAC PACEMAKERS, INC.
Inventor： Erin Kristen Webb , Thomas Lee Williams , Dana Sachs , Danielle Frankson
CPC classification number: A61N1/375 , A61N1/365 , A61N1/37276 , A61N1/3756 , A61N1/3758
Abstract: An electronics module for use in an Implantable Medical Device (IMD) may include a plurality of electrical components connected to form a circuit that includes a terminal and a potting material that supports the plurality of electrical components. The plurality of electrical components and the potting material together form a circuit sub-module in which the terminal is accessible from outside of the circuit sub-module. A metallic layer that conforms to an outer surface of the circuit sub-module is provided thereon such that the terminal is accessible from outside of the metallic layer.
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Patent Agency Ranking
公开(公告)号：US10029107B1
公开(公告)日：2018-07-24
申请号：US15880221
申请日：2018-01-25
Applicant: CARDIAC PACEMAKERS, INC.
Inventor： Erin Kristen Webb , Thomas Lee Williams , Dana Sachs , Danielle Frankson
Abstract: An electronics module for use in an Implantable Medical Device (IMD) may include a plurality of electrical components connected to form a circuit that includes a terminal and a potting material that supports the plurality of electrical components. The plurality of electrical components and the potting material together form a circuit sub-module in which the terminal is accessible from outside of the circuit sub-module. A metallic layer that conforms to an outer surface of the circuit sub-module is provided thereon such that the terminal is accessible from outside of the metallic layer.
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公开(公告)号：US11660379B2
公开(公告)日：2023-05-30
申请号：US17701421
申请日：2022-03-22
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Danielle Frankson , Adeniyi O. Aremu , Angelo Fruci , Gregory J. Sherwood , Mary M. Byron , Joseph T. Delaney, Jr. , Adam McGraw
IPC: A61L24/00 , B05D3/00 , A61L29/16 , A61L31/06 , A61L31/04 , A61L31/10 , B05D3/06 , B05D3/10 , A61F2/30 , A61L27/28 , B05D3/02
CPC classification number: A61L29/16 , A61F2/30767 , A61L27/28 , A61L31/046 , A61L31/06 , A61L31/10 , B05D3/007 , B05D3/061 , B05D3/108 , A61F2002/30677 , A61L2300/606 , A61L2400/12 , A61L2420/02 , A61M2207/00 , B05D3/0254 , B05D2518/00 , A61L31/10 , C08L71/02 , A61L31/06 , C08L75/04 , A61L31/046 , C08L27/12
Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.
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公开(公告)号：US20210121683A1
公开(公告)日：2021-04-29
申请号：US17076313
申请日：2020-10-21
Applicant: Cardiac Pacemakers, Inc.
Inventor： Jeffrey E. Stahmann , Keith R. Maile , Danielle Frankson , Craig M. Stolen , David J. Ternes
Abstract: An implantable antibacterial barrier device for an elongated medical device, the elongated medical device configured to extend from a first site, through a second site, to a third site. The implantable antibacterial barrier device includes a housing configured to be disposed at the first site, a working electrode configured to be disposed at the second site, and a reference electrode configured to be disposed at the first site. The housing includes barrier circuitry. The working electrode electrically is coupled to the barrier circuitry. The reference electrode is electrically coupled to the barrier circuitry. The barrier circuitry is configured to selectively maintain the working electrode at a negative electrical potential relative to the reference electrode to form an antibacterial barrier.
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公开(公告)号：US10518004B2
公开(公告)日：2019-12-31
申请号：US15843673
申请日：2017-12-15
Applicant: Cardiac Pacemakers, Inc.
Inventor： Mary M. Byron , David R. Wulfman , Angelo Fruci , Adam McGraw , Danielle Frankson , Gregory J. Sherwood , Joseph T. Delaney, Jr. , Adeniyi O. Aremu
Abstract: An implantable drug eluting medical device includes a polymer substrate having a surface, a first plurality of nanofibers, and at least one antimicrobial drug. Each of the first plurality of nanofibers includes a first portion interpenetrated with the surface of the substrate to mechanically fix the nanofiber to the substrate, and a second portion projecting from the surface. The at least one antimicrobial drug is disposed within or among the second portion of the first plurality of nanofibers.
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公开(公告)号：US20180043056A1
公开(公告)日：2018-02-15
申请号：US15673274
申请日：2017-08-09
Applicant: Cardiac Pacemakers, Inc.
Inventor： Danielle Frankson , Joseph T. Delaney, JR. , David R. Wulfman , Adam McGraw , Sarah M. Gruba
CPC classification number: A61L27/12 , A61F2/86 , A61L27/04 , A61L27/047 , A61L27/06 , A61L27/34 , A61L27/54 , A61L2300/102 , A61L2300/214 , A61L2300/404 , A61L2300/412 , C08L71/02
Abstract: A coating for a metal surface, the coating including poly(ethylene glycol) disposed on and covalently bonded directly to at least a portion of the metal surface, and a functional group grafted to at least a portion of the poly(ethylene glycol). The functional group is one of a bioactive functional group and an antimicrobial functional group.
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