Apparatus and method for multiple source excitation Raman spectroscopy

    公开(公告)号:US11874229B2

    公开(公告)日:2024-01-16

    申请号:US17715862

    申请日:2022-04-07

    Abstract: An optical metrology device performs multi-wavelength polarized confocal Raman spectroscopy. The optical metrology device uses a first light source to produce a first light beam with a first wavelength and a second light source to produce a second light beam with a second wavelength. A dichroic beam splitter partially reflects the first light beam and transmits the second light beam to combine the light beams along a same optical axis that is incident on a sample. The dichroic beam splitter directs the Raman response emitted from the sample in response to the first light beam and the second light beam together towards at least one spectrometer and directs the first light beam away from the at least one spectrometer. A chopper may be used to isolate the Raman response to the first and second light beams that is received and spectrally measured by the at least one spectrometer.

    SPECTROMETRY APPARATUS
    12.
    发明公开

    公开(公告)号:US20230332950A1

    公开(公告)日:2023-10-19

    申请号:US18131508

    申请日:2023-04-06

    Abstract: Provided is a spectrometry apparatus that suppresses a reduction in usage efficiency of an irradiation energy of a light. A spectrometry apparatus of the disclosure includes a stage on which a sample is placed, an electromagnetic source that emits an electromagnetic wave, one or a plurality of optical elements that transform a spatial energy distribution of the electromagnetic wave and emit the electromagnetic wave, and a reflective objective lens that collects the electromagnetic wave after a transformation of the spatial energy distribution and irradiates the sample with the collected electromagnetic wave.

    Method and Apparatus for Light-Weight, Non-Invasive, Point of Care Diabetes Screening Device

    公开(公告)号:US20190200904A1

    公开(公告)日:2019-07-04

    申请号:US16312080

    申请日:2018-05-22

    Applicant: Rijul GUPTA

    Inventor: Rijul GUPTA

    Abstract: A multi-channel measurement device for measuring properties of human tissue, may comprise a microcontroller and first and second source/sensor complexes. The first source/sensor complex may include a first housing having a first measurement portion, a first light sensor coupled to the microcontroller and exposed to the first measurement portion, and a first plurality of light sources coupled to the microcontroller and exposed to the first measurement portion. The second source/sensor complex may include a second housing having a second measurement portion, a second light sensor coupled to the microcontroller and exposed to the second measurement portion, and a second plurality of light sources coupled to the microcontroller and exposed to the second measurement portion. The first and second source/sensor complexes are coupled to each other such that the first measurement portion is opposite the second measurement portion and human tissue may be placed between the the first and second measurement portions. The microprocessor is configured with instructions stored in non-volatile memory to individually activate each of the light sources of the first and second pluralities of light sources and to record light intensity detected by the first and second light sources while an individual light source is activated. Each combination of an individually activated light source and one of the first and second light sensors provides a distinct measurement channel for measuring the absorption spectra of human blood and tissue.

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