公开(公告)号：US5026160A

公开(公告)日：1991-06-25

申请号：US417623

申请日：1989-10-04

Applicant: Paul B. Dorain ,  Judith B. Snow

Inventor： Paul B. Dorain ,  Judith B. Snow

IPC: G01J3/02 ,  G01J3/18 ,  G01J3/24 ,  G01J3/28

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/0221 ,  G01J3/0259 ,  G01J3/0294 ,  G01J3/18 ,  G01J3/0256 ,  G01J3/1804 ,  G01J3/24 ,  G01J3/2803

Abstract: A solid monolithic spectrograph utilizes the Czerny-Turner geometric confration. It has a base constructed of BK7 optical glass to which all components are affixed with optical epoxy. The compact spectrograph operates in the visible spectrum in second order thereby permitting it to be smaller by a factor of two than if it operated in first order. The spectrograph is programmable and is capable of simultaneous multi-channel measurements of wavelengths and bandwidths of sources in the visible and near infrared spectral regions.

Abstract translation: 固体单片光谱仪采用Czerny-Turner几何配置。 它具有由BK7光学玻璃构成的基座，所有部件都用光学环氧树脂固定。 紧凑型光谱仪在可见光谱中以二次方式操作，从而允许其比以一级操作的方式更小二倍。 光谱仪是可编程的，并且能够同时对可见光和近红外光谱区域中的光源的波长和带宽进行多通道测量。

公开(公告)号：US4035086A

公开(公告)日：1977-07-12

申请号：US682718

申请日：1976-05-03

Applicant: Dietmar M. Schoeffel ,  Armin K. Sonnenschein

Inventor： Dietmar M. Schoeffel ,  Armin K. Sonnenschein

IPC: G01J1/36 ,  G01J3/02 ,  G01N21/05 ,  G01N21/31 ,  G01N21/64 ,  G01N30/74 ,  G01N21/22

CPC classification number: G01N30/74 ,  G01J1/36 ,  G01N21/314 ,  G01J3/0256 ,  G01N2021/1748 ,  G01N2021/6482 ,  G01N2030/746 ,  G01N21/05 ,  G01N21/64

Abstract: Multi-channel analyzer for the optical comparison of sample fractions separated by liquid chromatography for detecting differences or ratios between, for example, reference and sample, solvent and sample, buffer and sample, or two different samples, having a single light source, a single dispersing element and a single collimating, refocusing optic for each spectrum produced, wherein the reference and sample passing through flow cuvettes are exposed and the ratio or difference between the optical characteristics of the reference and the sample are read.

Abstract translation: 用于通过液相色谱法分离的样品级分的光学比较的多通道分析仪，用于检测例如参考和样品，溶剂和样品，缓冲液和样品之间的差异或比例，或具有单个光源的两个不同样品 分散元件和单个准直的重新聚焦光学元件，其中通过流动比色皿的参考和样品被暴露，并且读取参考和样品的光学特性之间的比率或差异。

公开(公告)号：US4007989A

公开(公告)日：1977-02-15

申请号：US618308

申请日：1975-09-29

Applicant: Edward S. Wajda

Inventor： Edward S. Wajda

IPC: G01J3/42 ,  G01J3/02 ,  G01J3/04 ,  G01J3/28 ,  G01J3/30 ,  G01J3/457 ,  G01N21/27 ,  G01N21/31

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0256 ,  G01J3/2846

Abstract: An improved Hadamard filter is disposed between the dispersive element and detector of a Hadamard transform spectrometer. The detector has a series of linear photo-active diode elements arranged in the focal plane of an array of optical lenses. The lenses may be a series of Fly's-Eye lenses with each series arranged to overlay the corresponding linear element of the detector, or may be a cylindrical lens overlying a corresponding detector element. Individual lenses of the Fly's-Eye lens or individual elements of the cylindrical lens are selectively masked according to the desired matrix so as to perform the Hadamard transform spectrometry.

Abstract translation: 改进的Hadamard滤波器设置在Hadamard变换光谱仪的色散元件和检测器之间。 检测器具有布置在光学透镜阵列的焦平面中的一系列线性光电二极管元件。 透镜可以是一系列Fly's-Eye透镜，每个系列布置成覆盖检测器的相应的线性元件，或者可以是覆盖相应的检测器元件的柱面透镜。 根据所需的矩阵选择性地掩盖了Fly's-Eye透镜或柱面透镜的各个元件的单独透镜，以便执行Hadamard变换光谱。

公开(公告)号：US12125835B2

公开(公告)日：2024-10-22

申请号：US18083619

申请日：2022-12-19

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Chee-Pin T'Ng ,  Sai-Mun Lee

IPC: H01L25/16 ,  G01J1/02 ,  G01J3/02 ,  G01J3/10 ,  G01S7/481 ,  G01S17/04 ,  H01L25/00

CPC classification number: H01L25/167 ,  G01J1/0214 ,  G01J3/0227 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/108 ,  G01S7/4813 ,  G01S17/04 ,  H01L25/50 ,  H01L2924/0002 ,  H01L2924/0002 ,  H01L2924/00

Abstract: There is provided a module package including a substrate, a photo sensor chip, a molded transparent layer and a glass filter. The substrate has an upper surface. The photo sensor chip is attached to the upper surface of the substrate and electrically connected to the substrate. The molded transparent layer covers the photo sensor chip and a part of the upper surface of the substrate, wherein a top surface of the molded transparent layer is formed with a receptacle opposite to the photo sensor chip. The glass filter is accommodated in the receptacle.

公开(公告)号：US12061116B2

公开(公告)日：2024-08-13

申请号：US17876250

申请日：2022-07-28

Applicant: Si-Ware Systems

Inventor： Yasser M. Sabry ,  Mohamed H. Al Haron ,  Bassem Mortada ,  Ahmed Othman ,  Diaa Khalil ,  Bassam Saadany ,  Ahmed Shebl ,  Botros George Iskander Shenouda

IPC: G01J3/02 ,  G01J3/10 ,  G01J3/28 ,  G01J3/45 ,  G01J3/453 ,  G01N33/483

CPC classification number: G01J3/0256 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0286 ,  G01J3/108 ,  G01J3/45 ,  G01J3/4532 ,  G01N33/4833 ,  G01J2003/283 ,  G01J2003/2873 ,  G01J2003/4534

Abstract: Aspects relate to a spectral analyzer that can be used for biological sample detection. The spectral analyzer includes an optical window configured to receive a sample and a spectral sensor including a chassis having various component assembled thereon. Examples of components may include a light source, a light modulator, illumination and collection optical elements, a detector, and a processor. The spectral analyzer is configured to obtain spectral data representative of a spectrum of the sample using, for example, an artificial intelligence (AI) engine. The spectral analyzer further includes a thermal separator positioned between the light modulator and the light source.

公开(公告)号：US20240183711A1

公开(公告)日：2024-06-06

申请号：US18441250

申请日：2024-02-14

Applicant: MetGen, Incorporated

Inventor： Richard D. Shunnarah ,  Hugh F. Garvey ,  Lenzi J. williams ,  Devon Fish

IPC: G01J3/02 ,  G01J3/44 ,  G01N21/65 ,  G01N33/52 ,  G01N33/68

CPC classification number: G01J3/0272 ,  G01J3/0256 ,  G01J3/4412 ,  G01N21/658 ,  G01N33/523 ,  G01N33/6812

Abstract: A handheld Surface-Enhanced Raman Spectroscopy (SERS) device for detecting a biomarker in a sample collected from a subject. The device comprises a laser generator configured to produce a laser beam; a nanoporous anodic aluminum oxide (NAAO) substrate configured to receive the sample collected from the subject; wherein the laser beam reaches the sample on the NAAO substrate and is reflected or deflected to produce a light signal; and a light sensor configured to receive the light signal reflected or deflected from the sample; wherein the device is handheld and detects the biomarker in the sample; wherein the NAAO substrate comprises a multilayered nanoporous aluminum layer; wherein the multilayered nanoporous aluminum layer comprises a base aluminum layer, and a nanoporous aluminum layer on top of the base aluminum layer; and wherein the nanoporous aluminum layer comprises a plurality of nanocavities.

公开(公告)号：US11933732B2

公开(公告)日：2024-03-19

申请号：US17471139

申请日：2021-09-09

Applicant: UNM Rainforest Innovations

Inventor： Mani Hossein-Zadeh

IPC: G01N1/00 ,  G01J3/02 ,  G01J3/42 ,  G01J3/453 ,  G01N21/77 ,  G01N33/543 ,  G02B6/122 ,  G02B6/125

CPC classification number: G01N21/7703 ,  G01J3/0224 ,  G01J3/0256 ,  G01J3/42 ,  G01J3/453 ,  G01N33/54373 ,  G02B6/1223 ,  G02B6/1225 ,  G02B6/125 ,  G01N2201/0638

Abstract: The present invention provides a sensor having, one or more optical slab waveguides having one or more target regions. The target regions may interact with gas molecules or trap, entrain or capture one or more targets of interest. The optical slab waveguides are adapted to receive one or more input optical beams from one or more light sources to create a plurality of propagating optical waves in optical slab waveguide. The propagating optical waves interact with said one or more target regions to create an optical output wavefront that may be in the form of a diffraction pattern. The target regions may be functionalized with an antibody, polymer, cell, tissue, or biological material.

公开(公告)号：US11933672B2

公开(公告)日：2024-03-19

申请号：US18218669

申请日：2023-07-06

Applicant: MetGen, Incorporated

Inventor： Richard D. Shunnarah ,  Hugh F. Garvey ,  Lenzi J. Williams ,  Devon Fish

IPC: G01J3/02 ,  G01J3/44 ,  G01N21/65 ,  G01N33/52 ,  G01N33/68 ,  G01N33/50

CPC classification number: G01J3/0272 ,  G01J3/0256 ,  G01J3/4412 ,  G01N21/658 ,  G01N33/523 ,  G01N33/6812

Abstract: A method for fabrication of a gold nanoporous anodic aluminum oxide (NAAO) substrate used in coordination with a handheld Surface-Enhanced Raman Spectroscopy (SERS) device for detecting phenylalanine (Phe) in a sample collected from a subject, the method comprising forming a three-phase system on top of a multilayered nanoporous aluminum layer of the gold NAAO substrate; injecting a cosolvent solution into the three-phase system, wherein the cosolvent solution comprises gold nanoparticles; forming a gold layer on top of the multilayered nanoporous aluminum layer, and drying the gold NAAO substrate.

公开(公告)号：US11913868B2

公开(公告)日：2024-02-27

申请号：US17302651

申请日：2021-05-10

Applicant: CYTEK BIOSCIENCES, INC.

Inventor： Ming Yan ,  Yung-Chieh Hsieh ,  David Vrane ,  Eric Chase

IPC: G01N15/00 ,  G01J3/00 ,  G01J1/08 ,  G01N21/47 ,  G01N15/14 ,  G01J3/02 ,  G01J3/36 ,  G01N15/10 ,  G01J3/12

CPC classification number: G01N15/1436 ,  G01J1/08 ,  G01J3/021 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/36 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/47 ,  G01J2003/1213 ,  G01N2015/1006 ,  G01N2015/145

Abstract: In one embodiment, a flow cytometer is disclosed having a compact light detection module. The compact light detection module includes an image array with a transparent block, a plurality of micro-mirrors in a row coupled to a first side of the transparent block, and a plurality of filters in a row coupled to a second side of the transparent block opposite the first side. Each of the plurality of filters reflects light to one of the plurality of micro-mirrors and passes light of a differing wavelength range and each of the plurality of micro-mirrors reflects light to one of the plurality of filters, such that incident light into the image array zigzags back and forth between consecutive filters of the plurality of filters and consecutive micro-mirrors of the plurality of micro-mirrors. A radius of curvature of each of the plurality of micro-mirrors images the fiber aperture onto the odd filters and collimates the light beam on the even filters.

公开(公告)号：US11898910B2

公开(公告)日：2024-02-13

申请号：US17982860

申请日：2022-11-08

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Ho Jun Chang ,  Sung Hyun Nam ,  Alexey Anikanov ,  Yun S Park ,  Eui Seok Shin ,  Woochang Lee

IPC: G01J3/02 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/44

CPC classification number: G01J3/0256 ,  A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/443 ,  A61B5/4872 ,  A61B5/4875 ,  G01J3/021 ,  G01J3/0216 ,  G01J3/44 ,  A61B5/0075

Abstract: A Raman sensor includes a light source assembly having a plurality of light sources configured to emit light to a plurality of skin points of skin, each of the plurality of skin points having a predetermined separation distance from a light collection region of the skin from which Raman scattered light is collected; a light collector configured to collect the Raman scattered light from the light collection region of the skin; and a detector configured to detect the collected Raman scattered light.