公开(公告)号：US08269174B2

公开(公告)日：2012-09-18

申请号：US12719904

申请日：2010-03-09

Applicant: Charles W. Gardner ,  Patrick J. Treado ,  Matthew Nelson ,  Robert Schweitzer

Inventor： Charles W. Gardner ,  Patrick J. Treado ,  Matthew Nelson ,  Robert Schweitzer

IPC: G01J5/02

CPC classification number: G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0256 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/44 ,  G01N21/31 ,  G01N21/6456 ,  G01N21/6486 ,  G01N21/65

Abstract: A method and a portable device for assessing the occurrence of an agent in a sample. A sample is illuminated with photons emanating from a portable device to produce photons reflected, emitted, or absorbed from a set of multiple points in the sample having a defined geometric relationship. The portable device is used to simultaneously illuminate the sample and analyze the photons reflected, emitted, or absorbed from the set of multiple points using spectroscopic methods, including infrared, fluorescence, and UV/visible. The agent assessed may include a hazardous agent, a chemical agent, a biological agent, a microorganism, a bacterium, a protozoan, a virus, and combinations thereof.

Abstract translation: 一种用于评估样品中的试剂的发生的方法和便携式装置。 用便携式设备发出的光子照射样品，以产生从具有确定的几何关系的样品中的一组多个点反射，发射或吸收的光子。 便携式设备用于同时照亮样品并使用包括红外，荧光和紫外/可见光在内的光谱方法分析从该组多个点反射，发射或吸收的光子。 所评估的试剂可以包括危险剂，化学试剂，生物制剂，微生物，细菌，原生动物，病毒及其组合。

公开(公告)号：US20120232404A1

公开(公告)日：2012-09-13

申请号：US13228717

申请日：2011-09-09

Applicant: Shabbir Bakir Bambot ,  Mark Faupel ,  Jonathan David Mongin

Inventor： Shabbir Bakir Bambot ,  Mark Faupel ,  Jonathan David Mongin

IPC: A61B6/00

CPC classification number: A61B5/4331 ,  A61B5/0059 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0077 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/0262 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/28 ,  G01J3/4406 ,  G01J2003/1213 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/31 ,  G01N21/474 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2021/6423 ,  G01N2021/6484 ,  G01N2201/0221

Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics and correlate same to photographic images. Further, the system and method accomplish this measurement rapidly by increasing the light throughput by integrating optics into a hand held unit and avoiding the need for a coherent fiber optic bundle being used. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.

Abstract translation: 提供了一种方法和装置，用于询问，接收和分析至少一种荧光激发波长的全发射光谱，以及至少一种反射测量以确定组织特征并将其与摄影图像相关联。 此外，该系统和方法通过将光学器件集成到手持式单元中并且避免对使用的相干光纤束的需要而增加光通量而快速地完成该测量。 该方法包括用光能照射目标组织的第一部分，形成目标组织的第一图像，用光能照射目标组织的第二部分，对目标反射和/或发射的光能进行光谱测量 基于光谱测量的结果确定目标组织的第二部分的光能量的组织，以及确定靶组织的组织特征。

公开(公告)号：US20120229803A1

公开(公告)日：2012-09-13

申请号：US13397681

申请日：2012-02-16

Applicant: Hiroyuki SANO ,  Kunikazu TAGUCHI

Inventor： Hiroyuki SANO ,  Kunikazu TAGUCHI

IPC: G01J3/00

CPC classification number: G01J3/0291 ,  G01J3/0218 ,  G01J3/0232 ,  G01J3/0262 ,  G01J3/027 ,  G01J3/18 ,  G01J3/2803

Abstract: A spectral characteristic measurement method for measuring spectral characteristics of measured light with higher accuracy is provided. The spectral characteristic measurement method includes causing an optical measurement instrument having detection sensitivity in a first wavelength range to receive light in a second wavelength range which is a part of the first wavelength range, obtaining characteristic information indicating a stray light component from a portion of a first spectrum detected by the optical measurement instrument, that corresponds to a range other than the second wavelength range, and obtaining a pattern indicating a stray light component generated in the optical measurement instrument by subjecting the characteristic information to extrapolation processing as far as the second wavelength range in the first wavelength range.

Abstract translation: 提供了一种用于以更高精度测量测量光的光谱特性的光谱特征测量方法。 光谱特性测量方法包括使具有第一波长范围的检测灵敏度的光学测量仪器接收作为第一波长范围的一部分的第二波长范围内的光，获得指示来自第一波长范围的部分的杂散光分量的特征信息 由光学测量仪器检测到的与第二波长范围以外的范围相对应的第一光谱，并且通过将特征信息进行外推处理，获得指示在光学测量仪器中产生的杂散光分量的图案，直到第二波长 范围在第一波长范围。

公开(公告)号：US08233189B2

公开(公告)日：2012-07-31

申请号：US12042088

申请日：2008-03-04

Applicant: Danny C. Rich

Inventor： Danny C. Rich

IPC: H04N1/46 ,  H04N1/50 ,  G06K9/00

CPC classification number: G01J3/46 ,  G01J3/02 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/462 ,  G01J3/463 ,  G01J3/465 ,  G05B19/042 ,  H04N1/603 ,  Y02P90/265

Abstract: The present invention provides a plurality of representations of color that are stored in an electronic color library and that can be selected by a user. After a color selection is made, a plurality of color ink formulas and/or colorant formulas capable of producing the selected color are provided. Further, other selections can be made to define a substrate or other criteria that can impact the color ink formulas. The user can make a selection among the plurality of color ink formulas and/or colorant formulas. The selected color ink formula(s) (or colorant formula(s)) can be transmitted over a communication network, such as the Internet or a local Intranet to another party, such as an ink manufacturer.

Abstract translation: 本发明提供存储在电子色谱库中并可由用户选择的多种颜色表示。 在进行颜色选择之后，提供能够产生所选颜色的多种彩色墨水配方和/或着色剂配方。 此外，可以进行其他选择以限定可影响彩色墨水配方的基底或其它标准。 用户可以在多种颜色墨水配方和/或着色剂配方中进行选择。 所选择的彩色墨水配方（或着色剂配方）可以通过诸如因特网或本地内联网的通信网络传送到诸如墨水制造商的另一方。

公开(公告)号：US08218143B2

公开(公告)日：2012-07-10

申请号：US12687469

申请日：2010-01-14

Applicant: Neelam Gupta

Inventor： Neelam Gupta

IPC: G01J3/28

CPC classification number: G01J3/1256 ,  A61B5/0097 ,  A61B5/14551 ,  A61B5/14552 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/027 ,  G01J3/2823

Abstract: A method of detecting oxygen and/or chemical content in a subject, comprising generating at least one spectral image of the subject; generating at least one spectral image of a reference object; comparing spectrum from the subject image to the reference image to thereby reveal the relative oxygen content of the subject. A system for determining the level of oxygenation of the blood of a subject body part comprising: a hyperspectral image generator for generating a plurality of spectral images; an image capture device for capturing the spectral images; a processor for generating hyperspectral image cubes such that the spectrum of the body part is extracted and normalized using the spectrum from the reference object to cancel out the spectral response of the light source and the imager; said processor comparing spectral from a subject image to reference images to thereby reveal the relative oxygen content of the subject.

Abstract translation: 一种检测受试者中氧和/或化学含量的方法，包括产生所述受试者的至少一个光谱图像; 生成参考对象的至少一个光谱图像; 将来自对象图像的光谱与参考图像进行比较，从而显示对象的相对氧含量。 一种用于确定被摄体体部分的血液氧合水平的系统，包括：用于产生多个光谱图像的高光谱图像发生器; 用于捕获光谱图像的图像捕获装置; 用于产生高光谱图像立方体的处理器，使得使用来自参考对象的光谱提取和归一化身体部分的光谱，以抵消光源和成像器的光谱响应; 所述处理器将来自对象图像的光谱与参考图像进行比较，从而显示对象的相对氧含量。

公开(公告)号：US08193500B2

公开(公告)日：2012-06-05

申请号：US12935856

申请日：2009-03-27

Applicant: Takashi Iwasaki ,  Masaharu Mogi ,  Shigeki Nakauchi

Inventor： Takashi Iwasaki ,  Masaharu Mogi ,  Shigeki Nakauchi

IPC: G01J5/00

CPC classification number: G01N21/31 ,  G01J3/02 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/2823 ,  G01N21/05 ,  G01N21/3554 ,  G01N21/359 ,  G01N2201/0627

Abstract: A discrimination filtering device includes a filter and a filter having different pass bands, a detection unit, a processing unit, and a result output unit. The detection unit detects an electromagnetic wave from an object that is the target of identification through the filters. The pass band of the filters is designed to be suitable for object discrimination. The processing unit substitutes the output from the detection unit into a discrimination function determined based on the pass band of the filters and the teaching spectrum obtained in advance to infer the group which the object belongs to based on the substituted result.

Abstract translation: 鉴别滤波装置包括具有不同通带的滤波器和滤波器，检测单元，处理单元和结果输出单元。 检测单元通过滤波器检测来自作为识别目标的物体的电磁波。 滤波器的通带被设计为适合于对象辨别。 处理单元将来自检测单元的输出替换为基于滤波器的通带确定的鉴别函数和预先获得的教学频谱，以基于替代结果来推断对象所属的组。

公开(公告)号：US20120090379A1

公开(公告)日：2012-04-19

申请号：US13264419

申请日：2010-04-16

Applicant: Jens Moeller Jensen ,  Arun Krishna ,  Lars Munch ,  Rainer Buchner ,  Thomine Stolberg-Rohr ,  Henrik Gedde Moos

Inventor： Jens Moeller Jensen ,  Arun Krishna ,  Lars Munch ,  Rainer Buchner ,  Thomine Stolberg-Rohr ,  Henrik Gedde Moos

IPC: G01N1/28

CPC classification number: G01N21/3504 ,  G01J1/00 ,  G01J1/10 ,  G01J3/02 ,  G01J3/027 ,  G01J3/36 ,  G01J3/427 ,  G01J5/02 ,  G01J5/10 ,  G01J2003/1213 ,  G01N21/314

Abstract: The invention relates to a sensor having a filter arrangement, downstream of which there is arranged a detector arrangement, and an evaluating device which is connected to the detector arrangement, the filter arrangement has at least a first filter, the suspect filter, which is configured as a band pass filter allowing the passage of a first predetermined band, the suspect band, at least one second filter, the reference filter(s), which is configured as a band pass filter allowing the passage of a second predetermined band(s), the reference band(s), and where the detector arrangement has at least one detector associated with at least one of the filters. The band passes reference filters are distributed above and below the band pass of the suspect filter. The sensor with advantage could be utilized within the IR band, and could advantageously be used to detect CO2.

Abstract translation: 本发明涉及一种具有滤波器装置的传感器，其下游设置有检测器装置，以及连接到检测器装置的评估装置，滤波器装置至少具有第一滤波器，该滤波器配置为可疑滤波器 作为允许第一预定频带通过的带通滤波器，可疑频带，至少一个第二滤波器，被配置为允许通过第二预定频带的带通滤波器的参考滤波器， ，参考频带，以及其中检测器装置具有至少一个与至少一个滤波器相关联的检测器的检测器。 带通过参考滤波器分布在可疑滤波器的带通上方和下方。 有利的传感器可以在IR带内使用，并且可以有利地用于检测CO 2。

公开(公告)号：US08140139B2

公开(公告)日：2012-03-20

申请号：US11599190

申请日：2006-11-14

Applicant: Jeremy Grata ,  Michael N. Pitsakis

Inventor： Jeremy Grata ,  Michael N. Pitsakis

IPC: A61B5/1455

CPC classification number: A61B5/1112 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B2562/0233 ,  G01J1/46 ,  G01J3/02 ,  G01J3/027 ,  G01J3/42 ,  G01N21/359

Abstract: An apparatus for a non-invasive sensing of biological analytes in a sample includes an optics system having at least one radiation source and at least one radiation detector; a measurement system operatively coupled to the optics system; a control/processing system operatively coupled to the measurement system and having an embedded software system; a user interface/peripheral system operatively coupled to the control/processing system for providing user interaction with the control/processing system; and a power supply system operatively coupled to the measurement system, the control/processing system and the user interface system for providing power to each of the systems. The embedded software system of the control/processing system processes signals obtained from the measurement system to determine a concentration of the biological analytes in the sample.

Abstract translation: 用于非侵入式感测样品中生物分析物的装置包括具有至少一个辐射源和至少一个辐射检测器的光学系统; 可操作地耦合到所述光学系统的测量系统; 可操作地耦合到测量系统并具有嵌入式软件系统的控制/处理系统; 可操作地耦合到控制/处理系统的用户界面/外围系统，用于提供与控制/处理系统的用户交互; 以及可操作地耦合到测量系统的电源系统，用于向每个系统提供电力的控制/处理系统和用户界面系统。 控制/处理系统的嵌入式软件系统处理从测量系统获得的信号，以确定样品中生物分析物的浓度。

公开(公告)号：US20120056093A1

公开(公告)日：2012-03-08

申请号：US13064626

申请日：2011-04-04

Applicant: Wade Poteet ,  James Ryles ,  Malcolm Philips

Inventor： Wade Poteet ,  James Ryles ,  Malcolm Philips

IPC: G01T1/20 ,  G01N21/64

CPC classification number: G01J3/4406 ,  G01J3/02 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0278 ,  G01J3/0289 ,  G01J3/42 ,  G01J3/443 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2201/0221

Abstract: A handheld or portable detection system with a high degree of specificity and accuracy, capable of use at small and substantial standoff distances (e.g., greater than 12 inches) is utilized to identify specific substances and mixtures thereof in order to provide information to officials for identification purposes and assists in determinations related to the legality, hazardous nature and/or disposition decision of such substance(s). The system uses a synchronous detector and visible light filter to enhance detection capabilities.

Abstract translation: 利用具有高度特异性和准确性的手持式或便携式检测系统，能够以小而实质的间隔距离（例如，大于12英寸）使用，以识别特定物质及其混合物，以向官员提供信息以进行识别 目的，并协助与此类物质的合法性，危险性质和/或处置决定有关的决定。 该系统使用同步检测器和可见光滤波器来增强检测能力。

公开(公告)号：US08120772B2

公开(公告)日：2012-02-21

申请号：US12611176

申请日：2009-11-03

Applicant: Marcus T. Cicerone ,  Young Jong Lee

Inventor： Marcus T. Cicerone ,  Young Jong Lee

IPC: G01J3/44

CPC classification number: G01J3/4412 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/027 ,  G01J11/00 ,  G01N2021/653

Abstract: Methods and systems are described for suppressing nonresonant background in broadband coherent anti-Stokes Raman scattering (CARS) microscopy and spectroscopy. The methods and systems improve sensitivity and signal to noise ratio in CARS.

Abstract translation: 描述了用于抑制宽带相干反斯托克斯拉曼散射（CARS）显微镜和光谱学中的非共振背景的方法和系统。 方法和系统提高CARS的灵敏度和信噪比。