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公开(公告)号:US09903805B2
公开(公告)日:2018-02-27
申请号:US15647106
申请日:2017-07-11
Applicant: Theodore Peter Rakitzis
Inventor: Theodore Peter Rakitzis
CPC classification number: G01N21/19 , G01J4/02 , G01J4/04 , G01J2004/001 , G01N21/21 , G01N2201/06113 , G01N2201/0636 , G01N2201/067
Abstract: A polarimeter for measuring chirality of a material comprising an optical ring cavity comprising a plurality of reflective elements configured to promote bi-directional propagation of a laser beam within the cavity, a laser-emitting device configured to introduce a first input beam and a second input beam into the cavity, a Faraday rotator, a phase compensator, an acousto-optic modulator configured to shift the frequency of the first output beam, an optical recombination device configured to recombine shifted and unshifted output beams, and first and second detectors configured to receive the recombined beams, wherein the plurality of reflective elements, Faraday rotator, and phase compensator are configured such that light from the first and second input beams passes through a chiral material located within the cavity a sufficient number of times for a measurement of optical rotary dispersion and circular dichroism of light transmitted through the material to be obtained at the detectors.
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公开(公告)号:US09903757B1
公开(公告)日:2018-02-27
申请号:US15275172
申请日:2016-09-23
Applicant: HRL Laboratories, LLC
Inventor: Daniel Yap , Brian Neff
CPC classification number: G01J3/108 , G01J3/0208 , G01J3/42 , G01J2003/102 , G01N21/35 , G01N21/39 , G01N21/94 , G01N2021/399 , G01N2201/067
Abstract: A sensor includes a plurality of transmitter units, a photodetector, and an optical system coupled to the plurality of transmitter units and the photodetector. Each of the transmitter units simultaneously transmits a light beam having a plurality of wavelengths, the optical system directs the light beam from each of the transmitter units onto a same illuminated spot on a probed surface, and the optical system collects light from the same illuminated spot and directs the light to the photodetector.
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公开(公告)号:US20180017502A1
公开(公告)日:2018-01-18
申请号:US15546615
申请日:2016-01-26
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor: Masami MAKUUCHI , Kazuma OGAWA , Akira HAMAMATSU
CPC classification number: G01N21/8806 , G01N21/94 , G01N21/9501 , G01N21/956 , G01N2021/8848 , G01N2201/067
Abstract: The present invention provides an inspection device that is capable of detecting foreign matter with high accuracy, the inspection device including: a light source; an electro-optic element on which light from the light source is incident and which changes a phase of the light into at least two states; and a controller. The controller corrects a phase fluctuation of the electro-optic element itself, using intensity modulation characteristics of the eletro-optic element which are obtained by changing an applied voltage that is input to the electro-optic element.
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公开(公告)号:US20170350803A1
公开(公告)日:2017-12-07
申请号:US15672051
申请日:2017-08-08
Applicant: The Regents of the University of California
Inventor: Bahram Jalali , Eric Diebold , Brandon Buckley
CPC classification number: G01N15/1434 , G01N15/1459 , G01N15/1484 , G01N21/64 , G01N21/6428 , G01N21/6458 , G01N21/6486 , G01N33/537 , G01N2015/1006 , G01N2015/1477 , G01N2021/6421 , G01N2201/067
Abstract: An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector.
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公开(公告)号:US09822410B2
公开(公告)日:2017-11-21
申请号:US15272138
申请日:2016-09-21
Applicant: Pacific Biosciences of California, Inc.
CPC classification number: C12Q1/6874 , B01L3/502707 , B01L3/502715 , B01L2300/0654 , B01L2300/0663 , B01L2300/0816 , B01L2300/168 , B82Y20/00 , C12Q1/6825 , C12Q1/6869 , G01N21/03 , G01N21/0303 , G01N21/05 , G01N21/64 , G01N21/6428 , G01N21/645 , G01N21/6452 , G01N21/6454 , G01N21/6456 , G01N21/648 , G01N21/75 , G01N21/77 , G01N33/54373 , G01N2021/0346 , G01N2021/6434 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/757 , G01N2021/7786 , G01N2201/067 , G01N2201/068 , G01N2201/08 , G02B6/1226 , Y10T436/143333
Abstract: An analytical assembly within a unified device structure for integration into an analytical system. The analytical assembly is scalable and includes a plurality of analytical devices, each of which includes a reaction cell, an optical sensor, and at least one optical element positioned in optical communication with both the reaction cell and the sensor and which delivers optical signals from the cell to the sensor. Additional elements are optionally integrated into the analytical assembly. Methods for forming and operating the analytical system are also disclosed.
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公开(公告)号:US20170315050A1
公开(公告)日:2017-11-02
申请号:US15647106
申请日:2017-07-11
Applicant: Theodore Peter Rakitzis
Inventor: Theodore Peter Rakitzis
IPC: G01N21/21
CPC classification number: G01N21/19 , G01J4/02 , G01J4/04 , G01J2004/001 , G01N21/21 , G01N2201/06113 , G01N2201/0636 , G01N2201/067
Abstract: A polarimeter for measuring chirality of a material comprising an optical ring cavity comprising a plurality of reflective elements configured to promote bi-directional propagation of a laser beam within the cavity, a laser-emitting device configured to introduce a first input beam and a second input beam into the cavity, a Faraday rotator, a phase compensator, an acousto-optic modulator configured to shift the frequency of the first output beam, an optical recombination device configured to recombine shifted and unshifted output beams, and first and second detectors configured to receive the recombined beams, wherein the plurality of reflective elements, Faraday rotator, and phase compensator are configured such that light from the first and second input beams passes through a chiral material located within the cavity a sufficient number of times for a measurement of optical rotary dispersion and circular dichroism of light transmitted through the material to be obtained at the detectors.
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公开(公告)号:US09804094B2
公开(公告)日:2017-10-31
申请号:US14383119
申请日:2012-11-20
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor: Yoshinobu Kohara , Yuzuru Takamura
CPC classification number: G01N21/67 , G01N21/05 , G01N2201/067 , G01N2201/08
Abstract: To improve the detection sensitivity, detection accuracy, and reproducibility when electrostatic discharge is generated in a sample solution and analysis is performed using light emission in the generated plasma. A flow channel 100, which has cylindrical main portions each expanding conically from a narrow portion, is filled with a conductive sample solution, and an electric field is applied to the flow channel 100 to generate plasma in the generated air bubbles, so that the resulting light emission is measured.
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公开(公告)号:US20170292875A1
公开(公告)日:2017-10-12
申请号:US15516671
申请日:2015-10-02
Applicant: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Jongin Song , Hajun Song
IPC: G01J3/10 , H01S3/23 , H01S3/00 , G01N21/3581 , G01N21/39
CPC classification number: G01J3/108 , G01N21/3581 , G01N21/39 , G01N2201/06113 , G01N2201/067 , G02F1/3534 , G02F2203/13 , H01S3/0085 , H01S3/2308
Abstract: An embodiment of the present invention provides a continuous-wave terahertz generation and detection device using a photomixing technique, the device including: first and second light source units configured to output continuous-wave laser light sources, which have single wavelength and different frequencies, to generate optical signals; a first electro-optic phase modulator configured to shift a frequency of the optical signal generated by the first light source unit, and a second electro-optic phase modulator configured to shift a frequency of the optical signal generated by the second light source unit; a first optical amplifier configured to receive and amplify the optical signal whose frequency is shifted by the first electro-optic phase modulator and the optical signal generated by the second light source unit, and a second optical amplifier configured to receive and amplify the optical signal whose frequency is shifted by the second electro-optic phase modulator and the optical signal generated by the first light source unit; an opto-electronic converter configured to convert the optical signal amplified by the first optical amplifier into a terahertz wave; a photomixer configured to mix the optical signal amplified by the second optical amplifier and the terahertz wave generated by the opto-electronic converter and convert the mixed signal into an electrical signal; a photodetector configured to combine the optical signals transferred from the first and second optical amplifiers and convert the combined optical signal into an electrical signal; and a filter unit configured to filter the electrical signal passing through the photodetector, wherein the electrical signal obtained through the photodetector is compared with the electrical signal obtained by the photomixer, and phase noise having the same frequency is removed.
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公开(公告)号:US09784661B2
公开(公告)日:2017-10-10
申请号:US15263419
申请日:2016-09-13
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Bahram Jalali , Eric Diebold , Brandon Buckley
CPC classification number: G01N15/1434 , G01N15/1459 , G01N15/1484 , G01N21/64 , G01N21/6428 , G01N21/6458 , G01N21/6486 , G01N33/537 , G01N2015/1006 , G01N2015/1477 , G01N2021/6421 , G01N2201/067
Abstract: An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector.
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公开(公告)号:US20170235163A1
公开(公告)日:2017-08-17
申请号:US15584456
申请日:2017-05-02
Applicant: Honeywell International Inc.
Inventor: James Goeders , Matthew Edward Lewis Jungwirth
CPC classification number: G02F1/0115 , G01N21/645 , G01N2021/6484 , G01N2201/067 , G02F1/035 , G02F1/11 , G02F1/113 , G02F1/125 , G06N99/002 , H01J49/0018 , H01J49/424 , H01S3/0085
Abstract: Preparation cell systems and methods are described herein. One example of a system for a preparation cell includes a laser coupled to a fiber bundle comprising a plurality of fibers, a preparation cell to prepare a state of laser light received by the fiber bundle, and an exiting fiber bundle coupled to the preparation cell.
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