A METHOD OF CALIBRATING A MASS SPECTROMETER
    2.
    发明公开

    公开(公告)号:US20230386811A1

    公开(公告)日:2023-11-30

    申请号:US18032702

    申请日:2021-10-21

    CPC classification number: H01J49/0009 H01J49/0036 H01J49/42

    Abstract: We provide a method of assessing an acquired mass spectrum, the method including the steps of: obtaining a model isotope pattern for a chemical compound of known elemental composition, providing mass spectrum data obtained from a mass spectrometer in analysis of the chemical compound, and performing location matching by comparing the mass spectrum data to the isotope pattern to match a reference location in the isotope pattern with respective corresponding candidate locations in the mass spectrum data, the location matching including: determining a likelihood function over the mass spectrum data, representing the likelihood that each location in the mass spectrum data correctly corresponds to the reference location of the isotope pattern, determining a set of candidate locations each corresponding to a local maxima in the determined likelihood function, and at each candidate location, determining an associated error bar based on the curvature of the likelihood function at that location.

    ION GUIDE AND MASS SPECTROMETER USING SAME
    4.
    发明申请

    公开(公告)号:US20190148122A1

    公开(公告)日:2019-05-16

    申请号:US16228982

    申请日:2018-12-21

    CPC classification number: H01J49/063 H01J49/42

    Abstract: A first rod electrode set has a first center axis, into which ions and air current are introduced. A second rod electrode set has a second center axis at a distance from the first center axis, from which the ions are discharged. A power supply applies voltages to the first rod electrode set and the second rod electrode set. The first rod electrode set and the second rod electrode set have a region where the sets overlap each other in the longitudinal direction, and form a single multipole ion guide by being combined to each other in the region. Different offset DC voltages are applied to the first rod electrode set and the second rod electrode set, respectively, and a DC potential for moving the ions to the second rod electrode set in the region is formed, the ions having been guided by the first rod electrode set.

    Miniature quadrupole arrays using electron multiplication detectors

    公开(公告)号:US09863914B2

    公开(公告)日:2018-01-09

    申请号:US14808291

    申请日:2015-07-24

    Inventor: Said Boumsellek

    Abstract: A gas sensor includes a first chamber containing a plurality of evenly spaced rods having voltages applied thereto to cause gas ions in the first chamber to move in a direction from a first end of the first chamber to a second end of the first chamber and a second chamber coupled to the second end of the first chamber and having at least one ion detector, where ions pass from the first chamber to the second chamber through a plurality of channels between the first chamber and the second chamber and are detected by the at least one ion detector. The voltages applied to the rods may include a first voltage applied to a first subset of the rods and a second voltage applied to a second subset of the rods, each of first and second voltages containing a DC component and an AC component.

    Ion mobility separator with variable effective length
    9.
    发明授权
    Ion mobility separator with variable effective length 有权
    具有可变有效长度的离子迁移分离器

    公开(公告)号:US09552974B2

    公开(公告)日:2017-01-24

    申请号:US14751530

    申请日:2015-06-26

    CPC classification number: H01J49/36 G01N27/624 H01J49/06 H01J49/42 H01J49/426

    Abstract: An ion mobility separator or spectrometer is disclosed comprising an inner cylinder and an outer cylinder defining an annular volume through which ions are transmitted. Spiral electrodes a-f are arranged on a surface of the inner cylinder and/or on a surface of the outer cylinder. A first device is arranged and adapted to maintain a DC electric field and/or a pseudo-potential force which acts to urge ions from a first end of the ion mobility separator or spectrometer to a second end of the ion mobility separator or spectrometer. A second device is arranged and adapted to apply transient DC voltages to the one or more spiral electrodes in order to urge ions towards the first end of the ion mobility separator or spectrometer. The net effect is to extend the effective path length of the ion mobility separator.

    Abstract translation: 公开了一种离子迁移率分离器或光谱仪,其包括限定通过离子传播的环形体积的内圆筒和外圆筒。 螺旋电极a-f布置在内筒的表面上和/或外筒的表面上。 第一装置被布置和适于维持DC电场和/或伪电势力,其用于将离子从离子迁移率分离器或光谱仪的第一端推动到离子迁移率分离器或光谱仪的第二端。 第二装置被布置并适于将瞬态DC电压施加到一个或多个螺旋电极,以便促使离子朝向离子迁移率分离器或光谱仪的第一端。 净效应是延长离子迁移率分离器的有效路径长度。

    SYSTEM FOR RECORDING SPATIAL AND TEMPORAL PROPERTIES OF IONS EMITTED FROM A QUADRUPOLE MASS FILTER
    10.
    发明申请
    SYSTEM FOR RECORDING SPATIAL AND TEMPORAL PROPERTIES OF IONS EMITTED FROM A QUADRUPOLE MASS FILTER 有权
    用于记录从四重质量过滤器发射的离子的空间和时间性质的系统

    公开(公告)号:US20160217990A1

    公开(公告)日:2016-07-28

    申请号:US15088406

    申请日:2016-04-01

    Abstract: An ion detection system for a detecting a quantity of ions exiting from a mass analyzer of a mass spectrometer comprises: (a) photon generating means configured to receive the quantity of ions and to generate a quantity of photons that is proportional to the quantity of ions; (b) a linear array of photo-detectors configured along a line for detecting a variation of a portion of the quantity of generated photons along the line; and (c) an optical system for directing the portion of the quantity of photons from the photon generating means to the linear array of photo-detectors comprising: (c1) a first cylindrical lens having a first lens axis disposed parallel to the line; (c2) a second cylindrical lens or rod lens having a second lens axis disposed parallel to the line; and a doublet lens.

    Abstract translation: 用于检测从质谱仪的质量分析器离开的离子的量的离子检测系统包括:(a)光子产生装置,被配置为接收离子的量并产生与离子量成比例的一定量的光子 ; (b)沿着一条线构成的光电检测器的线性阵列,用于检测沿线产生的光子的一部分的变化; (c)用于将来自光子发生装置的光子量的一部分引导到光电检测器的线性阵列的光学系统,包括:(c1)具有平行于该线设置的第一透镜轴的第一柱面透镜; (c2)具有平行于所述线布置的第二透镜轴的第二柱面透镜或棒状透镜; 和双头透镜。

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