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11.发明公开성게의 건조분말, 이의 극성용매 가용 추출물 및 극성용매 불용성 잔사를 함유하는 간 해독 및 항산화 활성을 나타내는 조성물 失效包含干粉，极性溶剂提取物和作为活性成分显示肝脏脱氧和抗氧化活性的硫酸钠不溶性残留物的组合物
公开(公告)号：KR1020110001251A
公开(公告)日：2011-01-06
申请号：KR1020090058709
申请日：2009-06-30
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/616 , A23L33/00 , A23L17/20
CPC classification number: A61K35/616 , A23L17/20 , A23L33/00
Abstract: PURPOSE: A composition containing sea urchin extract with detoxification and antioxidation is provided. CONSTITUTION: A pharmaceutical composition for preventing and treating liver diseases contains dried powder of sea urchin, polar solvent soluble extract or polar solvent insoluble residue of the dried powder as an active ingredient. The sea urchin includes Anthocidaris crassispina, Hemicentrotus pulcherrimus, Pseudocentrotus depressus or Strongylocentrotus internmedius. The sea urchin includes eggs, intestine or shell. The polar solvent soluble extract contains an extract obtained using water, low alcohol or mixture solvent thereof.
Abstract translation: 目的：提供含有解毒和抗氧化作用的海胆提取物的组合物。 构成：用于预防和治疗肝脏疾病的药物组合物含有海胆干燥粉末，极性溶剂可溶性提取物或干粉末的极性溶剂不溶残留物作为活性成分。 海胆包括Ant includes ina ina，，，，，，，，，。。。。。。。。。。。。。。。。。。。 海胆包括鸡蛋，肠或壳。 极性溶剂可溶性提取物含有使用水，低级醇或其混合溶剂获得的提取物。
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13.发明公开양미리 분획 건조 분말 또는 그 추출물을 유효성분으로함유하는 통증질환의 예방 및 치료용 조성물 无效包含干燥粉末的砂糖（HYPOPTYCHUS DYBOWSKII）的组合物或其提取物，用于预防和治疗疼痛疾病
公开(公告)号：KR1020100006605A
公开(公告)日：2010-01-21
申请号：KR1020080066789
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing dried powder of sand lance fraction or its extract is provided to suppress pain using an animal model by inducing acetic acid pain test, heat plate and tail flick test. CONSTITUTION: A pharmaceutical composition for preventing and treating pain contains dried powder or its extract of sand lance fraction as an active ingredient. The extract of sand lance fraction is obtained by heating the sand lance fraction at 60°C-150°C for 12 to 48 hours. The pain is the headache, toothache, backache, burn ache, neuralgia, period pains or arthralgia. The pharmaceutical composition contains 0.1-50 weight% of the dried powder or its extract based on the total weight.
Abstract translation: 目的：提供一种含有喷沙部分或其提取物的干粉的组合物，通过诱导乙酸疼痛试验，加热板和尾巴轻弹试验，通过动物模型抑制疼痛。 构成：用于预防和治疗疼痛的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 通过在60℃-150℃下加热沙枪级分12至48小时获得沙枪分数的提取物。 疼痛是头痛，牙痛，背痛，疼痛，神经痛，周期痛或关节痛。 该药物组合物含有0.1-50重量％的干燥粉末或其提取物，基于总重量。
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公开(公告)号：KR1020100006599A
公开(公告)日：2010-01-21
申请号：KR1020080066783
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing dried powder and extract of chub mackerel fraction is provided to reduce total cholesterol and blood triglyceride content. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of dried powder or extract of chub mackerel fraction as an active ingredient. The fraction of the chub mackerel is head, cartilage, shell, muscle, eye, gill, total body of the fish. A method for preparing the dried powder of chub mackerel fraction comprises: a step of washing and removing foreign material and salt from the chub mackerel; and a step of cutting head, cartilage, shell, muscle, eye, gill, and total body. The extract is isolated using water, alcohol and spirit extract solvent.
Abstract translation: 目的：提供含有干粉的组合物和鲭鱼and提取物，以降低总胆固醇和血甘油三酯含量。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的干燥粉末或作为活性成分的鲭鱼片提取物。 小鲭鱼的分数是头，软骨，壳，肌肉，眼睛，鳃，鱼的全身。 一种制备鲭鱼m the干燥粉末的方法，包括：从鲭鱼鲭鱼中洗涤除去异物和盐的步骤; 并切割头，软骨，壳，肌肉，眼睛，鳃和全身的一个步骤。 使用水，酒精和精油提取物溶剂分离提取物。
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公开(公告)号：KR1020090105984A
公开(公告)日：2009-10-08
申请号：KR1020080031422
申请日：2008-04-04
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A method for manufacturing collagen isolated from the skin of bigeye tuna is provided to produce high quality of collagen with high solubility and emulsion stability. CONSTITUTION: A method for manufacturing collagen isolated from the skin of bigeye tuna comprises: a step for washing the skin of the bigeye tuna which is stored at -30 °C to -100 °C; a step for treating the skin with 0.05 ~ 10.0 %(w/v) of alkali solution; a step for washing and neutralizing with distilled water; a step for adding 0.05 ~ 10.0 N of acid to the skin, then stirring and extracting; a step for separating extracted liquid and residue using a centrifuge; and a step for drying to obtain acid soluble collagen (AC); a step for adding 0.5 ~ 5.0 N of acid; a step for adding 0.5 ~ 10% of pepsin and stirring and hydrolyzing for 1 to 60 hours; a step for separating extract liquid and residue using a filter; a step for adding NaCl to adjust the concentration to 1-10 % and neutralizing precipitates; and a step for freeze-drying to obtain a pepsin soluble collagen (PC).
Abstract translation: 目的：提供从大眼金枪鱼皮肤分离的胶原蛋白的制造方法，以生产高质量的胶原蛋白，具有高溶解性和乳液稳定性。 构成：从大眼金枪鱼皮肤分离的胶原蛋白的制造方法，其特征在于，包括：在-30℃-100℃保存的大眼金枪鱼皮肤的洗涤步骤; 用0.05〜10.0％（w / v）碱溶液处理皮肤的步骤; 用蒸馏水洗涤和中和的步骤; 向皮肤中加入0.05〜10.0N的酸，然后搅拌和提取; 使用离心机分离提取液和残渣的步骤; 和干燥以获得酸溶性胶原（AC）的步骤; 添加0.5〜5.0 N酸的步骤; 加入0.5〜10％胃蛋白酶，搅拌水解1〜60小时; 使用过滤器分离提取液和残渣的步骤; 添加NaCl以将浓度调节至1-10％并中和沉淀的步骤; 和冷冻干燥步骤以获得胃蛋白酶可溶性胶原（PC）。
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Patent Agency Ranking
公开(公告)号：KR100911826B1
公开(公告)日：2009-08-12
申请号：KR1020060138279
申请日：2006-12-29
Applicant: 정순범 , 강릉원주대학교산학협력단
Abstract: 본 발명은 해양심층수를 이용하여 제조한 김치의 제조방법에 관한 것으로, 본 발명의 해양심층수를 이용하여 제조한 김치에 대하여 염도 측정, pH 측정, 산도 측정, TBA 값 측정, 미생물수 측정 및 관능평가를 실시한 결과, 저장성 및 품질이 우수하고, 동시에 인체에 필수적인 무기염류 및 미네랄을 섭취할 수 있는 이점이 있기 때문에 식품학적 가치를 향상시키므로 국민들의 건강증진에 기여할 수 있다.
해양심층수, 소금, 김치, 미생물, 신선도, 방부성, 제조방법.-
公开(公告)号：KR1020080094983A
公开(公告)日：2008-10-28
申请号：KR1020070039157
申请日：2007-04-23
Applicant: 강릉원주대학교산학협력단
Abstract: Cuttlebone powder or an extract thereof is provided to inhibit gastrointestinal ulcer, thereby being used as a pharmaceutical composition and a health functional food for preventing and treating gastrointestinal diseases. A method for preparing an extract of a cuttlebone comprises the steps of: (a) drying and crushing the cuttlebone to obtain cuttlebone powder; (b) after reacting the cuttlebone powder with about 1-30 times of water, an aqueous solution of NaOH or an aqueous solution of HCl at a temperature of 20-100 deg.C for about 1-24 hour(s), separating a reaction solution and remnants; and (c) after neutralizing and desalinating the reaction solution, concentrating and freeze-drying it. A pharmaceutical composition for preventing or treating gastrointestinal diseases comprises 0.1-50 wt.% of the cuttlebone powder or the extract thereof as an effective ingredient. A health functional food for preventing and improving the gastrointestinal diseases comprises the powder of cuttlebone or the extract thereof as an effective ingredient. The health functional food is in a form of a granule, a tablet, a capsule, a syrup or a drink.
Abstract translation: 提供乌龟粉或其提取物以抑制胃肠溃疡，从而用作药物组合物和用于预防和治疗胃肠道疾病的健康功能食品。 一种制备粉刺提取物的方法，包括以下步骤：（a）干燥并粉碎cut骨以获得粉碎粉末; （b）在将粉刺粉末与约1-30倍的水，NaOH水溶液或HCl水溶液在20-100℃的温度下反应约1-24小时后，分离 反应液和残留物; 和（c）中和和脱盐反应溶液后，浓缩并冷冻干燥。 用于预防或治疗胃肠道疾病的药物组合物包含0.1-50重量％的粉碎粉末或其提取物作为有效成分。 用于预防和改善胃肠道疾病的健康功能食品包括粉刺粉或其提取物作为有效成分。 健康功能食品是颗粒，片剂，胶囊，糖浆或饮料的形式。
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公开(公告)号：KR101182032B1
公开(公告)日：2012-09-11
申请号：KR1020090106644
申请日：2009-11-05
Applicant: 강릉원주대학교산학협력단
Abstract: 본 발명은 항산화 활성을 갖는 다시마 추출물을 유효성분으로 함유하는 산화적 스트레스 관련 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 상세하게는 본 발명의 다시마 추출물은 DPPH 라디칼 소거능 실험에서 강력한 자유 라디칼 소거 작용을 나타내는 바, 항산화 활성을 증진시킴을 확인한 바, 산화적 스트레스 관련의 예방 및 치료에 유용한 약학조성물 및 건강기능식품에 이용될 수 있다.
다시마, 산화적 스트레스 관련, 라디칼, 항산화-
19.发明授权다시마 정유 추출물 또는 이로부터 분리된 화합물을 유효성분으로 함유하는 항균 조성물 失效一种抗菌组合物，其包含从所述Kjellemaiella crassifolia的精油提取物和从其中分离的化合物
公开(公告)号：KR101142598B1
公开(公告)日：2012-05-03
申请号：KR1020090121687
申请日：2009-12-09
Applicant: 강릉원주대학교산학협력단
IPC: A61K36/03 , A61P31/04 , A61K31/352 , A23L1/30
CPC classification number: Y02A50/473
Abstract: 본 발명은 다시마(Kjellemaiella crassifolia) 추출물 또는 이로부터 분리된 화합물을 유효성분으로 함유하는 항균 조성물에 관한 것으로, 상세하게는 본 발명의 추출물 또는 이로부터 분리된 화합물은
에스케리치아 콜라이(Escherichia coli) ,
바실러스 서브틸리스(Bacillus subtilis) ,
칸디다 알비칸스(Candida albicans) ,
스트렙토코커스 뮤탄스(Streptococcus mutans) 및
스타필로코커스 아우레우스(Staphylococcus aureus) 에 대하여 항균 활성을 나타내므로, 세균성 감염 질환의 예방 및 치료에 유용한 약학조성물 및 건강기능식품에 이용될 수 있다.
다시마, 화합물, 세균성 감염-
公开(公告)号：KR1020120001130A
公开(公告)日：2012-01-04
申请号：KR1020100061780
申请日：2010-06-29
Applicant: 강릉원주대학교산학협력단
CPC classification number: A23L17/00 , A22C25/14 , A23L3/3472 , A23L27/105 , A23L27/14 , A23L27/40 , A23V2250/156
Abstract: PURPOSE: A producing method of flatfish sik-hae(flatfish fermented with grains) containing salt obtained from deep sea water is provided to control the breeding of salted food deterioration causative bacteria in the flatfish sik-hae. CONSTITUTION: A producing method of flatfish sik-hae(flatfish fermented with grains) containing salt obtained from deep sea water comprises the following steps: removing head, intestines, and tail from flatfish, and washing and cutting the flatfish; adding 5-20%(w/w) of salt obtained from the deep sea water for salting the flatfish in a low temperature aging chamber at 0-20 deg C for 1-60 hours, and washing the salted flatfish; removing the moisture from the flatfish, and mixing the flatfish with red pepper powder, minced garlic, ginger juice, and cooked millet before aging at 1-50 deg C for 1-30 days; and adding sugar, salt, and pickled radish slices to the aged flatfish, and aging the mixture at 1-50 deg C for 1 day.
Abstract translation: 目的：提供含有从深海水中获得的盐的鲽鱼（鲽鱼发酵的鲽鱼）的生产方法，以控制鲽鱼食盐劣化致病细菌的繁殖。 构成：从深海水中获得的含有盐的鲽鱼（鲽鱼发酵的鲽鱼）的生产方法包括以下步骤：从鲽鱼中去除头部，肠和尾部，并清洗和切割鲽鱼; 加入5-20％（w / w）从深海水中获得的盐，在0-20℃的低温老化室中将鲽鱼腌制1-60小时，并洗涤盐渍的鲽鱼; 从鲽鱼中除去水分，并将鲽鱼与红辣椒粉，切碎的大蒜，生姜汁和煮熟的小米混合，然后在1-50℃老化1-30天; 并向老年鲽鱼中加入糖，盐和腌萝卜片，并将混合物在1-50℃老化1天。
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