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公开(公告)号：KR1020140064496A
公开(公告)日：2014-05-28
申请号：KR1020120131896
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
CPC classification number: A61K38/30 , A61K35/20 , B01D15/34 , B01D15/363 , Y10S514/909
Abstract: A method for separating insulin-like growth factor 1 (IGF-1) from mammalian milk of the present invention comprises the steps of: a) separating the mammalian milk into whey and casein; b) recovering fractions containing a large amount of IGF-1; c) separating the fractions containing a large amount of materials corresponding to a molecular weight of the IGF-1 by using ion exchange chromatography; d) separating the fractions containing a large amount of IGF-1 by using gel filtration chromatography; and e) recovering the fractions with 7000-13000 Da or less by passing the fractions containing a large amount of the IGF-1 through a membrane with 7000-13000 Da, and then recovering the IGF-1 by concentrating using a membrane with 700-1300 Da.
Abstract translation: 从本发明的哺乳动物乳中分离胰岛素样生长因子1（IGF-1）的方法包括以下步骤：a）将哺乳动物乳分离成乳清和酪蛋白; b）回收含有大量IGF-1的级分; c）使用离子交换色谱法分离含有大量相应于IGF-1分子量的材料; d）使用凝胶过滤层析分离含有大量IGF-1的级分; 和e）通过使含有大量IGF-1的级分通过具有7000-13000Da的膜的7000-13000Da或更低的级分回收级分，然后通过使用具有700-1000Da的膜浓缩来回收IGF-1， 1300 Da
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公开(公告)号：KR1020130142462A
公开(公告)日：2013-12-30
申请号：KR1020120065700
申请日：2012-06-19
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/342 , A61P25/28 , A61P25/16
Abstract: Provided is a composition for preventing or treating menopausal brain disorders which includes Adenophora triphylla var. japonica extract as an active constituent. The composition of the present invention can be usually used as a pharmaceutical composition or a health supplement composition for improving the recognition ability in menopausal women because the composition has recognition ability in menopausal animal models. [Reference numerals] (AA) OVA + Adenophora triphylla var. japonica
Abstract translation: 提供一种用于预防或治疗绝经性脑疾病的组合物，其包括Adenophora triphylla var。 粳稻提取物作为活性成分。 本发明的组合物通常可以用作药物组合物或健康补充剂组合物，用于提高绝经妇女的识别能力，因为该组合物在绝经动物模型中具有识别能力。 （AA）OVA + Adenophora triphylla var。 粳稻
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公开(公告)号：KR1020130102194A
公开(公告)日：2013-09-17
申请号：KR1020120023232
申请日：2012-03-07
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/899 , A61K8/97 , A61P17/00 , A61Q19/02
Abstract: PURPOSE: An Oryza Sativa L. extract is provided to suppress the expression of a gene of melanogenesis-related enzyme and to directly suppress melanogenesis, thereby showing superior whitening effects. CONSTITUTION: An ethanol extract of Oryza Sativa L. has whitening effect. Oryza Sativa L. is produced by artificial crossbreeding between Oryza sativa cv. Heugnambyeo and Milyang 153. The ethanol extract is prepared using 75-85 % ethanol. The ethanol extract suppresses melanogenesis and the expression of tyrosinase, TRP-1, and TRP-2 genes.
Abstract translation: 目的：提供一种水iva提取物，以抑制黑素生成相关酶基因的表达并直接抑制黑素生成，从而显示出优异的美白效果。 构成：水稻的乙醇提取物具有美白效果。 水稻（Oryza Sativa L.）是通过人工杂交在水稻（Oryza sativa cv。 Heugnambyeo和Milyang 153.乙醇提取物使用75-85％乙醇制备。 乙醇提取物抑制黑素生成和酪氨酸酶，TRP-1和TRP-2基因的表达。
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公开(公告)号：KR1020130037788A
公开(公告)日：2013-04-17
申请号：KR1020110102218
申请日：2011-10-07
Applicant: 대한민국(농촌진흥청장)
CPC classification number: A61K36/73 , A23V2200/328 , A61K2236/331
Abstract: PURPOSE: A blood glucose reducing agent for menopausal women is provided to enhance an adiponectin concentration in blood and to treat insulin resistance. CONSTITUTION: A blood glucose reducing agent for menopausal women contains an Agrimonia pilosa Ledeb extract. The extract is a water extract of Agrimonia pilosa Ledeb, and enhances an adiponectin concentration in blood. The blood glucose reducing agent is healthy food or a pharmaceutical formulation. [Reference numerals] (AA) Example 1; (BB) Example 2; (CC) Example 3; (DD) Example 4;
Abstract translation: 目的：提供更年期妇女的血糖降低剂，以增强血液中的脂联素浓度和治疗胰岛素抵抗。 构成：绝经妇女的血糖降低剂含有Agrimonia pilosa Ledeb提取物。 提取物是Agrimonia pilosa Ledeb的水提取物，并且增加血液中的脂联素浓度。 血糖降低剂是健康食品或药物制剂。 （标号）（AA）实施例1; （BB）实施例2; （CC）实施例3; （DD）实施例4
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Patent Agency Ranking
公开(公告)号：KR1020120058255A
公开(公告)日：2012-06-07
申请号：KR1020100119954
申请日：2010-11-29
Applicant: 대한민국(농촌진흥청장)
CPC classification number: A23L33/105 , A23L19/00 , A23V2002/00 , A23V2200/222 , A23V2200/30
Abstract: PURPOSE: A nanocube liquid crystalline phase composition containing a rubus coreanus extract, and a producing method thereof are provided to improve the bio-membrane permeability of water-soluble and oil-soluble effective components of the rubus coreanus extract inside the body of users. CONSTITUTION: A producing method of a nanocube liquid crystalline phase composition containing a rubus coreanus extract comprises the following steps: dissolving mono-olein in one solvent selected from chloroform, methanol, and ethanol, and mixing an emulsifier to obtain a melt solution; adding water to the rubus coreanus to obtain an aqueous rubus coreanus extract solution; and adding the aqueous rubus coreanus extract solution into the melt solution in a ratio of 1:1-20(v/v), and homogenizing the mixture. The nanocube liquid crystalline phase composition contains 1-50wt% of rubus coreanus extract. The emulsifier is selected from polysorbates, sodium lauryl sulfate, sorbitan fatty acid ester, lecithin, enzymolysis lecithin, glycerin fatty acid ester, saccharose fatty acid ester, propylene glycol fatty acid ester, or polaxamers.
Abstract translation: 目的：提供一种含有芦荟提取物的纳米管液晶相组合物及其制造方法，以提高使用者体内的芦荟提取物的水溶性和油溶性有效成分的生物膜渗透性。 构成：含有木薯提取物的纳米管液晶相组合物的制造方法包括以下步骤：将单油酸酯溶解在选自氯仿，甲醇和乙醇的一种溶剂中，并混合乳化剂以获得熔融溶液; 将水加入到芦荟中以获得含水木糖提取物溶液; 并以1：1-20（v / v）的比例将水溶液提取物溶液加入到熔体溶液中，并均化混合物。 纳米管液晶相组合物含有1-50重量％的木薯提取物。 乳化剂选自聚山梨醇酯，十二烷基硫酸钠，脱水山梨糖醇脂肪酸酯，卵磷脂，酶解卵磷脂，甘油脂肪酸酯，蔗糖脂肪酸酯，丙二醇脂肪酸酯或polaxamers。
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公开(公告)号：KR101557064B1
公开(公告)日：2015-10-08
申请号：KR1020120023232
申请日：2012-03-07
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/899 , A61K8/97 , A61P17/00 , A61Q19/02
Abstract: 본발명은미백활성이있는신토흑미(Oryza Sativa L.) 에탄올추출물을제공한다. 본발명의신토흑미에탄올추출물은멜라닌합성에관여하는효소의유전자발현을억제하여직접적으로멜라닌합성을저해함으로써확실한미백효과를가져다줄수 있으며, 미백화장품조성물또는건강기능보조식품으로활용이가능하다.
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公开(公告)号：KR101549145B1
公开(公告)日：2015-09-01
申请号：KR1020130139871
申请日：2013-11-18
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은건조꽃잎이포함된꿀의제조방법에관한것으로서, 더욱상세하게는다공질조직사이에공기가들어차있는건조꽃잎을꿀에첨가하여혼합시건조꽃잎이꿀의표면에뜨지않고고르게분포되는꿀을제조할수 있고, 건조꽃잎의영양성분이꿀과잘 조화되어영양및 맛이우수한건강기능식품을제공할수 있다.
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公开(公告)号：KR1020150057158A
公开(公告)日：2015-05-28
申请号：KR1020130140134
申请日：2013-11-18
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은대맥장유래리조푸스오리제 () DM07 (KACC 93187P) 균주및 이를이용한발효식품의제조방법에관한것이다.
Abstract translation: 本发明涉及源自Daemacjang（黑豆酱）的米曲霉DM07（KACC 93187P）菌株及使用其的发酵食品的制造方法。 在本发明中，提供了用于产生与发酵相关的酶并且几乎不产生黄曲霉毒素B1的发酵菌株。
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公开(公告)号：KR1020150057054A
公开(公告)日：2015-05-28
申请号：KR1020130139871
申请日：2013-11-18
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은건조꽃잎이포함된꿀의제조방법에관한것으로서, 더욱상세하게는다공질조직사이에공기가들어차있는건조꽃잎을꿀에첨가하여혼합시건조꽃잎이꿀의표면에뜨지않고고르게분포되는꿀을제조할수 있고, 건조꽃잎의영양성분이꿀과잘 조화되어영양및 맛이우수한건강기능식품을제공할수 있다.
Abstract translation: 本发明涉及一种制备含有干燥花瓣的蜂蜜的方法。 更具体地，该方法包括以下步骤：将含有多孔组织中的空气的干燥花瓣加入到蜂蜜中并将踏板与蜂蜜混合。 因此，干燥的踏板可以均匀分布在蜂蜜中，而不会漂浮在蜂蜜的表面上。 干花瓣的营养成分也可以在蜂蜜中混合，以提供极好的口味和营养成分的膳食补充剂。
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