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公开(公告)号：EP1097944A4
公开(公告)日：2004-03-31
申请号：EP99928210
申请日：1999-07-06
Applicant: FUSO PHARMACEUTICAL IND
Inventor： YAMAMOTO HIROSHI , TSUJIKAWA KAZUTAKE , UCHINO YUKIKO
CPC classification number: C07K16/40 , G01N33/573 , G01N2333/916
Abstract: An antibody specific to intracellular domains of at least two protein tyrosine phosphatases; a process for preparing the same; and cells producing the above antibody. This antibody, which has specificities to intracellular domains of both of phosphatase subunits LAR and CD45, is useful in analyzing and quantitating PTPs, identifying and detecting a novel PTP, acquiring a novel phosphatase by cloning, etc., as well as developing a diagnostic method useful in insulin resistance and NIDDM, preventing, treating (curing, etc.) and diagnosing various symptoms of syndrome X based on insulin resistance, and preventing and diagnosing the onset of arteriosclerosis and heart diseases.
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公开(公告)号：EP1258251A4
公开(公告)日：2003-04-09
申请号：EP01904557
申请日：2001-02-20
Applicant: FUSO PHARMACEUTICAL IND
Inventor： ARAKI HIROMASA , KAWABATA ATSUFUMI , KURODA RYOTARO , KAKEHI KAZUAKI , TANAKA SHUICHI , KAWAI KENZO , NISHIMURA SACHIYO , NISHIKAWA HIROYUKI
IPC: A61K9/00 , A61K38/00 , A61K38/08 , A61K38/17 , A61K38/46 , A61K38/55 , A61K45/00 , A61K45/06 , A61P1/04 , A61P1/12 , A61K38/48
CPC classification number: A61K38/08 , A61K38/06 , A61K38/482 , A61K38/4826 , A61K2300/00
Abstract: The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve the problems which was difficult to be solved by the side effect previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.
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23.发明公开
公开(公告)号：EP1108780A4
公开(公告)日：2003-01-02
申请号：EP99929745
申请日：1999-07-08
Applicant: FUSO PHARMACEUTICAL IND
Inventor： YAMADA OSAMU , YOSHIDA HIROSHI , ZHANG JING
Abstract: A nucleic acid sequence for potentiating the expression of a useful gene which contains a sequence carried by the 5'-nontranslational region, its fragment or its variant and is capable of potentiating the expression of a gene to thereby elevate the yield of the gene product; a vector containing the above nucleic acid sequence; host cells transformed or transfected by the above vector; a process for producing a useful gene product by using the vector; and a method for potentiating the expression of a useful gene by using the vector. Moreover, the above-mentioned sequence is useful in screening an initiation factor of interaction with IRES or IRES-dependency, treating diseases caused by the cap-dependent mRNA translation or a decrease in the IRES activity, or in diagnosing the severity of hepatitis C.
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公开(公告)号：EP1164199A4
公开(公告)日：2002-05-08
申请号：EP00908024
申请日：2000-03-13
Applicant: FUSO PHARMACEUTICAL IND
Inventor： SUGIYAMA ATSUSHI
IPC: C12Q1/06 , C12Q1/00 , C12Q1/26 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/527 , C12Q1/533
CPC classification number: G01N33/5308 , C12Q1/008 , C12Q1/527 , G01N33/573
Abstract: A method for quickly assaying the cAMP content or the adenylate cyclase activity in a biological sample containing endogenous non-cyclic adenine nucleotides without resort to any radioactive reagents. More particularly, a method for assaying the cAMP content or the adenylate cyclase activity in a biological sample containing endogenous non-cyclic adenine nucleotides selected from the group consisting of cAMP formed by endogenous adenylate cyclase, ATP, AMP, ADP and mixtures thereof which comprises: (1) adding efficacious amounts of apyrase, adenosine deaminase and alkaline phosphatase to the above sample to thereby enzymatically remove the endogenous non-cyclic adenine nucleotides other than cAMP and glycose-6-phosphate therefrom; (2) enzymatically converting cAMP into AMP; and (3) thus quantitating AMP without resort to any radioactive substances; and a kit for performing this method.
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公开(公告)号：EP0846701A4
公开(公告)日：2001-02-07
申请号：EP95933617
申请日：1995-10-02
Applicant: FUSO PHARMACEUTICAL IND
Inventor： WAKAMIYA NOBUTAKA
Abstract: A recombinant conglutinin containing a collagen region comprising six amino acid residues containing two amino acid sequences Gly-Xaa-Xaa (SEQ ID NO:3, Xaa representing a protein-constituting amino acid residue), a neck region of natural conglutinin and a sugar-chain recognition region of natural conglutinin, having an antiviral activity (neutralizing activity), and being expected to be applicable for medicinal uses.
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Patent Agency Ranking
公开(公告)号：EP0725149A4
公开(公告)日：1999-08-18
申请号：EP95907490
申请日：1993-08-10
Applicant: FUSO PHARMACEUTICAL IND
Inventor： MATSUHISA AKIO , SHIBA KIYOTAKA , MIKAWA YOSHIKAZU , KISHI YUICHIRO
CPC classification number: C12Q1/6816 , C12Q1/6813
Abstract: A method of detecting a nucleic acid which comprises bringing a solid carrier suspected to carry or contain a nucleic acid into contact with a polyamine containing, bound thereto, a label capable of generating a detectable signal or a precursor thereof to thereby form a complex between a nucleic acid, if any, and the polyamine, removing the polyamine which has not formed any complex before or after the conversion of the precursor, if used, into the label, and detecting the label.
Abstract translation: 一种检测核酸的方法，其包括将怀疑携带或含有核酸的固体载体与含有与其结合的多胺接触能够产生可检测信号的标记或其前体的标记，从而在 核酸（如果有的话）和多胺，除去在前体转化之前或之后没有形成任何复合物的多胺（如果使用的话）到标签中，并检测标签。
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27.发明公开NOVEL SODIUM DIACETATE CRYSTAL AND SOLID DIALYSIS PREPARATION COMPRISING SAID CRYSTAL 有权NEUARTIGER NATRIUMDIACETATKRISTALL UND FESTESDIALYSEPRÄPARATMIT DIESEM KRISTALL
公开(公告)号：EP3070075A4
公开(公告)日：2017-10-04
申请号：EP14861241
申请日：2014-11-12
Applicant: FUSO PHARMACEUTICAL IND
Inventor： SHIMAMURA HIDEO , MURAKAMI TADATAKA , KURATA YASUNORI , KATO AYAKA
CPC classification number: C07C53/10 , A61K9/1605 , A61K9/1617 , A61K9/1623 , A61K33/20 , A61K45/06 , A61M1/1654 , C07C51/347
Abstract: A novel highly stable sodium diacetate crystal, in which the volatilization of acetic acid can be suppressed for a long period. More specifically, a sodium diacetate crystal having a median diameter in the range of 300 to 3000 µm.
Abstract translation: 一种新型高稳定性的二乙酸钠晶体，其中醋酸的挥发可长时间抑制。 更具体地说，具有中值直径在300至3000μm范围内的二乙酸钠晶体。
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公开(公告)号：EP3042689A4
公开(公告)日：2017-05-10
申请号：EP14840866
申请日：2014-08-27
Applicant: TAISEI KAKO CO , FUSO PHARMACEUTICAL IND , 3-D MATRIX LTD
Inventor： HORITA TAIJI , MATSUMOTO IPPEI , SONOYAMA TOMOYUKI , NISHIOKA FUKUMITSU , TANIOKA SHOUJIROU , NOHARA MASAHIRO , TAKANO KIYOSHI
CPC classification number: A61M35/003 , A61M5/345 , A61M5/347 , A61M2005/3104
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公开(公告)号：EP3031427A4
公开(公告)日：2017-01-25
申请号：EP14833942
申请日：2014-08-06
Applicant: FUSO PHARMACEUTICAL IND , NEXTIER
Inventor： SHINZATO TORU , KITAHARA YUZURU
CPC classification number: A61F5/56
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公开(公告)号：EP2597093A4
公开(公告)日：2013-12-04
申请号：EP11809488
申请日：2011-05-17
Applicant: FUSO PHARMACEUTICAL IND
Inventor： OHISHI YOSHITAKA , TODA TAKAO , TAKEDA SEIICHI
IPC: C07D417/04 , A61K31/427 , A61P35/00
CPC classification number: C07D417/04
Abstract: Provided is a novel compound having an effective anti-cancer activity. The novel compound according to the present invention includes a compound represented by formula (I): [wherein R 1 represents an alkoxyalkyl group having 2 to 6 carbon atoms] or a pharmaceutically acceptable salt thereof.
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