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公开(公告)号：NO996579D0
公开(公告)日：1999-12-30
申请号：NO996579
申请日：1999-12-30
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07C
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
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公开(公告)号：ZA9800018B
公开(公告)日：1998-07-02
申请号：ZA9800018
申请日：1998-01-02
Applicant: ABBOTT LAB
Inventor： DAVIDSEN STEVEN K , SHEPPARD GEORGE S , XU LIANHONG , CURTIN MICHAEL L , WADA CAROL K , FLORJANCIC ALAN SCOTT , GIESLER JAMIE R , GUO YAN , MICHAELIDES MICHAEL R , HOLMS JAMES H
IPC: A61K31/165 , A61K31/197 , A61K31/381 , A61K31/404 , A61K31/4184 , A61K31/421 , A61K31/426 , A61K31/4406 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C233/32 , C07C259/06 , C07D207/32 , C07D207/323 , C07D207/335 , C07D209/14 , C07D213/50 , C07D235/14 , C07D263/32 , C07D277/24 , C07D277/28 , C07D277/30 , C07D333/22 , C07F , A61K , C07C
CPC classification number: C07D207/335 , C07B2200/07 , C07C233/32 , C07C259/06 , C07C2601/14 , C07D209/14 , C07D213/50 , C07D235/14 , C07D263/32 , C07D277/28 , C07D333/22
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公开(公告)号：CY1111599T1
公开(公告)日：2015-10-07
申请号：CY091100278
申请日：2009-03-12
Applicant: ABBOTT LAB
Inventor： BETSCHMANN PATRICK , BURCHAT ANDREW F , CALDERWOOD DAVID J , CURTIN MICHAEL L , DAVIDSEN STEVEN K , DAVIS HEATHER M , FREY ROBIN R , HEYMAN HOWARD R , HIRST GAVIN C , HRNCIAR PETER , MICHAELIDES MICHAEL R , MUCKEY MELANIE A , RAFFERTY PAUL , WADA CAROL K
IPC: C07D495/04 , A61K31/4355 , A61K31/4365 , A61P35/00 , C07D491/04 , C07D498/04
Abstract: Ενώσειςπουέχουντονχημικότύπο: (I), είναιχρήσιμεςγιατηναναστολήκινασώντυροσίνηςπρωτεΐνης. Στηνπαρούσαεφεύρεσηαποκαλύπτονταικαιδημοσιοποιούνταιωςαναφοράεπίσηςμέθοδοιγιατηνπαρασκευήτωνενώσεων, τωνσυνθέσεωνπουπεριέχουντιςενώσεις, καιτωνμεθόδωναγωγήςχρησιμοποιώνταςτιςενώσεις.
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公开(公告)号：NZ544712A
公开(公告)日：2009-09-25
申请号：NZ54471204
申请日：2004-07-26
Applicant: ABBOTT LAB
Inventor： BETSCHMANN PATRICK , BURCHAT ANDREW F , CALDERWOOD DAVID J , CURTIN MICHAEL L , DAVIDSEN STEVEN K , DAVIS HEATHER M , FREY ROBIN R , HEYMAN HOWARD R , HIRST GAVIN C , HRNCIAR PETER , MICHAELIDES MICHAEL R , MUCKEY MELANIE A , RAFFERTY PAUL , WADA CAROL K
IPC: C07D495/04 , A61K31/4355 , A61K31/4365 , A61P35/00 , C07D491/04 , C07D498/04
Abstract: Disclosed are compounds of formula (I) wherein: X is S; Z is C; R1 and R3 are as described in the specification; and R2 is hydrogen or alkyl. Compounds of the type disclosed are tyrosine kinase inhibitors useful in the treatment of cancer.
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公开(公告)号：BRPI0412894A
公开(公告)日：2006-10-03
申请号：BRPI0412894
申请日：2004-07-26
Applicant: ABBOTT LAB
Inventor： BETSCHMANN PATRICK , BURCHAT ANDREW F , CALDERWOOD DAVID J , CURTIN MICHAEL L , DAVIDSEN STEVEN K , DAVIS HEATHER M , FREY ROBIN R , HEYMAN HOWARD R , HIRST GAVIN C , HRNCIAR PETER , MICHAELIDES MICHAEL R , MUCKEY MELANIE A , RAFFERTY PAUL , WADA CAROL K
IPC: A61P35/00 , C07D491/04 , C07D495/04 , C07D498/04 , A61K31/4355 , A61K31/4365
Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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Patent Agency Ranking
公开(公告)号：MXPA06000919A
公开(公告)日：2006-05-04
申请号：MXPA06000919
申请日：2004-07-26
Applicant: ABBOTT LAB
Inventor： WADA CAROL K
IPC: A61K31/4355 , A61K31/4365 , A61P35/00 , C07D491/04 , C07D495/04 , C07D498/04
Abstract: Los compuestos que tienen la Formula (I): (ver formula (I)) son utiles para inhibir las quinasas de proteina tirosina. La presente invencion tambien da a conocer metodos para hacer los compuestos, composiciones que contienen a los compuestos, y metodos de tratamiento utilizando los compuestos.
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公开(公告)号：AU2004259765A1
公开(公告)日：2005-02-03
申请号：AU2004259765
申请日：2004-07-26
Applicant: ABBOTT LAB
Inventor： HRNCIAR PETER , DAVIS HEATHER M , BURCHAT ANDREW F , WADA CAROL K , HEYMAN HOWARD R , HIRST GAVIN C , FREY ROBIN R , RAFFERTY PAUL , CALDERWOOD DAVID J , CURTIN MICHAEL L , MUCKEY MELANIE A , DAVIDSEN STEVEN K , MICHAELIDES MICHAEL R , BETSCHMANN PATRICK
IPC: C07D495/04 , A61K31/4355 , A61K31/4365 , A61P35/00 , C07D491/04 , C07D498/04
Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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公开(公告)号：DE69809924T2
公开(公告)日：2003-08-21
申请号：DE69809924
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07C259/00
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
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公开(公告)号：HU0002037A2
公开(公告)日：2001-05-28
申请号：HU0002037
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F JR , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
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公开(公告)号：CZ473099A3
公开(公告)日：2000-06-14
申请号：CZ473099
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F JR , FLORJANIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN ROBIN H , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: A61K31/16 , A61P19/02 , A61P35/00 , C07C259/00 , C07C259/04
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