-
1.发明申请
公开(公告)号：WO2007067781A3
公开(公告)日：2007-07-26
申请号：PCT/US2006047078
申请日：2006-12-08
Applicant: ABBOTT LAB , MICHAELIDES MICHAEL R , MCCLELLAN WILLIAM J , FREY ROBIN R , CURTIN MICHAEL L , STEINMAN DOUGLAS H , DAI YUJIA , HOLMS JAMES H
Inventor： MICHAELIDES MICHAEL R , MCCLELLAN WILLIAM J , FREY ROBIN R , CURTIN MICHAEL L , STEINMAN DOUGLAS H , DAI YUJIA , HOLMS JAMES H
IPC: C07D487/04 , A61K31/519 , A61P35/00 , C07D495/04
CPC classification number: C07F9/6561 , C07D487/04 , C07D495/04
Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating cancer using the compounds are disclosed.
Abstract translation: 公开了抑制蛋白激酶的化合物，含有化合物的组合物和使用该化合物治疗癌症的方法。
-
2.发明申请N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES 审中-公开作为基质金属蛋白酶抑制剂的N-羟基甲酰胺衍生物
公开(公告)号：WO9906361A3
公开(公告)日：1999-04-22
申请号：PCT/US9815486
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F JR , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , A61K31/16 , A61K31/415
CPC classification number: C07D207/404 , C07C311/05 , C07C311/18 , C07C317/28 , C07C323/47 , C07C323/62 , C07D207/408 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
Abstract translation: 具有式（I）的化合物是基质金属蛋白酶抑制剂。 还公开了抑制哺乳动物基质金属蛋白酶的基质金属蛋白酶抑制组合物和抑制基质金属蛋白酶的方法。
-
公开(公告)号：WO2005074603A2
公开(公告)日：2005-08-18
申请号：PCT/US2005003196
申请日：2005-02-03
Applicant: ABBOTT LAB , WISHART NEIL , FRIEDMAN MICHAEL , ARNOLD LEE D , YANG BRYANT , FIX-STENZEL SHANNON R , ERICSSON ANNA , MICHAELIDES MICHAEL R , QIAN XIAO-DONG , HOLMES JAMES H , STEINMAN DOUGLAS H , TIAN ZHENGPING , WITTENBERGER STEVEN J
Inventor： WISHART NEIL , FRIEDMAN MICHAEL , ARNOLD LEE D , YANG BRYANT , FIX-STENZEL SHANNON R , ERICSSON ANNA , MICHAELIDES MICHAEL R , QIAN XIAO-DONG , HOLMES JAMES H , STEINMAN DOUGLAS H , TIAN ZHENGPING , WITTENBERGER STEVEN J
IPC: C07D487/04
CPC classification number: C07D487/04
Abstract: A compound of Formula (I), wherein the substituents are as defined herein, which are useful as kinase inhibitors.
Abstract translation: 式（I）的化合物，其中取代基如本文所定义，其可用作激酶抑制剂。
-
公开(公告)号：EP0595924A4
公开(公告)日：1994-08-24
申请号：EP92915895
申请日：1992-07-14
Applicant: ABBOTT LAB
Inventor： SUMMERS JAMES B , DAVIDSEN STEVEN K , HOLMS JAMES H , PIREH DAISY , HEYMAN H ROBIN , MARTIN MICHAEL B , STEINMAN DOUGLAS H , SHEPPARD GEORGE S , CARRERA GEORGE M JR
IPC: A61K31/44 , A61K31/4406 , A61K49/00 , A61K49/06 , A61P1/04 , A61P7/02 , A61P7/06 , A61P9/02 , A61P11/06 , A61P17/06 , A61P29/00 , A61P37/06 , A61P37/08 , A61P43/00 , C07B47/00 , C07D213/69 , C07D487/04 , C07D498/04 , C07D513/04 , C07F5/00 , C07F13/00
CPC classification number: C07D487/04 , A61K49/06 , C07D213/69 , C07D513/04
-
公开(公告)号：EP0574494A4
公开(公告)日：1994-07-06
申请号：EP92906944
申请日：1992-02-14
Applicant: ABBOTT LAB
Inventor： SUMMERS JAMES B , SHEPPARD GEORGE S , PHILLIPS JAMES G , PIREH DAISY , STEINMAN DOUGLAS H , MAY PAUL D , GUINN DENISE E , HEYMAN H ROBIN , CARRERA GEORGE M JR , DAVIDSEN STEVEN K
IPC: A61K31/44 , A61K31/4427 , A61K31/4433 , A61P7/02 , A61P11/00 , A61P29/00 , C07D401/14 , C07D403/14 , C07D409/14 , C07D417/14
CPC classification number: C07D409/14 , C07D417/14
-
Patent Agency Ranking
公开(公告)号：EP1730148A4
公开(公告)日：2009-08-19
申请号：EP05722668
申请日：2005-02-03
Applicant: ABBOTT LAB
Inventor： WISHART NEIL , FRIEDMAN MICHAEL , ARNOLD LEE D , YANG BRYANT , FIX-STENZEL SHANNON R , ERICSSON ANNA , MICHAELIDES MICHAEL R , QIAN XIAO-DONG , HOLMES JAMES H , STEINMAN DOUGLAS H , TIAN ZHENGPING , WITTENBERGER STEVEN J
IPC: C07D487/04 , A61K31/381 , A61K31/519 , A61K31/5377 , C07D239/70 , C07D263/54 , C07D295/03 , C07D513/06
CPC classification number: C07D487/04
-
公开(公告)号：CA2358951C
公开(公告)日：2009-10-20
申请号：CA2358951
申请日：2000-01-27
Applicant: ABBOTT LAB
Inventor： STEINMAN DOUGLAS H , DAVIDSEN STEVEN K , DAI YUJIA , MICHAELIDES MICHAEL R , CURTIN MICHAEL L , HEYMAN HOWARD R , HOLMS JAMES H
IPC: C07D317/28 , A61K31/335 , A61K31/341 , A61K31/357 , A61K31/40 , A61K31/421 , A61P1/02 , A61P1/04 , A61P17/02 , A61P19/02 , A61P19/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D207/09 , C07D207/14 , C07D207/48 , C07D263/04 , C07D307/14
Abstract: Compounds having formula (I) are matric metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
-
公开(公告)号：DE69809924T2
公开(公告)日：2003-08-21
申请号：DE69809924
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07C259/00
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
-
公开(公告)号：DK0874808T3
公开(公告)日：2003-08-04
申请号：DK96940406
申请日：1996-11-13
Applicant: ABBOTT LAB
Inventor： FESIK STEPHEN W , SUMMERS JAMES B JR , DAVIDSEN STEVEN K , SHEPPARD GEORGE S , STEINMAN DOUGLAS H , CARRERA GEORGE M JR , FLORJANCIC ALAN , HOLMS JAMES H
IPC: A61P19/02 , A61K31/185 , A61K31/275 , A61P29/00 , A61P35/04 , A61P43/00 , C07C259/06 , C07C323/60 , A61K31/16
Abstract: Compounds of formula or a pharmaceutically acceptable salt thereof inhibit matrix metalloproteinases and TNF alpha secretion and are useful in the treatment of inflammatory disease states. Also disclosed are matrix metalloproteinases and TNF alpha secretion inhibiting compositions and a method for inhibiting matrix metalloproteinases and TNF alpha secretion.
-
公开(公告)号：HU0105477A2
公开(公告)日：2002-05-29
申请号：HU0105477
申请日：2000-01-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAI YUJIA , DAVIDSEN STEVEN K , HEYMAN HOWARD R , HOLMES JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H
IPC: A61K31/341 , A61K31/357 , A61K31/40 , A61K31/421 , A61P1/02 , A61P1/04 , A61P17/02 , A61P19/02 , A61P19/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D207/09 , C07D207/14 , C07D207/48 , C07D263/04 , C07D307/14 , C07D317/28
Abstract: Compounds having the formula are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
-
-
-
-
-
-
-
-
-
Search Results
83
records
(took 0.181 seconds)
