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公开(公告)号：HRP20130536T1
公开(公告)日：2013-07-31
申请号：HRP20130536
申请日：2013-06-12
Applicant: VERTEX PHARMA
Inventor： ZHANG BEILI , KRAWIEC MARIUSZ , BOTFIELD MARTYN , GROOTENHUIS PETER D J , VAN GOOR FREDRICK
IPC: C07D215/56 , A61K31/4704 , A61P1/00 , A61P11/00
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公开(公告)号：HK1161259A1
公开(公告)日：2012-08-24
申请号：HK12102075
申请日：2012-02-29
Applicant: VERTEX PHARMA
Inventor： BINCH HAYLEY , FANNING LEV T D , HURLEY DENNIS , SHETH URVI , SILINA ALINA , YANG XIAOQING , BOTFIELD MARTYN , GROOTENHUIS PETER D J , GOOR FREDRICK VAN , NUMA MEHDI MICHEL DJAMEL
IPC: C07D20060101 , A61K20060101 , A61P20060101
Abstract: The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
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公开(公告)号：MX2011004374A
公开(公告)日：2011-05-23
申请号：MX2011004374
申请日：2009-10-23
Applicant: VERTEX PHARMA
Inventor： GROOTENHUIS PETER D J , ZHANG BEILI , KRAWIEC MARIUSZ , BOTFIELD MARTYN , GOOR FREDRICK VAN
IPC: C07D215/56 , A61K31/4704 , A61P1/00 , A61P11/00
Abstract: La presente invención se refiere a formas en estado sólido sustancialmente cristalinas y libres de N-(4-7-azabiciclo[2,2,1]he ptan-7-il)-2-(trifluorometil)fenil)-4-oxo-5- (trifluorometil)-1,4- dihidroquinolin-3-carboxamida (Forma A), sus composiciones farmacéuticas y métodos de tratamiento con ellas.
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公开(公告)号：CA2741178A1
公开(公告)日：2010-04-29
申请号：CA2741178
申请日：2009-10-23
Applicant: VERTEX PHARMA
Inventor： ZHANG BEILI , KRAWIEC MARIUSZ , BOTFIELD MARTYN , GROOTENHUIS PETER D J , VAN GOOR FREDRICK
IPC: C07D215/56 , A61K31/4704 , A61P1/00 , A61P11/00
Abstract: The present invention relates to solid state forms, for example, crystalline forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, pharmaceutical compositions thereof, and methods therewith.
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公开(公告)号：CA2568405A1
公开(公告)日：2005-12-15
申请号：CA2568405
申请日：2005-05-27
Applicant: VERTEX PHARMA
Inventor： BOTFIELD MARTYN , RAMACHANDRAN RAVI , JAIN-PANDEY JUGNU , HARDING MATTHEW W
Abstract: The present invention is directed to methods for ameliorating reproductive disorders. More specifically, the present invention describes methods and compositions for using IL-17 in the treatment of various infertility-related defects.
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Patent Agency Ranking
公开(公告)号：MX373230B
公开(公告)日：2025-03-05
申请号：MX2018015847
申请日：2011-02-14
Applicant: VERTEX PHARMA
Inventor： GROSSI ALFREDO , YOUNG CHRISTOPHER , DINEHART KIRK , OVERHOFF KIRK , JACOBUS VERWIJS MARINUS , BOTFIELD MARTYN , HURTER PATRICIA , GROOTENHUIS PETER D J , ROWE WILLIAM
Abstract: La presente invención se refiere a composiciones farmacéuticas que comprenden una dispersión sólida de N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida, a métodos de producción de composiciones farmacéuticas de la presente invención y a métodos de administración de composiciones farmacéuticas de la presente invención.
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公开(公告)号：SI2464337T2
公开(公告)日：2024-08-30
申请号：SI201031871
申请日：2010-02-18
Applicant: VERTEX PHARMA
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公开(公告)号：FI2464337T4
公开(公告)日：2024-07-18
申请号：FI10708442
申请日：2010-02-18
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS , OVERHOFF KIRK , GROOTENHUIS PETER , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , VAN GOOR FREDRICK F
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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公开(公告)号：SI3345625T1
公开(公告)日：2021-04-30
申请号：SI200932107
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：DK3345625T3
公开(公告)日：2021-02-01
申请号：DK17204189
申请日：2009-08-13
Applicant: VERTEX PHARMA
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