公开(公告)号：KR101607861B1

公开(公告)日：2016-04-01

申请号：KR1020140075016

申请日：2014-06-19

Applicant: 한국식품연구원

Inventor： 박재호 ,  성미정 ,  황진택 ,  윤여초 ,  김성희 ,  류미라 ,  김혜영 ,  김민정

IPC: A61K36/896 ,  A61P11/02 ,  A61P11/00

Abstract: 본발명은둥글레추출물을유효성분으로함유하는후각과민증예방또는치료용약학조성물에관한것이다. 또한, 본발명은둥글레추출물을유효성분으로함유하는후각과민증예방또는개선용건강기능식품에관한것이다. 또한, 본발명은둥글레추출물을함유하는악취억제용방향제조성물에관한것이다. 본발명의옥죽을함유하는조성물은후각자극에의한 cAMP의생성을억제내지감소시켜다양한후각자극물질에대해뇌에서냄새인지를못하게하는역할을한다.

公开(公告)号：KR101427253B1

公开(公告)日：2014-08-14

申请号：KR1020120056917

申请日：2012-05-29

Applicant: 한국식품연구원

Inventor： 김병목 ,  김영명 ,  김동수 ,  황진택 ,  성미정 ,  정지희

IPC: A61K35/655 ,  A23L1/30

Abstract: 본 발명은 미더덕 추출물을 함유하는 지방산 산화용 조성물 또는 비만, 고지혈증, 인슐린 저항성 증후군 또는 대사성 증후군 개선용 약학 조성물 또는 건강기능식품에 관한 것으로, 더욱 상세하게 본 발명에 따르는 미더덕 추출물은 SREBP-1c, FAS(Fatty Acid Synthase) 및 ACC의 발현을 억제시켜 지방산 합성을 억제하는 효능을 가지며 특히 ACC의 발현 억제 및 CPT-1의 발현을 증가시켜 지방산의 산화를 촉진시킨다.

公开(公告)号：KR1020140088965A

公开(公告)日：2014-07-14

申请号：KR1020120158100

申请日：2012-12-31

Applicant: 한국식품연구원

Inventor： 허진영 ,  박재호 ,  성미정 ,  황진택

IPC: A61K36/28 ,  A61P11/00 ,  A61P25/00

Abstract: The present invention relates to a composition for preventing, treating, or alleviating transient receptor potential channel vanilloid subfamily member 1 (TRPV1)-mediated diseases, wherein the composition includes Lactuca raddeana as an active ingredient. The composition of the present invention is extracted from Lactuca raddeana, which is a natural plant material, and does not have side effects on the human body. The composition provides effects in preventing, treating, or alleviating pain and inflammation.

Abstract translation: 本发明涉及一种用于预防，治疗或缓解暂时性受体电位通道香草素亚族成员1（TRPV1）介导的疾病的组合物，其中该组合物包括莴苣乳杆菌作为活性成分。 本发明的组合物是天然植物材料的莴苣提取物，对人体无副作用。 该组合物提供预防，治疗或减轻疼痛和炎症的效果。

公开(公告)号：KR1020140080982A

公开(公告)日：2014-07-01

申请号：KR1020120150241

申请日：2012-12-21

Applicant: 한국식품연구원 ,  서천군

Inventor： 황진택 ,  양혜정 ,  성미정 ,  박재호

IPC: A23L33/00 ,  A23L2/38 ,  A61K36/342

CPC classification number: A23L33/105 ,  A23L2/38 ,  A23V2002/00 ,  A23V2200/332 ,  A23V2250/21 ,  A61K36/342 ,  A61K2236/33

Abstract: The present invention relates to a functional food for lowering cholesterol level, regulating weight, and improving nonalcoholic fatty liver, which contains the extract of Boehmeria nivea (L.) gaudich as an active ingredient. By containing Boehmeria nivea (L.) gaudich as an active ingredient, the function food can absorb blood sugar, decrease adipocytic differentiation, and reduce fatty liver, glucose, and fat content, and also is edible by not having toxicity.

Abstract translation: 本发明涉及含有Boehmeria nivea（L.）gaudich作为活性成分的提取物的降低胆固醇水平，调节重量和改善非酒精性脂肪肝的功能性食品。 通过含有Boehmeria nivea（L.）gaudich作为活性成分，功能食物可以吸收血糖，减少脂肪细胞分化，减少脂肪肝，葡萄糖和脂肪含量，也可通过无毒性食用。

公开(公告)号：KR101349083B1

公开(公告)日：2014-01-16

申请号：KR1020120020537

申请日：2012-02-28

Applicant: 한국식품연구원

Inventor： 김현진 ,  김명선 ,  황진택 ,  성미정 ,  박재호 ,  양혜정 ,  이경원 ,  허행전

IPC: G01N33/50 ,  G01N27/62 ,  G06F19/00

CPC classification number: Y02A90/26

Abstract: 본 발명은 간 추출물에 존재하는 특정 대사체의 농도를 측정하여 노화 진단을 위한 정보를 제공하는 방법 및 진단용 키트에 관한 것이다. 본 발명에 따르면 간 추출물에 존재하는 특정 대사체의 농도 변화를 측정하여 노화의 진행 여부 및 노화와 관련된 질병을 진단할 수 있고, 나아가 노화와 연관된 질병의 치료에 활용할 수 있다.

公开(公告)号：KR1020130078326A

公开(公告)日：2013-07-10

申请号：KR1020110147201

申请日：2011-12-30

Applicant: 한국식품연구원

Inventor： 권대영 ,  성미정 ,  황진택 ,  박재호 ,  양혜정 ,  김명선 ,  김현진 ,  허행전 ,  왕수옥 ,  다와세렌,뭉크투스 ,  윤석후

IPC: A61K31/353 ,  A61K9/08 ,  A61P17/00

Abstract: PURPOSE: A pharmaceutical composition containing auraptene as an active ingredient for promoting angiogenesis is provided to promote angiogenesis by auraptene, and to effectively regenerate tissues through skin flap regeneration, wound and burn healing, and artificial skin transplantation. CONSTITUTION: A pharmaceutical composition for promoting angiogenesis contains 1-10 micromole of auraptene as an active ingredient. Auraptene promotes tissue regeneration. The pharmaceutical composition is used for skin flap regeneration, wound and burn healing, artificial skin transplantation, or preparation of blood vessels for transplantation. A food composition for promoting angiogenesis contains auraptene as an active ingredient. Auraptene promotes angiogenesis. [Reference numerals] (AA) Control group; (BB) Auraptene 1μM; (CC) Auraptene 5μM; (DD) Auraptene 10μM; (EE) Auraptene 40μM

Abstract translation: 目的：提供含有紫罗烯作为促进血管发生的活性成分的药物组合物，用于促进紫罗烯烯的血管生成，并通过皮瓣再生，伤口和烧伤愈合以及人造皮肤移植有效地再生组织。 构成：用于促进血管发生的药物组合物含有1-10微摩尔的奥来哌啶作为活性成分。 Auraptene促进组织再生。 药物组合物用于皮瓣再生，伤口和烧伤愈合，人造皮肤移植或用于移植的血管制备。 用于促进血管生成的食品组合物含有作为活性成分的紫罗烯。 Auraptene促进血管生成。 （附图标记）（AA）对照组; （BB）Auraptene1μM; （CC）Auraptene5μM; （DD）Auraptene10μM; （EE）Auraptene40μM

公开(公告)号：KR1020120048205A

公开(公告)日：2012-05-15

申请号：KR1020100109716

申请日：2010-11-05

Applicant: 한국식품연구원

Inventor： 권대영 ,  성미정 ,  황진택 ,  박재호 ,  양혜정 ,  허행전 ,  김현진 ,  김명선

IPC: A61K31/198 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10

Abstract: PURPOSE: A pharmaceutical composition and health food containing methylselenocystein is provided to prevent and treat obesity and lipid-related metabolic diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity and lipid-related metabolic diseases contains methylselenocysteine as an active ingredient. The composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, oral formulation of aerosol, external use, suppository, or sterilized injection solution. A health food for preventing and relieving obesity and metabolic diseases contains methylselenocystein as an active ingredient. The health food is manufactured in the form of capsules, tablets, granules, powder, or beverage.

Abstract translation: 目的：提供含有甲基硒代半胱氨酸的药物组合物和保健食品，用于预防和治疗肥胖症和与脂质有关的代谢疾病。 构成：用于预防和治疗肥胖症和脂质相关代谢疾病的药物组合物含有甲基硒代半胱氨酸作为活性成分。 该组合物以粉末，颗粒，片剂，胶囊，悬浮液，乳剂，糖浆，气雾剂口服制剂，外用，栓剂或灭菌注射液的形式制备。 用于预防和缓解肥胖和代谢疾病的保健食品含有甲基硒代半胱氨酸作为活性成分。 保健食品以胶囊，片剂，颗粒，粉末或饮料的形式制造。

公开(公告)号：KR1020120004828A

公开(公告)日：2012-01-13

申请号：KR1020100065515

申请日：2010-07-07

Applicant: 한국식품연구원

Inventor： 권대영 ,  성미정 ,  황진택 ,  박재호 ,  양혜정 ,  김명선 ,  김현진 ,  허행전

IPC: A61K31/05 ,  A61K31/045 ,  A61P29/00

Abstract: PURPOSE: A 2,4 D-tertiary-butylphenol or salt thereof for anti-inflammation is provided to suppress iNOS expression and to prevent and treat inflammation. CONSTITUTION: An anti-inflammatory composition contains 2,4 D-tertiary-butylphenol or salt thereof as an active ingredient. A pharmaceutical composition for preventing and treating inflammation contains 2,4 D-tertiary phenol or pharmacologically acceptable salt thereof as an active ingredient. A food composition for preventing and treating inflammation contains 0.01-10 wt% of 2,4-D-tertiary-butylphenol or sitologically acceptable salt thereof as an active ingredient. The salt is acid addition salt.

Abstract translation: 目的：提供用于抗炎的2,4-二叔丁基苯酚或其盐以抑制iNOS表达并预防和治疗炎症。 构成：抗炎组合物含有2,4-二叔丁基苯酚或其盐作为活性成分。 用于预防和治疗炎症的药物组合物含有2,4-二叔酚或其药理学上可接受的盐作为活性成分。 用于预防和治疗炎症的食品组合物含有0.01-10重量％的2,4-D-叔丁基苯酚或其可以选择的盐作为活性成分。 盐是酸加成盐。

公开(公告)号：KR1020110058097A

公开(公告)日：2011-06-01

申请号：KR1020090114765

申请日：2009-11-25

Applicant: 한국식품연구원

Inventor： 이영철 ,  노정해 ,  이영경 ,  김경탁 ,  조장원 ,  홍희도 ,  김영찬 ,  최상윤 ,  황진택

IPC: C12N1/14 ,  A61K31/70 ,  A61P3/10 ,  A23L2/38

Abstract: PURPOSE: A composition containing Ganoderma resinaceum KFRI-M101(KFCC 11429P) is provided to increase AMPK activity, to lower blood glucose, and prevent and treat diabetes. CONSTITUTION: A Ganoderma resinaceum KFRI-M101(KFCC 11429P) is used for metabolism of ginsenoside ingredient. A composition for preventing and treating contains ginseng fermentation which is obtained by fermenting ginseng with Ganoderma resinaceum KFRI-M101(KFCC 11429P) at 20°C-30°C and 40-80% of moisture for 2-8 weeks. The composition also contains ginseng extract as an active ingredient, which is obtained by isolating the ginseng fermentation with water, ethanol, or mixture thereof at 90-110°C for 2-4 hours. The composition is a health food.

Abstract translation: 目的：提供含有灵芝树胶囊KFRI-M101（KFCC 11429P）的组合物，以增加AMPK活性，降低血糖，预防和治疗糖尿病。 构成：灵芝树胶囊KFRI-M101（KFCC 11429P）用于人参皂苷成分的代谢。 用于预防和治疗的组合物包含人参发酵，其通过用20℃-30℃的Ganoderma resinaceum KFRI-M101（KFCC 11429P）和40-80％的水分发酵人参2-8周获得。 该组合物还含有作为活性成分的人参提取物，其通过在90-110℃下将水，乙醇或其混合物的人参发酵分离2-4小时而获得。 组合物是保健食品。

公开(公告)号：KR1020110053123A

公开(公告)日：2011-05-19

申请号：KR1020090109950

申请日：2009-11-13

Applicant: 한국식품연구원

Inventor： 김혜영 ,  김동현 ,  이영경 ,  한찬규 ,  황진택 ,  이영철 ,  민성원 ,  김경 ,  박민

IPC: C12N1/20 ,  A23L19/00 ,  A23L2/72

Abstract: PURPOSE: A novel Pediococcus pentosaceus K-643(KFCC11464P) is provided to improve glucose homeostasis. CONSTITUTION: A novel Pediococcus pentosaceus K-643(KFCC11464P) is used in fermenting ginseng. A method for preparing the ginseng fermentation extract comprises: a step of fermenting ginseng with Pediococcus pentosaceus K-643(KFCC11464P) to obtain a fermentation; and a step of extracting the fermentation with a solvent and filtering. A pharmaceutical formulation and health food for maintaining or improving glucose homeostasis contains ginseng fermentation extract.

Abstract translation: 目的：提供一种新型戊糖片球菌K-643（KFCC11464P），以改善葡萄糖体内平衡。 构成：一种新型戊糖片球菌K-643（KFCC11464P）用于发酵人参。 一种人参发酵提取物的制备方法，其特征在于：使用戊糖片球菌K-643（KFCC11464P）发酵人参以获得发酵的步骤; 和用溶剂萃取发酵并过滤的步骤。 用于维持或改善葡萄糖体内平衡的药物制剂和保健食品包含人参发酵提取物。