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公开(公告)号：YU46701A
公开(公告)日：2004-05-12
申请号：YU46701
申请日：1999-12-29
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , VON GELDERN TOM , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10
Abstract: Predmetni pronalazak se odnosi na nove amide cimetne kiseline, koji su korisni u tretiranju zapaljenskih i imunoloških oboljenja, na farmaceutske preparate koji sadrže ova jedinjenja i na postupke inhibicije zapaljenja ili supresije imunog odgovora kod sisara.
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公开(公告)号：EE200100513A
公开(公告)日：2002-12-16
申请号：EEP200100513
申请日：2000-04-03
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , GELDERN THOMAS W VON , WINN MARTIN , XIN ZHILI , WANG SHELDON , BOYD STEVEN A , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A , JAE HWAN-SOO , LYNCH JOHN K
IPC: C07D243/08 , A61K20060101 , A61K31/10 , A61K31/165 , A61K31/33 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/472 , A61K31/496 , A61K31/4965 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61K31/55 , A61K31/551 , A61P20060101 , A61P29/00 , A61P37/06 , C07C20060101 , C07C323/60 , C07C323/62 , C07D20060101 , C07D205/04 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/26 , C07D207/27 , C07D207/273 , C07D209/08 , C07D209/12 , C07D211/20 , C07D211/22 , C07D211/46 , C07D211/60 , C07D211/62 , C07D211/64 , C07D211/66 , C07D211/70 , C07D213/40 , C07D213/74 , C07D213/81 , C07D215/24 , C07D217/02 , C07D217/04 , C07D217/06 , C07D233/61 , C07D239/42 , C07D241/04 , C07D241/24 , C07D257/04 , C07D279/12 , C07D295/18 , C07D295/185 , C07D295/20 , C07D295/205 , C07D295/22 , C07D295/26 , C07D307/24 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/66 , C07D319/18 , C07D401/04 , C07D401/12 , C07D405/12 , C07D417/12 , C07D471/20 , C07D487/04 , C07D491/113 , C07D521/00
Abstract: The present invention relates to cinnamide compounds of formula (I), in which at least one of R1 to R5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims, that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal.
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公开(公告)号：DK0888340T3
公开(公告)日：2002-11-04
申请号：DK97905897
申请日：1997-02-10
Applicant: ABBOTT LAB
Inventor： TASKER ANDREW S , BOYD STEVEN A , SORENSEN BRYAN K , WINN MARTIN , JAE HWAN-SOO , VON GELDERN THOMAS W , HENRY KENNETH J
IPC: A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/675 , A61P1/00 , A61P7/00 , A61P9/00 , A61P11/00 , A61P13/12 , A61P25/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D419/14 , C07D453/02 , C07F9/572
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公开(公告)号：AT220673T
公开(公告)日：2002-08-15
申请号：AT97905897
申请日：1997-02-10
Applicant: ABBOTT LAB
Inventor： TASKER ANDREW S , BOYD STEVEN A , SORENSEN BRYAN K , WINN MARTIN , JAE HWAN-SOO , VON GELDERN THOMAS W , HENRY KENNETH J
IPC: A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/675 , A61P1/00 , A61P7/00 , A61P9/00 , A61P11/00 , A61P13/12 , A61P25/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D419/14 , C07D453/02 , C07F9/572
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公开(公告)号：AT219077T
公开(公告)日：2002-06-15
申请号：AT95928323
申请日：1995-08-04
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , VONGELDERN THOMAS W , KESTER JEFFREY A , SORENSEN BRYAN K
IPC: A61K31/40 , A61K31/402 , A61K31/4025 , A61K31/403 , A61K31/41 , A61K31/415 , A61K31/422 , A61K31/435 , A61K31/44 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/47 , A61K31/505 , A61K31/506 , A61K31/535 , A61K31/5377 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , A61P29/00 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/14 , C07D207/16 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/10 , C07D405/14 , C07D413/04 , C07D419/04 , C07D471/04 , C07F9/572 , C07F9/59
Abstract: Processes for preparing endothelin antagonists of formula (I) and pharmaceutically acceptable salts thereof and processes for preparing intermediates thereof.
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Patent Agency Ranking
公开(公告)号：AU748469B2
公开(公告)日：2002-06-06
申请号：AU8592198
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , GELDERN THOMAS W VON , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY KENNETH J , LIU GANG , WITTENBERGER STEVEN J , KING STEVEN A
IPC: C07D491/048 , A61K31/40 , A61K31/41 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/495 , A61K31/506 , A61K31/535 , A61K31/55 , A61P1/00 , A61P1/04 , A61P7/02 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/08 , A61P13/12 , A61P21/00 , A61P21/04 , A61P25/06 , A61P35/00 , A61P43/00 , C07D207/16 , C07D207/26 , C07D207/27 , C07D403/04 , C07D405/00 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D491/056
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公开(公告)号：BG105732A
公开(公告)日：2002-02-28
申请号：BG10573201
申请日：2001-07-25
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , VON GELDERN TOM , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10
Abstract: The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal. 24 claims
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公开(公告)号：IS5985A
公开(公告)日：2001-06-28
申请号：IS5985
申请日：2001-06-28
Applicant: ABBOTT LAB CHAD 0377 AP6D 2
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , GELDERN TOM VON , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWAR-DANA INDRANI W , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10
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公开(公告)号：SK1452000A3
公开(公告)日：2001-05-10
申请号：SK1452000
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , GELDERN THOMAS W VON , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY KENNETH J , LIU GANG , WITTENBERGER STEVEN J , KING STEVEN A
IPC: C07D491/048 , A61K31/40 , A61K31/41 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/495 , A61K31/506 , A61K31/535 , A61K31/55 , A61P1/00 , A61P1/04 , A61P7/02 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/08 , A61P13/12 , A61P21/00 , A61P21/04 , A61P25/06 , A61P35/00 , A61P43/00 , C07D207/16 , C07D207/26 , C07D207/27 , C07D403/04 , C07D405/00 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D491/056
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公开(公告)号：NO20006157L
公开(公告)日：2001-02-02
申请号：NO20006157
申请日：2000-12-04
Applicant: ABBOTT LAB
Inventor： STEWART ANDREW O , BOYD STEVEN A , ARENDSEN DAVID L , BHATIA PRAMILA , CONDROSKI KEVIN R , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , ZHU GUI-DONG , LARTEY KRAIG , MCCARTY CATHERINE M , MORT NICHOLAS A , PATEL MEENA V , STAEGER MICHAEL A , STOUT DAVID M
IPC: A61K31/4355 , A61K31/4365 , A61K31/437 , A61K31/444 , A61K31/4545 , A61K31/497 , A61K31/519 , A61K31/5377 , A61P29/00 , C07D471/04 , C07D491/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D513/04 , C07D
Abstract: Compounds having Formula (I) are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compouns of Formula (I), and methods of inhibiting/treating inflammatory diseases in a mammal.
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