公开(公告)号：GR75401B

公开(公告)日：1984-07-13

申请号：GR810166900

申请日：1981-12-23

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  STEINER GERD DR ,  THIEME PETER C DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：GR74171B

公开(公告)日：1984-06-07

申请号：GR810165006

申请日：1981-05-20

Applicant: BASF AG

Inventor： THYES MARCO DR ,  KOENIG HORST DR ,  LENKE DIETER DR ,  LEHMANN HANS DIETER DR ,  GRIES JOSEF DR

IPC: A61K31/50 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04

Abstract: Novel 6-(p-acylaminophenyl)-4,5-dihydro-3(2H)-pyridazinones, whose acyl radical is derived from a cycloalkylcarboxylic acid, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in thrombo-embolic disorders and as anti-hypertensives.

公开(公告)号：DE3161340D1

公开(公告)日：1983-12-15

申请号：DE3161340

申请日：1981-01-28

Applicant: BASF AG

Inventor： THIEME PETER C DR ,  FRANKE ALBRECHT DR ,  LENKE DIETER DR ,  LEHMANN HANS DIETER DR ,  GRIES JOSEF DR

IPC: C07D413/12 ,  A61K31/495 ,  A61K31/496 ,  A61P9/12 ,  C07D271/10 ,  C07D405/12

Abstract: Novel phenylpiperazinylpropanols of 1,3,4-oxadiazolylphenols and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and are useful in the treatment of hypertonia.

公开(公告)号：DE3144150A1

公开(公告)日：1982-12-09

申请号：DE3144150

申请日：1981-11-06

Applicant: BASF AG

Inventor： DENGEL FERDINAND DIPL CHEM DR ,  EHRMANN OSKAR DIPL CHEM DR ,  FRANK WOLFRAM DR ,  FRIEDRICH LUDWIG DR ,  GRIES JOSEF DR ,  KRETZSCHMAR ROLF PROF DR MED ,  KURBJUWEIT HANS-GEORG DR ,  MUELLER CLAUS D DR MED ,  RASCHACK MANFRED DR ,  SEITZ WERNER DIPL CHEM DR ,  TREIBER HANS JOERG DR ,  WUPPERMANN DIRK DR MED ,  ZIMMERMANN FRANK DR MED

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  C07C121/78

公开(公告)号：DE2962917D1

公开(公告)日：1982-07-08

申请号：DE2962917

申请日：1979-11-08

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR DIPL CHEM ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  LEHMANN HANS DIETER DR

IPC: A61K31/55 ,  C07D223/16 ,  C07D405/12

公开(公告)号：ES2039516T3

公开(公告)日：1995-04-01

申请号：ES88111911

申请日：1988-07-23

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  SCHLECKER RAINER DR ,  GRIES JOSEF DR ,  VON PHILIPSBORN GERDA DR ,  UNGER LILIANE DR

IPC: A61K31/135 ,  A61P9/06 ,  A61P25/02

Abstract: The agents are prepared as described and used for certain groups of patients.

公开(公告)号：AT90339T

公开(公告)日：1993-06-15

申请号：AT87117946

申请日：1987-12-04

Applicant: BASF AG

Inventor： SEITZ WERNER DR ,  UNGER LILIANE DR ,  RASCHACK MANFRED DR ,  BALDINGER VERENA DR ,  RUEBSAMEN KLAUS DR ,  GRIES JOSEF DR

IPC: A61K31/275 ,  A61K31/335 ,  A61K31/357 ,  A61K31/36 ,  A61P1/04 ,  A61P3/00 ,  A61P9/00 ,  A61P11/00 ,  A61P43/00 ,  C07C67/00 ,  C07C253/00 ,  C07C253/30 ,  C07C255/32 ,  C07C255/33 ,  C07C255/35 ,  C07C255/37 ,  C07C255/42 ,  C07C255/53 ,  C07C255/58 ,  C07D317/50 ,  C07D317/60 ,  C07D319/08 ,  C07D319/18 ,  C07D321/00

公开(公告)号：AT53210T

公开(公告)日：1990-06-15

申请号：AT87100041

申请日：1987-01-03

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  SCHMIED BERNHARD DR ,  KROPP RUDOLF ,  BALDINGER VERENA DR ,  GRIES JOSEF DR ,  LEHMANN HANS DIETER PROF DR ,  RUEBSAMEN KLAUS DR ,  TRAUT MARTIN DR

IPC: C07D237/00 ,  A61K31/50 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D403/04 ,  C07D403/10

公开(公告)号：AT46687T

公开(公告)日：1989-10-15

申请号：AT86116409

申请日：1986-11-26

Applicant: BASF AG

Inventor： SEITZ WERNER DR ,  BALDINGER VERENA DR ,  GRIES JOSEF DR ,  LENKE DIETER PROF DR ,  RASCHACK MANFRED DR ,  RUEBSAMEN KLAUS DR

IPC: A61K31/135 ,  A61P1/04 ,  A61P9/00 ,  A61P9/12 ,  C07C223/02 ,  C07D317/58 ,  C07D319/18 ,  C07D325/00 ,  C07C95/08

公开(公告)号：DE3567211D1

公开(公告)日：1989-02-09

申请号：DE3567211

申请日：1985-07-05

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  SCHMIED BERNHARD DR ,  RASCHACK MANFRED DR ,  LEHMANN HANS-DIETER PROF DR ,  GRIES JOSEF DR ,  RUEBSAMEN KLAUS DR

IPC: A61K31/50 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D237/00 ,  C07D403/04 ,  C07D403/10

Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula I their preparation and their use in the treatment of disorders.