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公开(公告)号：KR1020140136843A
公开(公告)日：2014-12-01
申请号：KR1020130057429
申请日：2013-05-21
Applicant: 강원대학교산학협력단
Abstract: The present invention relates to a composition for improving, treating or preventing neurodegenerative disease containing an oenanthe javanica extract as an active ingredient wherein the composition of the present invention increases the proliferation and differentiation of endogenous neural stem cells, which efficiently induces the regeneration of neuron cells and accordingly treats, improves or prevents neurodegenerative disease caused by neuron cells damaged by aging or brain diseases and functional problems like memory loss and cognitive dysfunction. In the present invention, the composition uses natural substances whose safety is recognized and which have little possibility of generating side effects, so the composition can be widely used for treating, improving or preventing neurodegenerative disease.
Abstract translation: 本发明涉及一种用于改善，治疗或预防神经变性疾病的组合物，其含有爪哇爪提取物作为活性成分，其中本发明的组合物增加内源性神经干细胞的增殖和分化，其有效诱导神经元细胞的再生 因此治疗，改善或预防由衰老或脑部疾病以及如记忆丧失和认知功能障碍等功能性问题引起的神经元细胞引起的神经变性疾病。 在本发明中，组合物使用其安全性被认可并且几乎不产生副作用的天然物质，因此该组合物可广泛用于治疗，改善或预防神经变性疾病。
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公开(公告)号：KR1020100000693A
公开(公告)日：2010-01-06
申请号：KR1020080060286
申请日：2008-06-25
Applicant: 강원대학교산학협력단
CPC classification number: A23L33/105 , A23L33/125 , A23V2002/00 , A23V2200/302 , A23V2250/21
Abstract: PURPOSE: A functional food for promoting differentiation of neutral stem cell containing platycodon root extract as an active ingredient is provided to suppress the reduction of differentiation of proliferation of neutral stem cells caused by aging and to promote differentiation of proliferation of neutral stem cells. CONSTITUTION: A functional food comprises platycodon root extract as an active ingredient to promote differentiation of proliferation of neutral stem cells. The nerve stem cells are derivated from dentate gyrus subgranular zone of hippocampus. The differentiation of the stem cell comprises the production of stem cells, fission, differentiation and movement. The platycodon root extract is obtained by cutting the dried platycodon root; extracting it at 20-150deg.C through enfleurage extraction, hot water extraction, ultrasonic extraction, and extraction under reflux condensation.
Abstract translation: 目的：提供一种促进中性干细胞含有桔梗根提取物作为活性成分的功能性食品，以抑制由老化引起的中性干细胞增殖分化的减少，并促进中性干细胞增殖的分化。 构成：功能性食品包括桔梗根提取物作为活性成分，促进中性干细胞增殖的分化。 神经干细胞衍生自海马齿状回颗粒亚区域。 干细胞的分化包括干细胞的产生，分裂，分化和运动。 通过切割干燥的桔梗根获得桔梗根提取物; 通过灌肠提取，热水提取，超声提取，回流冷凝提取，在20-150℃下萃取。
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公开(公告)号：KR101537803B1
公开(公告)日：2015-07-22
申请号：KR1020130162837
申请日：2013-12-24
Applicant: 강원대학교산학협력단
CPC classification number: Y02A40/943
Abstract: 본발명은 (a) 물에천일염및 식초를넣어절임수를제조하는단계; 및 (b) 민들레잎을상기 (a)단계의절임수에넣고절인후 꺼내어, 숙성시키는단계를포함하여제조하는것을특징으로하는민들레김치의제조방법, 상기방법으로제조된민들레김치및 이를이용하여제조된가공식품에관한것이다.
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Patent Agency Ranking
公开(公告)号：KR1020130085680A
公开(公告)日：2013-07-30
申请号：KR1020120006628
申请日：2012-01-20
Applicant: 강원대학교산학협력단
CPC classification number: A23L19/03 , A23L3/40 , A23L5/13 , A23V2002/00 , A23V2200/30
Abstract: PURPOSE: A production method of cooked dandelion dish is provided to provide excellent anti-oxidation ability functionality of dandelion. CONSTITUTION: Dandelion is parboiled at 80-90°C for 3-5 minutes. The parboiled dandelion is cooled to a room temperature. The cooled dandelion is dried at 40-50°C for 6-9 hours. The parboiling step is conducted for 5 minutes at 90°C. The drying step is conducted for 9 hours at 40°C. [Reference numerals] (AA) Dandelion; (BB) Parboil at 90°C; (CC) Cool; (DD) Dry; (EE) Dried product; (FF) Dandelion greens jelly macerated in water
Abstract translation: 目的：提供熟蒲公英菜的生产方法，以提供蒲公英优异的抗氧化功能。 构成：蒲公英在80-90℃下煮沸3-5分钟。 将煮沸的蒲公英冷却至室温。 将冷却的蒲公英在40-50℃下干燥6-9小时。 脱蜡步骤在90℃下进行5分钟。 干燥步骤在40℃下进行9小时。 （附图标记）（AA）蒲公英; （BB）Parboil在90°C; （CC）酷; （DD）干; （EE）干燥产品; （FF）蒲公英绿色果冻浸在水中
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公开(公告)号：KR1020120053604A
公开(公告)日：2012-05-29
申请号：KR1020100114798
申请日：2010-11-18
Applicant: 강원대학교산학협력단
IPC: A61K36/344 , A61P25/28 , A61P25/00 , A61P9/10
Abstract: PURPOSE: A composition containing Codonopsis lanceolat extract is provided to suppress neuron apoptosis and glial cell activity and to effectively prevent neural injury. CONSTITUTION: A composition for preventing or treating ischemic cerebral diseases contains Codonopsis lanceolat extract as an active ingredient. The diseases include cerebral infarction, cerebral hemorrhage, senile dementia, Alzheimer disease, Parkinson's disease, Huntington disease, or thromboembolism. The extract is isolated using water, alcohol of 1-5 carbon atoms or mixture thereof. A food composition for preventing or treating the diseases contains the extract as an active ingredient.
Abstract translation: 目的：提供含有党参提取物的组合物，以抑制神经元凋亡和神经胶质细胞活性，有效预防神经损伤。 构成：用于预防或治疗缺血性脑疾病的组合物含有党参提取物作为活性成分。 这些疾病包括脑梗塞，脑出血，老年痴呆，阿尔茨海默病，帕金森病，亨廷顿疾病或血栓栓塞。 使用水，1-5个碳原子的醇或其混合物分离提取物。 用于预防或治疗疾病的食品组合物含有提取物作为活性成分。
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公开(公告)号：KR1020150074761A
公开(公告)日：2015-07-02
申请号：KR1020130162837
申请日：2013-12-24
Applicant: 강원대학교산학협력단
CPC classification number: Y02A40/943 , A23B7/10 , A23L19/00
Abstract: 본발명은 (a) 물에천일염및 식초를넣어절임수를제조하는단계; 및 (b) 민들레잎을상기 (a)단계의절임수에넣고절인후 꺼내어, 숙성시키는단계를포함하여제조하는것을특징으로하는민들레김치의제조방법, 상기방법으로제조된민들레김치및 이를이용하여제조된가공식품에관한것이다.
Abstract translation: 本发明涉及通过该方法制造的蒲公英泡菜，蒲公英泡菜的制造方法以及使用该方法制造的加工食品，其特征在于，包括以下步骤：（a）将盐水和水加入水中制造盐水; 和（b）在步骤（a）中将蒲公英的叶子放入盐水中进行盐析后，拔出和老化。
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公开(公告)号：KR1020140033905A
公开(公告)日：2014-03-19
申请号：KR1020120100420
申请日：2012-09-11
Applicant: 강원대학교산학협력단 , 주식회사 엔자임바이오
Abstract: The present invention relates to a composition comprising an Oenanthe javanica extract for preventing or alleviating a brain ischemia disease and, more specifically, to a composition comprising an Oenanthe javanica extract for preventing or alleviating a brain ischemia disease which is expected to be variously used for treatment, prevention, or alleviation of diseases caused by brain ischemia since the Oenanthe javanica has excellent neuroprotective ability for hippocampal brain and neuronal death inhibitory ability, is confirmed that inhibitory ability of glial activation is superior, effectively prevents a nerve damage of hippocampal CA1 region of the brain that is known as to be sensitive for the ischemia, and is harmless to the human body.
Abstract translation: 本发明涉及一种组合物，其包含用于预防或减轻脑缺血疾病的美洲爪哇ica提取物，更具体地，涉及一种包含用于预防或减轻预期用于治疗的脑缺血疾病的美洲爪蟾提取物的组合物 预防或缓解脑缺血引起的疾病，因为爪哇ica对海马脑神经保护能力和神经元死亡抑制能力均有优异的表现，证实了胶质细胞活化的抑制能力优越，有效防止了海马CA1区神经损伤 被认为对缺血敏感的大脑，对人体无害。
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公开(公告)号：KR101290749B1
公开(公告)日：2013-07-29
申请号：KR1020100114798
申请日：2010-11-18
Applicant: 강원대학교산학협력단
IPC: A61K36/344 , A61P25/28 , A61P25/00 , A61P9/10
Abstract: 본 발명은 더덕 추출물을 유효성분으로 포함하는 허혈성 뇌혈관 질환 예방 또는 개선용 조성물에 관한 것으로, 보다 상세하게는 상기 더덕 추출물은 뇌 해마조직의 신경세포 보호능 및 신경세포사 억제능이 우수하고, 아교세포의 활성화 억제능이 뛰어나다는 것이 확인되어, 뇌허혈에 민감하다고 알려져 있는 뇌 해마조직 CA1 영역의 신경 손상을 효과적으로 예방할 뿐만 아니라, 인체에 무해하여, 상기 더덕 추출물을 유효성분으로 포함하는 허혈성 뇌혈관 질환 예방 또는 개선용 조성물은 뇌허혈에 의한 질환의 치료, 예방 또는 개선을 위해 다양하게 응용될 수 있을 것으로 기대된다.
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