公开(公告)号：US20160161402A1

公开(公告)日：2016-06-09

申请号：US15046850

申请日：2016-02-18

Applicant: Innovative Science Tools, Inc.

Inventor： Ronald H. Micheels ,  Don J. Lee

IPC: G01N21/359 ,  G01N21/3577 ,  G01N21/3563

CPC classification number: G01N21/359 ,  G01J3/0205 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/9508 ,  G01N2201/06153 ,  G01N2201/0627 ,  G01N2201/0631

Abstract: A device and method for identifying solid and liquid materials use near-infrared transmission spectroscopy combined with multivariate calibration methods for analysis of the spectral data. Near-infrared transmission spectroscopy is employed within either the 700-1100 nm or the 900-1700 nm wavelength range to identify solid or liquid materials and determine whether they match specific known materials. Uses include identifying solid (including powdered) and liquid materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or liquid sample that consists of a mixture of components. A primary application of such analysis includes detection of counterfeit drug tablets, capsules and liquid medications.

公开(公告)号：US09360415B2

公开(公告)日：2016-06-07

申请号：US14263942

申请日：2014-04-28

Applicant: SpectraSensors, Inc.

Inventor： Xiang Liu ,  John Lewison ,  Wenhai Ji ,  Alfred Feitisch

IPC: G01N21/00 ,  G01N21/27 ,  G01N21/39 ,  G01N21/3504 ,  G01J3/28 ,  G01J3/42 ,  G01N21/03 ,  G01N21/31 ,  G01N21/3518

CPC classification number: G01N21/274 ,  G01J3/28 ,  G01J3/42 ,  G01N21/031 ,  G01N21/31 ,  G01N21/3504 ,  G01N21/3518 ,  G01N21/39 ,  G01N2021/399

Abstract: A reference harmonic absorption curve of a laser absorption spectrometer can have a reference curve shape derived from a reference signal generated by the detector in response to light passing from the laser light source through a reference gas or gas mixture. The reference gas or gas mixture can include one or more of a target analyte and a background gas expected to be present during analysis of the target analyte. A test harmonic absorption curve having a test curve shape is compared with the reference harmonic absorption curve to detect a difference between the test curve shape and the reference curve shape. Operating and/or analytical parameters of the laser absorption spectrometer are adjusted to correct the test curve shape to reduce the difference between the test curve shape and the reference curve shape.

Abstract translation: 激光吸收光谱仪的参考谐波吸收曲线可以具有根据由检测器响应于从激光源通过参考气体或气体混合物的光而产生的参考信号导出的参考曲线形状。 参考气体或气体混合物可以包括目标分析物和预期在目标分析物的分析期间存在的背景气体中的一种或多种。 将具有测试曲线形状的测试谐波吸收曲线与参考谐波吸收曲线进行比较，以检测测试曲线形状与参考曲线形状之间的差异。 调整激光吸收光谱仪的操作和/或分析参数以校正测试曲线形状，以减小测试曲线形状与参考曲线形状之间的差异。

公开(公告)号：US20160146666A1

公开(公告)日：2016-05-26

申请号：US14950617

申请日：2015-11-24

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Yoichi KAWADA ,  Takashi YASUDA ,  Hironori TAKAHASHI

IPC: G01J1/44 ,  G01J1/42 ,  G01J1/04 ,  G01J4/04

CPC classification number: G01J1/44 ,  G01J1/0429 ,  G01J1/4228 ,  G01J3/0224 ,  G01J3/0262 ,  G01J3/42 ,  G01J3/433 ,  G01J3/4338 ,  G01J4/04 ,  G01J2001/4242 ,  G01N21/3581 ,  G01R15/241 ,  G01R29/0871

Abstract: In this electric field vector detection method, an electro-optic crystal, where a (111) surface of an optical isotropic medium is cut out, is used as a terahertz wave detection element. The method includes: causing polarization of probe light of ultrashort pulsed light to be circular polarization; allowing the probe light having circular polarization to enter the terahertz wave detection element and probing the terahertz wave; modulating the probe light, having probed the terahertz wave, by a rotating analyzer and detecting the modulated probe light by a photodetector; performing lock-in detection of a detection signal from the photodetector by a lock-in detector using a frequency based on a rotational frequency of the rotating analyzer as a reference signal; and detecting an electric field vector of the terahertz wave based on a detection signal from the lock-in detector.

Abstract translation: 在该电场矢量检测方法中，将光学各向同性介质的（111）面切出的电光晶体用作太赫兹波检测元件。 该方法包括：使超短脉冲光的探测光的极化成圆极化; 允许具有圆极化的探测光进入太赫兹波检测元件并探测太赫兹波; 通过旋转分析仪调制探测太赫兹波的探测器，并通过光电检测器检测调制的探测光; 通过锁定检测器使用基于旋转分析仪的旋转频率的频率作为参考信号来执行来自光电检测器的检测信号的锁定检测; 以及基于来自锁定检测器的检测信号检测太赫兹波的电场矢量。

公开(公告)号：US20160138904A1

公开(公告)日：2016-05-19

申请号：US15004933

申请日：2016-01-23

Applicant: Massachusetts Institute of Technology

Inventor： Andreas Velten ,  Ramesh Raskar

IPC: G01B11/00 ,  G01N21/64 ,  G01N21/55

CPC classification number: G01B11/002 ,  G01B11/2513 ,  G01J3/021 ,  G01J3/027 ,  G01J3/10 ,  G01J3/42 ,  G01N21/255 ,  G01N21/27 ,  G01N21/55 ,  G01N21/64 ,  G01N21/6456 ,  G01N2021/3129 ,  G01N2021/6417 ,  G01N2201/061

Abstract: An active imaging system, which includes a light source and light sensor, generates structured illumination. The light sensor captures transient light response data regarding reflections of light emitted by the light source. The transient light response data is wavelength-resolved. One or more processors process the transient light response data and data regarding the structured illumination to calculate a reflectance spectra map of an occluded surface. The processors also compute a 3D geometry of the occluded surface.

Abstract translation: 包括光源和光传感器的主动成像系统产生结构化照明。 光传感器捕获关于光源发射的光的反射的瞬态光响应数据。 瞬态光响应数据经波长分辨。 一个或多个处理器处理关于结构化照明的瞬态光响应数据和数据，以计算遮挡表面的反射光谱图。 处理器还计算封闭表面的3D几何形状。

公开(公告)号：US09341515B2

公开(公告)日：2016-05-17

申请号：US13370969

申请日：2012-02-10

Applicant: Alfons Schulte ,  Silki Arora

Inventor： Alfons Schulte ,  Silki Arora

IPC: G01J3/42 ,  G02B21/00 ,  G01J3/02 ,  G01J3/427 ,  G01N21/03 ,  G01N21/31 ,  G02B21/26 ,  G02B21/36 ,  G01N21/05 ,  G01N21/65

CPC classification number: G01J3/42 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0289 ,  G01J3/427 ,  G01N21/03 ,  G01N21/31 ,  G01N21/314 ,  G01N21/3151 ,  G01N2021/0346 ,  G01N2021/058 ,  G01N2021/651 ,  G01N2021/656 ,  G01N2201/0627 ,  G01N2201/0846 ,  G02B21/0028 ,  G02B21/0032 ,  G02B21/26 ,  G02B21/367

Abstract: Apparatus and method to measure optical absorption spectra with spatial resolution on the micron scale. An exemplary setup combines a continuous white light excitation beam in transmission geometry with a confocal microscope. Spatial resolution better than 1.4 μm in the lateral and 3.6 μm in the axial, directions was obtained. The detection and measurement of the absorption spectrum of hemoglobin in a single red blood cell under physiological conditions on the timescale of seconds was realized. The apparatus and method enables the investigation of spatial variations in the optical density of small samples on the micron scale and the study of biological assemblies at the single cell level, leading to applications in optical diagnostics, microfluidics, and other areas.

Abstract translation: 用微米尺度测量空间分辨率的光吸收光谱的装置和方法。 示例性设置将透射几何中的连续白光激发光束与共聚焦显微镜组合。 获得横向分辨率优于1.4μm，轴向方向为3.6μm。 实现了在生理条件下单次红细胞血红蛋白吸收光谱在秒的时间刻度上的检测和测量。 该装置和方法能够调查微尺度上小样品的光密度的空间变化以及在单细胞水平上对生物组装的研究，导致在光学诊断，微流体等领域的应用。

公开(公告)号：US20160131889A1

公开(公告)日：2016-05-12

申请号：US14898524

申请日：2014-06-20

Applicant: NEC CORPORATION

Inventor： Takao MORIMOTO ,  Takayuki SUDOU

IPC: G02B21/36 ,  G01J1/04 ,  G01J1/42

CPC classification number: G02B21/361 ,  G01J1/0407 ,  G01J1/42 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0229 ,  G01J3/42 ,  G01N21/3581 ,  G02B21/0004

Abstract: [Object] To provide an optical device for use with coherent terahertz light, which enables to reduce and remove an unwanted interference pattern, and to acquire a terahertz image of high image quality.[Solving Means] The optical device for use with coherent terahertz light includes an optical system (2) that uses coherent terahertz light beam (1) whose frequency(ies) is/are within a range from 0.1 to 10 THz. A structure(s) (4) being located outside of effective diameter (3) of the beam (1) and including anti-reflection material (5) on an area(s) of the structure, the area(s) is/are facing to the beam (1).

Abstract translation: 提供一种用于相干太赫兹光的光学装置，其能够减少和去除不需要的干涉图案，并获得高图像质量的太赫兹图像。 [解决方案]用于相干太赫兹光的光学装置包括使用其频率在0.1至10THz范围内的相干太赫兹光束（1）的光学系统（2）。 一种结构（4）位于梁（1）的有效直径（3）的外侧，并且在该结构的一个或多个区域上包括防反射材料（5），该区域是 面向梁（1）。

公开(公告)号：US09329123B2

公开(公告)日：2016-05-03

申请号：US14424850

申请日：2013-08-06

Applicant: NewSouth Innovations Pty Limited

Inventor： Charles Charbel Harb

IPC: G01N21/39 ,  G01J3/42 ,  H01S3/08 ,  G01N21/3504 ,  G01N21/03 ,  G01J3/02 ,  G01J3/10 ,  G01J3/427 ,  G01J3/433 ,  H01S3/105

CPC classification number: G01N21/39 ,  G01J3/021 ,  G01J3/10 ,  G01J3/42 ,  G01J3/427 ,  G01J3/433 ,  G01J2003/102 ,  G01N21/031 ,  G01N21/3504 ,  G01N2201/06113 ,  H01S3/08063 ,  H01S3/105

Abstract: Methods and optical detection systems (200, 300, 800, 900) for generating and processing a real-time time-domain cavity ringdown spectroscopy (CRDS) signal (831, 931) from an absorbing species in an optical detection system (200, 300, 800, 900) having an optical ringdown cavity (200, 300) are disclosed. The optical ringdown cavity (200, 300) is adapted for accepting a sample of an absorbing species. One or more modulated light signals (241,243,245,341) are generated using one or more light sources (240, 242, 244, 340). The light source(s) (240, 242, 244, 340) is pulsed at a specified pulse rate(s). The modulated light signal(s) (241,243,245, 341) is resonated using the optical ringdown cavity (200, 300) comprising a plurality of mirrors (220, 230), or sets of mirrors (320, 330), to produce the CRDS signal (831, 931). The reflectivity of the mirrors (220, 230), or sets of mirrors (320, 330), is dependent upon the pulse rate of the modulated light signals (241,243,245,341). Different beamlines (212, 214, 216, 312, 314, 316) are established by the modulated light signal(s) (241,243,245, 341) and the mirrors (220, 230, 320, 330) interacting with the absorbing species sample.

Abstract translation: 用于从光学检测系统（200,300）中的吸收物质生成和处理实时时域衰减光谱（CRDS）信号（831,931）的方法和光学检测系统（200,300,800,900） ，800,900），其具有光学衰减腔（200,300）。 光学衰减腔（200,300）适于接收吸收物质的样品。 使用一个或多个光源（240,242,244,340）产生一个或多个调制光信号（241,243,245,341）。 光源（240,242,244,340）以指定的脉冲速率脉冲。 调制光信号（241,243,245,341）使用包括多个反射镜（220,230）或一组反射镜（320,330）的光学环形空腔（200,300）进行谐振，以产生CRDS信号 （831,931）。 反射镜（220,230）或反射镜组（320,330）的反射率取决于调制光信号的脉冲速率（241,243,245,341）。 通过调制光信号（241,243,245,341）和与吸收物质样品相互作用的反射镜（220,230,320,330）建立不同的光束线（212,214,216,312,314,316）。

公开(公告)号：US20160116337A1

公开(公告)日：2016-04-28

申请号：US14985722

申请日：2015-12-31

Applicant: Pendar Technologies, LLC

Inventor： Mark F. Witinski ,  Laurent Diehl ,  Christian Pfluegl

IPC: G01J3/42 ,  G01J3/10

CPC classification number: G01J3/42 ,  G01J3/0208 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/10 ,  G01J2003/102

Abstract: A spectroscopy system includes an array of quantum cascade lasers (QCLs) that emits an array of non-coincident laser beams. A lens array coupled to the QCL array substantially collimates the laser beams, which propagate along parallel optical axes towards a sample. The beams remain substantially collimated over the lens array's working distance, but may diverge when propagating over longer distances. The collimated, parallel beams may be directed to/through the sample, which may be within a sample cell, flow cell, multipass spectroscopic absorption cell, or other suitable holder. Alternatively, the beams may be focused to a point on, near, or within the target using a telescope or other suitable optical element(s). When focused, however, the beams remain non-coincident; they simply intersect at the focal point. The target transmits, reflects, and/or scatters this incident light to a detector, which transduces the detected radiation into an electrical signal representative of the target's absorption or emission spectrum.

公开(公告)号：US20160109293A1

公开(公告)日：2016-04-21

申请号：US14894821

申请日：2014-05-15

Applicant: KONICA MINOLTA, INC.

Inventor： Shinichi Iida ,  Wataru Yamaguchi

IPC: G01J3/42 ,  G01J3/10 ,  G01J1/42 ,  G01J3/04

CPC classification number: G01J3/42 ,  G01J1/0271 ,  G01J1/1626 ,  G01J1/42 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/04 ,  G01J3/10 ,  G01J3/50 ,  G01J3/504 ,  G01J2001/1636 ,  G01J2003/425

Abstract: An illumination device is provided with a light source, a photodetector, and a support structure. The light source, which emits light, has light distribution in which a reference axis serves as an axis of symmetry or light distribution in which a plane including the reference axis serves as a plane of symmetry. A first light beam in the light is guided to the object to be illuminated. A second light beam in the light is guided to the photodetector. The photodetector detects intensity of the second light beam. The light source and the photodetector are supported by the support structure in positions and postures that allow the first light beam and the second light beam to be guided in an aforementioned manner. A traveling direction of the first light beam and a traveling direction of the second light beam make the same angle with the reference axis.

Abstract translation: 照明装置设置有光源，光电检测器和支撑结构。 发光的光源具有光分布，其中参考轴用作对称轴或光分布，其中包括基准轴的平面用作对称平面。 光中的第一光束被引导到被照明的物体。 光中的第二光束被引导到光电检测器。 光检测器检测第二光束的强度。 光源和光电检测器由支撑结构支撑在允许以上述方式引导第一光束和第二光束的位置和姿势。 第一光束的行进方向和第二光束的行进方向与参考轴线成相同的角度。

公开(公告)号：US20160103017A1

公开(公告)日：2016-04-14

申请号：US14513458

申请日：2014-10-14

Applicant: Henry H. Hung

Inventor： Henry H. Hung

IPC: G01J3/02 ,  G01L1/24 ,  G01K11/32 ,  G01J3/42

CPC classification number: G01J3/0218 ,  G01J3/0245 ,  G01J3/42 ,  G01J2003/2859 ,  G01J2003/425 ,  G01K11/3206 ,  G01L1/246

Abstract: Various implementations of an apparatus for sensing one or more parameters are disclosed herein. The apparatus includes a sweeping wavelength laser configured to generate a sweeping wavelength optical signal; an optical fiber including a Fiber Bragg Grating (FBG) structure configured to sense a parameter, wherein the optical fiber is configured to receive the sweeping wavelength optical signal, wherein the FBG structure is configured to produce a reflected optical signal with a particular wavelength in response to the sweeping wavelength optical signal, and wherein the particular wavelength varies as a function of the parameter; a photo detector configured to generate an electrical signal based on the reflected optical signal; a comparator configured to generate a pulse based on a comparison of the electrical signal to a threshold; and a processor configured to generate an indication of the parameter based on the pulse. The comparator may be configured as a Schmitt trigger.

Abstract translation: 本文公开了用于感测一个或多个参数的装置的各种实施方式。 该装置包括：扫描波长激光器，被配置为产生扫描波长光信号; 包括被配置为感测参数的光纤布拉格光栅（FBG）结构的光纤，其中所述光纤被配置为接收扫描波长光信号，其中所述FBG结构被配置为产生具有特定波长的反射光信号以作出响应 到所述扫描波长光信号，并且其中所述特定波长作为所述参数的函数而变化; 光检测器，被配置为基于所反射的光信号产生电信号; 比较器，被配置为基于电信号与阈值的比较来产生脉冲; 以及处理器，被配置为基于所述脉冲生成所述参数的指示。 比较器可以配置为施密特触发器。