公开(公告)号：US12117401B2

公开(公告)日：2024-10-15

申请号：US18455983

申请日：2023-08-25

Applicant: Foss Analytical A/S

Inventor： Daniel Aden ,  Ahmed Fadil

IPC: G01N21/71

CPC classification number: G01N21/718 ,  G01N2201/06113 ,  G01N2201/068 ,  G01N2201/126

Abstract: A LIBS analysis system comprises a focusing lens arrangement having a focal plane; a laser for propagating a laser beam through the focusing lens arrangement to be focused at the focal plane; a detector for generating an output that is proportional to an intensity of incident electromagnetic radiation that is incident on the detector; a translation mechanism configured to cause a relative movement of the sample holder and the focusing lens arrangement to vary a position of the focal plane along the optical path with respect to the sample holder; and a controller configured to automatically control the translation mechanism to cause the relative movement of the sample holder and the focusing lens arrangement to achieve an optimum position at which the focal plane and an analysis region of the upper surface intersecting the optical path are at or are close to coincidence.

公开(公告)号：US20240230417A1

公开(公告)日：2024-07-11

申请号：US18520254

申请日：2023-11-27

Applicant: Rebellion Photonics, Inc.

Inventor： Robert Timothy KESTER ,  Nathan Adrian HAGEN

IPC: G01J5/53 ,  G01J3/02 ,  G01J3/12 ,  G01J3/26 ,  G01J3/28 ,  G01J3/36 ,  G01J5/00 ,  G01J5/0802 ,  G01J5/0804 ,  G01J5/0806 ,  G01J5/20 ,  G01J5/80 ,  G01N21/17 ,  G01N21/3504 ,  H04N3/09 ,  H04N5/33 ,  H04N23/11 ,  H04N25/67 ,  H04N25/671 ,  H04N25/673

CPC classification number: G01J5/53 ,  G01J3/0208 ,  G01J3/0232 ,  G01J3/0256 ,  G01J3/0297 ,  G01J3/12 ,  G01J3/26 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/36 ,  G01J5/0014 ,  G01J5/0802 ,  G01J5/0804 ,  G01J5/0806 ,  G01J5/20 ,  G01N21/3504 ,  H04N3/09 ,  H04N5/33 ,  H04N23/11 ,  H04N25/67 ,  H04N25/671 ,  H04N25/673 ,  G01J2003/2826 ,  G01J2003/283 ,  G01J2005/0077 ,  G01J5/80 ,  G01N2021/1793 ,  G01N2021/3531 ,  G01N2201/06106 ,  G01N2201/068 ,  G01N2201/127

Abstract: Various embodiments disclosed herein describe a divided-aperture infrared spectral imaging (DAISI) system that is adapted to acquire multiple IR images of a scene with a single-shot (also referred to as a snapshot). The plurality of acquired images having different wavelength compositions that are obtained generally simultaneously. The system includes at least two optical channels that are spatially and spectrally different from one another. Each of the at least two optical channels are configured to transfer IR radiation incident on the optical system towards an optical FPA unit comprising at least two detector arrays disposed in the focal plane of two corresponding focusing lenses. The system further comprises at least one temperature reference source or surface that is used to dynamically calibrate the two detector arrays and compensate for a temperature difference between the two detector arrays.

公开(公告)号：US11953428B2

公开(公告)日：2024-04-09

申请号：US17077810

申请日：2020-10-22

Applicant: Quidel Corporation

Inventor： David Dickson Booker ,  Jhobe Steadman

IPC: G01N21/27 ,  G01N21/64

CPC classification number: G01N21/274 ,  G01N21/278 ,  G01N21/645 ,  G01N2201/068 ,  G01N2201/10 ,  G01N2201/12746 ,  G01N2201/12753 ,  G01N2201/12761

Abstract: Disclosed herein is a method for improving the precision of a test result from an instrument with an optical system that detects a signal. The method comprises including in the instrument a normalization target disposed directly or indirectly in the optical path of the optical system. Also disclosed are instruments comprising a normalization target, and systems comprising such an instrument and a test device that receives a sample suspected of containing an analyte.

公开(公告)号：US20240060907A1

公开(公告)日：2024-02-22

申请号：US18340394

申请日：2023-06-23

Applicant: Samsung Electronics Co., Ltd.

Inventor： Youngsun Choi ,  Soonyang Kwon ,  Kwangrak Kim ,  Jiwoong Kim ,  Jangryul Park ,  Myungjun Lee

IPC: G01N21/95 ,  G01N21/31

CPC classification number: G01N21/9501 ,  G01N21/31 ,  G01N2201/068 ,  G02B21/248

Abstract: In a focus control method of a spectroscopic measuring apparatus, the spectroscopic measuring apparatus having a first objective lens and a second objective lens equipped with a microsphere is provided. A sample is placed on a stage. A spectrum is obtained while moving the second objective lens vertically downward. A light intensity function that changes with a distance from a sample surface is obtained from the spectrum. A focal position of the second objective lens is determined from a threshold value of the light intensity function.

公开(公告)号：US11874221B2

公开(公告)日：2024-01-16

申请号：US17158717

申请日：2021-01-26

Applicant: Yokogawa Electric Corporation

Inventor： Anatoliy A. Kosterev

IPC: G01N21/31 ,  G01K11/00 ,  G01N21/64

CPC classification number: G01N21/3103 ,  G01K11/00 ,  G01N21/645 ,  G01N2021/6471 ,  G01N2201/068

Abstract: Methods and apparatus for analyzing optical measurements to determine whether a liquid includes dissolved oxygen, to determine a predicted concentration of the dissolved oxygen in the liquid, and/or to determine additional or alternative feature(s) related to dissolved oxygen in the liquid. An optical source can be controlled to emit optical radiation into a container that contains the liquid. The optical source can be located outside of the container, and the optical radiation includes (e.g., is restricted to) radiation that conforms to a dissolved oxygen absorption band. The optical radiation can be pulsed or can be periodically intensity modulated. A photodetector, located outside of the container but in optical communication with the interior of the container, can generate the optical measurements used in the analysis.

公开(公告)号：US11781990B2

公开(公告)日：2023-10-10

申请号：US17441910

申请日：2020-04-05

Applicant: Foss Analytical A/S

Inventor： Daniel Aden ,  Ahmed Fadil

IPC: G01N21/71

CPC classification number: G01N21/718 ,  G01N2201/068 ,  G01N2201/06113 ,  G01N2201/126

Abstract: A LIBS analysis system comprises a focusing lens arrangement having a focal plane; a laser for propagating a laser beam through the focusing lens arrangement to be focused at the focal plane; a detector for generating an output that is proportional to an intensity of incident electromagnetic radiation that is incident on the detector; a translation mechanism configured to cause a relative movement of the sample holder and the focusing lens arrangement to vary a position of the focal plane along the optical path with respect to the sample holder; and a controller configured to automatically control the translation mechanism to cause the relative movement of the sample holder and the focusing lens arrangement to achieve an optimum position at which the focal plane and an analysis region of the upper surface intersecting the optical path are at or are close to coincidence.

公开(公告)号：US11709129B2

公开(公告)日：2023-07-25

申请号：US17304928

申请日：2021-06-28

Applicant: COR HEALTH, INC.

Inventor： Robert G. Messerschmidt

IPC: G01N21/27 ,  G01N21/35 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/026 ,  A61B5/145 ,  G01N21/33 ,  G01N21/65 ,  G01N33/49 ,  A61B5/20

CPC classification number: G01N21/27 ,  A61B5/0075 ,  A61B5/0261 ,  A61B5/1455 ,  A61B5/14507 ,  G01N21/33 ,  G01N21/35 ,  G01N21/65 ,  G01N33/49 ,  A61B5/208 ,  A61B2562/046 ,  G01N2201/068 ,  G01N2201/06113

Abstract: A measurement apparatus comprises optical components arranged to provide parallel measurements of a biological sample. The parallel sample measurements provide improved accuracy with lower detection limit thresholds. The parallel measurements may comprise one or more of Raman spectroscopy measurements or infrared spectroscopy measurements. The parallel measurements can be combined with a light source. In many embodiments, the light source comprises one or more wavelengths corresponding to resonance frequencies of one or more molecules of the sample, such as wavelengths of ultraviolet light. The wavelengths of light corresponding to resonance frequencies can provide an increased signal to noise ratio. The parallel array optical configuration can be combined with wavelengths of light corresponding to resonance frequencies in order to provide increased measurement accuracy and detection of metabolites.

公开(公告)号：US20230213447A1

公开(公告)日：2023-07-06

申请号：US18121577

申请日：2023-03-14

Applicant: Gemological Institute of America, Inc. (GIA)

Inventor： Hiroshi TAKAHASHI

IPC: G01N21/64 ,  G01N33/38 ,  G01N21/87

CPC classification number: G01N21/6456 ,  G01N33/381 ,  G01N21/87 ,  G01N2201/0634 ,  G01N2021/6471 ,  G01N2201/062 ,  G01N2201/068 ,  G01N2201/12

Abstract: Provided herein is an apparatus for assessing a fluorescence characteristic of a gemstone. The apparatus comprises an optically opaque platform for supporting a gemstone to be assessed, one or more light source to provide uniform UV and non-UV illumination, an image capturing component, and a telecentric lens positioned to provide fluorescent images of the illuminated gemstone to the image capturing component. Also provided are methods of fluorescence analysis based on images collected using such an apparatus.

公开(公告)号：US11674960B2

公开(公告)日：2023-06-13

申请号：US17344870

申请日：2021-06-10

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Axel Scherer ,  Samuel Njoroge ,  Jingqing Huang

IPC: G01N33/543 ,  G01N33/566 ,  A61B5/1459 ,  G01N21/41 ,  G01N33/552 ,  A61B5/1491

CPC classification number: G01N33/566 ,  A61B5/1459 ,  G01N21/41 ,  G01N33/54373 ,  G01N33/552 ,  A61B5/1491 ,  A61B2562/0233 ,  A61B2562/043 ,  G01N2201/068 ,  G01N2201/08

Abstract: An implantable diagnostic device in accordance with the present disclosure provides various benefits such as a compact size thereby allowing implanting of the device inside animate objects; low cost due to incorporation of inexpensive detection circuitry and the use of conventional IC fabrication techniques; re-usability by heating thereby allowing multiple diagnostic tests to be performed without discarding the device; and a configuration that allows performing of simultaneous and/or sequential diagnostic tests for detecting one or more similar or dissimilar target molecules concurrently or at different times.

公开(公告)号：US20230174122A1

公开(公告)日：2023-06-08

申请号：US18104497

申请日：2023-02-01

Applicant: Ensco, Inc.

Inventor： Anthony Kim ,  David G. Ford ,  Jeffrey Bloom

IPC: B61K9/08 ,  B61L23/04 ,  E05F15/70 ,  G01N21/55 ,  G02B7/182 ,  G01N21/95

CPC classification number: B61K9/08 ,  B61L23/042 ,  B61L23/041 ,  E05F15/70 ,  G01N21/55 ,  G02B7/182 ,  G01N21/95 ,  G01N2201/068 ,  E05Y2900/51 ,  G01N2201/0216

Abstract: A deployable measurement system for analyzing a rail of a railroad track includes a housing, a reflecting assembly coupled to the housing, a movement assembly coupled to the housing, and an optical measurement system disposed within the housing. Both the housing and the reflecting assembly are moveable between a stored position and a deployed position. The movement assembly includes a deployment assembly that moves the reflecting assembly from the stored position to the deployed position, and a retraction assembly that moves the reflecting assembly from the deployed position to the stored position. The optical measurement system emits and receives light. The reflecting assembly reflects the emitted light toward the rail. The reflecting assembly reflects light reflected off of the rail toward the optical measurement system. The light received by the optical measurement system is used to measure parameters related to the rail.