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公开(公告)号：CA3094700A1
公开(公告)日：2019-10-03
申请号：CA3094700
申请日：2019-03-27
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , AMEDZO LUKIANA , BABU SURESH , BAIAZITOV RAMIL Y , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MSZAR NICHOLAS W , NARASIMHAN JANA , PAL SUDIPTA , PATEL JIGAR S , TURPOFF ANTHONY , WOLL MATHEW G , XU ZHENRONG , ZHANG NANJING , ALAM RAUFUL
IPC: A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：CA3119019A1
公开(公告)日：2017-06-15
申请号：CA3119019
申请日：2016-12-11
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: C07D401/14 , A61K31/501 , A61P25/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：SI3814357T1
公开(公告)日：2024-09-30
申请号：SI201930785
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/00 , A61K31/00 , A61P25/00 , C07D491/00 , C07D495/00 , C07D519/00
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公开(公告)号：LT3814357T
公开(公告)日：2024-06-25
申请号：LTUS2019038889
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
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公开(公告)号：PE20240929A1
公开(公告)日：2024-04-30
申请号：PE2024000170
申请日：2022-07-29
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , ALAM RAUFUL , BHATTACHARYYA ANURADHA , CHEN GUANGMING , EASTWOOD MATTHEW S , HOSSEYNI SEYEDMORTEZA , JIANG YAO , KARP GARY MITCHELL , MOON YOUNG-CHOON , NARASIMHAN JANA , REN HONGYU , SYDORENKO NADIYA , WOLL MATTHEW G , ZHANG NANJING
IPC: C07D487/04 , A61K31/5025 , A61P25/14 , A61P25/28
Abstract: La presente invencion se refiere a compuestos de heteroarilo biciclicos sustituidos, formas y composiciones farmaceuticas de los mismos y metodos de uso de dichos compuestos, formas o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington. En particular, se refiere a un compuesto de Formula (Ib) o una forma del mismo, en donde: RA es (a), (b), (c) y (d) cada uno de RA1 y RA2 se selecciona independientemente entre H, deuterio, halogeno, entre otros; y, cada uno de RB1 y RB2 se selecciona independientemente entre H, deuterio, halogeno, entre otros; en donde la forma del compuesto es una forma de sal del mismo.
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Patent Agency Ranking
公开(公告)号：AU2022320725A1
公开(公告)日：2024-02-22
申请号：AU2022320725
申请日：2022-07-29
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , ALAM RAUFUL , BHATTACHARYYA ANURADHA , CHEN GUANGMING , EASTWOOD MATTHEW , HOSSEYNI SEYEDMORTEZA , JIANG YAO , KARP GARY , MOON YOUNG-CHOON , NARASIMHAN JANA , REN HONGYU , SYDORENKO NADIYA , WOLL MATTHEW , ZHANG NANJING
IPC: C07D487/04 , A61K31/5025 , A61P25/14 , A61P25/28
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：CA3007412C
公开(公告)日：2021-08-24
申请号：CA3007412
申请日：2016-12-11
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: C07D401/14 , A61K31/454 , A61K31/501 , A61K31/517 , A61K31/55 , A61P21/00 , A61P25/14 , A61P25/28 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/10 , C07D487/08 , C07D487/10
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：CO2020016285A2
公开(公告)日：2021-01-18
申请号：CO2020016285
申请日：2020-12-24
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
Abstract: La presente descripción se refiere a compuestos, formas y composiciones farmacéuticas de los mismos y a métodos de uso de dichos compuestos, formas o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington. Fórmula (i). En particular, la presente descripción se refiere a compuestos heterocíclicos y de heteroarilo sustituidos de Fórmula (I), formas y composiciones farmacéuticas de los mismos y a métodos de uso de dichos compuestos, formas o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington.
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公开(公告)号：MX2020009956A
公开(公告)日：2021-01-15
申请号：MX2020009956
申请日：2019-03-27
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW G , NARASIMHAN JANA , ZHANG NANJING , KARP GARY MITCHELL , SYDORENKO NADIYA , BABU SURESH , BHATTACHARYYA ANURADHA , BARRAZA SCOTT J , MAZZOTTI ANTHONY R , TURPOFF ANTHONY , XU ZHENRONG , MOON YOUNG-CHOON , PATEL JIGAR S , ALAM MD RAUFUL , AMEDZO LUKIANA , BAIAZITOV RAMIL Y , KENTON NATHANIEL T , MSZAR NICHOLAS W , PAL SUDIPTA
IPC: A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
Abstract: La descripción actual se refiere a compuestos, formas, y composiciones farmacéuticas de los mismos y métodos para usar tales compuestos, formas, o composiciones de los mismos para el tratamiento o aminoración de la enfermedad de Huntington. (ver Fórmulas) En particular, la descripción actual se refiere a compuestos heteroarilo monocíclicos sustituidos de la Fórmula (I) o Fórmula (II), formas y composiciones farmacéuticas de los mismos y métodos para usar tales compuestos, formas, o composiciones de los mismos para el tratamiento o aminoración de la enfermedad de Hungtinton.
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公开(公告)号：CA3139821A1
公开(公告)日：2020-11-19
申请号：CA3139821
申请日：2020-05-12
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , AMEDZO LUKIANA , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , LUONG TOM TUAN , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MORRILL CHRISTIE , MSZAR NICHOLAS WALTER , NARASIMHAN JANA , PATEL JIGAR S , REN HONGYU , TURPOFF ANTHONY , WANG GANG , WOLL MATTHEW G , ZHANG NANJING , ZHANG XIAOYAN
IPC: C07D401/14 , A61K31/501 , A61K31/53 , A61P25/28 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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