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公开(公告)号：CA2737031A1
公开(公告)日：2010-04-01
申请号：CA2737031
申请日：2009-09-28
Applicant: ABBOTT LAB
Inventor： LEE CHIH-HUNG , LI TAO , GFESSER GREGORY A , FAGHIH RAMIN , BUNNELLE WILLIAM H , SCANIO MARC , SHI LEI , GOPALAKRISHNAN MURALI , DONNELLY-ROBERTS DIANA , HU MIN , SCHRIMPF MICHAEL R , MORTELL KATHLEEN H , NERSESIAN DIANA L , SIPPY KEVIN B
IPC: C07D487/18 , A61K31/33 , A61P25/00 , C07D471/08 , C12Q1/02
Abstract: The present application relates to indole and indoline derivatives of formula (I), (II), (III), (IV), (V), or (VI) wherein a, R1, R2, R3, R4, R5, U, V, W, X, Y, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.
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公开(公告)号：DE60130460T2
公开(公告)日：2008-06-05
申请号：DE60130460
申请日：2001-07-11
Applicant: ABBOTT LAB
Inventor： BENNANI YOUSSEF L , FAGHIH RAMIN , DWIGHT WESLEY J , VASUDEVAN ANIL , CONNER SCOTT E
IPC: C07D207/12 , C07D295/08 , A61K31/40 , A61K31/4025 , A61K31/4178 , A61K31/427 , A61K31/443 , A61K31/4439 , A61K31/455 , A61K31/4709 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/5377 , A61P3/04 , A61P9/10 , A61P11/06 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D207/06 , C07D207/14 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
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公开(公告)号：ES2292603T3
公开(公告)日：2008-03-16
申请号：ES01952653
申请日：2001-07-11
Applicant: ABBOTT LAB
Inventor： BENNANI YOUSSEF L , FAGHIH RAMIN , DWIGHT WESLEY J , VASUDEVAN ANIL , CONNER SCOTT E
IPC: C07D207/12 , C07D295/08 , A61K31/40 , A61K31/4025 , A61K31/4178 , A61K31/427 , A61K31/443 , A61K31/4439 , A61K31/455 , A61K31/4709 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/5377 , A61P3/04 , A61P9/10 , A61P11/06 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D207/06 , C07D207/14 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
Abstract: Un compuesto de fórmula I o una sal farmacéuticamente aceptable del mismo, donde Z se selecciona del grupo que consiste en un enlace covalente y CH2; R1 se selecciona del grupo que consiste en OR2, NR3R4 y R2 se selecciona del grupo que consiste en hidrógeno, alcoxicarbonilo, alquilo, alquilcarbonilo, aminocarbonilo, sulfono y fosfono.
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公开(公告)号：CA2647601A1
公开(公告)日：2008-01-03
申请号：CA2647601
申请日：2007-06-27
Applicant: ABBOTT LAB
Inventor： GOPALAKRISHNAN MURALI , GOPALAKRISHNAN SUJATHA , MALYSZ JOHN , LYNCH CHRISTOPHER L , GUBBINS EARL J , EL KOUHEN RACHID , LI JINHE , FAGHIH RAMIN , GFESSER GREGORY A
IPC: C07D207/34 , A61K31/402 , A61P25/00 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10
Abstract: The invention relates to a series of substituted pyrrole derivatives, compositions comprising the same, and methods of treating conditions and disorders using such compounds and compositions.
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公开(公告)号：CA2505427A1
公开(公告)日：2004-05-27
申请号：CA2505427
申请日：2003-11-05
Applicant: ABBOTT LAB
Inventor： LIU HUAQING , LUKIN KIRILL A , NERSESIAN DIANA L , PU YU-MING , SHARMA PADAM N , BLACK LAWRENCE A , BENNANI YOUSSEF L , CHANG SOU-JEN , CURTIS MICHAEL P , ALTENBACH ROBERT J , COWART MARLON D , GFESSER GREGORY A , FAGHIH RAMIN , KU YI-YIN
IPC: A61P3/00 , A61P25/00 , C07C255/58 , C07D207/08 , C07D207/12 , C07D207/14 , C07D207/20 , C07D213/30 , C07D213/38 , C07D213/61 , C07D213/64 , C07D213/85 , C07D215/12 , C07D215/14 , C07D215/20 , C07D217/14 , C07D237/12 , C07D237/14 , C07D237/28 , C07D239/26 , C07D239/28 , C07D239/42 , C07D239/52 , C07D241/12 , C07D241/42 , C07D263/32 , C07D277/28 , C07D295/073 , C07D295/092 , C07D295/096 , C07D295/112 , C07D295/135 , C07D295/155 , C07D401/04 , C07D401/10 , C07D403/04 , C07D403/10 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D471/04 , A61K31/40 , C07D261/08 , C07D295/088 , C07D295/116
Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for prepari ng compounds within the scope of formula (I).
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Patent Agency Ranking
公开(公告)号：UY27212A1
公开(公告)日：2002-10-31
申请号：UY27212
申请日：2002-03-15
Applicant: ABBOTT LAB
Inventor： BENNANI YOUSSEF L , COWART MARLON D , GFESSER GREGORY A , BLACK LAWRENCE A , FAGHIH RAMIN
IPC: C07D307/77
Abstract: Los compuestos de fórmula (I) o una sal aceptable para uso farmacéutico, éster, amida o prodroga del mismo, son útiles para la modulación de los receptores de histamina-3 en mamíferos y son útiles para el tratamiento de afecciones que se alivian por administración de ligandos del receptor de histamina-3
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公开(公告)号：ES2115760T3
公开(公告)日：1998-07-01
申请号：ES93904533
申请日：1993-01-19
Applicant: ABBOTT LAB
Inventor： LARTEY PAUL A , NELLANS HUGH N , KLEIN LARRY L , FAGHIH RAMIN
IPC: A61K31/70 , A61K31/7042 , A61K31/7048 , A61P1/00 , A61P1/08 , A61P1/10 , A61P31/04 , C07D233/22 , C07H17/08
Abstract: 4''-Deoxy derivatives of erythromycin having the Formula (I) (I) and pharmaceutically acceptable salts thereof, which are enhancers of gastric motility but have minimal antibacterial activity, as well as pharmaceutical compositions containing the same and methods for their use and preparation.
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公开(公告)号：AT164848T
公开(公告)日：1998-04-15
申请号：AT93904533
申请日：1993-01-19
Applicant: ABBOTT LAB
Inventor： LARTEY PAUL A , NELLANS HUGH N , KLEIN LARRY L , FAGHIH RAMIN
IPC: A61K31/70 , A61K31/7042 , A61K31/7048 , A61P1/00 , A61P1/08 , A61P1/10 , A61P31/04 , C07D233/22 , C07H17/08
Abstract: 4''-Deoxy derivatives of erythromycin having the Formula (I) (I) and pharmaceutically acceptable salts thereof, which are enhancers of gastric motility but have minimal antibacterial activity, as well as pharmaceutical compositions containing the same and methods for their use and preparation.
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公开(公告)号：ZA951845B
公开(公告)日：1996-03-15
申请号：ZA951845
申请日：1995-03-06
Applicant: ABBOTT LAB
Inventor： FAGHIH RAMIN , LARTEY PAUL A
IPC: A61K20060101 , A61K
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公开(公告)号：ZA9501845B
公开(公告)日：1996-03-15
申请号：ZA9501845
申请日：1995-03-06
Applicant: ABBOTT LAB
Inventor： FAGHIH RAMIN , LARTEY PAUL A
IPC: A61K20060101 , A61K
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