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公开(公告)号：WO2009067578A3
公开(公告)日：2009-11-26
申请号：PCT/US2008084142
申请日：2008-11-20
Applicant: ABBOTT LAB , VON GELDERN THOMAS W , BURKALOW JUFANG H , BARNES DAVID M , HAIGHT ANGHONY R , HENGEVELD JOHN E , LI XIAOFENG , MCLAUGHLIN MAUREEN A , NOONAN WILLIAM T , PEI ZHONGHUA , WU-WONG JINSHYUN RUTH
Inventor： VON GELDERN THOMAS W , BURKALOW JUFANG H , BARNES DAVID M , HAIGHT ANGHONY R , HENGEVELD JOHN E , LI XIAOFENG , MCLAUGHLIN MAUREEN A , NOONAN WILLIAM T , PEI ZHONGHUA , WU-WONG JINSHYUN RUTH
IPC: C07C401/00
CPC classification number: C07C401/00 , C07C2601/14 , C07C2602/24
Abstract: The invention relates to compounds that are vitamin D receptor activators, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.
Abstract translation: 本发明涉及作为维生素D受体激活剂的化合物，包含此类化合物的组合物，使用此类化合物和组合物的方法，制备此类化合物的方法以及在此类过程中获得的中间体。
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公开(公告)号：BRPI0816994A2
公开(公告)日：2015-03-24
申请号：BRPI0816994
申请日：2008-09-17
Applicant: ABBOTT LAB
Inventor： ROLF WAGNER , TUFANO MICHAEL D , STEWART KENT D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , CHEN SHUANG , FRANCZYK THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , ZHANG GEOFF G Z
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10 , C07D417/10
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公开(公告)号：NZ584720A
公开(公告)日：2012-07-27
申请号：NZ58472008
申请日：2008-09-17
Applicant: ABBOTT LAB
Inventor： FRANCZYK THADDEUS S , WAGNER ROLF , TUFANO MICHAEL D , STEWART KENT D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , CHEN SHUANG , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , ZHANG GEOFF G
IPC: C07D417/10 , A61K31/513 , A61P31/12 , C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10
Abstract: Disclosed are Uracil or Thymine derivatives of formula (I) examples of which are: (E)-N-(4-(3-tert-butyl-5-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide; (E)-N-(4-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide (Z)-N-(4-(2-(3-tert-butyl-5-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-2-methoxyphenyl)-1-chlorovinyl)phenyl)methanesulfonamide; (E)-1-(3-tert-butyl-5-(4-fluorostyryl)-4-methoxyphenyl) dihydropyrimidine-2,4(1H,3H)-dione; The compounds are for use in treating Hepatitis C
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公开(公告)号：DK2203431T3
公开(公告)日：2011-11-21
申请号：DK08832330
申请日：2008-09-17
Applicant: ABBOTT LAB
Inventor： FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , BETEBENNER DAVID A , DEGOEY DAVID A , DONNER PAMELA L , KATI WARREN M , KRUEGER ALLAN C , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , MOTTER CHRISTOPHER E , PRATT JOHN K , RANDOLPH JOHN T , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , BARNES DAVID M , CHEN SHUANG , FRANCZYK THADDEUS S II , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10
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公开(公告)号：SI2203430T1
公开(公告)日：2011-10-28
申请号：SI200830377
申请日：2008-09-17
Applicant: ABBOTT LAB
Inventor： DONNER PAMELA L , RANDOLPH JOHN T , KRUEGER ALLAN C , BETEBENNER DAVID A , HUTCHINSON DOUGLAS K , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , PRATT JOHN K , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z
IPC: C07D239/00 , A61K31/506 , A61K31/513 , A61P31/00 , C07D401/00 , C07D403/00 , C07D405/00 , C07D409/00 , C07D413/00
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Patent Agency Ranking
公开(公告)号：AT512954T
公开(公告)日：2011-07-15
申请号：AT08831558
申请日：2008-09-17
Applicant: ABBOTT LAB
Inventor： DONNER PAMELA L , RANDOLPH JOHN T , KRUEGER ALLAN C , BETEBENNER DAVID A , HUTCHINSON DOUGLAS K , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , PRATT JOHN K , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z
IPC: C07D239/22 , C07D239/54 , C07D239/553 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10
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公开(公告)号：DOP2010000084A
公开(公告)日：2010-06-15
申请号：DO2010000084
申请日：2010-03-16
Applicant: ABBOTT LAB
Inventor： STEWART KENT D , ZHANG GEOFF G Z , CHEN SHUANG , HENRY RODGER F , WAGNER ROLF , TUFANO MICHAEL D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , II TRADDEUS S FRANCZYK , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY
IPC: C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10 , C07D417/10
Abstract: Esta invención se relaciona con: (a) compuestos y sales de los mismos que, entre otros, inhiben el HCV; (b) intermediarios de utilidad para la preparación de dichos compuestos y sales; (c) composiciones que comprenden dichos compuestos y sales; (d) metodos para preparar dichos intermediarios, compuestos, sales y composiciones; (e) metodos de use de dichos compuestos, sales y composiciones; y (f) conjuntos de elementos que comprenden dichos compuestos, sales y composiciones.
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公开(公告)号：AU2008302448A1
公开(公告)日：2009-03-26
申请号：AU2008302448
申请日：2008-09-17
Applicant: ABBOTT LAB
Inventor： HAIGHT ANTHONY R , RANDOLPH JOHN T , LONGENECKER KENTON L , FRANCZYK THADDEUS S II , BETEBENNER DAVID A , DEGOEY DAVID A , STEWART KENT D , TUFANO MICHAEL D , LIU YAYA , WAGNER ROLF , SARRIS KATHY , LIU DACHUN , BARNES DAVID M , ROCKWAY TODD W , FLENTGE CHARLES A , KATI WARREN M , KOTECKI BRIAN J , ZHANG GEOFF G Z , CHEN SHUANG , GAO YI , HENRY RODGER F , HUANG PEGGY P , PRATT JOHN K , DONNER PAMELA L , MARING CLARENCE J , HUTCHINSON DOUGLAS K , KRUEGER ALLAN C , LOU XIAOCHUN , MOTTER CHRISTOPHER E , HENGEVELD JOHN E
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10 , C07D417/10
Abstract: This invention relates to: (a) compounds and salts thereof that, inter alia , inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; and (e) use of such compounds, salts, and compositions.
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公开(公告)号：AT263180T
公开(公告)日：2004-04-15
申请号：AT98958010
申请日：1998-11-17
Applicant: ABBOTT LAB
Inventor： HENGEVELD JOHN E , DONG XIAOXING , GUPTA ASHOK K , COPP RICHARD R JR , PREMCHANDRAN RAMIYA H
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08
Abstract: Disclosed is an improved and efficient process for N-desmethylating the 3'-amino nitrogen of erythromycins and for converting the 3'-N-desmethylated erythromycins into 3'-N-substituted derivatives of 8,9-anhydro-erythromycin 6,9-hemiketals.
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公开(公告)号：BRPI0820043A2
公开(公告)日：2015-05-12
申请号：BRPI0820043
申请日：2008-11-20
Applicant: ABBOTT LAB
Inventor： GELDERN THOMAS W VON , BARKALOW JUFANG H , BARNES DAVID M , HAIGHT ANTHONY R , HENGEVELD JOHN E , LI XIAOFENG , MCLAUGHLIN MAUREEN A , NOONAN WILLIAM T , PEI ZHONGHUA , WU-WONG JINSHYUN RUTH
IPC: C07C401/00
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