-
公开(公告)号：CA2356320A1
公开(公告)日：2000-07-06
申请号：CA2356320
申请日：1999-12-29
Applicant: ABBOTT LAB
Inventor： LINK JAMES , PEI ZHONGHUA , GUNAWARDANA INDRANI W , LIU GANG , FREEMAN JENNIFER C , ZHU GUI-DONG , BOYD STEVEN A , JAE HWAN-SOO , XIN ZHILI , WINN MARTIN , LYNCH JOHN K , VON GELDERN TOM , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10 , A61K31/10 , C07D295/20 , A61K31/33
Abstract: The present invention relates to novel cinnamide compounds that are useful f or treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
-
公开(公告)号：SK75999A3
公开(公告)日：2000-05-16
申请号：SK75999
申请日：1997-12-10
Applicant: ABBOTT LAB
Inventor： HOLLADAY MARK W , ARNERIC STEPHEN P , BAI HAO , DART MICHAEL J , LIN NAN-HORNG , LYNCH JOHN K , OR YAT SUN , RYTHER KEITH B , SULLIVAN JAMES P , WASICAK JAMES T , EHRLICH PAUL P
IPC: A61P25/04 , A61K31/4427 , A61K31/443 , A61K31/4439 , A61K31/485 , A61P25/28 , A61P29/00 , C07D205/04 , C07D401/12 , C07D401/14 , C07D405/14 , A61K31/44
Abstract: The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula (I) or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula (I) which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.
-
公开(公告)号：TR199901904T2
公开(公告)日：1999-10-21
申请号：TR9901904
申请日：1997-12-10
Applicant: ABBOTT LAB
Inventor： HOLLADAY MARK W , ARNERIC STEPHEN P , BAI HAO , DART MICHAEL J , LIN NAN-HORNG , LYNCH JOHN K , OR YAT SUN , RYTHER KEITH B , SULLIVAN JAMES P , WASICAK JAMES T , EHRLICH PAUL P
IPC: A61P25/04 , A61K31/4427 , A61K31/443 , A61K31/4439 , A61K31/485 , A61P25/28 , A61P29/00 , C07D205/04 , C07D401/12 , C07D401/14 , C07D405/14 , A61K31/44
Abstract: The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula (I) or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula (I) which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.
-
公开(公告)号：NO992705L
公开(公告)日：1999-08-03
申请号：NO992705
申请日：1999-06-03
Applicant: ABBOTT LAB
Inventor： HOLLADAY MARK W , ARNERIC STEPHEN P , BAI HAO , DART MICHAEL J , LIN NAN-HORNG , LYNCH JOHN K , OR YAT SUN , RYTHER KEITH B , SULLIVAN JAMES P , WASICAK JAMES T , EHRLICH PAUL P
IPC: A61P25/04 , A61K31/4427 , A61K31/443 , A61K31/4439 , A61K31/485 , A61P25/28 , A61P29/00 , C07D205/04 , C07D401/12 , C07D401/14 , C07D405/14 , A61K31/44
Abstract: The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula (I) or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula (I) which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.
-
55.发明专利
公开(公告)号：CA2315117A1
公开(公告)日：1999-07-01
申请号：CA2315117
申请日：1998-12-18
Applicant: ABBOTT LAB
Inventor： HE YUN , LEBOLD SUZANNE A , ELLIOTT RICHARD L , BAI HAO , DART MICHAEL J , WASICAK JAMES T , KINCAID JOHN F , GARVEY DAVID S , LI YIHONG , RYTHER KEITH , HOLLADAY MARK W , EHRLICH PAUL P , ABREO MELWYN A , GUNN DAVID E , LIN NAN-HORNG , SCHKERYANTZ JEFFREY M , LYNCH JOHN K
IPC: A61K31/427 , A61K31/4427 , A61K31/4439 , A61K31/4545 , A61K31/4709 , A61K31/4725 , A61K31/497 , A61K31/501 , A61K31/506 , A61P25/00 , A61P25/22 , A61P25/28 , A61P25/30 , A61P43/00 , C07D401/12 , C07D403/12 , C07D417/12 , C07D455/02 , C07D487/04 , A61K31/40 , A61K31/425 , A61K31/44 , A61K31/47 , A61K31/50 , A61K31/505
Abstract: Novel compounds having formulas (I), (II) or (III) or pharmaceuticallyacceptable salts or prodrugs thereof, which are useful for controlling synaptic transmission; to therapeutically-effective pharmaceutical compositions of these compounds; and to the use of said compositions to controlling synaptic transmission in human or veterinary patients.
-
Patent Agency Ranking
公开(公告)号：IS2125B
公开(公告)日：2006-07-14
申请号：IS6097
申请日：2001-09-28
Applicant: ABBOTT LAB
Inventor： JAMES LINK , GANG LIU , ZHONGHUA PEI , VON GELDERN THOMAS W , MARTIN WINN , ZHILI XIN , SHELDON WANG , BOYD STEVEN A , GUI-DONG ZHU , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A , HWAN-SOO JAE , LYNCH JOHN K
IPC: C07C323/62 , C07D243/08 , A61K20060101 , A61K31/00 , A61K31/10 , A61K31/165 , A61K31/33 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/472 , A61K31/496 , A61K31/4965 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61K31/55 , A61K31/551 , A61P20060101 , A61P29/00 , A61P37/06 , C07C20060101 , C07C323/60 , C07D20060101 , C07D205/04 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/26 , C07D207/27 , C07D207/273 , C07D209/08 , C07D209/12 , C07D211/20 , C07D211/22 , C07D211/46 , C07D211/60 , C07D211/62 , C07D211/64 , C07D211/66 , C07D211/70 , C07D213/40 , C07D213/74 , C07D213/81 , C07D215/24 , C07D217/02 , C07D217/04 , C07D217/06 , C07D233/61 , C07D239/42 , C07D241/04 , C07D241/24 , C07D257/04 , C07D279/12 , C07D295/18 , C07D295/185 , C07D295/20 , C07D295/205 , C07D295/22 , C07D295/26 , C07D307/24 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/66 , C07D319/18 , C07D401/04 , C07D401/12 , C07D405/12 , C07D417/12 , C07D471/20 , C07D487/04 , C07D491/113 , C07D521/00
Abstract: The present invention relates to cinnamide compounds of formula (I), in which at least one of R1 to R5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims, that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal.
-
57.发明专利
公开(公告)号：CZ296726B6
公开(公告)日：2006-05-17
申请号：CZ20012412
申请日：1999-12-29
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , VON GELDERN TOM , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A
IPC: C07C323/62 , C07D295/12 , A61K31/095 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/33 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/00 , A61P37/02 , C07C323/00 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D209/30 , C07D209/38 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D239/88 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/20 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D311/22 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10
Abstract: Predlozené resení se týká urcitých aryl - nebo heteroarylthiofenylcinnamidu, tedy sloucenin na báziamidu kyseliny skoricové, obec. vzorce I, kde alespon jedna ze skupin R.sub.1.n. nebo R.sub.3.n. jsou cis-cinnamid vzorce a nebo trans-cinnamid vzorce b, které jsou vhodné pro lécení zánetlivých a imunních onemocnení, farmaceutických prostredku obsahujících tyto slouceniny. Dále se týká zpusobu výroby techto sloucenin a jejich pouzití pro výrobu léciv.
-
公开(公告)号：HRP20010512B1
公开(公告)日：2006-02-28
申请号：HRP20010512
申请日：2001-07-10
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , GELDERN TOM VON , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A
IPC: C07C323/62 , C07D295/12 , A61K31/10 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/33 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/20 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10
Abstract: The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
-
公开(公告)号：GEP20053657B
公开(公告)日：2005-11-10
申请号：GEAP2000004605
申请日：2000-04-03
Applicant: ABBOTT LAB
Inventor： JAE WOO PARK , LINK JAMES , LIU GANG , PEI ZHONGHUA , VON GELDERN TOM , WINN MARTIN , XIN ZHILI , WANG SHELDON , BOYD STEVEN A , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA ; INDRANI W , STAEGER MICHAEL A , JAE HWAN-SOO , LYNCH JOHN K
IPC: C07C323/62 , C07D243/08 , A61K20060101 , A61K31/10 , A61K31/165 , A61K31/33 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/472 , A61K31/496 , A61K31/4965 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61K31/55 , A61K31/551 , A61P20060101 , A61P29/00 , A61P37/06 , C07C20060101 , C07C323/60 , C07D20060101 , C07D205/04 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/26 , C07D207/27 , C07D207/273 , C07D209/08 , C07D209/12 , C07D211/20 , C07D211/22 , C07D211/46 , C07D211/60 , C07D211/62 , C07D211/64 , C07D211/66 , C07D211/70 , C07D213/40 , C07D213/74 , C07D213/81 , C07D215/24 , C07D217/02 , C07D217/04 , C07D217/06 , C07D233/61 , C07D239/42 , C07D241/04 , C07D241/24 , C07D257/04 , C07D279/12 , C07D295/18 , C07D295/185 , C07D295/20 , C07D295/205 , C07D295/22 , C07D295/26 , C07D307/24 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/66 , C07D319/18 , C07D401/04 , C07D401/12 , C07D405/12 , C07D417/12 , C07D471/20 , C07D487/04 , C07D491/113 , C07D521/00
Abstract: 1. Technical Result Increase in treatment efficiency of inflamma¬tory and immune diseases. 2. Essence The present invention relates to compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal. 3. Field of Application Medicine.
-
公开(公告)号：EA005207B1
公开(公告)日：2004-12-30
申请号：EA200100732
申请日：1999-12-29
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , VON GELDERN TOM , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10 , C07D295/20 , A61K31/10 , A61K31/33 , A61P37/06
Abstract: Настоящееизобретениеотноситсяк новымциннамиднымсоединениям, которыемогутбытьиспользованыдлялечениявоспалительныхи иммунныхзаболеваний, кфармацевтическимкомпозициям, содержащимданныесоединения, ик способамингибированиявоспаленияилиподавленияиммунногоответау млекопитающих.
-
-
-
-
-
-
-
-
-
Search Results
93
records
(took 0.024 seconds)
