Systems and methods for selective detection and imaging in coherent Raman microscopy by spectral excitation shaping
    121.
    发明授权
    Systems and methods for selective detection and imaging in coherent Raman microscopy by spectral excitation shaping 有权
    通过光谱激发成形在相干拉曼显微镜中进行选择性检测和成像的系统和方法

    公开(公告)号:US09285575B2

    公开(公告)日:2016-03-15

    申请号:US12690579

    申请日:2010-01-20

    Abstract: A microscopy imaging system is disclosed that includes a light source system, a spectral shaper, a modulator system, an optics system, an optical detector and a processor. The light source system is for providing a first train of pulses and a second train of pulses. The spectral shaper is for spectrally modifying an optical property of at least some frequency components of the broadband range of frequency components such that the broadband range of frequency components is shaped producing a shaped first train of pulses to specifically probe a spectral feature of interest from a sample, and to reduce information from features that are not of interest from the sample. The modulator system is for modulating a property of at least one of the shaped first train of pulses and the second train of pulses at a modulation frequency. The optical detector is for detecting an integrated intensity of substantially all optical frequency components of a train of pulses of interest transmitted or reflected through the common focal volume. The processor is for detecting a modulation at the modulation frequency of the integrated intensity of substantially all of the optical frequency components of the train of pulses of interest due to the non-linear interaction of the shaped first train of pulses with the second train of pulses as modulated in the common focal volume, and for providing an output signal for a pixel of an image for the microscopy imaging system.

    Abstract translation: 公开了一种显微镜成像系统,其包括光源系统,光谱整形器,调制器系统,光学系统,光学检测器和处理器。 光源系统用于提供第一脉冲串和第二脉冲串。 频谱整形器用于频谱修改频率分量的宽带范围的至少一些频率分量的光学特性,使得频率分量的宽带范围成形,产生成形的第一脉冲串,从而特别地探测来自 样本,并从样本中不感兴趣的特征中减少信息。 调制器系统用于以调制频率调制成形的第一脉冲序列和第二脉冲串中的至少一个的性质。 光学检测器用于检测通过公共焦点体积传输或反射的感兴趣的脉冲串的基本上所有的光学频率分量的积分强度。 处理器用于检测由于成形的第一脉冲序列与第二脉冲串的非线性相互作用而导致的感兴趣的脉冲串的基本上所有的光学频率分量的积分强度的调制频率的调制 在公共焦点体积中调制,并且为显微镜成像系统提供用于图像的像素的输出信号。

    Laser Induced Breakdown Spectroscopy (LIBS) Apparatus Based on High Repetition Rate Pulsed Laser
    122.
    发明申请
    Laser Induced Breakdown Spectroscopy (LIBS) Apparatus Based on High Repetition Rate Pulsed Laser 有权
    基于高重复脉冲激光的激光诱导击穿光谱(LIBS)装置

    公开(公告)号:US20160069745A1

    公开(公告)日:2016-03-10

    申请号:US14845980

    申请日:2015-09-04

    CPC classification number: G01J3/443 G01J3/0208 G01J3/06 G01J3/10 G01J3/28

    Abstract: This invention discloses a laser induced breakdown spectroscopy (LIBS) apparatus based on a high repetition rate pulsed laser. The laser produces a train of laser pulses at a high repetition rate in the kHz or even higher range. When the laser beam hits the sample, it generates several thousands of micro-plasmas per second. Synchronized miniature CCD array optical spectrometer modules collect the LIBS signal from these micro-plasmas. By adjusting the integration time of the spectrometer to cover a plurality of periods of the laser pulse train, the spectrometer integrates the LIBS signal produced by this plurality of laser pulses. Hence the intensity of the obtained LIBS spectrum can be greatly improved to increase the signal-to-noise ratio (SNR) and lower the limit of detection (LOD). In addition, the influence of pulse to pulse variation of the laser is minimized since the obtained LIBS spectrum is the spectrum of a plurality of micro-plasmas produced by a plurality of laser pulses. The high repetition rate laser also makes it possible for fast scanning the laser beam over the sample surface such that an average spectrum of the sample is collected to overcome the sample non-uniformity issue or for performing spectral imaging of the sample by correlating the obtained LIBS spectrum with the position of the scanning laser beam.

    Abstract translation: 本发明公开了一种基于高重复脉冲激光的激光诱导击穿光谱(LIBS)装置。 激光器在kHz或甚至更高的范围内以高重复率产生一串激光脉冲。 当激光束撞击样品时,它每秒产生数千个微等离子体。 同步微型CCD阵列光谱仪模块从这些微等离子体收集LIBS信号。 通过调整光谱仪的积分时间来覆盖激光脉冲串的多个周期,光谱仪将由多个激光脉冲产生的LIBS信号进行积分。 因此,可以大大提高所获得的LIBS频谱的强度,以增加信噪比(SNR)并降低检测极限(LOD)。 此外,由于获得的LIBS光谱是由多个激光脉冲产生的多个微等离子体的光谱,所以激光器的脉冲对脉冲变化的影响被最小化。 高重复率激光器还使得可以在样品表面上快速扫描激光束,使得采集样品的平均光谱以克服样品不均匀性问题或通过将获得的LIBS相关来进行样品的光谱成像 光谱与扫描激光束的位置。

    Biological optical measurement instrument and operation method therefor
    124.
    发明授权
    Biological optical measurement instrument and operation method therefor 有权
    生物光学测量仪器及其操作方法

    公开(公告)号:US09259176B2

    公开(公告)日:2016-02-16

    申请号:US13880744

    申请日:2011-11-02

    Inventor: Hiromichi Suzuki

    Abstract: A biological optical measurement instrument includes a single temperature sensor that detects a radiation temperature from a plurality of light emitting elements that emit light of a predetermined wavelength, and an absorption coefficient correcting unit that corrects an absorption coefficient value of a notable substance inside the object on the basis of the radiation temperature detected by the temperature sensor, referring to data indicating a correspondence relationship between a temperature obtained in advance for each emitted light of the plurality of light emitting elements and an absorption coefficient value that varies according to the temperature.

    Abstract translation: 一种生物光学测量仪器,包括从发出预定波长的光的多个发光元件检测辐射温度的单一温度传感器,以及将物体内的显着物质的吸收系数值校正为吸收系数值的吸收系数校正单元, 以温度传感器检测出的辐射温度为基础,参照表示多个发光元件的每个发光的预先获得的温度与根据温度变化的吸收系数值之间的对应关系的数据。

    Spectroscopy systems and methods using quantum cascade laser arrays with lenses
    125.
    发明授权
    Spectroscopy systems and methods using quantum cascade laser arrays with lenses 有权
    使用带透镜的量子级联激光阵列的光谱系统和方法

    公开(公告)号:US09255841B2

    公开(公告)日:2016-02-09

    申请号:US13873636

    申请日:2013-04-30

    Abstract: A spectroscopy system includes an array of quantum cascade lasers (QCLs) that emits an array of non-coincident laser beams. A lens array coupled to the QCL array substantially collimates the laser beams, which propagate along parallel optical axes towards a sample. The beams remain substantially collimated over the lens array's working distance, but may diverge when propagating over longer distances. The collimated, parallel beams may be directed to/through the sample, which may be within a sample cell, flow cell, multipass spectroscopic absorption cell, or other suitable holder. Alternatively, the beams may be focused to a point on, near, or within the target using a telescope or other suitable optical element(s). When focused, however, the beams remain non-coincident; they simply intersect at the focal point. The target transmits, reflects, and/or scatters this incident light to a detector, which transduces the detected radiation into an electrical signal representative of the target's absorption or emission spectrum.

    Abstract translation: 光谱系统包括发射非重合激光束阵列的量子级联激光器阵列(QCL)。 耦合到QCL阵列的透镜阵列基本上准直了沿着平行光轴朝向样本传播的激光束。 光束在透镜阵列的工作距离上保持基本上准直,但是当在较长距离上传播时可能会发散。 准直的平行光束可以被引导到/通过样品,其可以在样品池,流通池,多光谱吸收单元或其它合适的保持器内。 或者,可以使用望远镜或其它合适的光学元件将光束聚焦到靶上,接近或在目标内的点。 然而,当专注时,梁保持不重合; 他们只是在焦点处相交。 目标将该入射光透射,反射和/或散射到检测器,检测器将检测到的辐射转换成代表目标吸收或发射光谱的电信号。

    APPARATUS AND METHODS FOR EXTRACTING TOPOGRAPHIC INFORMATION FROM INSPECTED OBJECTS
    126.
    发明申请
    APPARATUS AND METHODS FOR EXTRACTING TOPOGRAPHIC INFORMATION FROM INSPECTED OBJECTS 有权
    从检查对象提取地形信息的装置和方法

    公开(公告)号:US20160033332A1

    公开(公告)日:2016-02-04

    申请号:US14450627

    申请日:2014-08-04

    Abstract: Systems and methods for extracting topographic information from inspected objects to identify defects in the inspected objects. A part to be inspected is illuminated with at least two different colors emitted from an illuminator providing a gradient of light consisting of the at least two different colors. A single color image of the illuminated part to be inspected is acquired, providing a color-coded topographic mapping of the part to be inspected due, at least in part, to the gradient of light. Topographic monochrome views of the part to be inspected may be generated from the single color image. Each view of the topographic monochrome views may enhance a different type of feature or defect present in the part to be inspected which can be analyzed and detected.

    Abstract translation: 用于从检查对象中提取地形信息以识别被检查对象中的缺陷的系统和方法。 要被检查的部件被照射到从照明器发射的至少两种不同的颜色,提供由至少两种不同颜色组成的光的梯度。 获取要被检查的被照明部分的单色图像,至少部分地提供待检查部分的颜色编码的地形图。 要检查的零件的地形单色视图可以从单色图像生成。 地形单色视图的每个视图可以增强可被分析和检测的待检查部分中存在的不同类型的特征或缺陷。

    DISCOVERING AND CONSTRAINING IDLE PROCESSES
    128.
    发明申请
    DISCOVERING AND CONSTRAINING IDLE PROCESSES 审中-公开
    发现和限制空闲过程

    公开(公告)号:US20160025561A1

    公开(公告)日:2016-01-28

    申请号:US14807286

    申请日:2015-07-23

    Inventor: Yue Tian Ting Wang

    CPC classification number: G01J3/10 G01J3/12 G01J3/28 G01J3/42

    Abstract: A spectroscopy system and method includes illuminating a target with a wideband light pulse that includes an entire testing wavelength spectrum. The light pulse is transformed with a dispersive medium to introduce a frequency-based time delay to the light pulse after the light pulse has interacted with a target. The dispersed light pulse is converted to a time-domain electrical signal with a photodiode. The time-domain electrical signal is converted into a spectral profile of the target.

    Abstract translation: 光谱系统和方法包括用包括整个测试波长光谱的宽带光脉冲照射目标。 用分散介质转换光脉冲,以在光脉冲与目标相互作用之后,将光脉冲引入基于频率的时间延迟。 分散的光脉冲被转换成具有光电二极管的时域电信号。 时域电信号被转换成目标的光谱分布。

    Color Measuring Apparatus
    129.
    发明申请
    Color Measuring Apparatus 审中-公开
    色彩测量仪器

    公开(公告)号:US20160011052A1

    公开(公告)日:2016-01-14

    申请号:US14798920

    申请日:2015-07-14

    Inventor: Beat Frick

    Abstract: A color measuring apparatus includes a measurement assembly which includes at least one illumination assembly for applying substantially parallel illumination light to a measurement spot of a measurement object and a pick-up assembly for capturing the measurement light radiated back from the measurement spot in an observation direction and for converting the same into corresponding electrical signals. The illumination assembly includes at least two illumination subassemblies which illuminate the measurement spot from different illumination sub-directions near a first preset nominal illumination direction, each with preferably parallel illumination light. By the illumination from different illumination sub-directions slightly deviating from the nominal illumination direction, angular errors of the illumination assembly can be compensated for in a simple manner.

    Abstract translation: 一种颜色测量装置,包括:测量组件,其包括至少一个照明组件,用于将大致平行的照明光施加到测量对象的测量点;以及拾取组件,用于捕获从观测方向上的测量点反射的测量光 并将其转换成相应的电信号。 照明组件包括至少两个照明子组件,其照射来自第一预设标称照明方向附近的不同照明子方向的测量点,每个具有优选平行的照明光。 通过稍微偏离标称照明方向的不同照明子方向的照明,可以以简单的方式补偿照明组件的角度误差。

    Portable spectrometer
    130.
    发明授权
    Portable spectrometer 有权
    便携式光谱仪

    公开(公告)号:US09234839B2

    公开(公告)日:2016-01-12

    申请号:US14079280

    申请日:2013-11-13

    Abstract: A portable spectrometer device includes an illumination source for directing at a sample, and a tapered light pipe (TLP) for capturing light interacting with the sample at a first focal ratio and for delivering the light at a second focal ratio lower than the first focal ratio. A linearly variable filter (LVF) separates the captured light into a spectrum of constituent wavelength signals; and a detector array, including a plurality of pixels, each of the plurality of pixels disposed to receive at least a portion of a plurality of the constituent wavelength signals provides a power reading for each constituent wavelength. Preferably, the TLP is lensed at one end, and recessed in a protective boot with stepped inner walls. The gap between the TLP and LVF is minimized to further enhance resolution and robustness.

    Abstract translation: 便携式光谱仪装置包括用于引导样品的照明源和用于以第一焦距比捕获与样品相互作用的光的锥形光管(TLP),并且以比第一焦距比低的第二焦距传送光 。 线性可变滤波器(LVF)将捕获的光分离成波长信号的频谱; 以及包括多个像素的检测器阵列,所述多个像素中的每一个被设置为接收多个所述组成波长信号的至少一部分,为每个构成波长提供功率读数。 优选地,TLP在一端镜片,并且凹陷在具有阶梯状内壁的保护靴中。 TLP和LVF之间的差距被最小化以进一步提高分辨率和鲁棒性。

Patent Agency Ranking