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    High-speed, rugged, time-resolved, Raman spectrometer for sensing multiple components of a sample and for diagnostics of pathological skin conditions such as cancer
    21.
    发明授权
    High-speed, rugged, time-resolved, Raman spectrometer for sensing multiple components of a sample and for diagnostics of pathological skin conditions such as cancer 有权
    高速，坚固，时间分辨的拉曼光谱仪，用于感测样品的多个组分，并诊断病理性皮肤病症如癌症

    公开(公告)号：US07944555B2

    公开(公告)日：2011-05-17

    申请号：US12551404

    申请日：2009-08-31

    Applicant: Ricardo Claps

    Inventor： Ricardo Claps

    IPC: G01J3/44

    CPC classification number: G01J3/44 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/1895 ,  G01J3/26 ,  G01J3/2889 ,  G01J3/32 ,  G01J2003/123 ,  G01N21/65

    Abstract: A new architecture for implementing a time-resolved Raman spectrometer is 2-3 orders of magnitude faster than current systems. In one embodiment, the invention employs a rotating optical switch to time multiplex an input signal through multiple band-pass filters and into a single optical detector which is electrically activated only when the filtered input light pulse is about to impact it.Time-multiplexing the input signal through multiple optical filters and time-sequencing the optical detector enables the device to detect and analyze 2-3 orders of magnitude faster than current designs. In one embodiment, the system may be employed for the diagnostics of a pathological condition of skin tissue in patients, such as malignant melanoma or other types of skin cancers and abnormal conditions.

    Abstract translation: 实现时间分辨拉曼光谱仪的新架构比现有系统快2-3个数量级。 在一个实施例中，本发明采用旋转光开关，通过多个带通滤波器对输入信号进行时间复用，并将其转换成仅在滤波后的输入光脉冲即将影响时才被电激活的单个光检测器。 通过多个光学滤波器对输入信号进行时分复用，并对光学检测器进行时间排序，使器件能够比目前的设计更快地检测和分析2-3个数量级。 在一个实施方案中，该系统可用于诊断患者皮肤组织的病理状况，例如恶性黑素瘤或其他类型的皮肤癌症和异常状况。

    Spectral instrument
    22.
    发明授权
    Spectral instrument 失效
    光谱仪

    公开(公告)号：US07466419B2

    公开(公告)日：2008-12-16

    申请号：US10547128

    申请日：2004-02-26

    Applicant: Kazunori Yamauchi ,  Hiroyuki Sugiyama

    Inventor： Kazunori Yamauchi ,  Hiroyuki Sugiyama

    IPC: G01J3/51

    CPC classification number: G01N21/31 ,  G01J3/021 ,  G01J3/36 ,  G01J3/51 ,  G01J2003/1221 ,  G01J2003/1226 ,  G01J2003/123 ,  G01J2003/1239 ,  G01N21/255 ,  G01N21/892 ,  G01N21/896 ,  G01N21/90 ,  G01N2021/3137 ,  G01N2021/3166 ,  G01N2021/3177

    Abstract: In this spectral instrument, a plurality of interference filters 31, 32 . . . with transmitting wavebands different from each other are arranged in order so that light reflected by a specific interference filter 31 is made incident on the interference filter 32 on the next stage, and at positions on which light transmitted through each interference filter is made incident, photodetecting devices 41, 42 . . . are provided, wherein a silver thin film 31a with a thickness of 20 to 200 nm is provided on the light incidence surface side of the interference filter 31 on the first stage.

    Abstract translation: 在该光谱仪器中，多个干涉滤光器31,32。 。 。 相互不同的发送波段按顺序排列，使得由特定干涉滤光器31反射的光入射到下一级的干涉滤光器32上，并且在透过每个干涉滤光器的光入射的位置处受光检测 装置41,42。 。 。 ，其中在第一级上的干涉滤光器31的光入射面侧设置有厚度为20〜200nm的银薄膜31a。

    OPTICAL MEASUREMENT APPARATUS
    23.
    发明申请
    OPTICAL MEASUREMENT APPARATUS 审中-公开
    光学测量装置

    公开(公告)号：US20080117421A1

    公开(公告)日：2008-05-22

    申请号：US12014429

    申请日：2008-01-15

    Applicant: Mitsushiro YAMAGUCHI ,  Mitsuo HARADA

    Inventor： Mitsushiro YAMAGUCHI ,  Mitsuo HARADA

    IPC: G01N21/76 ,  G01N21/64

    CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0235 ,  G01J3/0289 ,  G01J3/06 ,  G01J3/08 ,  G01J3/10 ,  G01J3/42 ,  G01J2003/123 ,  G01N21/6428 ,  G01N21/6445

    Abstract: An optical measurement apparatus which includes at least one each of a light source, an optical element, a photodetector, and a sample container, and which measures a physical property of a biological sample in a solution retained by the sample container according to a plurality of kinds of measurement items, wherein a combination of the light source, the optical element, and the photodetector is selected or changed according to the measurement item, and a position where the photodetector is located is adjusted according to the selection or change based on intensity of light accepted by the photodetector.

    Abstract translation: 一种光学测量装置，其包括光源，光学元件，光电检测器和样品容器中的至少一个，并且根据多个测量装置测量由样品容器保留的溶液中的生物样品的物理性质 根据测量项目选择或改变光源，光学元件和光电检测器的组合的测量项目的种类，并且根据根据测量项目的强度来选择或改变光电探测器所在的位置 由光电检测器接受的光。

    REFRACTIVE-DIFFRACTIVE SPECTROMETER
    24.
    发明申请
    REFRACTIVE-DIFFRACTIVE SPECTROMETER 失效
    折射衍射光谱仪

    公开(公告)号：US20030231308A1

    公开(公告)日：2003-12-18

    申请号：US09991038

    申请日：2001-11-21

    Inventor： Edward M. Granger

    IPC: G01J003/28

    CPC classification number: G02B6/29311 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/12 ,  G01J3/28 ,  G01J2003/123 ,  G02B6/29373

    Abstract: A diffraction grating and a prism with the appropriate characteristics are employed to provide a combined dispersive characteristic that is substantially linear over the visible spectrum. Radiation from the grating and prism is collimated by a lens towards a detector array. The grating or a telecentric stop between the grating and prism is placed at a focal point of the lens in a telecentric arrangement so that equal magnification is achieved at the detector array. If the detector array is replaced by a plurality of optical channels, a multiplexer/demultiplexer is obtained.

    Abstract translation: 使用衍射光栅和具有适当特性的棱镜来提供在可见光谱上基本上线性的组合色散特性。 来自光栅和棱镜的辐射由透镜朝向检测器阵列准直。 光栅或光栅和棱镜之间的远心光阑以远心布置放置在透镜的焦点处，使得在检测器阵列处实现相等的放大倍率。 如果检测器阵列被多个光通道替代，则获得多路复用器/解复用器。

    Rectangular impinging beam
    26.
    发明授权
    Rectangular impinging beam 失效
    矩形冲击梁

    公开(公告)号：US4737034A

    公开(公告)日：1988-04-12

    申请号：US236543

    申请日：1981-02-20

    Applicant: Donald R. Webster

    Inventor： Donald R. Webster

    IPC: G01J3/12 ,  G01J3/51

    CPC classification number: G01J3/12 ,  G01J2003/123 ,  G01J3/0235

    Abstract: An optical analysis system employs a rectangular beam of light passing through interference filters to analyze the constituents of a test sample moving through the beam. A plurality of interference filters are moved successively through the beam between the source of the beam and the sample and are tilted about an axis as they are moved, thereby transmitting a range of wavelengths to the sample. Skew rays of light in the beam strike the filters at different angles from the angles at which rays parallel to the axis of the beam strike the filters and so transmit wavelengths different from those of rays parallel to the axis of the beam. The angle deviation is greatest for the skew light rays which are skewed from the axis of the beam in a plane perpendicular to the tilt axis of the filters. Thus, the shorter dimension of the rectangular beam is arranged to be perpendicular to the tilt axis of the filters.

    Abstract translation: 光学分析系统采用通过干涉滤光片的矩形光束来分析通过光束移动的测试样品的成分。 多个干涉滤光片依次通过光源和样品之间的光束移动，并且在它们被移动时围绕轴倾斜，从而向样品传输一定范围的波长。 光束中的偏斜光束从与平行于光束的光线的射线撞击过滤器的角度不同的角度以不同的角度撞击过滤器，因此传输与平行于光束轴线的光线不同的波长。 对于在垂直于滤光片的倾斜轴的平面中从光束的轴线偏斜的偏斜光线，角度偏差最大。 因此，矩形梁的较短尺寸被布置成垂直于过滤器的倾斜轴线。

    Portable reflectance spectrometer
    27.
    发明授权
    Portable reflectance spectrometer 失效
    便携式反射光谱仪

    公开(公告)号：US4043668A

    公开(公告)日：1977-08-23

    申请号：US561369

    申请日：1975-03-24

    Applicant: Alexander F. H. Goetz ,  Richard A. Graham ,  Tetsuo Ozawa

    Inventor： Alexander F. H. Goetz ,  Richard A. Graham ,  Tetsuo Ozawa

    IPC: G01J3/00 ,  G01J3/12 ,  G01J3/32 ,  G01N21/31 ,  G01J3/48

    CPC classification number: G01J3/32 ,  G01J2003/1217 ,  G01J2003/123 ,  G01J3/0232 ,  G01J3/0272 ,  G01J3/0286 ,  G01J3/0291 ,  G01N2021/3174

    Abstract: A portable reflectance spectrometer is disclosed. The spectrometer essentially includes an optical unit and an electronic recording unit. The optical unit includes a pair of thermoelectrically-cooled detectors, for detecting total radiance and selected radiance projected through a circular variable filter wheel, and is capable of operating to provide spectral data in the range 0.4 .mu.m to 2.5 .mu.m without requiring conventional substitution of filter elements. The electronic recording unit essentially includes power supplies, amplifiers, and digital recording electronics designed to permit recordation of data on tape casettes. Both the optical unit and electronic recording unit are packaged to permit carriage as backpack items and thereby be manually portable.

    Abstract translation: 公开了便携式反射光谱仪。 光谱仪基本上包括光学单元和电子记录单元。 光学单元包括一对热电冷却检测器，用于检测通过圆形可变滤光轮投射的总辐射度和选定辐射，并且能够操作以提供0.4μm至2.5μm范围内的光谱数据，而不需要常规替代 的过滤元件。 电子记录单元基本上包括设计用于允许在磁带盒上记录数据的电源，放大器和数字记录电子设备。 光学单元和电子记录单元都被包装以允许作为背包物品运输，从而可手动地携带。

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