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公开(公告)号：AU8374491A
公开(公告)日：1992-03-12
申请号：AU8374491
申请日：1991-09-09
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , KESTER JEFFREY A , HOLLEMAN WILLIAM H , DE BISWANATH , ZYDOWSKY THOMAS M , KERKMAN DANIEL J , DEBERNARDIS JOHN F , ROSENBERG SAUL H , SHIOSAKI KAZUMI , BASHA FATIMA Z , TASKER ANDREW S , GELDERN THOMAS W VON
IPC: A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4427 , A61K31/443 , A61K31/495 , A61K31/50 , A61K31/505 , A61K31/53 , A61P1/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/02 , A61P15/00 , A61P27/02 , A61P43/00 , C07D213/64 , C07D213/70 , C07D213/71 , C07D213/72 , C07D213/74 , C07D213/80 , C07D239/26 , C07D239/34 , C07D239/42 , C07D257/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , A61K31/43 , A61K31/535 , A61K31/41
Abstract: Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis or to treat gastrointestinal disorders associated with enhanced contractility and/or motility of intestinal smooth muscle or to treat contractile disorders of the uterus.
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公开(公告)号：BRPI0820043A2
公开(公告)日：2015-05-12
申请号：BRPI0820043
申请日：2008-11-20
Applicant: ABBOTT LAB
Inventor： GELDERN THOMAS W VON , BARKALOW JUFANG H , BARNES DAVID M , HAIGHT ANTHONY R , HENGEVELD JOHN E , LI XIAOFENG , MCLAUGHLIN MAUREEN A , NOONAN WILLIAM T , PEI ZHONGHUA , WU-WONG JINSHYUN RUTH
IPC: C07C401/00
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公开(公告)号：AU2005201160B2
公开(公告)日：2007-12-13
申请号：AU2005201160
申请日：2005-03-17
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , JAE HWAN-SOO , TASKER ANDREW S , LIU GANG , KING STEVEN A , GELDERN THOMAS W VON , HENRY KENNETH J , HUTCHINS CHARLES W , BOYD STEVEN A , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , WITTENBERGER STEVEN J
IPC: C07D405/00
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公开(公告)号：UY27862A1
公开(公告)日：2004-04-30
申请号：UY27862
申请日：2003-06-20
Applicant: ABBOTT LAB
Inventor： KYM PHILIP R , JACOBSON PEER B , LINK JAMES T , LAI CHUNQIU , BISHOP RICHARD D , TU NOAH , RICHARDS STEVEN J , GATES BRADLEY D , GELDERN THOMAS W VON
IPC: A61K31/575 , A61K31/661 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/46 , A61P9/12 , A61P43/00 , C07J9/00 , C07J41/00 , C07J51/00 , A61P7/12 , A61P5/44
Abstract: Nuevos compuestos que son antagonistas selectivos del receptor de glucocorticoides en el hígado, métodos para preparar dichos compuestos, y métodos para usar tales compuestos en la regulación del metabolismo, especialmente para bajar los niveles de glucosa sérica, los niveles de insulina o los niveles de lípidos, y/o reducir el peso corporal.
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公开(公告)号：TR200101233T2
公开(公告)日：2002-06-21
申请号：TR200101233
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , GELDERN THOMAS W VON , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY KENNETH J , LIU GANY , WITTENBERGER STEVEN J , KING STEVEN A
IPC: C07D491/048 , A61K31/40 , A61K31/41 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/495 , A61K31/506 , A61K31/535 , A61K31/55 , A61P1/00 , A61P1/04 , A61P7/02 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/08 , A61P13/12 , A61P21/00 , A61P21/04 , A61P25/06 , A61P35/00 , A61P43/00 , C07D207/16 , C07D207/26 , C07D207/27 , C07D403/04 , C07D405/00 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D491/056
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Patent Agency Ranking
公开(公告)号：AU2763602A
公开(公告)日：2002-05-16
申请号：AU2763602
申请日：2002-03-25
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , KING STEVEN A , WITTENBERGER STEVEN J , LIU GANG , HENRY KENNETH J , SZCZEPANKIEWICZ BRUCE G , SORENSEN BRYAN K , KESTER JEFFREY A , GELDERN THOMAS W VON , TASKER ANDREW S , JAE HWAN-SOO , HUTCHINS CHARLES W , BOYD STEVEN A
IPC: C07D405/00
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公开(公告)号：BR0009426A
公开(公告)日：2002-04-09
申请号：BR0009426
申请日：2000-04-03
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A , GELDERN THOMAS W VON , WANG SHELDON
IPC: C07D243/08 , A61K20060101 , A61K31/10 , A61K31/165 , A61K31/33 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/472 , A61K31/496 , A61K31/4965 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61K31/55 , A61K31/551 , A61P20060101 , A61P29/00 , A61P37/06 , C07C20060101 , C07C323/60 , C07C323/62 , C07D20060101 , C07D205/04 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/26 , C07D207/27 , C07D207/273 , C07D209/08 , C07D209/12 , C07D211/20 , C07D211/22 , C07D211/46 , C07D211/60 , C07D211/62 , C07D211/64 , C07D211/66 , C07D211/70 , C07D213/40 , C07D213/74 , C07D213/81 , C07D215/24 , C07D217/02 , C07D217/04 , C07D217/06 , C07D233/61 , C07D239/42 , C07D241/04 , C07D241/24 , C07D257/04 , C07D279/12 , C07D295/18 , C07D295/185 , C07D295/20 , C07D295/205 , C07D295/22 , C07D295/26 , C07D307/24 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/66 , C07D319/18 , C07D401/04 , C07D401/12 , C07D405/12 , C07D417/12 , C07D471/20 , C07D487/04 , C07D491/113 , C07D521/00
Abstract: The present invention relates to cinnamide compounds of formula (I), in which at least one of R1 to R5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims, that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal.
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公开(公告)号：BR9815296A
公开(公告)日：2001-11-20
申请号：BR9815296
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , GELDERN THOMAS W VON , KESTER JEFFREY A , SORENSEN RYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY KENNETH J , LIU GANG , WITTENBERGER STEVEN J , KING STEVEN A
IPC: C07D491/048 , A61K31/40 , A61K31/41 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/495 , A61K31/506 , A61K31/535 , A61K31/55 , A61P1/00 , A61P1/04 , A61P7/02 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/08 , A61P13/12 , A61P21/00 , A61P21/04 , A61P25/06 , A61P35/00 , A61P43/00 , C07D207/16 , C07D207/26 , C07D207/27 , C07D403/04 , C07D405/00 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D491/056
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公开(公告)号：IS6097A
公开(公告)日：2001-09-28
申请号：IS6097
申请日：2001-09-28
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , GELDERN THOMAS W VON , WINN MARTIN , XIN ZHILI , WANG SHELDON , BOYD STEVEN A , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A , JAE HWAN-SOO , LYNCH JOHN K
IPC: C07D243/08 , A61K20060101 , A61K31/10 , A61K31/165 , A61K31/33 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/472 , A61K31/496 , A61K31/4965 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61K31/55 , A61K31/551 , A61P20060101 , A61P29/00 , A61P37/06 , C07C20060101 , C07C323/60 , C07C323/62 , C07D20060101 , C07D205/04 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/26 , C07D207/27 , C07D207/273 , C07D209/08 , C07D209/12 , C07D211/20 , C07D211/22 , C07D211/46 , C07D211/60 , C07D211/62 , C07D211/64 , C07D211/66 , C07D211/70 , C07D213/40 , C07D213/74 , C07D213/81 , C07D215/24 , C07D217/02 , C07D217/04 , C07D217/06 , C07D233/61 , C07D239/42 , C07D241/04 , C07D241/24 , C07D257/04 , C07D279/12 , C07D295/18 , C07D295/185 , C07D295/20 , C07D295/205 , C07D295/22 , C07D295/26 , C07D307/24 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/66 , C07D319/18 , C07D401/04 , C07D401/12 , C07D405/12 , C07D417/12 , C07D471/20 , C07D487/04 , C07D491/113 , C07D521/00
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公开(公告)号：ZA9806908B
公开(公告)日：1999-04-26
申请号：ZA9806908
申请日：1998-07-31
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , GELDERN THOMAS W VON , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY KENNETH J , LIU GANG , WITTENBERGER STEVEN J , KING STEVEN A
IPC: A61K20060101 , C07D20060101 , C07F20060101 , C07D , A61K , C07F
CPC classification number: Y02P20/55
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