Patent search ap:("ABBOTT LAB") AND inv:"KOLACZKOWSKI LAWRENCE" Page 3

21.

发明专利
2-((R)-2-Methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide Crystalline Form 1 未知

公开(公告)号：AU2008310781A1

公开(公告)日：2009-04-16

申请号：AU2008310781

申请日：2008-10-10

Applicant: ABBOTT LAB

Inventor： KOLACZKOWSKI LAWRENCE

IPC: C07D487/04 , A61K31/4184 , A61P35/00

22.

发明专利
Retroviral protease inhibiting compounds 未知

公开(公告)号：AU2007231810A1

公开(公告)日：2007-11-29

申请号：AU2007231810

申请日：2007-11-01

Applicant: ABBOTT LAB

Inventor： PLATA DANIEL J , TIEN JIEH-HEH J , COOPER ARTHUR J , KEMPF DALE J , PATEL KETAN M , CHEN XIAOQI , DICKMAN DANIEL A , STONER ERIC J , KOLACZKOWSKI LAWRENCE , CONDON STEPHEN L , BETEBENNER DAVID A , OLIVER PATRICIA A , KUMAR GONDI N , STENGEL PETER J , HANNICK STEVEN M , HERRIN THOMAS R , NORBECK DANIEL W , SHAM HING LEUNG , LIU JIH-HUA

IPC: C07D239/10 , A61K31/415 , C07D207/26 , C07D207/40 , C07D233/32 , C07D239/22 , C07D241/08 , C07D263/22

23.

发明专利
Octahydro-pyrrolo[3,4-b] pyrrole derivatives and their use as histamine-3 receptor ligands 未知

公开(公告)号：AU2007220889A1

公开(公告)日：2007-09-07

申请号：AU2007220889

申请日：2007-02-16

Applicant: ABBOTT LAB

Inventor： FICKES MICHAEL G , SUN MINGHUA , ZHAO CHEN , SHEIKH AHMAD Y , HENRY RODGER F , BARNES DAVID M , GREGG ROBERT J , HAIGHT ANTHONY R , KOLACZKOWSKI LAWRENCE , WITTENBERGER STEVEN J , ZHANG GEOFF G Z , COWART MARLON D , LOU XIAOCHUN , ZHENG GUO ZHU , BLACK LAWRENCE A , CHANG SOU-JEN

IPC: C07D487/04 , A61K31/407

Abstract: Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.

24.

发明专利
Slouceniny inhibující proteázy retroviru 未知

公开(公告)号：CZ296915B6

公开(公告)日：2006-07-12

申请号：CZ2004762

申请日：1996-12-06

Applicant: ABBOTT LAB

Inventor： SHAM HING LEUNG , NORBECK DANIEL W , CHEN XIAOQI , BETEBENNER DAVID A , KEMPF DALE J , HERRIN THOMAS R , KUMAR GONDI N , CONDON STEPHEN L , COOPER ARTHUR J , DICKMAN DANIEL A , HANNICK STEVEN M , KOLACZKOWSKI LAWRENCE , OLIVER PATRICIA A , PLATA DANIEL J , STENGEL PETER J , STONER ERIC J , TIEN JIEH-HEH J , LIU JIH-HUA , PATEL KETAN M

IPC: C07D239/10 , C07D253/00 , A61K31/00 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/415 , A61K31/4164 , A61K31/4166 , A61K31/4184 , A61K31/42 , A61K31/421 , A61K31/425 , A61K31/427 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61K31/47 , A61K31/495 , A61K31/496 , A61K31/4965 , A61K31/505 , A61K31/513 , A61K31/53 , A61K31/55 , A61K38/05 , A61K45/00 , A61P31/00 , A61P31/18 , A61P31/22 , A61P43/00 , C07C231/12 , C07C235/20 , C07C273/18 , C07C275/16 , C07D20060101 , C07D207/22 , C07D207/26 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/40 , C07D207/404 , C07D207/408 , C07D207/416 , C07D211/72 , C07D211/84 , C07D223/06 , C07D233/28 , C07D233/30 , C07D233/32 , C07D233/36 , C07D233/40 , C07D233/42 , C07D233/66 , C07D239/06 , C07D239/20 , C07D239/22 , C07D241/06 , C07D241/08 , C07D241/18 , C07D243/04 , C07D253/06 , C07D263/16 , C07D263/20 , C07D263/22 , C07D263/34 , C07D265/04 , C07D267/04 , C07D277/12 , C07D277/32 , C07D277/34 , C07D279/06 , C07D281/02 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12

Abstract: Slouceniny obecného vzorce III a IV, které jsou meziprodukty pro prípravu inhibitoru retrovirových proteáz.

25.

发明专利
具有抗血管生成和抗癌症活性的磺胺藥物未知

公开(公告)号：HK1080065A1

公开(公告)日：2006-04-21

申请号：HK05112203

申请日：2005-12-30

Applicant: ABBOTT LAB

Inventor： COMESS KENNETH M , ERICKSON SCOTT A , HENKIN JACK , KALVIN DOUGLAS M , KAWAI MEGUMI , KIM KI H , BAMAUNG NWE Y , PARK CHAN HOON , SHEPPARD GEORGE S , VASUDEVAN ANIL , WANG JIEYI , BARNES DAVID M , FIDANZE STEVE D , KOLACZKOWSKI LAWRENCE , MANTEI ROBERT A , PARK DAVID C , SANDERS WILLIAM J , TEDROW JASON S , WANG GARY T

IPC: C07C20060101 , A61P35/00 , C07C311/08 , C07C311/13 , C07C311/21 , C07C311/29 , C07C311/37 , C07C311/44 , C07C311/46 , C07C317/28 , C07C323/25 , C07C323/49 , C07C323/63 , C07C323/67 , C07D209/08 , C07D209/42 , C07D213/70 , C07D213/71 , C07D215/36 , C07D215/48 , C07D231/18 , C07D233/54 , C07D233/84 , C07D261/10 , C07D285/06 , C07D285/14 , C07D333/34 , C07D333/38 , C07D413/04

26.

发明专利
RETROVIRAL PROTEASE INHIBITING COMPOUNDS 未知

公开(公告)号：CA2285119C

公开(公告)日：2005-09-20

申请号：CA2285119

申请日：1996-12-06

Applicant: ABBOTT LAB

Inventor： HERRIN THOMAS R , BETEBENNER DAVID A , KEMPF DALE J , KOLACZKOWSKI LAWRENCE , OLIVER PATRICIA A , CHEN XIAOQI , PLATA DANIEL J , NORBECK DANIEL W , COOPER ARTHUR J , DICKMAN DANIEL A , SHAM HING LEUNG , STENGEL PETER J , HANNICK STEVEN M , CONDON STEPHEN L , STONER ERIC J , TIEN JIEH-HEH J , LIU JIH-HUA , KUMAR GONDI N , PATEL KETAN M

IPC: C07D253/00 , A61K31/00 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/415 , A61K31/4164 , A61K31/4166 , A61K31/4184 , A61K31/42 , A61K31/421 , A61K31/425 , A61K31/427 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61K31/47 , A61K31/495 , A61K31/496 , A61K31/4965 , A61K31/505 , A61K31/513 , A61K31/53 , A61K31/55 , A61K38/05 , A61K45/00 , A61P31/18 , A61P43/00 , C07C231/12 , C07C235/20 , C07C273/18 , C07C275/16 , C07D20060101 , C07D207/22 , C07D207/26 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/40 , C07D207/404 , C07D207/408 , C07D207/416 , C07D211/72 , C07D211/84 , C07D223/06 , C07D233/28 , C07D233/30 , C07D233/32 , C07D233/36 , C07D233/40 , C07D233/42 , C07D233/66 , C07D239/06 , C07D239/10 , C07D239/20 , C07D239/22 , C07D241/06 , C07D241/08 , C07D241/18 , C07D243/04 , C07D253/06 , C07D263/16 , C07D263/20 , C07D263/22 , C07D263/34 , C07D265/04 , C07D267/04 , C07D277/12 , C07D277/32 , C07D277/34 , C07D279/06 , C07D281/02 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12

Abstract: A compound of formula (I) is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclose d. (see formula I)

27.

发明专利
PIRIDINAS SUSTITUIDAS CON ACTIVIDAD ANTI-ANGIOGENICA 未知

公开(公告)号：AR039258A1

公开(公告)日：2005-02-16

申请号：ARP030101186

申请日：2003-04-04

Applicant: ABBOTT LAB

Inventor： HAVIV FORTUNA , BRADLEY MICHAEL , HENKIN JACK , SAUER DARYL , DINGES JURGEN , KOLACZKOWSKI LAWRENCE , PARK DAVID , VASUDEVAN ANIL

IPC: C07D213/82 , A61K31/455 , A61K31/496 , A61K31/497 , A61K31/506 , A61K31/551 , A61P35/00 , C07D401/06 , C07D401/14 , C07D409/14 , C07D413/04 , C07D417/06 , C07D491/10

Abstract: Reivindicación 1: Un compuesto caracterizado porque responde a la fórmula (1) o una sal aceptable para uso farmacéutico del mismo, donde A es un anillo aromático de seis miembros que contiene entre uno y tres átomos de N donde los átomos restantes son de carbono; R1 y R2, junto con el átomo de N al cual están unidos, forman un anillo de cinco a ocho miembros que contiene entre 0 y 2 heteroátomos adicionales seleccionados del grupo formado por N, O y S; donde el anillo puede ser opcionalmente sustituido con uno, dos, o tres sustituyentes seleccionados en forma independiente entre el grupo formado por alcoxialquilo, alcoxicarbonilo, alquilo, alquilcarbonilo, amino, aminocarbonilo, arilo, arilalcoxicarbonilo, arilalquilo, carboxi, formilo, haloalquilo, heterociclo, (heterociclo)alquilo, hidroxi, hidroxialcoxialquilo, hidroxialquilo, y espiroheterociclo; R3 es cada caso se selecciona en forma independiente entre el grupo formado por alquenilo, alcoxi, alcoxialquilo, alcoxicarbonilo, alquilo, alquilcarbonilo, alquilsulfanilo, amino, aminocarbonilo, arilo, arilalquilo, ariloxi, ciano, cianoalquilo, cicloalquilo, (cicloalquil)alquilo; halo, haloalquilo, heterociclo, hidroxi, hidroxialquilo y nitro; X se selecciona del grupo formado por O, S, y CH2; y m es 0-4.