公开(公告)号：DE3144138A1

公开(公告)日：1983-05-19

申请号：DE3144138

申请日：1981-11-06

Applicant: BASF AG

Inventor： KROPP RUDOLF ,  THYES MARCO DR ,  SCHLECKER RAINER DR ,  FRANKE ALBRECHT DR ,  REICHENEDER FRANZ DR ,  AMANN AUGUST DR MED ,  TESCHENDORF HANS-JUERGEN DR ME ,  KRETZSCHMAR ROLF PROF DR MED ,  TRAUT MARTIN DR ,  GRIES JOSEF DR MED

IPC: A61K31/50 ,  A61P9/02 ,  A61P25/00 ,  A61P25/24 ,  A61P25/26 ,  C07D237/20 ,  C07D237/22

公开(公告)号：DE3782954D1

公开(公告)日：1993-01-21

申请号：DE3782954

申请日：1987-01-21

Applicant: BASF AG

Inventor： JANSSEN BERND DR ,  KARBACH STEFAN DR ,  RECKER HANS-GERT DR ,  THYES MARCO DR

IPC: C07C47/238 ,  C07C45/00 ,  C07C45/51 ,  C07C47/21 ,  C07C47/22 ,  C07C47/228 ,  C07C47/232 ,  C07C47/24 ,  C07C47/277 ,  C07C67/00 ,  C07D301/12 ,  C07D303/14 ,  C07D303/16 ,  C07D303/32

Abstract: (A) alpha,beta-substd. acroleins of formula (I) are new where A, B = 1-4C alkyl, naphthyl, biphenyl, or phenyl opt. substd. by one or more halogen, nitro, 1-4C alkyl, 1-4C alkoxy, 1-4C haloalkyl, phenoxy or phenylsulphonyl residues. (B) Also new is the use of cpds. of formula (I) for the prodn. of hydroxymethyl-oxiranes of formula (II). Pref. acroleins (I) are those in which A and B are methyl, tert-butyl phentl, 4-chlorophenyl, 2-fluorophenyl, 3-fluorophenyl, 4-fluorophenyl, 2-fluoro-6-chlorophenyl, 4-bromophenyl, 2,4-dichlorophenyl or 4-tert-butyl-phenyl.

公开(公告)号：DE3735207A1

公开(公告)日：1989-04-27

申请号：DE3735207

申请日：1987-10-17

Applicant: BASF AG

Inventor： EULER KLAUS DR ,  LECHTKEN PETER DR ,  KOHLER WALTER DR ,  HOPPE PETER PAUL DR MED ,  SCHOENER FRANZ-JOSEF DR ,  GEISS KARL-HEINZ DR ,  THYES MARCO DR

IPC: A23K20/137

Abstract: Compositions for promoting growth, reducing fat, and improving the assimilation of fodder and protein content in animals, contain at least one phenylpyridazinone derivative or one of its biocompatible salts.

公开(公告)号：DE3719622A1

公开(公告)日：1988-12-29

申请号：DE3719622

申请日：1987-06-12

Applicant: BASF AG

Inventor： KNAUS GUENTER H DR ,  ERNST HANSGEORG DR ,  THYES MARCO DR ,  PAUST JOACHIM DR

IPC: C07C69/65 ,  C07C69/653 ,  C07F9/40

Abstract: Alkyl gamma -halotiglates of the general formula I (I) where X is Cl or Br and R2 is alkyl of 1 to 3 carbon atoms, having a high E isomer content, are prepared by a process in which (a) the corresponding 2-methyl-but-3-enoate of the general formula II (II) is reacted with chlorine or bromine in the absence of a solvent and (b) the resulting 2-methyl-3,4-dihalobutyrate of the general formula III (III) is dehydrohalogenated by reaction with a solution of an alkali metal hydroxide in an alcohol R2OH, where R2 has the stated meaning, or in a mixture of water and an alcohol R2OH, and the products are further processed to give O,O-dialkyl- gamma -phosphonotiglates of the general formula IV (IV) where R1 is alkyl of 1 to 4 carbon atoms and R2 is alkyl of 1 to 3 carbon atoms, preferably ethyl, by reaction with a trialkyl phosphite and thermal isomerization. The process gives C5 building blocks which are extremely interesting for polyene chemistry, the said building blocks being obtained in good yields and essentially in the form of the required E isomers.

公开(公告)号：AT34741T

公开(公告)日：1988-06-15

申请号：AT84100381

申请日：1984-01-16

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST PROF DR ,  LEHMANN HANS DIETER PROF DR ,  GRIES JOSEF DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER PROF DR

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00

公开(公告)号：CS8400509A2

公开(公告)日：1987-07-16

申请号：CS50984

申请日：1984-01-23

Applicant: BASF AG

Inventor： ROSSY PHILIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST DR ,  LEHMANN HANS D DR ,  GRIES JOSEF DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER DR

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00

CPC classification number: C07D231/12 ,  C07D233/56 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D249/08 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12

公开(公告)号：DE3535170A1

公开(公告)日：1987-04-16

申请号：DE3535170

申请日：1985-10-02

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  THYES MARCO DR ,  KOENIG HORST PROF DR ,  LEHMANN HANS DIETER PROF DR ,  TRAUT MARTIN DR ,  GRIES JOSEF DR MED ,  ROSSY PHILLIP A DR

IPC: C07D401/04 ,  A61K31/50 ,  A61K31/55 ,  A61P3/02 ,  A61P9/04 ,  A61P9/08 ,  A61P9/10 ,  C07D209/34 ,  C07D215/22 ,  C07D223/16 ,  C07D237/00 ,  C07D403/04 ,  C12N9/99 ,  C07D215/12

Abstract: 2-aryl-3,4-diazabicyclo[4.n.0]-alk-2-en-5-ones of the formula I where m, n, R, R1, R2 and R3 have the stated meanings, are used for the treatment of cardiac insufficiency.

公开(公告)号：DE3524743A1

公开(公告)日：1987-01-15

申请号：DE3524743

申请日：1985-07-11

Applicant: BASF AG

Inventor： STEINER GERD DR ,  THYES MARCO DR

IPC: C07D333/00 ,  C07D409/14 ,  C07D495/14 ,  C07D495/12

公开(公告)号：AT17248T

公开(公告)日：1986-01-15

申请号：AT83103311

申请日：1983-04-05

Applicant: BASF AG

Inventor： OSTERSEHLT BERND DR ,  FRANKE ALBRECHT DR ,  FRICKEL FRITZ-FRIEDER DR ,  THYES MARCO DR ,  FRIEDRICH LUDWIG DR ,  GRIES JOSEF DR ,  LENKE DIETER DR

IPC: C07D405/12 ,  A61K31/415 ,  A61P1/04 ,  A61P43/00 ,  C07D233/61 ,  C07D521/00

公开(公告)号：DE3263688D1

公开(公告)日：1985-06-13

申请号：DE3263688

申请日：1982-10-28

Applicant: BASF AG

Inventor： KROPP RUDOLF ,  THYES MARCO DR ,  SCHLECKER RAINER DR ,  FRANKE ALBRECHT DR ,  REICHENEDER FRANZ DR ,  AMANN AUGUST DR ,  TESCHENDORF HANS-JUERGEN DR ,  KRETZSCHMAR ROLF DR ,  TRAUT MARTIN DR ,  GRIES JOSEF DR

IPC: A61K31/50 ,  A61P9/02 ,  A61P25/00 ,  A61P25/24 ,  A61P25/26 ,  C07D237/20 ,  C07D237/22