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11.发明专利
公开(公告)号：CA2781521A1
公开(公告)日：2011-06-09
申请号：CA2781521
申请日：2010-06-01
Applicant: ABBOTT LAB
Inventor： BRUNCKO MILAN , DAI YUJIA , DING HONG , DOHERTY GEORGE A , ELMORE STEVEN W , HASVOLD LISA , HEXAMER LAURA , KUNZER AARON , MANTEI ROBERT A , MCCLELLAN WILLIAM J , PARK CHANG H , PARK CHEOL-MIN , PETROS ANDREW M , SONG XIAOHONG , SOUERS ANDREW J , SULLIVAN GERARD M , TAO ZHI-FU , WANG GARY T , WANG LE , WANG XILU , WENDT MICHAEL D , HANSEN TODD M
IPC: C07D209/08 , C07D211/58 , C07D213/74 , C07D213/84 , C07D231/56 , C07D235/06 , C07D277/24 , C07D309/04 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D471/04
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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12.发明专利
公开(公告)号：CA2744708A1
公开(公告)日：2010-06-10
申请号：CA2744708
申请日：2009-12-04
Applicant: ABBOTT LAB
Inventor： BRUNCKO MILAN , DAI YUJIA , DING HONG , DOHERTY GEORGE A , ELMORE STEVEN W , HASVOLD LISA , HEXAMER LAURA , KUNZER AARON R , MANTEI ROBERT A , MCCLELLAN WILLIAM J , PARK CHANG H , PARK CHEOL-MIN , PETROS ANDREW M , SONG XIAOHONG , SOUERS ANDREW J , SULLIVAN GERARD M , TAO ZHI-FU , WANG GARY T , WANG LE , WANG XILU , WENDT MICHAEL D
IPC: C07D405/12 , A61K31/395 , A61K31/496 , A61P35/00 , C07D295/04 , C07D309/00 , C07D401/00 , C07D403/12
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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公开(公告)号：CA2690619A1
公开(公告)日：2009-01-22
申请号：CA2690619
申请日：2008-07-16
Applicant: ABBOTT LAB
Inventor： DAI YUJIA , ZHIQIN JI , MICHAELIDES MICHAEL R
IPC: C07D231/56 , A61K31/416 , A61K31/423 , A61K31/428 , A61P35/00 , C07D261/20 , C07D275/04
Abstract: Compounds that inhibit Aurora-kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
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公开(公告)号：CA2631664A1
公开(公告)日：2007-06-14
申请号：CA2631664
申请日：2006-12-08
Applicant: ABBOTT LAB
Inventor： DAI YUJIA , STEINMAN DOUGLAS H , CURTIN MICHAEL L , FREY ROBIN R , MCCLELLAN WILLIAM J , MICHAELIDES MICHAEL R , HOLMS JAMES H
IPC: C07D487/04 , A61K31/519 , A61P35/00 , C07D495/04
Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating cancer using the compounds are disclosed.
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公开(公告)号：AU2003220437A1
公开(公告)日：2003-10-08
申请号：AU2003220437
申请日：2003-03-20
Applicant: ABBOTT LAB
Inventor： FREY ROBIN R , GUO YAN , JI ZHIQIN , CURTIN MICHAEL , MICHAELIDES MICHAEL R , DAI YUJIA , DAVIDSEN STEVEN K
IPC: C07D495/04 , A61K31/519 , A61P1/04 , A61P3/10 , A61P5/14 , A61P7/10 , A61P9/10 , A61P9/12 , A61P11/00 , A61P17/06 , A61P19/02 , A61P21/04 , A61P25/00 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/06 , A61P43/00 , C07D498/02 , C07D513/04
Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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Patent Agency Ranking
公开(公告)号：DE60000819T2
公开(公告)日：2003-09-04
申请号：DE60000819
申请日：2000-01-27
Applicant: ABBOTT LAB
Inventor： CURTIN L , DAI YUJIA , DAVIDSEN K , HEYMAN R , HOLMES H , MICHAELIDES R , STEINMAN H
IPC: A61K31/341 , A61K31/357 , A61K31/40 , A61K31/421 , A61P1/02 , A61P1/04 , A61P17/02 , A61P19/02 , A61P19/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D207/09 , C07D207/14 , C07D207/48 , C07D263/04 , C07D307/14 , C07D317/28 , A61K31/335
Abstract: Compounds having the formula are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
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公开(公告)号：AT228122T
公开(公告)日：2002-12-15
申请号：AT00905758
申请日：2000-01-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAI YUJIA , DAVIDSEN STEVEN K , HEYMAN HOWARD R , HOLMES JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H
IPC: A61K31/341 , A61K31/357 , A61K31/40 , A61K31/421 , A61P1/02 , A61P1/04 , A61P17/02 , A61P19/02 , A61P19/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D207/09 , C07D207/14 , C07D207/48 , C07D263/04 , C07D307/14 , C07D317/28 , A61K31/335
Abstract: Compounds having the formula are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
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公开(公告)号：AU4340202A
公开(公告)日：2002-06-18
申请号：AU4340202
申请日：2001-10-26
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAI YUJIA , DAVIDSEN STEVEN K , FREY ROBIN R , GUO YAN , HEYMAN HOWARD R , HOLMS JAMES H , JI ZHIQIN , MICHAELIDES MICHAEL R , VASUDEVAN ANIL , WADA CAROL K
IPC: C07C45/29 , C07C45/30 , C07C45/45 , C07C45/51 , C07C45/67 , C07C47/277 , C07C49/255 , C07C59/90 , C07C69/716 , C07C235/14 , C07C235/16 , C07C235/20 , C07C235/74 , C07C235/80 , C07C243/38 , C07C255/54 , C07C255/60 , C07C311/19 , C07C317/32 , C07C317/44 , C07C323/41 , C07C323/60 , C07D209/08 , C07D209/42 , C07D213/30 , C07D213/40 , C07D213/75 , C07D215/38 , C07D231/40 , C07D235/06 , C07D257/04 , C07D263/14 , C07D263/32 , C07D263/58 , C07D271/10 , C07D277/46 , C07D277/56 , C07D277/74 , C07D277/82 , C07D285/08 , C07D295/112 , C07D307/68 , C07D307/85 , C07D317/58 , C07D317/66 , C07D317/68 , C07D413/04 , C07D413/12 , C07D417/04 , C07D491/10
Abstract: Substituted trifluoromethyl ketones, ketooxazoles, ketoamides, ketoesters, and diketones having the formula or therapeutically acceptable salts thereof, are histone deacetylase (HDAC) inhibitors. Preparation of the compounds, compositions containing the compounds, and treatment of diseases using the compounds are disclosed.
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公开(公告)号：BR0007278A
公开(公告)日：2001-11-27
申请号：BR0007278
申请日：2000-01-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAI YUJIA , DAVIDSEN STEVEN K , HEYMAN HOWARD R , HOLMES JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H
IPC: A61K31/341 , A61K31/357 , A61K31/40 , A61K31/421 , A61P1/02 , A61P1/04 , A61P17/02 , A61P19/02 , A61P19/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D207/09 , C07D207/14 , C07D207/48 , C07D263/04 , C07D307/14 , C07D317/28 , A61K31/335
Abstract: Compounds having the formula are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
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20.发明专利
公开(公告)号：HK1177202A1
公开(公告)日：2013-08-16
申请号：HK13104084
申请日：2013-04-03
Applicant: ABBOTT LAB
Inventor： BRUNCKO MILAN , DAI YUJIA , DING HONG , DOHERTY GEORGE A , ELMORE STEVEN W , HASVOLD LISA , HEXAMER LAURA , KUNZER AARON , MANTEI ROBERT A , MCCLELLAN WILLIAM J , PARK CHANG H , PARK CHEOL-MIN , PETROS ANDREW M , SONG XIAOHONG , SOUERS ANDREW J , SULLIVAN GERARD M , TAO ZHI-FU , WANG GARY T , WANG LE , WANG XILU , WENDT MICHAEL D , HANSEN TODD M
IPC: C07D20060101
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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