-
公开(公告)号：CA2416740A1
公开(公告)日：2002-03-07
申请号：CA2416740
申请日：2001-08-29
Applicant: ABBOTT LAB
Inventor： LIU GANG , JANOWICK DAVID A , OOST THORSTEN K , XIN ZHILI , PEI ZHONGHUA , SZCZEPANKIEWICZ BRUCE G
IPC: A61P3/10 , C07C209/68 , C07C233/56 , C07C235/74 , C07C237/22 , C07C237/24 , C07C237/42 , C07C271/20 , C07C271/22 , C07C275/24 , C07C311/06 , C07C311/47 , C07C317/40 , C07C323/59 , C07D209/08 , C07D211/20 , C07D241/18 , C07D265/06 , C07D295/135 , C07D295/155 , C07D295/185 , C07D319/18 , A61K31/357 , A61K31/404 , A61K31/535 , C07D209/30 , C07D239/04 , C07D319/10
Abstract: Compound of formula (I) or therapeutically acceptable salts thereof, are protein tyrosine kinase PTP1B inhibitors. Preparation of the compounds, compositions containing the compounds, and treatment of diseases using the compounds are disclosed.
-
公开(公告)号：BG105732A
公开(公告)日：2002-02-28
申请号：BG10573201
申请日：2001-07-25
Applicant: ABBOTT LAB
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , VON GELDERN TOM , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWARDANA INDRANI W , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10
Abstract: The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal. 24 claims
-
公开(公告)号：IS5985A
公开(公告)日：2001-06-28
申请号：IS5985
申请日：2001-06-28
Applicant: ABBOTT LAB CHAD 0377 AP6D 2
Inventor： LINK JAMES , LIU GANG , PEI ZHONGHUA , GELDERN TOM VON , WINN MARTIN , XIN ZHILI , BOYD STEVEN A , JAE HWAN-SOO , LYNCH JOHN K , ZHU GUI-DONG , FREEMAN JENNIFER C , GUNAWAR-DANA INDRANI W , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10
-
公开(公告)号：CA2356320A1
公开(公告)日：2000-07-06
申请号：CA2356320
申请日：1999-12-29
Applicant: ABBOTT LAB
Inventor： LINK JAMES , PEI ZHONGHUA , GUNAWARDANA INDRANI W , LIU GANG , FREEMAN JENNIFER C , ZHU GUI-DONG , BOYD STEVEN A , JAE HWAN-SOO , XIN ZHILI , WINN MARTIN , LYNCH JOHN K , VON GELDERN TOM , STAEGER MICHAEL A
IPC: C07D295/12 , A61K31/16 , A61K31/164 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/4015 , A61K31/404 , A61K31/407 , A61K31/417 , A61K31/438 , A61K31/44 , A61K31/443 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/45 , A61K31/453 , A61K31/454 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/541 , A61P29/00 , A61P37/02 , C07C323/00 , C07C323/62 , C07C323/63 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D207/263 , C07D207/27 , C07D207/273 , C07D207/34 , C07D207/36 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/66 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/36 , C07D217/06 , C07D233/61 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/18 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/16 , C07D295/18 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D411/04 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/10 , C07D487/08 , C07D491/10 , A61K31/10 , C07D295/20 , A61K31/33
Abstract: The present invention relates to novel cinnamide compounds that are useful f or treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
-
公开(公告)号：SG177144A1
公开(公告)日：2012-01-30
申请号：SG2011088143
申请日：2007-11-26
Applicant: ABBOTT LAB
Inventor： SOUERS ANDREW J , GAO JU , HANSEN TODD MATTHEW , IYENGAR RAJESH R , KYM PHILIP R , LIU BO , PEI ZHONGHUA , YEH VINCE , ZHAO GANG , XIN ZHILI
Abstract: INHIBITORS OF DIACYLGLYCEROL o-ACYLTRANSFERASE TYPE 1 ENZYMEAbstractCompounds of formula (I), or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof, Pharmaceutical compositions of formula (I) and related methods of treating or preventing metabolic diseases or conditions. Formula (I)
-
Patent Agency Ranking
公开(公告)号：BRPI0615102A2
公开(公告)日：2011-05-03
申请号：BRPI0615102
申请日：2006-08-25
Applicant: ABBOTT LAB
Inventor： PEI ZHONGHUA , GELDERN THOMAS VON , MADAR DAVID J , LI XIAOFENG , BASHA FATIMA , YONG HONG , LONGENECKER KENTON L , BACKES BRADLEY J , JUDD ANDREW S , MULHERN MATHEW M , STEWART KENT D
IPC: C07C211/40 , A61K31/137 , C07C211/54 , C07C211/62 , C07D213/38 , C07D213/68 , C07D317/64 , C07D487/04
Abstract: The present invention relates to compounds, which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II, as well as hyperglycemia, metabolic syndrome, hyperinsulinemia, obesity, atherosclerosis, various immunomodulatory diseases, and other diseases.
-
公开(公告)号：MX2010005530A
公开(公告)日：2010-06-02
申请号：MX2010005530
申请日：2008-11-20
Applicant: ABBOTT LAB
Inventor： BARNES DAVID M , WU-WONG JINSHYUN RUTH , LI XIAOFENG , HENGEVELD JOHN E , GELDERN THOMAS W VON , BURKALOW JUFANG H , HAIGHT ANGHONY R , MCLAUGHLIN MAUREEN A , NOONAN WILLIAM T , PEI ZHONGHUA
IPC: C07C401/00
Abstract: La presente invención se refiere a compuestos que son activadores del receptor de vitamina D, composiciones que comprenden dichos compuestos, métodos para usar dichos compuestos y composiciones, procesos para preparar dichos compuestos e intermediarios obtenidos durante dichos procesos.
-
公开(公告)号：MX2009005691A
公开(公告)日：2009-08-07
申请号：MX2009005691
申请日：2007-11-26
Applicant: ABBOTT LAB
Inventor： HANSEN TODD MATTHEW , PEI ZHONGHUA , SOUERS ANDREW J , GAO JU , IYENGAR RAJESH R , KYM PHILIP R , LIU BO X , YEH VINCE , ZHAO GANG
IPC: A61K31/415
Abstract: Compuestos de la fórmula (I) (ver fórmula (I)) o una sal, profármaco, sal de profármaco o una combinación de ellas, aceptables para uso farmacéutico. Composiciones farmacéuticas de la fórmula (I) y métodos relacionados para tratar o prevenir enfermedades o condiciones metabólicas.
-
公开(公告)号：DK1560811T3
公开(公告)日：2007-12-10
申请号：DK03774478
申请日：2003-09-15
Applicant: ABBOTT LAB
Inventor： MADAR DAVID , PEI ZHONGHUA , PIREH DAISY , DJURIC STEVAN W , WIEDEMAN PAUL E , YONG HONG , MICHMERHUIZEN MELISSA J , KOPECKA HANA , LI XIAOFENG , LONGENECKER KENTON , SHAM HING L , STEWART KENT D , SZCZEPANKIEWICZ BRUCE G
IPC: C07D207/00 , A61P37/02 , C07D207/16 , C07D207/26 , C07D207/27 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D417/12
Abstract: The present invention relates to compounds of formula I which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases. Or pharmaceutically acceptable salts or prodrugs thereof, wherein X,R,R ,R and R have the definitions given in the description.
-
公开(公告)号：PT1560811E
公开(公告)日：2007-11-14
申请号：PT03774478
申请日：2003-09-15
Applicant: ABBOTT LAB
Inventor： STEWART KENT D , SHAM HING L , MADAR DAVID , PEI ZHONGHUA , PIREH DAISY , DJURIC STEVAN W , WIEDEMAN PAUL E , YONG HONG , MICHMERHUIZEN MELISSA J , KOPECKA HANA , LI XIAOFENG , LONGENECKER KENTON , SZCZEPANKIEWICZ BRUCE G
IPC: C07D207/00 , A61P37/02 , C07D207/16 , C07D207/26 , C07D207/27 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D417/12
-
-
-
-
-
-
-
-
-
Search Results
95
records
(took 0.021 seconds)
