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公开(公告)号：AU6205700A
公开(公告)日：2001-01-22
申请号：AU6205700
申请日：2000-07-05
Applicant: VERTEX PHARMA
Inventor： LAUFFER DAVID , MULLICAN MICHAEL
IPC: A61K31/426 , A61K31/4406 , A61K31/4409 , A61K31/444 , A61K38/27 , A61P9/10 , A61P19/00 , A61P19/08 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/14 , A61P25/16 , A61P29/00 , C07D213/30 , C07D213/40 , C07D277/28 , A61K31/4427
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公开(公告)号：AU5912900A
公开(公告)日：2001-01-22
申请号：AU5912900
申请日：2000-07-05
Applicant: VERTEX PHARMA
Inventor： LAUFFER DAVID , MULLICAN MICHAEL
IPC: A61K31/439 , A61K38/22 , A61P3/10 , A61P19/00 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/04 , A61P25/14 , A61P25/16 , A61P25/28 , A61P39/00 , A61P43/00 , C07D453/02 , C07D487/08 , A61K31/395 , A61K31/44
Abstract: The present invention relates to bicylic derivatives for treating or preventing neuronal damage associated with neurological diseases. The invention also provides compositions comprising the compounds of the present invention and methods of utilizing those compositions for treating or preventing neuronal damage.
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公开(公告)号：HUE057527T2
公开(公告)日：2022-05-28
申请号：HUE18207382
申请日：2014-03-12
Applicant: VERTEX PHARMA
Inventor： MAXWELL JOHN , CHARIFSON PAUL , TANG QING , RONKIN STEVEN , JACKSON KATRINA , PIERCE ALBERT , LAUFFER DAVID , LI PAN , GIROUX SIMON , XU JINWANG , MORRIS MARK , COURT JOHN , COTTRELL KEVIN , DENG HONGBO , WAAL NATHAN , GU WENXIN
IPC: C07D403/12 , A61P35/00 , C07D241/44 , C07D405/12 , C07D413/04 , C07D417/12
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公开(公告)号：BRPI0921509A2
公开(公告)日：2016-03-08
申请号：BRPI0921509
申请日：2009-11-18
Applicant: VERTEX PHARMA
Inventor： LAUFFER DAVID , SHANNON DEAN , LIANG JIANGLIN , LI PAN
IPC: C07D513/04 , A61K31/433
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公开(公告)号：AU2010254055B2
公开(公告)日：2016-01-14
申请号：AU2010254055
申请日：2010-05-27
Applicant: VERTEX PHARMA
Inventor： LAUFFER DAVID , LI PAN , MCGINTY KIRA
IPC: C07D513/04 , A61K31/47 , A61P35/00
Abstract: The present invention relates to compounds of formula (I), which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula (I) and methods of using the compositions in the treatment of proliferative disorders.
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Patent Agency Ranking
公开(公告)号：PT2435443E
公开(公告)日：2013-10-31
申请号：PT10721904
申请日：2010-05-27
Applicant: VERTEX PHARMA
Inventor： LI PAN , LAUFFER DAVID , MCGINTY KIRA
IPC: C07D513/04 , A61K31/47 , A61P35/00
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公开(公告)号：DK2435443T3
公开(公告)日：2013-10-28
申请号：DK10721904
申请日：2010-05-27
Applicant: VERTEX PHARMA
Inventor： LAUFFER DAVID , LI PAN , MCGINTY KIRA
IPC: C07D513/04 , A61K31/47 , A61P35/00
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公开(公告)号：ES2393693T3
公开(公告)日：2012-12-27
申请号：ES09756109
申请日：2009-11-18
Applicant: VERTEX PHARMA
Inventor： LAUFFER DAVID , LI PAN , SHANNON DEAN , LIANG JIANGLIN
IPC: C07D513/04 , A61K31/433
Abstract: Un compuesto que tiene la fórmula: o una sal farmacéuticamente aceptable del mismo.
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公开(公告)号：AU2012203384A8
公开(公告)日：2012-08-02
申请号：AU2012203384
申请日：2012-06-08
Applicant: VERTEX PHARMA
Inventor： SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , GREEN JEREMY , COURT JOHN , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , WANG JIAN , PINDER JOANNE , WANG TIANSHENG , PIERCE ALBERT
IPC: C07D471/04 , C07D519/00
Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：AU2012203384A1
公开(公告)日：2012-06-28
申请号：AU2012203384
申请日：2012-06-08
Applicant: VERTEX PHARMA
Inventor： SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , GREEN JEREMY , COURT JOHN , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , WANG JIAN , PINDER JOANNE , WANG TIANSHEN , PIERCE ALBERT
IPC: C07D471/04 , C07D519/00
Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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