Patent search ap:("ABBOTT LAB") AND inv:"YEUNG MING C" Page 3

21.

发明专利
Sulfonamidas que inhiben la proteasa de VIH 未知

公开(公告)号：ES2396761T3

公开(公告)日：2013-02-26

申请号：ES09176641

申请日：2004-11-10

Applicant: ABBOTT LAB

Inventor： FLENTGE CHARLES A , CHEN HUI-JU , DEGOEY DAVID A , FLOSI WILLIAM J , GRAMPOVNIK DAVID J , HUANG PEGGY P , KEMPF DALE J , KLEIN LARRY L , KRUEGER ALLAN C , MADIGAN DAROLD L , RANDOLPH JOHN T , SUN MINGHUA , YEUNG MING C , ZHAO CHEN

IPC: C07D417/06 , A61K31/175 , A61K31/18 , A61K31/195 , A61K31/277 , A61K31/4168 , A61K31/4178 , A61K31/65 , A61K45/06 , A61P31/18 , C07C311/17 , C07D213/30 , C07D213/40 , C07D213/78 , C07D233/32 , C07D233/72 , C07D277/28 , C07D277/46 , C07D277/48 , C07D307/20 , C07D307/42 , C07D401/06 , C07D403/06 , C07D403/10 , C07D405/06 , C07D405/10 , C07D409/06 , C07D417/14 , C07D471/04 , C07D493/04

Abstract: Un compuesto que tiene la formula (IIII) o una forma de sal farmaceuticamente aceptable, estereoisomero, ester, sal de un ester, o una combinacion de losmismos, en la que X es O, S o NH; R es alquilo, alquenilo, cicloalquilo, cicloalquenilo, cicloalquilalquilo, cicloalquenilalquilo, arilalquilo oheteroarilalquilo; en el que cada R esta sustituido con 0, 1 o 2 sustituyentes seleccionados entre el grupo que consiste en alquilo,alquenilo, alquinilo, ciano, halo, formilo, nitro, hidroxi, alcoxi, -NH2, -N(H)alquilo, N(alquilo)2, -C(>=O)OH, -C(>=O)Oalquilo, haloalquilo, hidroxialquilo y alcoxialquilo; R1 es ORa, -OSO2Ra, -OSO3Ra, -OPO3Ra, -OC(>=O)C(H)(R1a) NRaRb o -OC(>=O)C(H)(R1a)N(H)C(O) ORa; R1 es ORa, -OSO2Ra, -OSO3Ra, -OPO3Ra, -OC(>=O)C(H)(R1a)NRaRb u -OC(>=O)C(H)(R1a)N(H)C(O)ORa; R1a es hidrogeno, alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquenilo, arilo, arilalquilo, heteroarilo oheteroarilalquilo.

22.

发明专利
HIV PROTEASE INHIBITING SULFONAMIDES 未知

公开(公告)号：HK1143579A1

公开(公告)日：2011-01-07

申请号：HK10109889

申请日：2010-10-19

Applicant: ABBOTT LAB

Inventor： FLENTGE CHARLES A , CHEN HUI-JU , DEGOEY DAVID A , FLOSI WILLIAM J , GRAMPOVNIK DAVID J , HUANG PEGGY P , KEMPF DALE J , KLEIN LARRY L , KRUEGER ALLAN C , MADIGAN DAROLD L , RANDOLPH JOHN T , SUN MINGHUA , YEUNG MING C , ZHAO CHEN

IPC: A61K20060101 , A61K31/175 , A61K31/18 , A61K31/195 , A61K31/277 , A61K31/4168 , A61K31/65 , A61K45/06 , A61P20060101 , C07C20060101 , C07C311/17 , C07D20060101 , C07D213/30 , C07D213/40 , C07D213/78 , C07D233/32 , C07D233/72 , C07D277/28 , C07D277/46 , C07D277/48 , C07D307/20 , C07D307/42 , C07D401/06 , C07D403/06 , C07D403/10 , C07D405/06 , C07D405/10 , C07D409/06 , C07D417/06 , C07D417/14 , C07D471/04 , C07D493/04

Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

23.

发明专利
未知

公开(公告)号：BR0010555A

公开(公告)日：2003-09-23

申请号：BR0010555

申请日：2000-10-10

Applicant: ABBOTT LAB

Inventor： MARING CLARENCE J , GIRANDA VINCENT L , KEMPF DALE J , STOLL VINCENT S , SUN MINGHUA , ZHAO CHEN , GU YU GUI , HANESSIAN STEPHEN , WANG GARY T , KRUEGER ALLAN C , CHEN HUI-JU , CHEN YUANWEI , DEGOEY DAVID A , FLOSI WILLIAM J , GRAMPOVNIK DAVID J , KATI WARREN M , KENNEDY APRIL L , KLEIN LARRY L , LIN ZHEN , MADIGAN DAROLD L , MCDANIEL KEITH F , MUCHMORE STEVEN W , SHAM HING L , STEWART KENT D , TU NOAH P , WAGENAAR FRANK L , WANG SHELDON , WIEDEMAN PAUL E , XU YIBO , YEUNG MING C , BAYRAKDARIAN MALKEN , LUO XUEHONG

IPC: C07D401/12 , A61K31/357 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/405 , A61K31/415 , A61K31/4155 , A61K31/4178 , A61K31/42 , A61K31/422 , A61K31/425 , A61K31/427 , A61K31/4439 , A61K31/5377 , A61K31/66 , A61K31/662 , A61P31/00 , A61P31/12 , A61P31/16 , A61P43/00 , C07D20060101 , C07D207/00 , C07D207/12 , C07D207/16 , C07D207/26 , C07D207/32 , C07D207/327 , C07D207/38 , C07D207/46 , C07D303/16 , C07D403/04 , C07D403/06 , C07D405/04 , C07D405/06 , C07D407/06 , C07D407/12 , C07D409/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D521/00 , C07F9/40 , C07F9/572

24.

发明专利
未知

公开(公告)号：TR200003065T2

公开(公告)日：2001-02-21

申请号：TR200003065

申请日：1999-04-12

Applicant: ABBOTT LAB

Inventor： MARING CLARENCE J , GU YU-GUI , CHEN HUI-JU , CHEN YUANWEI , DEGOEY DAVID A , FLOSI WILLAIM J , GIRANDA VINCENT L , GRAMPOVNIK DAVID J , KATI WARREN M , KEMPF DALE J , KLEIN LARRY L , KRUEGER ALLAN C , LIN ZHEN , MADIGAN DAROLD L , MCDANIEL KEITH F , MUCHMORE STEVEN W , SHAM HING L , STEWART KENT D , STOLL VINCENT S , SUN MINGHUA , WANG GARY T , WANG SHELDON , XU YIBO , YEUNG MING C , ZHAO CHEN , KENNEDY APRIL

IPC: A61K31/401 , A61K31/4025 , A61K31/41 , A61K31/4155 , A61K31/4178 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/5377 , A61P31/16 , A61P43/00 , C07D207/16 , C07D207/32 , C07D207/325 , C07D207/327 , C07D401/12 , C07D403/04 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/06 , C07D521/00 , C07F9/572 , A61K31/40

25.

发明专利
Amino-lipopeptide antifungal agents 未知

公开(公告)号：AU4059197A

公开(公告)日：1998-03-06

申请号：AU4059197

申请日：1997-08-11

Applicant: ABBOTT LAB

Inventor： LARTEY PAUL A , LI LEPING , KLEIN LARRY L , LEONE CHRISTINE L , THOMAS SHEELA A , YEUNG MING C , DEGOEY DAVID A , .RAMPOVNIK DAVID J

IPC: A61K38/00 , C07K7/56 , A61K38/12

Abstract: Disclosed are novel antifungal agents having the formula: I or a pharmaceutically acceptable acid, ester or prodrug thereof, wherein preferred compounds include those compounds wherein R1 is selected from the group consisting of -NH2; R2 is selected from the group consisting of hydrogen, fluoro, and hydroxyl; R3 is selected from the group consisting of -CH2(p-C6H4)3O(CH2)3CH3, -CH2(p-C6H4)O(CH2)6CH3, -COO(p-C6H4)O(CH2)6CH3, -CO(Piperazinyl)(p-C6H4)2OCH3, -CO(p-C6H4)O(CH2)6CH3, -CO(p-C6H4)(Piperazinyl)(p-C6H4)O(CH2)4CH3, -CO(p-C6H4)(Piperazinyl)(p-C6H4)O(CH2)6CH3, -CO(p-C6H4)(Piperazinyl)(p-C6H4)OCH3, and -CO(p-C6H4)(Piperazinyl)O(CH2)6CH3; and R4 is selected from the group consisting of -CH(OH)CH3, -CH2OH, -CH2CH3, -CH2CH2CH2NH2, -CH2(CH2)NH2, -CH2NH2, -CH2(CH2)2(NH)C=(NH)-NH2, -CH3, -CH2(Ph)OH, hydrogen, -CH2CH2COOH, and -CH2COOH. Also disclosed are pharmaceutical compositions containing such compounds and the use of the same in the treatment of fungal infections.