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公开(公告)号：ZA971179B
公开(公告)日：1998-01-15
申请号：ZA971179
申请日：1997-02-12
Applicant: ABBOTT LAB
Inventor： WINN MARTIN , BOYD STEVEN A , HUTCHINS CHARLES W , JAE HWAN-SOO , TASKER ANDREW S , GELDERN THOMAS W VON , KESTER JEFFREY A , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , HENRY JR KENNETH J , LIU GANG , WITTENBERGER STEVEN J , KING STEVEN A
IPC: A61K20060101 , C07D20060101 , C07F20060101 , C07D , A61K , C07F
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52.发明专利
公开(公告)号：CA2245587A1
公开(公告)日：1997-08-21
申请号：CA2245587
申请日：1997-02-12
Applicant: ABBOTT LAB
Inventor： LIU GANG , HENRY KENNETH J , SZCZEPANKIEWICZ BRUCE G , SORENSEN BRYAN K , KING STEVEN A , WITTENBERGER STEVEN J , BOYD STEVEN A , WINN MARTIN , KESTER JEFFREY A , JAE HWAN-SOO , HUTCHINS CHARLES W , VON GELDERN THOMAS W , TASKER ANDREW S
IPC: A61K31/395 , A61K31/40 , A61K31/4015 , A61K31/4035 , A61K31/41 , A61K31/415 , A61K31/4164 , A61K31/4166 , A61K31/421 , A61K31/425 , A61K31/435 , A61K31/4439 , A61K31/454 , A61K31/495 , A61K31/506 , A61K31/675 , A61P1/00 , A61P1/04 , A61P7/02 , A61P9/00 , A61P9/04 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/12 , A61P25/06 , A61P43/00 , C07D207/16 , C07D211/60 , C07D401/04 , C07D403/04 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D419/14 , C07D453/02 , C07D471/04 , C07D491/04 , C07F9/572
Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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公开(公告)号：AU650491B2
公开(公告)日：1994-06-23
申请号：AU8771591
申请日：1991-11-08
Applicant: ABBOTT LAB
Inventor： KEMPF DALE , CODACOVI LYNN M , SHAM HING L , WITTENBERGER STEVEN J , NORBECK DANIEL W , PLATTNER JACOB J , ZHAO CHEN , SOWIN THOMAS J
IPC: A61K31/42 , A61K31/421 , A61K31/425 , A61K31/426 , A61K31/427 , A61K31/435 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4427 , A61K31/443 , A61K31/444 , A61K38/00 , A61P31/12 , A61P31/18 , A61P43/00 , C07C53/134 , C07C211/00 , C07C215/18 , C07C215/20 , C07C215/28 , C07C215/30 , C07C215/80 , C07C219/18 , C07C233/40 , C07C237/10 , C07C237/22 , C07C269/04 , C07C271/02 , C07C271/16 , C07C271/20 , C07C271/22 , C07C271/34 , C07C275/24 , C07D20060101 , C07D213/00 , C07D213/26 , C07D213/30 , C07D213/34 , C07D213/36 , C07D213/40 , C07D213/54 , C07D213/56 , C07D213/61 , C07D213/75 , C07D213/79 , C07D215/20 , C07D233/54 , C07D233/84 , C07D235/14 , C07D235/16 , C07D237/10 , C07D239/26 , C07D241/12 , C07D261/08 , C07D261/12 , C07D263/20 , C07D263/32 , C07D277/20 , C07D277/24 , C07D277/28 , C07D277/30 , C07D277/32 , C07D277/34 , C07D277/36 , C07D277/40 , C07D277/42 , C07D277/56 , C07D295/02 , C07D295/13 , C07D295/205 , C07D295/215 , C07D303/36 , C07D307/34 , C07D307/42 , C07D307/66 , C07D333/16 , C07D333/36 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D521/00 , C07K1/113 , C07K5/06 , C07K5/065 , C07K5/08 , C07K14/81 , C07D213/70 , C07D213/74 , C07D213/32 , C07D295/135 , C07D491/048 , C07D277/48 , C07D233/16 , C07D233/42 , C07D307/12 , C07D231/12 , C07D307/28 , C07D305/06 , C07C233/36 , C07C271/52 , C07C233/38 , C07K5/02 , A61K37/64
Abstract: An intermediate of the formula: and an intermediate of the formula: or an acid addition salt thereof.M
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公开(公告)号：PT99545A
公开(公告)日：1992-09-30
申请号：PT9954591
申请日：1991-11-19
Applicant: ABBOTT LAB
Inventor： SHAM HING L , PLATTNER JACOB J , NORBECK DANIEL W , KEMPF DALE J , CODACOVI LYNN M , WITTENBERGER STEVEN J , ZHAO CHEN
IPC: A61K31/42 , A61K31/421 , A61K31/425 , A61K31/426 , A61K31/427 , A61K31/435 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4427 , A61K31/443 , A61K31/444 , A61K38/00 , A61P31/12 , A61P31/18 , A61P43/00 , C07C53/134 , C07C211/00 , C07C215/18 , C07C215/20 , C07C215/28 , C07C215/30 , C07C215/80 , C07C219/18 , C07C233/40 , C07C237/10 , C07C237/22 , C07C269/04 , C07C271/02 , C07C271/16 , C07C271/20 , C07C271/22 , C07C271/34 , C07C275/24 , C07D20060101 , C07D213/00 , C07D213/26 , C07D213/30 , C07D213/34 , C07D213/36 , C07D213/40 , C07D213/54 , C07D213/56 , C07D213/61 , C07D213/75 , C07D213/79 , C07D215/20 , C07D233/54 , C07D233/84 , C07D235/14 , C07D235/16 , C07D237/10 , C07D239/26 , C07D241/12 , C07D261/08 , C07D261/12 , C07D263/20 , C07D263/32 , C07D277/20 , C07D277/24 , C07D277/28 , C07D277/30 , C07D277/32 , C07D277/34 , C07D277/36 , C07D277/40 , C07D277/42 , C07D277/56 , C07D295/02 , C07D295/13 , C07D295/205 , C07D295/215 , C07D303/36 , C07D307/34 , C07D307/42 , C07D307/66 , C07D333/16 , C07D333/36 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D521/00 , C07K1/113 , C07K5/06 , C07K5/065 , C07K5/08 , C07K14/81 , C07C , C07D , A61K
Abstract: An intermediate of the formula: and an intermediate of the formula: or an acid addition salt thereof.M
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公开(公告)号：CA2573688C
公开(公告)日：2013-05-28
申请号：CA2573688
申请日：2005-07-08
Applicant: ABBOTT LAB
Inventor： BUCKLEY MICHAEL J , JI JIANGUO , ZHANG GEOFF G , HENRY RODGER F , WANG WEILI W , WAYNE GREG S , LI WENKE , TOWNE TIMOTHY B , WITTENBERGER STEVEN J , HANNICK STEVEN M , KOTECKI BRIAN J , MACRI BRYAN S , ROBBINS TIMOTHY A
IPC: C07D487/04 , A61K31/4439
Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
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Patent Agency Ranking
公开(公告)号：UA97639C2
公开(公告)日：2012-03-12
申请号：UAA200811465
申请日：2007-02-16
Applicant: ABBOTT LAB
Inventor： COWART MARLON D , ZHAO CHEN , SUN MINGHUA , BLACK LAWRENCE A , ZHENG GUO ZHU , GREGG ROBERT J , ZHANG GEOFF G Z , SHEIKH AHMAD Y , LOU XIAOCHUN , HENRY RODGER F , BARNES DAVID M , KOLACZKOWSKI LAWRENCE , HAIGHT ANTHONY R , CHANG SOU-JEN , WITTENBERGER STEVEN J , FICKES MICHAEL G
IPC: C07D487/04 , A61K31/407
Abstract: Раскрытыоктагидропирроло[3,4-b]пиррольныепроизводныеформулы I и II, пригодныедлялечениясостоянийилирасстройств, которыепредотвращаютсяилиоблегчаютсяс помощьюлигандоврецепторагистамина-3.Раскрытыоктагидропирроло[3,4-b]пиррольныесоединения, применениетакихсоединений, композиции, содержащиеэтисоединения, испособыполучениятакихсоединений.
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公开(公告)号：HU226888B1
公开(公告)日：2010-01-28
申请号：HU9901580
申请日：1997-02-12
Applicant: ABBOTT LAB
Inventor： BOYD STEVEN A , HENRY KENNETH JR , HUTCHINS CHARLES W , JAE HWAN-SOO , KESTER JEFFREY A , KING STEVEN A , LIU GANG , SORENSEN BRYAN K , SZCZEPANKIEWICZ BRUCE G , TASKER ANDREW S , WINN MARTIN , WITTENBERGER STEVEN J , VON GELDERN THOMAS W
IPC: A61K31/40 , A61K31/4025 , A61K31/435 , A61K31/4439 , A61P9/00 , A61P35/00 , C07D207/04 , C07D207/16 , C07D211/06 , C07D401/04 , C07D405/04 , C07D405/14 , C07F9/572 , C07F9/59
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公开(公告)号：ZA200901558B
公开(公告)日：2010-01-27
申请号：ZA200901558
申请日：2009-03-04
Applicant: ABBOTT LAB
Inventor： BUCKLEY MICHAEL J , HENRY RODGER F , KOTECKI BRIAN J , MARCI BRYAN S , TOWNE TIMOTHY B , WANG WEILI W , ZHANG GEOFF G , HANNICK STEVEN M , JI JIANGUO , LI WENKE , ROBBINS TIMOTHY A , WITTENBERGER STEVEN J , WAYNE GREG S
IPC: A61K20100101 , A61K31/4439 , C07D20100101 , C07D487/04
Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
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公开(公告)号：CA2342217C
公开(公告)日：2009-12-15
申请号：CA2342217
申请日：1999-09-13
Applicant: ABBOTT LAB
Inventor： KING STEVEN A , BARNES DAVID M , PLAGGE FREDERICK A , JI JIANGUO , ZHANG JI , WITTENBERGER STEVEN J
IPC: C07C201/12 , C07D317/64 , C07B53/00 , C07B61/00 , C07C205/02 , C07C251/18 , C07D263/52 , C07D405/04
Abstract: The present invention relates to producing stereoselective nitro compounds b y reacting a dicarbonyl compound with a nitrostyrene compound in the presence of a catalyst complex and a base.
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公开(公告)号：ZA200700510B
公开(公告)日：2009-07-29
申请号：ZA200700510
申请日：2007-01-17
Applicant: ABBOTT LAB
Inventor： BUCKLEY MICHAEL J , ZHANG GEOFF G , WANG WEILI W , WENKE LI , WITTENBERGER STEVEN J , KOTECKI BRIAN J , ROBBINS TIMOTHY A , JIANGUO JI , HENRY RODGER F , WAYNE GREG S , TOWNE TIMOTHY B , HANNICK STEVEN M , MARCI BRYAN S
IPC: A61K20090101 , A61K31/4439 , C07D20090101 , C07D487/04
Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
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