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公开(公告)号：NO996579L
公开(公告)日：2000-01-24
申请号：NO996579
申请日：1999-12-30
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , A61K31/16
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
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公开(公告)号：NO996579A
公开(公告)日：2000-01-24
申请号：NO996579
申请日：1999-12-30
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , A61K31/16
CPC classification number: C07D207/404 , C07C311/05 , C07C311/18 , C07C317/28 , C07C323/47 , C07C323/62 , C07D207/408 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12
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公开(公告)号：ZA9806828B
公开(公告)日：1999-01-29
申请号：ZA9806828
申请日：1998-07-30
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F JR , FLORJANCIC ALAN S , GIESLER JAMIE R , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07C , A61K , C07D
CPC classification number: C07D207/404 , C07C311/05 , C07C311/18 , C07C317/28 , C07C323/47 , C07C323/62 , C07D207/408 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12
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公开(公告)号：ZA9820B
公开(公告)日：1998-07-02
申请号：ZA9820
申请日：1998-01-02
Applicant: ABBOTT LAB
Inventor： DAVIDSEN STEVEN K , SHEPPARD GEORGE S , HOLMS JAMES H , FLORJANCIC ALAN S , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , XU LIANHONG , GUO YAN , SUMMERS JAMES B
IPC: A61K31/395 , A61K31/40 , A61K31/404 , A61K31/4188 , A61K31/427 , A61K31/4427 , A61K31/4523 , A61K31/553 , A61K38/00 , A61K38/55 , A61P1/02 , A61P7/00 , A61P11/06 , A61P19/02 , A61P19/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D225/06 , C07D245/02 , C07D245/06 , C07D267/00 , C07D273/01 , C07D413/04 , C07D413/06 , C07D413/12 , C07D417/06 , C07D417/12 , C07D487/08 , C07K5/078 , C07D , A61K
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公开(公告)号：NO953957L
公开(公告)日：1995-11-21
申请号：NO953957
申请日：1995-10-05
Applicant: ABBOTT LAB
Inventor： MICHAELIDES MICHAEL R , HONG YUFENG
IPC: A61K31/435 , A61P1/08 , A61P9/00 , A61P25/00 , A61P25/18 , A61P25/24 , A61P25/26 , A61P25/28 , A61P39/02 , C07D491/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D513/04 , A61K31/38
Abstract: A tetracyclic compound of the formula: wherein A and the atoms to which it is attached and the optional double bond represent a mono- or di-heterocyclic ring selected from: wherein R1, R2, R3, R4 and X are specifically defined, which compounds are useful in the treatment of dopamine-related neurological, psychological and cardiovascular disorders as well as in the treatment of substance abuse and other addictive behavior disorders, cognitive impairment and attention deficit disorder.
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Patent Agency Ranking
公开(公告)号：ECSP13012993A
公开(公告)日：2014-01-31
申请号：ECSP13012993
申请日：2013-06-13
Applicant: ABBOTT LAB
Inventor： WOLLER KEVIN ROGER , CURTIN L MICHAEL , MACK HELMUT , MICHAELIDES MICHAEL R , HANSEN TODD M , VASUDEVAN ANIL , SORENSEN BRYAN K , HEYMAN HOWARD R , CLARK RICHARD F , SHAH OMAR J , TSE CHRIS , SWEIS RAMZI , PLIUSHCHEV MARINA A
IPC: C07D209/44 , A61K31/4035 , A61K31/407 , A61P9/10 , A61P35/00 , C07D403/12 , C07D407/12 , C07D407/14 , C07D413/12 , C07D471/04
Abstract: Compuestos que inhiben la actividad de la NAMPT, composiciones que contienen los compuestos y métodos para tratar enfermedades en las cuales se expresa la NAMPT. Compuestos que inhiben la actividad de la ROCK, composiciones que contienen los compuestos y métodos para tratar enfermedades en las cuales se expresa la ROCK.
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公开(公告)号：CA2532982C
公开(公告)日：2013-11-26
申请号：CA2532982
申请日：2004-07-26
Applicant: ABBOTT LAB
Inventor： BETSCHMANN PATRICK , BURCHAT ANDREW F , CALDERWOOD DAVID J , CURTIN MICHAEL L , DAVIDSEN STEVEN K , DAVIS HEATHER M , FREY ROBIN R , HEYMAN HOWARD R , HIRST GAVIN C , HRNCIAR PETER , MICHAELIDES MICHAEL R , MUCKEY MELANIE A , RAFFERTY PAUL , WADA CAROL K
IPC: C07D495/04 , A61K31/4355 , A61K31/4365 , A61P35/00 , C07D491/04 , C07D498/04
Abstract: Compounds having the formula: (I), are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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68.发明专利
公开(公告)号：CO6382131A2
公开(公告)日：2012-02-15
申请号：CO11075260
申请日：2011-06-16
Applicant: ABBOTT LAB
Inventor： MICHAELIDES MICHAEL R , CURTIN MICHAEL L , FREY ROBIN R
IPC: A61K31/4365 , A61P35/00 , C07D495/04
Abstract: Compuestos que inhiben proteína quinasas, tales como aurora-quinasas y las familias de quinasas VEGFR y PDGFR, con un perfil de seguridad mejorado debido a unabaja inhibición de CYP3A4, composiciones que contienen los compuestos y métodos de tratamiento de enfermedades usando los compuestos.
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公开(公告)号：HK1149757A1
公开(公告)日：2011-10-14
申请号：HK11103975
申请日：2011-04-19
Applicant: ABBOTT LAB
Inventor： DAI YUJIA , DAVIDSEN STEVEN K , ERICSSON ANNA M , HARTANDI KRESNA , JI ZHIQIN , MICHAELIDES MICHAEL R
IPC: A61K20060101 , A61K31/416 , A61K31/42 , A61K31/4709 , A61P20060101 , A61P35/00 , C07D20060101 , C07D231/56 , C07D261/20 , C07D413/02
Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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70.发明专利
公开(公告)号：DOP2011000153A
公开(公告)日：2011-06-30
申请号：DO2011000153
申请日：2011-05-24
Applicant: ABBOTT LAB
Inventor： MICHAELIDES MICHAEL R , CURTIN MICHAEL L , FREY ROBIN R
Abstract: Compuestos que inhiben proteína quinasas, tales como aurora-quinasas y las familias de quinasas VEGFR y PDGFR, con un perfil de seguridad mejorado debido a una baja inhibición de CYP3A4, composiciones que contienen los compuestos y métodos de tratamiento de enfermedades usando los compuestos.
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