公开(公告)号：US20170059488A1

公开(公告)日：2017-03-02

申请号：US15236510

申请日：2016-08-15

Applicant: University of Geneva

Inventor： Jean-Pierre WOLF ,  Luigi BONACINA ,  Gustavo Alexandre SUBTIL SOUSA

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  A61B5/0071 ,  A61B5/0075 ,  G01J3/427 ,  G01J3/4406 ,  G01N21/636 ,  G01N21/6402 ,  G01N21/6408 ,  G01N2201/06113

Abstract: This invention concerns the field of sample identification, in particular a method and apparatuses for identifying or discriminating biological species from non biological species, both as individual particles and as components of a composition, by pump-probe fluorescence spectroscopy for time-resolved detection or imaging. The method uses the finding that the UV-induced fluorescence of biological molecules is varied, in particular is depleted, by the addition of visible radiation, whereas this does not occur with non-biological organic molecules. The invention discriminates the fluorescence signals of bio and non-bio particles or species using a differential approach, i.e. the comparison. of the total fluorescence recorded with and without additional visible radiation. This allows to discriminate biological particles comprising aromatic amino-acids (AA), like peptides, proteins, bacteria, viruses, pollens, spores, etc., from non-biological particles, like aromatic (AH) or polyaromatic hydrocarbons (PAH), carbonaceous aerosols, soot, etc.

Abstract translation: 本发明涉及样品鉴定领域，特别是用于通过用于时间分辨检测或成像的泵浦探针荧光光谱鉴定或区分来自非生物物种的生物物种的方法和装置，作为单个颗粒和组合物的组分 。 该方法使用通过添加可见光辐射来改变生物分子的紫外线诱导荧光，特别是耗尽，而非生物有机分子不会发生这种发现。 本发明使用差分方法即比较来区分生物和非生物颗粒或物种的荧光信号。 记录有和没有额外的可见光的总荧光。 这允许从非生物颗粒如芳族（AH）或多芳族烃（PAH），含碳的物质（PAH）中区分包含芳族氨基酸（AA），如肽，蛋白质，细菌，病毒，花粉，孢子等的生物颗粒 气溶胶，烟灰等

公开(公告)号：US09448112B2

公开(公告)日：2016-09-20

申请号：US13931091

申请日：2013-06-28

Applicant: Spectro Scientific, Inc.

Inventor： James Greer ,  Robert J. Guthrie ,  John Coates

IPC: G01N21/00 ,  G01J3/42 ,  G01J3/02 ,  G01J3/10 ,  G01J3/427 ,  G01N21/03 ,  G01N21/31 ,  G01N21/3577 ,  G01N21/33

CPC classification number: G01J3/42 ,  G01J3/0218 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/0294 ,  G01J3/10 ,  G01J3/427 ,  G01J2003/106 ,  G01N21/0303 ,  G01N21/31 ,  G01N21/33 ,  G01N21/3577

Abstract: A simple and compact apparatus, and a method, for determining the characteristics of a number of fluids used in the truck and automotive industries including coolant, bio-diesel, gas-ethanol and diesel engine fluid (DEF). The apparatus includes a sample container providing optical paths of different lengths for making measurements on a sample. The dual path length design allows the apparatus to capture both NIR and UV spectral ranges. The qualitative and quantitative properties of the fluid under test are compared to test results under normal conditions or to the properties of unused fluid. Two light sources are used within a spectrometer with each source being associated with a different optical path length.

Abstract translation: 用于确定卡车和汽车工业中使用的许多流体的特性的简单且紧凑的装置和方法，包括冷却剂，生物柴油，汽油 - 乙醇和柴油机流体（DEF）。 该装置包括提供不同长度的光路以便对样品进行测量的样品容器。 双路径长度设计允许设备捕获NIR和UV光谱范围。 将待测流体的定性和定量性质与正常条件下的试验结果或未使用流体的性质进行比较。 在光谱仪中使用两个光源，每个光源与不同的光路长度相关联。

公开(公告)号：US20160231229A1

公开(公告)日：2016-08-11

申请号：US15023721

申请日：2014-09-17

Applicant: Vaisala Oyj

Inventor： Veli-Pekka Viitanen

IPC: G01N21/25 ,  G01N21/31

CPC classification number: G01N21/255 ,  G01J3/26 ,  G01J3/42 ,  G01J3/427 ,  G01N21/274 ,  G01N21/31 ,  G01N21/3504 ,  G01N33/2841 ,  G01N2021/3536 ,  G01N2201/068 ,  G01N2201/12715

Abstract: The present invention concerns a method and system for gas concentration measurement of gas or gas mixtures dissolved in liquids. A gas or gas mixture dissolved in a liquid sample is extracted from the liquid sample using an extraction system and conducted into a measurement chamber. Then a measurement signal is generated by means of a radiant source and the measurement signal is directed to a measurement object in a measurement chamber containing the gas or gas mixture to be measured. The measurement signal is filtered using at least two wavelengths, whereupon the filtering is preferably implemented by means of an electrically tunable, short-resonator Fabry-Perot interferometer. Then the filtered measurement signals are detected my means of a detector.

Abstract translation: 本发明涉及溶解在液体中的气体或气体混合物的气体浓度测量方法和系统。 使用提取系统从液体样品中提取溶解在液体样品中的气体或气体混合物，并将其导入测量室。 然后通过辐射源产生测量信号，并且测量信号被引导到包含要测量的气体或气体混合物的测量室中的测量对象。 使用至少两个波长对测量信号进行滤波，因此滤波优选通过电可调谐的短谐振器法布里 - 珀罗干涉仪实现。 然后用检测器的装置检测滤波后的测量信号。

公开(公告)号：US09347882B2

公开(公告)日：2016-05-24

申请号：US13737279

申请日：2013-01-09

Applicant: Molecular Devices, LLC

Inventor： Josef J. Atzler ,  Bernhard Schinwald

IPC: G01N21/76 ,  G01N21/64 ,  G01J3/02 ,  G01J3/10 ,  G01J3/427 ,  G01J3/44 ,  G01N21/17

CPC classification number: G01N21/64 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0232 ,  G01J3/0235 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/427 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6445 ,  G01N21/645 ,  G01N21/763 ,  G01N2021/1738 ,  G01N2021/6415 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/6482 ,  G01N2201/024 ,  G01N2201/0618 ,  G01N2201/062 ,  G01N2201/0621 ,  G01N2201/0692 ,  G01N2201/0696

Abstract: Systems and methods for measuring a target in a sample, the target being capable of generating an emitted light in response to an excitation light. In an example system, an excitation light source generates the excitation light along an excitation optical path. An attenuation filter arrangement selectively adds an attenuation filter to the excitation optical path. The attenuation filter attenuates the excitation light by a corresponding attenuation factor. The excitation light exits the attenuation filter arrangement along the excitation optical path to illuminate the sample. A light energy detector receives the emitted light generated in response to the excitation light, and outputs a measured signal level corresponding to an emitted light level. If the light energy detector indicates an overflow, signal measurement is repeated with attenuation filters of increasing attenuation factors until the measured signal level does not overflow.

Abstract translation: 用于测量样本中的目标的系统和方法，所述目标能够响应于激发光产生发射的光。 在示例性系统中，激发光源沿着激发光路产生激发光。 衰减滤波器装置选择性地将衰减滤波器添加到激励光路。 衰减滤波器通过相应的衰减因子衰减激发光。 激发光沿着激发光路离开衰减滤光器装置以照亮样品。 光能检测器接收响应于激发光产生的发射光，并且输出与发射的光级相对应的测量信号电平。 如果光能检测器指示溢出，则使用增加衰减因子的衰减滤波器重复信号测量，直到测量信号电平不会溢出。

公开(公告)号：US09239262B2

公开(公告)日：2016-01-19

申请号：US13537414

申请日：2012-06-29

Applicant: William Ross Rapoport ,  James Kane ,  Carsten Lau

Inventor： William Ross Rapoport ,  James Kane ,  Carsten Lau

IPC: F21V9/16 ,  G01J1/58 ,  G01T1/10 ,  G21H3/02 ,  G21K5/00 ,  H01J65/06 ,  H01J65/08 ,  G01J3/427 ,  G01N21/64 ,  G07D7/12

CPC classification number: G01J3/427 ,  G01N21/64 ,  G01N2021/6421 ,  G07D7/1205

Abstract: Methods and apparatus for article authentication include an exciting radiation generator that exposes an area of the article to exciting radiation, and at least two radiation detectors that detect emitted radiation from the area in a first band and in a second band that does not overlap the first band. The first band corresponds with a first emission sub-band of an emitting ion, and the second band corresponds with a second emission sub-band of the same emitting ion. A processing system calculates a comparison value that represents a mathematical relationship (e.g., a ratio) between a first intensity of the emitted radiation in the first band with a second intensity of the emitted radiation in the second band, and determines whether the comparison value compares favorably with an authentication parameter. When the comparison value compares favorably with the authentication parameter, the article is identified as being authentic.

Abstract translation: 用于物品认证的方法和装置包括将物品的区域暴露于激发辐射的激发辐射发生器，以及至少两个辐射检测器，其检测来自第一频带中的区域和不与第一频带重叠的第二频带中的区域的发射辐射 带。 第一带对应于发射离子的第一发射子带，第二带对应于相同发射离子的第二发射子带。 处理系统计算表示第一频带中发射的辐射的第一强度与第二频带中发射的辐射的第二强度之间的数学关系（例如，比率）的比较值，并且确定比较值是否比较 有利于认证参数。 当比较值与验证参数相比较时，该物品被识别为真实的。

公开(公告)号：US20150241359A1

公开(公告)日：2015-08-27

申请号：US14191646

申请日：2014-02-27

Applicant: General Electric Company

Inventor： Heikki Haveri ,  Timo Merilainen

IPC: G01N21/85 ,  G01J5/02 ,  A61M16/04 ,  A61M16/00 ,  A61M16/01 ,  G01J5/10 ,  A61M16/08

CPC classification number: A61M16/085 ,  A61M16/01 ,  A61M16/021 ,  A61M16/04 ,  A61M16/0833 ,  A61M2205/3313 ,  A61M2205/3368 ,  A61M2230/432 ,  A61M2230/435 ,  A61M2230/437 ,  G01J3/0286 ,  G01J3/28 ,  G01J3/42 ,  G01J3/427 ,  G01J5/027 ,  G01J5/10 ,  G01J5/20 ,  G01J2005/106 ,  G01N21/274 ,  G01N21/314 ,  G01N21/3504 ,  G01N33/497 ,  G01N2021/8578

Abstract: A method for determining a chance to enable a zeroing of gas analysis is disclosed herein. The method includes emitting radiation, and receiving emitted radiation, the received radiation comprising a first wavelength range absorbed by the at least one desired gas component and one or more disturbing factor, and a second wavelength range absorbed by the disturbing factor, the first wavelength range differing from the second wavelength range. The method also includes providing to a processing unit a first signal data indicative of a concentration of the at least one desired gas component and absorption of the disturbing factor, and a second signal data indicative of absorption of the disturbing factor. The method also includes determining a stability of the first and second signal data as a function of time, and if they are substantially stable enabling the zeroing to improve a measurement accuracy.

Abstract translation: 本文公开了一种用于确定能够使气体分析归零的机会的方法。 该方法包括发射辐射和接收发射的辐射，所接收的辐射包括由至少一个所需气体成分吸收的第一波长范围和一个或多个干扰因子以及由干扰因子吸收的第二波长范围，第一波长范围 与第二波长范围不同。 该方法还包括向处理单元提供指示所述至少一个所需气体组分的浓度和干扰因子的吸收的第一信号数据以及指示干扰因子吸收的第二信号数据。 该方法还包括确定作为时间的函数的第一和第二信号数据的稳定性，以及如果它们基本上是稳定的，使得归零能够提高测量精度。

公开(公告)号：US20150226666A1

公开(公告)日：2015-08-13

申请号：US14424850

申请日：2013-08-06

Applicant: NewSouth Innovations Pty Limited

Inventor： Charles Charbel Harb

IPC: G01N21/39 ,  G01J3/42

CPC classification number: G01N21/39 ,  G01J3/021 ,  G01J3/10 ,  G01J3/42 ,  G01J3/427 ,  G01J3/433 ,  G01J2003/102 ,  G01N21/031 ,  G01N21/3504 ,  G01N2201/06113 ,  H01S3/08063 ,  H01S3/105

Abstract: Methods and optical detection systems (200, 300, 800, 900) for generating and processing a real-time time-domain cavity ringdown spectroscopy (CRDS) signal (831, 931) from an absorbing species in an optical detection system (200, 300, 800, 900) having an optical ringdown cavity (200, 300) are disclosed. The optical ringdown cavity (200, 300) is adapted for accepting a sample of an absorbing species. One or more modulated light signals (241,243,245,341) are generated using one or more light sources (240, 242, 244, 340). The light source(s) (240, 242, 244, 340) is pulsed at a specified pulse rate(s). The modulated light signal(s) (241,243,245, 341) is resonated using the optical ringdown cavity (200, 300) comprising a plurality of mirrors (220, 230), or sets of mirrors (320, 330), to produce the CRDS signal (831, 931). The reflectivity of the mirrors (220, 230), or sets of mirrors (320, 330), is dependent upon the pulse rate of the modulated light signals (241,243,245,341). Different beamlines (212, 214, 216, 312, 314, 316) are established by the modulated light signal(s) (241,243,245, 341) and the mirrors (220, 230, 320, 330) interacting with the absorbing species sample.

Abstract translation: 用于从光学检测系统（200,300）中的吸收物质生成和处理实时时域衰减光谱（CRDS）信号（831,931）的方法和光学检测系统（200,300,800,900） ，800,900），其具有光学衰减腔（200,300）。 光学衰减腔（200,300）适于接收吸收物质的样品。 使用一个或多个光源（240,242,244,340）产生一个或多个调制光信号（241,243,245,341）。 光源（240,242,244,340）以指定的脉冲速率脉冲。 调制光信号（241,243,245,341）使用包括多个反射镜（220,230）或一组反射镜（320,330）的光学环形空腔（200,300）进行谐振，以产生CRDS信号 （831,931）。 反射镜（220,230）或反射镜组（320,330）的反射率取决于调制光信号的脉冲速率（241,243,245,341）。 通过调制光信号（241,243,245,341）和与吸收物质样品相互作用的反射镜（220,230,320,330）建立不同的光束线（212,214,216,312,314,316）。

公开(公告)号：US20150219906A1

公开(公告)日：2015-08-06

申请号：US14427437

申请日：2013-09-12

Applicant: FORSCHUNGSVERBUND BERLIN E.V.

Inventor： Martin Maiwald ,  Bernd Sumpf

IPC: G02B27/10 ,  G02B27/09

CPC classification number: G02B27/1006 ,  G01J3/427 ,  G01J3/44 ,  G01J2003/4424 ,  G01N21/65 ,  G01N2021/399 ,  G01N2201/0221 ,  G01N2201/024 ,  G02B27/09 ,  G02B27/1086 ,  G02B27/141

Abstract: The invention relates to a device (122) having an arrangement of optical elements comprising excitation light sources (101, 115) for generating individual light beams (102, 116) having different wavelengths for exciting a sample in such a way that light scattered back from the sample as a result of the excitation is made available to a Raman spectroscopic analysis. The device (122) comprises deflection devices (103, 117) associated with the individual light beams (102, 116) for deflecting the individual light beams (102, 116) onto a common light path, wherein the common light path comprises a same optical system (109) for focusing the light beams (102, 116).

Abstract translation: 本发明涉及一种具有光学元件布置的装置（122），该装置包括用于产生具有不同波长的单个光束（102,116）的激发光源（102,116），用于激发样品，使得从 作为激发结果的样品可用于拉曼光谱分析。 装置（122）包括与单个光束（102,116）相关联的偏转装置（103,117），用于将各个光束（102,116）偏转到公共光路上，其中，公共光路包括相同的光 系统（109），用于聚焦光束（102,116）。

公开(公告)号：US08829440B2

公开(公告)日：2014-09-09

申请号：US13831438

申请日：2013-03-14

Applicant: Ronald T. Logan, Jr. ,  Joseph R. Demers

Inventor： Ronald T. Logan, Jr. ,  Joseph R. Demers

IPC: G01N21/35 ,  A61B5/05

CPC classification number: G01J3/427 ,  A61B5/0507 ,  G01J3/10 ,  G01J3/42 ,  G01J3/4531 ,  G01N21/3581 ,  G01N21/3586 ,  G01N21/39

Abstract: An apparatus for analyzing, identifying or imaging an target including first and second laser beams coupled to a pair of photoconductive switches to produce CW signals in one or more bands in a range of frequencies greater than 100 GHz focused on and transmitted through or reflected from the target; and a detector for acquiring spectral information from signals received from the target and using a multi-spectral heterodyne process to generate an electrical signal representative of some characteristics of the target. The lasers are tuned to different frequencies and a frequency shifter in the path of one laser beam allows the terahertz beam to be finely adjusted in one or more selected frequency bands.

Abstract translation: 一种用于分析，识别或成像目标的装置，包括耦合到一对光电导开关的第一和第二激光束，以在大于100GHz的频率的范围内的一个或多个频带中产生CW信号，该信号集中于并经由 目标; 以及检测器，用于从从目标接收的信号中获取光谱信息，并使用多光谱外差处理产生表示目标的某些特性的电信号。 将激光器调谐到不同的频率，并且在一个激光束的路径中的频移器允许在一个或多个所选频带中微调太赫兹波束。

公开(公告)号：US20140070077A1

公开(公告)日：2014-03-13

申请号：US14083904

申请日：2013-11-19

Applicant: MURATA MANUFACTURING CO., LTD.

Inventor： HIROFUMI TSUCHIMOTO ,  Toru Shimuta

IPC: G01J1/44

CPC classification number: G01J1/44 ,  A61B5/02433 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/7203 ,  G01J3/427 ,  G01J2001/444 ,  G01N21/256 ,  G01N21/3151

Abstract: An optical sensor device includes a light emitter for emitting, to a living body, lights having two wavelengths and blinking at a predetermined frequency, and a light receiver for receiving the lights from the living body. The light receiver outputs first and second detection signals corresponding to the respective wavelengths. A filter circuit extracts, from the first and second detection signals, modulation signals that are obtained with amplitude modulation of signals of the predetermined frequency. The modulation signals are amplified by a post-amplifier and are taken into an arithmetic processing unit after being converted to digital signals by an AD converter. The arithmetic processing unit calculates DC components and AC components of the first and second detection signals by employing the modulation signals converted the digital signals.

Abstract translation: 光传感器装置包括：发光体，用于向生物体发射具有两个波长并以预定频率闪烁的光;以及光接收器，用于从生物体接收光。 光接收器输出对应于各个波长的第一和第二检测信号。 滤波器电路从第一和第二检测信号中提取通过预定频率的信号的幅度调制获得的调制信号。 调制信号由后置放大器放大，并通过AD转换器转换成数字信号后被送入运算处理单元。 算术处理单元通过采用转换数字信号的调制信号来计算第一和第二检测信号的直流分量和交流分量。