Abstract:
The invention relates to a coating arrangement for coating particles, a method for coating particles, and corresponding uses. The coating arrangement includes a coating chamber and a coating device arranged in the coating chamber. This device comprises a hollow body with an axis, the inner wall of which forms a particle track around the axis of the hollow body, a particle source and a particle sink, and at least one coating source. The coating source is adapted for emitting a coating material along a direction perpendicular to the axis of the hollow body. Furthermore, the coating device comprises a rotation device which is adapted for rotating the hollow body about its axis, and a cleaning device which is arranged in the interior of the hollow body in a stationary manner with respect to the hollow body and is adapted for removing adhering coating material from the inner wall of the hollow body.
Abstract:
A method of treating a tubular medical device with a biomolecule comprises the steps of: a) providing a polyolefin tubular substrate forming a tubular medical device; b) cleaning the tubular polyolefin substrate; c) exposing the tubular polyolefin substrate to a reactive gas containing at least one of acrylic acid and siloxane and to plasma energy to yield a plasma-deposited coating on at least one surface of the tubular polyolefin substrate; and d) attaching a biomolecule to the polyolefin substrate following formation of the plasma-deposited coating on at least one surface of the tubular polyolefin substrate, and wherein the biomolecule is at least one of an antibacterial agent, antimicrobial agent, anticoagulant, heparin, antithrombotic agent, platelet agent, anti-inflammatory, enzyme, catalyst, hormone, growth factor, drug, vitamin, antibody, antigen, protein, nucleic acid, dye, a DNA segment, an RNA segment, protein, and peptide.
Abstract:
A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
Abstract:
A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a hydrogel surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
Abstract:
An implantable device includes an exterior gold surface and a thin film disposed on the exterior gold surface and forming a barrier between the exterior gold surface and an implanted environment, in which the thin film includes molecules with a head portion, the head portion attached to the exterior gold surface.
Abstract:
A method of forming a lubricating coating on a razor blade that includes: providing a razor blade having a body and a cutting edge tapering from the body; providing a tank of a colloidal dispersion of a polymer having less than 2% in weight of polymer particles; providing a spray gun in fluid communication with the tank, the gun having an end directed to a blade-spraying region; placing the razor blade at a predetermined temperature (T) in the blade-spraying region; flowing the colloidal dispersion from the tank to the end of the spray gun, and in a direction to the razor blade; controlling a first gas stream to nebulise the colloidal dispersion into a mist in a dispersion region located between the end of the spray gun and the razor blade; independently controlling a second gas stream to control the mist properties; transporting the mist from the dispersion region to the razor blade placed in the blade-spraying region, the razor blade being at the predetermined temperature (T) so that water evaporates from the mist, and sintering the polymer.
Abstract:
The invention provides a method of coating a surface with a water and oil repellant polymer layer. The method comprises the steps of providing a substrate with a surface, exposing the surface to a monomer compound, and exposing the surface to a continuous plasma having a plasma power provided by a plasma circuit. During the exposition of the surface to the continuous plasma, the plasma power is reduced from an initial higher plasma power to a final lower plasma power, the final lower plasma power being less than 35% of the initial higher plasma power, thus applying an even polymer layer exhibiting a water contact angle of more than 110°.
Abstract:
A manufacturing process for forming and spray coating formed objects, such as pharmaceutical tablets, by spray coating during a dedusting process carried out after forming. The process optionally includes a drying step, which may be carried out using an infrared emitter.
Abstract:
A continuous dosage form coating apparatus uses vibrational impulses to maintain a dosage forms in a fluid state to expose them to a coating material atomized by spraying.
Abstract:
The present invention relates to a method for masking the inner surface of a tubular medical device with a fluid in order to selectively coat the outer surface of the tubular medical device. The inner lumen of the tubular medical device is filled with the fluid prior to deposition of a coating to the outer surface.