-
公开(公告)号：SK10582001A3
公开(公告)日：2001-12-03
申请号：SK10582001
申请日：2000-01-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAI YUJIA , DAVIDSEN STEVEN K , HEYMAN HOWARD R , HOLMES JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H
IPC: A61K31/341 , A61K31/357 , A61K31/40 , A61K31/421 , A61P1/02 , A61P1/04 , A61P17/02 , A61P19/02 , A61P19/10 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D207/09 , C07D207/14 , C07D207/48 , C07D263/04 , C07D307/14 , C07D317/28 , A61K31/335
Abstract: Compounds having the formula are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
-
公开(公告)号：HU0002037A2
公开(公告)日：2001-05-28
申请号：HU0002037
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F JR , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
-
公开(公告)号：CZ473099A3
公开(公告)日：2000-06-14
申请号：CZ473099
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F JR , FLORJANIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN ROBIN H , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: A61K31/16 , A61P19/02 , A61P35/00 , C07C259/00 , C07C259/04
-
公开(公告)号：SK170599A3
公开(公告)日：2000-05-16
申请号：SK170599
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F JR , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07C259/00
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
-
公开(公告)号：AU8513998A
公开(公告)日：1999-02-22
申请号：AU8513998
申请日：1998-07-27
Applicant: ABBOTT LAB
Inventor： CURTIN MICHAEL L , DAVIDSEN STEVEN K , DELLARIA JOSEPH F , FLORJANCIC ALAN S , GIESLER JAMIE , GONG JIANCHUN , GUO YAN , HEYMAN H ROBIN , HOLMS JAMES H , MICHAELIDES MICHAEL R , STEINMAN DOUGLAS H , WADA CAROL K , XU LIANHONG
IPC: C07D233/74 , A61K31/275 , A61K31/351 , A61K31/352 , A61K31/4035 , A61K31/4166 , A61K31/4178 , A61K31/421 , A61K31/428 , A61K31/4439 , A61K31/4465 , A61K31/45 , A61K31/454 , A61K31/50 , A61P1/02 , A61P1/04 , A61P19/02 , A61P19/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07C259/06 , C07C311/05 , C07C311/18 , C07C317/28 , C07C317/40 , C07C323/47 , C07C323/62 , C07D207/40 , C07D207/404 , C07D207/416 , C07D209/48 , C07D211/88 , C07D213/68 , C07D233/76 , C07D233/78 , C07D237/14 , C07D263/44 , C07D275/04 , C07D275/06 , C07D309/14 , C07D311/18 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07C259/00
Abstract: Compounds having formula (I) are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
-
Patent Agency Ranking
公开(公告)号：AU1303695A
公开(公告)日：1995-07-03
申请号：AU1303695
申请日：1994-12-08
Applicant: ABBOTT LAB
Inventor： SUMMERS JAMES B JR , DAVIDSEN STEVEN K , CURTIN MICHAEL L , HEYMAN H ROBIN , SHEPPARD GEORGE S , XU LIANHONG , CARRERA GEORGE M JR , GARLAND ROBERT B
IPC: C07D487/04 , A61K31/41 , A61K31/425 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/505 , A61P7/02 , A61P11/00 , A61P11/16 , A61P17/00 , A61P29/00 , A61P37/08 , C07D401/12 , C07D403/10 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , A61K31/50
Abstract: The present invention relates to compounds of formula and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
-
公开(公告)号：UA103351C2
公开(公告)日：2013-10-10
申请号：UAA201108416
申请日：2009-12-04
Applicant: ABBOTT LAB
Inventor： MICHAELIDES MICHAEL R , CURTIN MICHAEL L , FREY ROBIN R
IPC: C07D495/04 , A61K31/4365 , A61P35/00
Abstract: Описанісполуки, якіінгібуютьпротеїнкінази, такіяк Aurоrа-кіназиі сімействакіназ VEGFR і PDGFR, зполіпшенимпрофілембезпекичерезнизькеінгібування CYP3A4, композиції, щомістятьсполуки, іспособилікуваннязахворюваньз використаннямсполук.
-
公开(公告)号：UY33726A
公开(公告)日：2012-06-29
申请号：UY33726
申请日：2011-11-11
Applicant: ABBOTT LAB
Inventor： WOLLER KEVIN R , HELMUT MACK , CURTIN MICHAEL L , SORENSEN BRYAN K , HEYMAN HOWARD R , CLARK RICK F , SHAH OMAR J , MICHAEL MICHAELIDES , CHRIS TSE , ANIL VASUDEVAN , HANSEN TODD M , RAMZI SWEIS , PLIUSHCHEV MARINA A
IPC: A61K31/341 , A61K31/357 , A61K31/381 , A61K31/4015 , A61K31/4025 , A61K31/4035 , A61K31/4155 , A61K31/416 , A61K31/427 , A61K31/4355 , A61K31/438 , A61K31/444 , A61K31/496 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K31/55 , C07D205/12 , C07D209/44 , C07D223/10 , C07D231/02 , C07D231/56 , C07D237/02 , C07D239/02 , C07D241/02 , C07D265/32 , C07D277/02 , C07D295/033 , C07D307/02 , C07D317/10 , C07D319/16 , C07D333/48 , C07D401/14 , C07D403/02 , C07D403/14 , C07D405/02 , C07D471/04 , C07D471/10 , C07D491/048 , C07D491/113
Abstract: Compuestos que inhiben la actividad de la NAMPT, composiciones que contienen los compuestos y métodos para tratar enfermedades en las cuales se expresa la NAMPT. Compuestos que inhiben la actividad de la ROCK, composiciones que contienen los compuestos y métodos para tratar enfermedades en las cuales se expresa la ROCK.
-
公开(公告)号：DK1648905T3
公开(公告)日：2009-03-30
申请号：DK04779180
申请日：2004-07-26
Applicant: ABBOTT LAB
Inventor： BETSCHMANN PATRICK , BURCHAT ANDREW F , CALDERWOOD DAVID J , CURTIN MICHAEL L , DAVIDSEN STEVEN K , DAVIS HEATHER M , FREY ROBIN R , HEYMAN HOWARD R , HIRST GAVIN C , HRNCIAR PETER , MICHAELIDES MICHAEL R , MUCKEY MELANIE A , RAFFERTY PAUL , WADA CAROL K
IPC: C07D495/04 , A61K31/4355 , A61K31/4365 , A61P35/00 , C07D491/04 , C07D498/04
Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
-
公开(公告)号：CA2631664A1
公开(公告)日：2007-06-14
申请号：CA2631664
申请日：2006-12-08
Applicant: ABBOTT LAB
Inventor： DAI YUJIA , STEINMAN DOUGLAS H , CURTIN MICHAEL L , FREY ROBIN R , MCCLELLAN WILLIAM J , MICHAELIDES MICHAEL R , HOLMS JAMES H
IPC: C07D487/04 , A61K31/519 , A61P35/00 , C07D495/04
Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating cancer using the compounds are disclosed.
-
-
-
-
-
-
-
-
-
Search Results
97
records
(took 0.023 seconds)
