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公开(公告)号：HK1104558A1
公开(公告)日：2008-01-18
申请号：HK07109677
申请日：2007-09-05
Applicant: ABBOTT LAB
Inventor： DEGOEY DAVID A , FLOSI WILLIAM J , GRAMPOVNIK DAVID J , KLEIN LARRY L , KEMPF DALE J , WANG XIU C
IPC: A61K20060101 , A61P20060101 , C07F20060101
Abstract: A compound of the formula I, II or III is disclosed as a prodrug of an HIV protease inhibitor. Methods and compositions of inhibiting HIV protease activity and treating HIV infection are also disclosed.
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公开(公告)号：HK1100659A1
公开(公告)日：2007-09-28
申请号：HK07102279
申请日：2007-02-28
Applicant: ABBOTT LAB
Inventor： DEGOEY DAVID A , FLENTGE CHARLES A , FLOSI WILLIAM J , GRAMPOVNIK DAVID J , KEMPF DALE J , KLEIN LARRY L , YEUNG MING C , RANDOLPH JOHN T , WANG XIU C , YU SU
IPC: A61K20060101 , A61P20060101 , C07D20060101 , C07D213/30 , C07D213/40 , C07D401/06 , C07D401/12 , C07D401/14 , C07D417/06 , C07D417/14 , C07D471/04 , C07D493/04
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公开(公告)号：AU2005270124A1
公开(公告)日：2006-02-09
申请号：AU2005270124
申请日：2005-06-29
Applicant: ABBOTT LAB
Inventor： FLOSI WILLIAM J , KLEIN LARRY L , WANG XIU C , GRAMPOVNIK DAVID J , DEGOEY DAVID A , KEMPF DALE J
IPC: C07F9/00 , A61K31/661 , A61P35/00 , C07F9/09
Abstract: A compound of the formula I, II or III is disclosed as a prodrug of an HIV protease inhibitor. Methods and compositions of inhibiting HIV protease activity and treating HIV infection are also disclosed.
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公开(公告)号：CA2549228A1
公开(公告)日：2005-07-07
申请号：CA2549228
申请日：2004-11-10
Applicant: ABBOTT LAB
Inventor： CHEN HUI-JU , RANDOLPH JOHN T , YEUNG MING C , DEGOEY DAVID A , KLEIN LARRY L , GRAMPOVNIK DAVID J , FLENTGE CHARLES A , FLOSI WILLIAM J , KEMPF DALE J , HUTCHINSON DOUGLAS K , HUANG PEGGY P
IPC: C07D401/14 , A61K31/4166 , A61K31/4178 , A61P31/18 , C07C243/24 , C07C271/22 , C07D401/06 , C07D403/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/06 , C07D417/14
Abstract: A compound of the formula (I) is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
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公开(公告)号：PL343678A1
公开(公告)日：2001-08-27
申请号：PL34367899
申请日：1999-04-12
Applicant: ABBOTT LAB
Inventor： MARING CLARENCE J , GU YU-GUI , CHEN HUI-JU , CHEN YUANWEI , DEGOEY DAVID A , FLOSI WILLIAM J , GIRANDA VINCENT L , GRAMPOVNIK DAVID J , KATI WARREN M , KEMPF DALE J , KLEIN LARRY L , KRUEGER ALLAN C , LIN ZHEN , MADIGAN DAROLD L , MCDANIEL KEITH F , MUCHMORE STEVEN W , SHAM HING L , STEWART KENT D , STOLL VINCENT S , SUN MINGHUA , WANG GARY T , WANG SHELDON , XU YIBO , YEUNG MING C , ZHAO CHEN , KENNEDY APRIL
IPC: A61K31/401 , A61K31/4025 , A61K31/41 , A61K31/4155 , A61K31/4178 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/5377 , A61P31/16 , A61P43/00 , C07D207/16 , C07D207/32 , C07D207/325 , C07D207/327 , C07D401/12 , C07D403/04 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/06 , C07D521/00 , C07F9/572 , A61K31/40 , C07D407/04
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Patent Agency Ranking
公开(公告)号：BG104962A
公开(公告)日：2001-07-31
申请号：BG10496200
申请日：2000-11-17
Applicant: ABBOTT LAB
Inventor： MARING CLARENCE J , GU YU-GUI , CHEN HUI-JU , CHEN YCANWEI , DEGOEY DAVID A , FLOSI WILLIAM J , GIRANDA VINCENT L , GRAMPOVNIK DAVID J , KATI WARREN M , KEMPF DALE J , KLEIN LARRY L , KRUEGER ALLAN C , LIN ZHEN , MADIGAN DAROLD L , MCDANIEL KEITH F , MUCHMORE STEVEN W , SHAM HING L , STEWART KENT D , STOLL VINCENT S , SUN MINGHUA , WANG GARY T , WANG SHELDON , XU YIBO , YEUNG MING C , ZHAO CHEN , KENNEDY APRIL
IPC: A61K31/401 , A61K31/4025 , A61K31/41 , A61K31/4155 , A61K31/4178 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/5377 , A61P31/16 , A61P43/00 , C07D207/16 , C07D207/32 , C07D207/325 , C07D207/327 , C07D401/12 , C07D403/04 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/06 , C07D521/00 , C07F9/572 , A61K31/40 , C07D407/04
Abstract: Disclosed are compounds of formula which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminodase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes. 56 claims
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公开(公告)号：AU7831200A
公开(公告)日：2001-04-30
申请号：AU7831200
申请日：2000-09-22
Applicant: ABBOTT LAB
Inventor： MARING CLARENCE J , DEGOEY DAVID A , FLOSI WILLIAM J , GIRANDA VINCENT L , KEMPF DALE J , KENNEDY APRIL , KLEIN LARRY L , KRUEGER ALLAN C , MCDANIEL KEITH F , STOLL VINCENT S , SUN MINGHUA , ZHAO CHEN
IPC: A61P31/00 , C07D471/04 , C07D487/04 , C07D498/04 , A61K31/4353 , A61K31/5383 , C07D209/00 , C07D221/00 , C07D265/00
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公开(公告)号：CA2329422A1
公开(公告)日：1999-10-28
申请号：CA2329422
申请日：1999-04-12
Applicant: ABBOTT LAB
Inventor： MADIGAN DAROLD L , LIN ZHEN , KRUEGER ALLAN C , MARING CLARENCE J , DEGOEY DAVID A , XU YIBO , YEUNG MING C , FLOSI WILLIAM J , ZHAO CHEN , KENNEDY APRIL , MUCHMORE STEVEN W , STEWART KENT D , KEMPF DALE J , SHAM HING L , GRAMPOVNIK DAVID J , STOLL VINCENT S , KATI WARREN M , WANG GARY T , GU YU-GUI , SUN MINGHUA , WANG SHELDON , MCDANIEL KEITH F , GIRANDA VINCENT L , KLEIN LARRY L , CHEN YUANWEI , CHEN HUI-JU
IPC: A61K31/401 , A61K31/4025 , A61K31/41 , A61K31/4155 , A61K31/4178 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/5377 , A61P31/16 , A61P43/00 , C07D207/16 , C07D207/32 , C07D207/325 , C07D207/327 , C07D401/12 , C07D403/04 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/06 , C07D521/00 , C07F9/572 , A61K31/40 , C07D407/04
Abstract: Disclosed are compounds of formula (I) which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.
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公开(公告)号：BRPI0816994A2
公开(公告)日：2015-03-24
申请号：BRPI0816994
申请日：2008-09-17
Applicant: ABBOTT LAB
Inventor： ROLF WAGNER , TUFANO MICHAEL D , STEWART KENT D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , CHEN SHUANG , FRANCZYK THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , ZHANG GEOFF G Z
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10 , C07D417/10
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公开(公告)号：CA2737601C
公开(公告)日：2014-10-21
申请号：CA2737601
申请日：2010-06-10
Applicant: ABBOTT LAB
Inventor： DEGOEY DAVID A , KATI WARREN M , HUTCHINS CHARLES W , DONNER PAMELA L , KRUEGER ALLAN C , RANDOLPH JOHN T , MOTTER CHRISTOPHER E , NELSON LISSA T , PATEL SACHIN V , MATULENKO MARK A , KEDDY RYAN G , JINKERSON TAMMIE K , HUTCHINSON DOUGLAS K , FLENTGE CHARLES A , WAGNER ROLF , MARING CLARENCE J , TUFANO MICHAEL D , BETEBENNER DAVID A , ROCKWAY TODD W , LIU DACHUN , PRATT JOHN K , SARRIS KATHY , WOLLER KEVIN R , WAGAW SEBLE H , CALIFANO JEAN C , LI WENKE , CASPI DANIEL D , BELLIZZI MARY E , GAO YI
IPC: C07D403/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14 , C07D401/14 , C07D417/14 , C07K5/062 , C07K5/065
Abstract: Compounds for Formula I effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection. (see formula I)
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