公开(公告)号：KR1020140127679A

公开(公告)日：2014-11-04

申请号：KR1020130046343

申请日：2013-04-25

Applicant: 한국화학연구원

Inventor： 박보근 ,  김창균 ,  정택모 ,  전동주 ,  여소정 ,  정윤장 ,  공기정

IPC: C23C16/06 ,  C23C16/448

Abstract: 본 발명은 하기 화학식 1로 표시되는 납 전구체에 관한 것으로, 상기 납 전구체는 황을 포함하고 있는 전구체로서 열적 안정성과 휘발성이 개선되고 박막 제조 중에 별도의 황을 첨가시키지 않아도 되는 장점을 가지기 때문에 이를 이용하여 쉽게 양질의 황화납 박막을 제조할 수 있다.
[화학식 1]

(상기 식에서, R
1 , R
2 는 각각 독립적으로 C1-C10의 선형 또는 분지형 알킬기이고, R
3 , R
4 는 각각 독립적으로 C1-C10의 선형 또는 분지형의 알킬기 또는 C1-C10의 선형 또는 분지형의 플루오로알킬기이고, n은 1 내지 3 범위의 정수에서 선택된다.)

Abstract translation: 本发明涉及由下式1表示的铅前体。所述前体包括硫，具有改善的热稳定性和挥发性，在制备薄膜期间不需要加入单独的硫，从而容易地制造高质量的铅 硫化物薄膜。 [式1]（式1中，R 1和R 2各自独立地表示C1-C10的直链或支链烷基，R2和R3各自独立地表示C1-C10的直链或支链烷基或C1的直链或支链的三氟烷基 -C10，N选自1〜3的整数。）。

公开(公告)号：KR1020140068719A

公开(公告)日：2014-06-09

申请号：KR1020120136558

申请日：2012-11-28

Applicant: 한국화학연구원

Inventor： 박보근 ,  정택모 ,  김창균 ,  전동주 ,  정은애 ,  정석종

IPC: C07F15/00 ,  C07B61/00

CPC classification number: C07F15/0046 ,  C23C16/18

Abstract: The present invention relates to a ruthenium precursor represented by Chemical Formula 1. The ruthenium precursor has improved thermal stability and volatility and does not have to use oxygen during the deposition of a thin film so that a good quality ruthenium thin film can be produced. [Chemical Formula 1](In Formula, R1-R12 are independently H, or C1-C4 linear or branched alkyl groups.).

Abstract translation: 本发明涉及由化学式1表示的钌前体。钌前体具有改善的热稳定性和挥发性，并且在沉积薄膜期间不必使用氧气，从而可以生产出优质的钌薄膜。 [化学式1]（式中，R 1 -R 12独立地为H或C 1 -C 4直链或支链烷基）。

公开(公告)号：KR101331971B1

公开(公告)日：2013-11-25

申请号：KR1020120048230

申请日：2012-05-07

Applicant: 한국화학연구원

Inventor： 박보근 ,  김창균 ,  정택모 ,  전동주 ,  이영국 ,  박주현 ,  강성구

IPC: C07F7/22 ,  C23C16/18

Abstract: 본 발명은 하기 화학식 1로 표시되는 주석 전구체에 관한 것으로, 상기 주석 전구체는 황을 포함하고 있는 전구체로서 박막 제조 중에 별도의 황을 첨가시키지 않아도 되는 장점이 있고 열적 안정성과 휘발성이 향상되어 양질의 황화주석 박막을 형성할 수 있다.
[화학식 1]

(상기 식에서, R1, R2는 각각 독립적으로 C1-C10의 선형 또는 분지형 알킬기이고, R3, R4는 각각 독립적으로 C1-C10의 선형 또는 분지형 알킬기, 또는 C1-C10의 플루오르화 알킬기이며, n은 1 내지 3이다.)

公开(公告)号：KR101331970B1

公开(公告)日：2013-11-25

申请号：KR1020120047442

申请日：2012-05-04

Applicant: 한국화학연구원

Inventor： 박보근 ,  김창균 ,  정택모 ,  전동주 ,  이영국 ,  박주현 ,  강성구

IPC: C07F5/00 ,  B05D1/18 ,  C23C16/18

Abstract: 본 발명은 하기 화학식 1로 표시되는 인듐 전구체에 관한 것으로, 상기 인듐 전구체는 황을 포함하고 있는 전구체로서 박막 제조 중에 별도의 황을 첨가시키지 않아도 되는 장점이 있고 열적 안정성과 휘발성이 향상되어 양질의 황화인듐 박막을 형성할 수 있다.
[화학식 1]

(상기 식에서, R1, R2는 각각 독립적으로 C1-C10의 선형 또는 분지형 알킬기이고, R3, R4는 각각 독립적으로 C1-C10의 선형 또는 분지형 알킬기, 또는 C1-C10의 플루오르화 알킬기이며, X 는 Cl, Br 또는 I이고, n은 1 내지 3이다.)

公开(公告)号：KR1020130127025A

公开(公告)日：2013-11-22

申请号：KR1020120048239

申请日：2012-05-07

Applicant: 한국화학연구원

Inventor： 박보근 ,  김창균 ,  정택모 ,  전동주 ,  박주현 ,  송정인

IPC: C07F1/08 ,  C23C16/18

CPC classification number: C07F1/08 ,  C23C16/305 ,  C23C16/45553

Abstract: The present invention relates to a copper precursor represented by chemical formula 1, wherein the copper precursor includes sulfur, has no need of adding separate sulfur during manufacturing thin films, and improves thermal stability and volatility, thereby allowing high quality copper sulfide thin films. In chemical formula 1, R1 and R2 are linear or branched alkyl of C1-C10, respectively, R3 and R4 are linear or branched alkyl of C1-C10 or fluorinated alkyl of C1-C10, respectively, and n is selected from numbers 1 to 3.

Abstract translation: 本发明涉及由化学式1表示的铜前体，其中铜前体包括硫，在制造薄膜期间不需要添加单独的硫，并且提高热稳定性和挥发性，从而允许高质量的硫化铜薄膜。 在化学式1中，R1和R2分别是C1-C10的直链或支链烷基，R3和R4分别是C1-C10的直链或支链烷基或C1-C10的氟化烷基，n选自数1至 3。

公开(公告)号：KR1020130108932A

公开(公告)日：2013-10-07

申请号：KR1020120030785

申请日：2012-03-26

Applicant: 한국화학연구원

Inventor： 이선숙 ,  이일영 ,  안기석 ,  정택모 ,  이영국 ,  김창균 ,  임종선 ,  전동주 ,  박보근 ,  정석종

IPC: C01B31/02 ,  B01J8/00 ,  B01F3/12

CPC classification number: C01B32/182 ,  B01F3/1207 ,  B01J8/00 ,  B82B3/0061 ,  C01B32/23

Abstract: PURPOSE: Provided are a graphene compound wherein an amine group is introduced to easily and efficiently manufacture a graphene which is stable and well dispersed in a solvent, and a manufacturing method therefor, and a dispersion solution including the same. CONSTITUTION: A method for manufacturing a graphene compound wherein an amine group is introduced comprises the steps of: manufacturing graphene oxide having a group selected from a group consisting of an epoxy group, an OH group and a COOH group from graphite; and reacting the graphene oxide with a primary amine or a secondary amine.

Abstract translation: 目的：提供一种石墨烯化合物，其中引入胺基以容易且有效地制备稳定且良好分散在溶剂中的石墨烯及其制备方法，以及包含该石墨烯的分散溶液。 构成：其中引入胺基的石墨烯化合物的制造方法包括以下步骤：从石墨制造具有选自由环氧基，OH基和COOH基组成的组的基团的氧化石墨; 并使氧化石墨烯与伯胺或仲胺反应。

公开(公告)号：KR1020090005842A

公开(公告)日：2009-01-14

申请号：KR1020070069210

申请日：2007-07-10

Applicant: 한국화학연구원

Inventor： 전동주 ,  노재성 ,  송종환 ,  이계형 ,  김익연 ,  김순기 ,  강남숙 ,  천혜경 ,  조영식 ,  송진숙 ,  민용기 ,  김성환

IPC: C07D231/04 ,  A61K31/415 ,  A61P19/04

Abstract: A novel carbonitrile compound or its pharmaceutically acceptable salt, a method for preparing the compound, and a pharmaceutical composition containing compound are provided to prevent and treat osteoarthritis and various cancer without side effect. A carbonitrile compound is represented by the formula 1, wherein n is 1 or 2; R1 is H, halogen-substituted or unsubstituted linear or branched saturated or unsaturated C1-C10 alkyl, C3-C7 cycloalkyl, C1-C10 alkoxy, C1-C10 alkylthio, hydroxy-C1-C10 alkyl, C1-C10 alkylcarbonyl, C1-C10 alkylthio-C1-C10 alkyl, C3-C7 cycloalkyl-C1-C10 alkyl, C3-C7 cycloalkyl-C1-C10 alkyl, C1-C10 alkoxy-C1-C10 alkyl, phenyl, ar-C1-C10 alkyl, or ar-C1-C10 alkoxy group; and R2 linear or branched saturated or unsaturated C1-C10 alkyl, C3-C7 cycloalkyl, C3-C7 cycloalkyl-C1-C10 alkyl, phenyl, ar-C1-C10 alkyl, C1-C10 alkoxycarbonyl, or ar-C1-C10 alkoxycarbonyl group.

Abstract translation: 提供新的腈化合物或其药学上可接受的盐，制备该化合物的方法和含有药物组合物的化合物以预防和治疗骨关节炎和各种癌症而没有副作用。 腈化合物由式1表示，其中n为1或2; R1是H，卤素取代或未取代的直链或支链饱和或不饱和C 1 -C 10烷基，C 3 -C 7环烷基，C 1 -C 10烷氧基，C 1 -C 10烷硫基，羟基-C 1 -C 10烷基，C 1 -C 10烷基羰基，C 1 -C 10 烷硫基-C 1 -C 10烷基，C 3 -C 7环烷基-C 1 -C 10烷基，C 3 -C 7环烷基-C 1 -C 10烷基，C 1 -C 10烷氧基-C 1 -C 10烷基，苯基，芳基-C 1 -C 10烷基或芳烷基 -C 10烷氧基 和R 2直链或支链饱和或不饱和的C 1 -C 10烷基，C 3 -C 7环烷基，C 3 -C 7环烷基-C 1 -C 10烷基，苯基，芳基-C 1 -C 10烷基，C 1 -C 10烷氧基羰基或芳基-C 1 -C 10烷氧基羰基 。

公开(公告)号：KR100877394B1

公开(公告)日：2009-01-07

申请号：KR1020070069467

申请日：2007-07-11

Applicant: 한국화학연구원

Inventor： 이계형 ,  전동주 ,  김익연 ,  송종환

IPC: A61K31/415 ,  A61P19/10

CPC classification number: A61K31/415 ,  A61K31/121 ,  A61K31/50

Abstract: A pharmaceutical composition for treating and preventing osteoporosis is provided to improve the selectivity and inhibitory activity to cathepsin K. A pharmaceutical composition for treating and preventing osteoporosis comprises a carbonitrile compound represented by the formula 1, wherein n is 1 or 2; R1 is H, F-substituted or unsubstituted linear or branched saturated or unsaturated C1-C10 alkyl, C3-C7 cycloalkyl, C1-C10 alkoxy, C1-C10 alkylthio, C1-C10 hydroxyalkyl, C1-C10 alkylcarbonyl, C1-C10 alkylthio C1-C10 alkyl, C3-C7 cycloalkyl C1-C10 alkyl, C3-C7 cycloalkyl C1-C10 alkoxy, C1-C10 alkoxy C1-C10 alkyl, phenyl, ar-C1-C10 alkyl, or ar-C1-C10 alkoxy group; and R2 is linear or branched saturated or unsaturated C1-C10 alkyl, C3-C7 cycloalkyl, C3-C7 cycloalkyl C1-C10 alkyl, phenyl, ar-C1-C10 alkyl, C1-C10 alkoxycarbonyl, or ar-C1-C10 alkoxy group.

Abstract translation: 提供了用于治疗和预防骨质疏松症的药物组合物，以提高对组织蛋白酶K的选择性和抑制活性。用于治疗和预防骨质疏松症的药物组合物包括由式1表示的腈化合物，其中n为1或2; R1是H，F-取代或未取代的直链或支链饱和或不饱和的C1-C10烷基，C3-C7环烷基，C1-C10烷氧基，C1-C10烷硫基，C1-C10羟基烷基，C1-C10烷基羰基，C1-C10烷硫基C1 -C 10烷基，C 3 -C 7环烷基C 1 -C 10烷基，C 3 -C 7环烷基C 1 -C 10烷氧基，C 1 -C 10烷氧基C 1 -C 10烷基，苯基，芳基-C 1 -C 10烷基或芳烷基-C 1 -C 10烷氧基; 并且R 2是直链或支链饱和或不饱和的C 1 -C 10烷基，C 3 -C 7环烷基，C 3 -C 7环烷基C 1 -C 10烷基，苯基，芳基-C 1 -C 10烷基，C 1 -C 10烷氧基羰基或芳烷基-C 1 -C 10烷氧基 。

公开(公告)号：KR100844131B1

公开(公告)日：2008-07-04

申请号：KR1020070000624

申请日：2007-01-03

Applicant: 한국화학연구원

Inventor： 전동주 ,  김형래 ,  김광록 ,  천혜경 ,  서민정

IPC: C07D409/06 ,  C07D409/14

Abstract: A rhodanine-based compound or a pharmaceutically acceptable salt thereof is provided to show excellent inhibitory activity on CDC25B phosphatase acting on cell cycle decisively, thereby showing high anticancer activity on cancer cells. A rhodanine-based compound is represented by a formula(1), wherein each Ar1 and Ar2 is independently phenyl or pyridine, which may be substituted by at least two substituents selected from the group consisting of C1-4 alkyl, halogen, C1-7 alkoxy, C3-4 alkenyloxy, C2-4 acyl, cyano or nitro. An anti-cancer agent composition comprises the rhodanine-based compound or a pharmaceutically acceptable salt thereof as an effective ingredient.

Abstract translation: 提供了一种绕丹宁类化合物或其药学上可接受的盐，对于对细胞周期起决定性作用的CDC25B磷酸酶具有优异的抑制活性，从而对癌细胞表现出高的抗癌活性。 绕丹宁类化合物由式（1）表示，其中每个Ar 1和Ar 2独立地是苯基或吡啶，其可以被至少两个选自C 1-4烷基，卤素，C 1-7的取代基取代 烷氧基，C3-4链烯氧基，C2-4酰基，氰基或硝基。 抗癌剂组合物含有绕丹宁类化合物或其药学上可接受的盐作为有效成分。

公开(公告)号：KR100833799B1

公开(公告)日：2008-05-30

申请号：KR1020070002725

申请日：2007-01-10

Applicant: 한국화학연구원

Inventor： 전동주 ,  노재성 ,  송종환 ,  이계형 ,  김익연 ,  박창민 ,  소원영 ,  이지선 ,  김은주 ,  강남숙 ,  천혜경 ,  조영식 ,  송진숙 ,  배명애 ,  김지현 ,  조중명 ,  노성구 ,  현영란 ,  이철순 ,  이재일 ,  유성은

IPC: C07D401/06 ,  C07D413/14

Abstract: 1-[1-(3,4-Dialkoxyaryl)-pyridylmethyl]-1H-pyrazole compounds are provided to inhibit activity of PDE-4(phosphodiesterase-4) with high activity and selectivity without side effects, so that the compounds are useful for treating inflammation diseases, neurodegenerative disease and cancers. 1-[1-(3,4-Dialkoxyaryl)-pyridylmethyl]-1H-pyrazole compounds represented by the formula(1) are provided, wherein A is N or CH; R1 is linear or branched, saturated or unsaturated (C1-C7)alkyl or halogen-substituted linear or branched, saturated or unsaturated (C1-C7)alkyl; R2 is hydrogen atom, (C3-C7)cycloalkyl or (C3-C8)cycloalkylmethyl; R3, R4 and R5 are each independently hydrogen atom, phenyl, pyridinyl, N-oxypyridinyl, linear or branched, saturated or unsaturated (C1-C7)alkyl, (C3-C7)cycloalkyl, (C3-C10)cycloalkyl(C1-C7)alkyl, halogen atom, cyano, nitro, amino, mono- or di(C1-C7)alkylamino, mono- or di(C1-C7)alkylaminocarbonyl, (C3-C7)cycloalkylamino, 3- to 7-membered saturated or unsaturated hetero ring containing oxygen, nitrogen or sulfur in hetero ring, guanidinyl, ureido, benzyl, benzyloxy, formyl, (C1-C7)alkanoyl, (C1-C7)alkoxy, (C1-C7)alkoxy(C1-C7)alkyl, hydroxy(C1-C7)alkyl, carboxyl or (C1-C7)alkoxycarbonyl; and R6 is pyridinyl or N-oxypyridinyl group.

Abstract translation: 提供1- [1-（3,4-二烷氧基芳基） - 吡啶基甲基] -1H-吡唑化合物以抑制具有高活性和选择性的PDE-4（磷酸二酯酶-4）的活性而没有副作用，使得该化合物可用于 治疗炎症疾病，神经退行性疾病和癌症。 提供由式（1）表示的1- [1-（3,4-二烷氧基芳基） - 吡啶基甲基] -1H-吡唑化合物，其中A是N或CH; R1是直链或支链饱和或不饱和（C1-C7）烷基或卤素取代的直链或支链饱和或不饱和（C1-C7）烷基; R2是氢原子，（C3-C7）环烷基或（C3-C8）环烷基甲基; R 3，R 4和R 5各自独立地为氢原子，苯基，吡啶基，N-氧代吡啶基，直链或支链，饱和或不饱和的（C1-C7）烷基，（C3-C7）环烷基，（C3-C10）环烷基 ）（C 1 -C 7）烷基氨基羰基，（C 3 -C 7）环烷基氨基，3至7元饱和或不饱和的（C 1 -C 7）烷基氨基， 杂环中含氧，氮或硫的杂环，胍基，脲基，苄基，苄氧基，甲酰基，（C1-C7）烷酰基，（C1-C7）烷氧基，（C1-C7）烷氧基（C1-C7） （C 1 -C 7）烷基，羧基或（C 1 -C 7）烷氧基羰基; R6是吡啶基或N-氧代吡啶基。