公开(公告)号：KR101375288B1

公开(公告)日：2014-03-17

申请号：KR1020120030785

申请日：2012-03-26

Applicant: 한국화학연구원

Inventor： 이선숙 ,  이일영 ,  안기석 ,  정택모 ,  이영국 ,  김창균 ,  임종선 ,  전동주 ,  박보근 ,  정석종

IPC: C01B31/02 ,  B01J8/00 ,  B01F3/12

Abstract: 본 발명은 기능화된 그래핀 화합물의 제조방법에 관한 것으로 구체적으로는 산화 그래핀을 이용하여 분산성이 우수한 그래핀 화합물을 제조하는 방법에 관한 것이다.

公开(公告)号：KR1020130127023A

公开(公告)日：2013-11-22

申请号：KR1020120048230

申请日：2012-05-07

Applicant: 한국화학연구원

Inventor： 박보근 ,  김창균 ,  정택모 ,  전동주 ,  이영국 ,  박주현 ,  강성구

IPC: C07F7/22 ,  C23C16/18

CPC classification number: C07F7/2284 ,  C07F7/2268 ,  C23C16/305 ,  C23C16/45525

Abstract: The present invention relates to a tin precursor represented by chemical formula 1. The tin precursor has an advantage that the addition of separate sulfur is not needed in the process of manufacturing a thin film and can form a high quality tin sulfide thin film by improving the thermal stability and volatility. In chemical formula 1, each of R1 and R2 is independently a C1-C10 linear or branched alkyl group; each of R3 and R4 is independently a C1-C10 linear or branched alkyl group or a C1-C10 alkyl fluoride group; and n is 1-3.

Abstract translation: 本发明涉及由化学式1表示的锡前体。锡前体具有以下优点：在制造薄膜的过程中不需要添加单独的硫，并且可以通过改进形成高质量的硫化锡薄膜 热稳定性和挥发性。 在化学式1中，R 1和R 2各自独立地为C 1 -C 10直链或支链烷基; R 3和R 4各自独立地为C 1 -C 10直链或支链烷基或C 1 -C 10烷基氟基; n为1-3。

公开(公告)号：KR1020130125594A

公开(公告)日：2013-11-19

申请号：KR1020120049237

申请日：2012-05-09

Applicant: 한국화학연구원

Inventor： 박보근 ,  정택모 ,  김창균 ,  전동주 ,  김효숙 ,  이영국 ,  안기석 ,  이선숙 ,  임종선

IPC: C01F5/02 ,  C01F5/00 ,  C23C16/18

CPC classification number: C23C16/403

Abstract: The present invention relates to a magnesium oxide precursor which is denoted by chemical formula 1. The magnesium oxide precursor is thermally stable and highly volatile to obtain a thin film which contains high quality magnesium oxide.

Abstract translation: 本发明涉及由化学式1表示的氧化镁前体。氧化镁前体是热稳定且高挥发性的，以获得含有高质量氧化镁的薄膜。

公开(公告)号：KR1020130124814A

公开(公告)日：2013-11-15

申请号：KR1020120048238

申请日：2012-05-07

Applicant: 한국화학연구원

Inventor： 임종선 ,  정승두 ,  전동주 ,  박보근 ,  정석종 ,  조성윤 ,  민복기

IPC: C07F1/08 ,  C07F7/22 ,  C07F15/04 ,  H01L51/30

CPC classification number: C07D487/22 ,  H01L51/0091 ,  H01L51/0545

Abstract: The present invention relates to a novel preparation method of a benzoporphyrin derivative and the fabrication of an organic thin-film transistor thereby. The novel preparation method of the benzoporphyrin derivative by the present invention remarkably reduces the number of production processes compare to existing preparation method of the benzoporphyrin derivative for economically obtaining the benzoporphyrin derivative which is a target compound. The process is simplified and the facility and production costs for applying the printing method are reduced by dissolving the benzoporphyrin derivative in more than two kinds of mixed organic solvent with different boiling points, and fabricating the organic thin-film transistor using the printing method.

Abstract translation: 本发明涉及一种苯并卟啉衍生物的新型制备方法及其制造有机薄膜晶体管。 本发明的苯并卟啉衍生物的新型制备方法与用于经济地获得作为目标化合物的苯并卟啉衍生物的苯并卟啉衍生物的现有制备方法相比，显着降低了制备方法的数量。 该方法简化，通过将苯并卟啉衍生物溶解在两种以上沸点不同的混合有机溶剂中，并且使用印刷方法制造有机薄膜晶体管来降低印刷方法的设备和生产成本。

公开(公告)号：KR1020130104627A

公开(公告)日：2013-09-25

申请号：KR1020120026274

申请日：2012-03-14

Applicant: 한국화학연구원

Inventor： 정택모 ,  김창균 ,  이영국 ,  안기석 ,  이선숙 ,  박보근 ,  전동주 ,  임종선 ,  정석종 ,  이창완

IPC: H01L21/205

Abstract: PURPOSE: A method for forming a thin film including Sb with an atomic layer deposition method is provided to improve productivity by forming the thin film including Sb at low temperatures through an atomic layer deposition process using a Sb precursor. CONSTITUTION: A substrate is prepared in a vacuum chamber. A Sb precursor material is prepared. A source gas is prepared by the Sb precursor material. A reactive gas including a hydrogen gas is prepared. A purge gas is prepared. A metal precursor gas is prepared by a metal precursor material. A thin film of a Sb-metal monolayer is formed on the substrate by successively supplying the source gas, the reactive gas, the purge gas, and the metal precursor gas to the vacuum chamber.

Abstract translation: 目的：提供一种通过原子层沉积法形成包含Sb的薄膜的方法，以通过使用Sb前体的原子层沉积工艺在低温下形成包含Sb的薄膜来提高生产率。 构成：在真空室中制备基材。 制备Sb前体材料。 源气体由Sb前体材料制备。 制备包括氢气的反应气体。 准备吹扫气体。 通过金属前体材料制备金属前体气体。 通过将源气体，反应气体，吹扫气体和金属前体气体依次供给到真空室，在基板上形成Sb-金属单层薄膜。

公开(公告)号：KR1020080065722A

公开(公告)日：2008-07-15

申请号：KR1020070002715

申请日：2007-01-10

Applicant: 한국화학연구원

Inventor： 전동주 ,  노재성 ,  송종환 ,  이계형 ,  김익연 ,  박창민 ,  소원영 ,  이지선 ,  김은주 ,  강남숙 ,  천혜경 ,  조영식 ,  송진숙 ,  배명애 ,  김지현 ,  조중명 ,  노성구 ,  현영란 ,  이철순 ,  이재일 ,  유성은

IPC: C07D231/12 ,  C07D401/04 ,  C07D403/10 ,  C07D413/04

Abstract: A novel compound is provided to show excellent activity on PDE-4 enzymes and high selectivity on other PDE enzymes, thereby being used as a therapeutic agent of inflammation related diseases, arthritis, atopic dermatitis, leukemia, various cancers and degenerative brain diseases with little side effects. A 1-[1-(3,4-dialkoxyphenyl)-alkyl]-1H-pyrazole compound is represented by a formula(1) and is prepared by reacting a halo-benzyl compound represented by a formula(2) with a pyrazole compound represented by a formula(3). In the formula(1), each R1 and R2 is independently H, linear or branched saturated or unsaturated C1-7 alkyl which may be substituted or unsubstituted by halogen, C3-7 cycloalkyl, (C3-7)cycloalkyl(C1-7)alkyl, aryl or heteroaryl, ar(C1-5)alkyl, or ar(C1-5)alkoxy, or the R1 and R2 may be linked to each other by C1-3 alkylene; each R3, R4 and R5 is independently H, phenyl, pyridinyl, N-oxypyridinyl, linear or branched saturated and unsaturated C1-7 alkyl, C3-7 cycloalkyl, (C3-10)cycloalkyl(C1-7)alkyl, halogen, cyano, nitro, amino, mono- or di(C1-7)alkylamino, mono or di(C1-7)alkylaminocarbonyl, C3-7 cycloalkylamino, 3 to 7-membered saturated or unsaturated hetero-ring including O, N or S, guanidinyl, ureido, benzyl, benzyloxy, formyl, C1-7 alkanoyl, C1-7 alkoxy, (C1-7)alkoxy(C1-7)alkyl, hydroxy(C1-7)alkyl, carboxyl, or (C1-7)alkoxycarbonyl; R6 is linear or branched saturated and unsaturated C1-7 alkyl, C3-7 cycloalkyl, (C3-10)cycloalkyl(C1-7)alkyl, phenyl, phenoxy, benzyl, benzyloxy, C1-7 alkoxy, or (C1-7)alkoxy(C1-7)alkyl. A pharmaceutical composition for treating or preventing diseases related to airway inflammation, arthritis, atopic dermatitis, leukemia, cancer or degenerative brain diseases comprises the 1-[1-(3,4-dialkoxyphenyl)-alkyl]-1H-pyrazole derivative as an effective ingredient.

Abstract translation: 提供了一种新型化合物，以显示对PDE-4酶的优异活性和对其他PDE酶的高选择性，从而被用作炎症相关疾病，关节炎，特应性皮炎，白血病，各种癌症和退行性脑病的治疗剂 效果。 1-（1-（3,4-二烷氧基苯基） - 烷基] -1H-吡唑化合物由式（1）表示，通过式（2）表示的卤代苄基化合物与吡唑化合物 由公式（3）表示。 在式（1）中，每个R 1和R 2独立地为H，可被卤素取代或未取代的直链或支链饱和或不饱和C 1-7烷基，C 3-7环烷基，（C 3-7）环烷基（C 1-7） 烷基，芳基或杂芳基，芳（C 1-5）烷基或芳（C 1-5）烷氧基，或者R 1和R 2可以被C 1-3亚烷基相互连接; 每个R 3，R 4和R 5独立地为H，苯基，吡啶基，N-氧代吡啶基，直链或支链饱和和不饱和C 1-7烷基，C 3-7环烷基，（C 3-10）环烷基（C 1-7）烷基，卤素，氰基 ，硝基，氨基，单或二（C1-7）烷基氨基，单或二（C1-7）烷基氨基羰基，C3-7环烷基氨基，3至7元饱和或不饱和杂环，包括O，N或S，胍基 （C 1-7）烷基，羟基（C 1-7）烷基，羧基或（C 1-7）烷氧基羰基;（C 1-7）烷氧基， R6是直链或支链饱和和不饱和的C1-7烷基，C3-7环烷基，（C3-10）环烷基（C1-7）烷基，苯基，苯氧基，苄基，苄氧基，C1-7烷氧基或（C1-7） 烷氧基（C 1-7）烷基。 用于治疗或预防与气道炎症，关节炎，特应性皮炎，白血病，癌症或退行性脑疾病相关的疾病的药物组合物包括1- [1-（3,4-二烷氧基苯基） - 烷基] -1H-吡唑衍生物作为有效的 成分。

公开(公告)号：KR100753017B1

公开(公告)日：2007-08-30

申请号：KR1020060046860

申请日：2006-05-25

Applicant: 한국화학연구원

Inventor： 노재성 ,  전동주 ,  송종환 ,  이계형 ,  박창민 ,  소원영 ,  강남숙 ,  홍석주 ,  천혜경 ,  조영식 ,  김기영 ,  배명애 ,  송진숙 ,  노성구 ,  현영란 ,  이운영 ,  김용은 ,  강봉균 ,  이혜련 ,  유성은

IPC: A61K31/437 ,  A61P35/00

Abstract: A pharmaceutical composition for treating or preventing arthritis, atopic dermatitis, tumor and degenerative brain diseases comprising 7-(3,4-Dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidine compounds is provided to inhibit activity of PDE-4(phosphodiesterase-4) and reduce side effects such as vomiting by reducing HARBS(high-affinity rolipram binding sites) affinity. The pharmaceutical composition for treating or preventing arthritis, atopic dermatitis, tumor and degenerative brain diseases comprises 7-(3,4-Dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidine compounds represented by the formula(1), wherein R1 and R2 are independently hydrogen atom, linear or branched saturated or unsaturated (C1-C7)alkyl, linear or branched saturated or unsaturated (C1-C7)alkyl containing halogen atom, (C3-C7)cycloalkyl, 3-membered to 7-membered heterocycloalkyl containing oxygen, nitrogen or sulfur in a hetero aromatic ring, (C4-C10)cycloalkyl(C1-C7)alkyl, 3-membered to 7-membered heterocycloalkyl(C1-C7)alkyl containing oxygen, nitrogen or sulfur in a hetero ring, phenyl, benzyl or allyl group; R3 is hydrogen atom, halogen atom, formyl, linear or branched and saturated or unsaturated (C1-C7)alkyl, (C1-C7)alkylketone, (C1-C7)alkoxy, (C1-C7)alkoxy (C1-C7)alkyl, hydroxy(C1-C7)alkyl group, carboxylic acid, carboxyl(C1-C7)alkylester, carboxyl(C1-C7)alkylamide, amino, or mono or di(C1-C7)alkylaminocarbonyl; and R4 is hydrogen atom, formyl, linear or branched saturated or unsaturated (C1-C7)alkyl, (C3-C7)cycloalkyl, (C1-C7)alkoxy, (C1-C7)alkoxy (C1-C7)alkyl, hydroxy(C1-C7)alkyl ketone, (C1-C10)alkylcarboxylic acid, carboxyl(C1-C10)alkylester, carboxyl(C1-C10)alkylamide, amino, mono or di(C1-C7)alkylamino, mono or di(C1-C7)alkylaminocarbonyl, (C3-C7)cycloalkylamine, morpholine, morpholine oxide, piperidine, piperazine, piperazine oxide or aryl group.

Abstract translation: 用于治疗或预防关节炎，特应性皮炎，肿瘤和退行性脑疾病，其包括7-（3,4-二烷氧基） - 吡唑并提供[1,5-a]嘧啶化合物抑制PDE-4的活性（phosphodiesterase-的药物组合物 4）并通过减少HARBS（高亲和力咯利普兰结合位点）亲和力来减少副作用，例如呕吐。 用于治疗或预防关节炎，特应性皮炎，肿瘤和退行性脑疾病的药物组合物包含7-（3,4-二烷氧基） - 吡唑并[1,5-a]嘧啶化合物由式（1）表示，其中R1和R2 （C 1 -C 7）烷基，含有卤素原子的直链或支链饱和或不饱和（C 1 -C 7）烷基，（C 3 -C 7）环烷基，含有3至7元杂环烷基的3元至7元杂环烷基 （C4-C10）环烷基（C1-C7）烷基，在杂环中含有氧，氮或硫的3元至7元杂环烷基（C1-C7）烷基，苯基 ，苄基或烯丙基; （C 1 -C 7）烷基，（C 1 -C 7）烷氧基，（C 1 -C 7）烷氧基（C 1 -C 7）烷基，（C 1 -C 7）烷氧基， （C 1 -C 7）烷基，羧酸，羧基（C 1 -C 7）烷基酯，羧基（C 1 -C 7）烷基酰胺，氨基或单或二（C 1 -C 7）烷基氨基羰基; （C 1 -C 7）烷基，（C 3 -C 7）环烷基，（C 1 -C 7）烷氧基，（C 1 -C 7）烷氧基（C 1 -C 7）烷基，羟基（C 1 -C 7）烷基， C1-C7）烷基酮，（C1-C10）烷基羧酸，羧基（C1-C10）烷基酯，羧基（C1-C10）烷基酰胺，氨基，单或二（C1-C7）烷基氨基，单或二（C1-C7 ）烷基氨基羰基，（C3-C7）环烷基胺，吗啉，氧化吗啉，哌啶，哌嗪，哌嗪氧化物或芳基。

公开(公告)号：KR100689961B1

公开(公告)日：2007-03-08

申请号：KR1020050018325

申请日：2005-03-04

Applicant: 한국화학연구원

Inventor： 노재성 ,  전동주 ,  송종환 ,  이계형 ,  정준원 ,  박창민 ,  정순민 ,  김지영 ,  강남숙 ,  홍석주 ,  천혜경 ,  남지연 ,  장범수 ,  곽현정 ,  송진숙 ,  허준영 ,  양승돈 ,  전영호 ,  노성구 ,  이태규 ,  현영란 ,  조중명 ,  허용석 ,  윤정민 ,  유성은

IPC: C07D277/42 ,  A61P11/06 ,  A61P25/28

Abstract: 본 발명은 하기의 화학식 1로 표시되는 신규한 4-(3,4-디알콕시페닐)-2-아미노티아졸 화합물 또는 그의 약제학적으로 허용 가능한 염, 이의 제조 방법 및 이를 유효성분으로 함유하는 것을 특징으로 하는 천식 및 만성폐쇄성 폐질환(Chronic Obstructive Pulmonary Disease)을 포함한 염증관련 질환의 치료 및 알쯔하이머를 포함한 중추신경계통 질환의 치료, 예방을 위한 약제학적 조성물에 관한 것이다.
[화학식 1]

4-(3,4-디알콕시페닐)-2-아미노티아졸, PDE-4, 천식, 만성폐쇄성 폐질환, 염증관련 질환, 중추신경계 질환, 알쯔하이머.

公开(公告)号：KR1020040092186A

公开(公告)日：2004-11-03

申请号：KR1020030026416

申请日：2003-04-25

Applicant: 한국화학연구원

Inventor： 전동주 ,  김형래 ,  송종환 ,  박관용 ,  정순민 ,  황인택

IPC: A01N43/90

Abstract: PURPOSE: Provided are 9-(5-isoxazolemethoxyphenyl)imino-8-thia-1,6-diazabicyclo(4.3.0)nonan-7-one derivatives which have herbicidal activity and a herbicidal composition containing the same as active ingredient. The derivatives have high stability to rice and excellent herbicidal effect. CONSTITUTION: 9-(5-isoxazolemethoxyphenyl)imino-8-thia-1,6-diazabicyclo(4.3.0)nonan-7-one derivative is represented by the formula(1), wherein R is C1-C5 alkyl group, phenyl group or substituted phenyl group in which the substituted phenyl group has a substituent selected from C1-C3 alkoxy group, halogen atom, cyano group and carboxylic acid ester group. The herbicidal composition is characterized by containing the 9-(5-isoxazolemethoxyphenyl)imino-8-thia-1,6-diazabicyclo(4.3.0)nonan-7-one derivative as active ingredient.

Abstract translation: 目的：提供具有除草活性的9-（5-异恶唑甲氧基苯基）亚氨基-8-硫杂-1,6-二氮杂双环（4.3.0）壬-7-酮衍生物和含有与活性成分相同的除草组合物。 该衍生物对水稻的稳定性高，除草效果好。 构型：9-（5-异恶唑甲氧基苯基）亚氨基-8-硫杂-1,6-二氮杂双环（4.3.0）壬-7-酮衍生物由式（1）表示，其中R是C1-C5烷基，苯基 基团或取代的苯基，其中取代的苯基具有选自C 1 -C 3烷氧基，卤素原子，氰基和羧酸酯基的取代基。 除草组合物的特征在于含有9-（5-异恶唑甲氧基苯基）亚氨基-8-硫杂-1,6-二氮杂双环（4.3.0）壬-7-酮衍生物作为活性成分。

公开(公告)号：KR1020040086696A

公开(公告)日：2004-10-12

申请号：KR1020030021052

申请日：2003-04-03

Applicant: 한국화학연구원

Inventor： 전동주 ,  김형래 ,  송종환 ,  장규환 ,  황인택

IPC: C07D405/12

Abstract: PURPOSE: Herbicidal2-(5-oxiranylmethoxyphenyl)-4,5,6,7-tetrahydro-2H-indazole derivatives are provided, which compounds have improved herbicidal effects and selectivity, so that the compounds can selectively kill weeds. CONSTITUTION: The herbicidal2-(5-oxiranylmethoxyphenyl)- 4,5,6,7-tetrahydro-2H-indazole derivatives represented by formula (1) are provided, wherein R1, R2 and R3 are independently hydrogen, C1-C5 alkyl, phenyl or substituted phenyl with 1 to 3 of halogen atoms. The method for preparing the herbicidal2-(5-oxiranylmethoxyphenyl)- 4,5,6,7-tetrahydro-2H-indazole derivatives of formula (1) comprises the steps of: reacting a compound of formula (2) with allyl halide in the presence of base to prepare a compound of formula (3); and introducing epoxy group into a double bond of the compound of formula (3), wherein X is halogen.

Abstract translation: 目的：提供除草剂2-（5-环氧乙烷基甲氧基苯基）-4,5,6,7-四氢-2H-吲唑衍生物，该化合物具有改善的除草效果和选择性，使得化合物可以选择性地杀死杂草。 构成：提供由式（1）表示的除草2-（5-环氧乙烷基甲氧基苯基）-4,5,6,7-四氢-2H-吲唑衍生物，其中R 1，R 2和R 3独立地是氢，C 1 -C 5烷基，苯基 或具有1至3个卤素原子的取代的苯基。 制备式（1）的除草-2-（5-环氧乙烷基甲氧基苯基）-4,5,6,7-四氢-2H-吲唑衍生物的方法包括以下步骤：使式（2）的化合物与烯丙基卤在 碱的存在以制备式（3）的化合物; 并将环氧基引入到式（3）化合物的双键中，其中X是卤素。