US10435804B2
A method of and apparatus for efficient on-demand production of H2 and O2 from water and heat using environmentally safe metals are disclosed. In one aspect, the apparatus for hydrogen generation through water-decomposition reaction includes a main reactor, an oxidizer reactor, and a computer-control system. The computer system is configured to control each of the components of the hydrogen gas production system for stable hydrogen-gas production.
US10435800B2
An electrolyzer operates within an energy system, for example to provide grid services, energy storage or fuel, or to produce hydrogen from electricity produced from renewable resources. The electrolyzer may be configured to operate at frequently or quickly varying rates of electricity consumption or to operate at a specified power consumption. In one process of operating an electrolyzer, a series of dispatches is received indicating a specified power consumption for a period of time. The dispatches may occur at least once every 30 minutes. The electrolyzer is operated according to the dispatches. Hydrogen produced by the electrolyzer is discharged to a natural gas system.
US10435799B2
A carboxylic acid-containing composition, which composition contains an aldehyde, is purified in a process, which process comprises introducing the carboxylic acid-containing composition and an aqueous electrolyte into an electrolytic cell comprising electrodes; electrochemically oxidizing the aldehyde in the electrolytic cell to obtain an electrochemically oxidized product composition comprising a carboxylic acid derived from the aldehyde; and, optionally, separating carboxylic acid from the electrochemically oxidized product composition.
US10435792B2
A laminate includes: a substrate; and a metallic coating that is formed from copper powder containing 0.002% to 0.020% by weight of phosphorus and having been subjected to reduction treatment, the metallic coating being deposited on the substrate.
US10435790B2
A method for depositing a film by plasma-enhanced subatmospheric-pressure atomic layer deposition (subatmospheric PEALD) is conducted using capacitively coupled parallel plate electrodes with a gap of 1 mm to 5 mm, wherein one cycle of subatmospheric PEALD includes: supplying a precursor in a pulse to the reaction chamber; continuously supplying a reactant to the reaction chamber; continuously supplying an inert gas to the reaction chamber; continuously controlling a pressure of the reaction chamber in a range of 15 kPa to 80 kPa; and applying RF power for glow discharge in a pulse to one of the parallel plate electrodes.
US10435784B2
A process kit ring for use in a plasma processing system is disclosed herein. The process kit ring includes an annular body and one or more hollow inner cavities. The annular body is formed from a plasma resistant material. The annular body has an outer diameter greater than 200 mm. The annular body includes a top surface and a bottom surface. The top surface is configured to face a plasma processing region of a process chamber. The bottom surface is opposite the top surface. The bottom surface is substantially perpendicular to a centerline of the body. The bottom surface is supported at least partially by a pedestal assembly. The one or more hollow inner cavities are formed in the annular body about the centerline. The one or more hollow inner cavities are arranged in a circle within the annular body.
US10435780B2
A rotomolding tool having a textured surface is provided. The tool comprises a shell having a body portion and an upper mold surface having a grain texture, at least the body portion comprising a nickel-iron alloy having a coefficient of thermal expansion of at most 5.O×10−6 in/in/° F. at temperatures between 100° and 500° F.
US10435775B2
Methods of refining the grain size of titanium and titanium alloys include multiple upset and draw forging. Titanium and titanium alloy workpieces are heated to a workpiece forging temperature within a workpiece forging temperature range in the alpha+beta phase field. The workpiece may comprise a starting cross-sectional dimension. The workpiece is upset forged in the workpiece forging temperature range. After upsetting, the workpiece is multiple pass draw forged in the workpiece forging temperature range. Multiple pass draw forging may comprise incrementally rotating the workpiece in a rotational direction followed by draw forging the workpiece after each incremental rotation. Incrementally rotating and draw forging the workpiece is repeated until the workpiece comprises substantially the same starting cross-sectional dimension.
US10435771B2
An alloy composition that includes about 1 to about 9 atomic percent aluminum (Al), about 25 to about 33 atomic percent titanium (Ti), about 10 to about 33 atomic percent vanadium (V), about 5 to about 10 atomic percent zirconium (Zr) and about 25 to about 33 atomic percent niobium (Nb).
US10435767B2
A low-flux converting process for PGM collector alloy. The process includes feed introduction into a molten alloy pool, oxygen injection into the pool, tapping the slag, and tapping the PGM-enriched alloy. The collector alloy contains no less than 0.5 wt % PGM, 40 wt % iron, and 0.5 wt % nickel. If added flux material contains more than 10 wt % silica and 10 wt % CaO/MgO, the feed contains no more than 20 parts by weight added flux per hundred collector alloy. The process can also include using a refractory protectant in the converter; melting partially pre-oxidized collector alloy to form the initial molten alloy pool; magnetic separation of slag; recycling part of the slag to the converter; smelting catalyst material in a primary furnace to produce the collector alloy; and/or smelting the converter slag in a secondary furnace with slag from the primary furnace.
US10435765B2
A wire rod for a steel cord has a wire diameter R of 3.5 mm to 8.0 mm, and includes, in a chemical composition, by mass %: C: 0.70% to 1.20%; Si: 0.15% to 0.60%; Mn: 0.10% to 1.00%; N: 0.0010% to 0.0050%; Al: more than 0% and 0.0100% or less; and a remainder of Fe and impurities, in which a surface part and a central part are included, a thickness of the surface part is 50 μm to 0.20×R, the central part includes a pearlite structure in a proportion of 95% to 100% by area %, a C content of the surface part is 40% to 95% of a C content of the central part, and a ratio of a thickness of a lamellar cementite at a center of the thickness of the surface part to a thickness of a lamellar cementite in the central part is 95% or less, whereby high strength and workability can be achieved even after a finish drawing process and cracking or the like caused by a delamination phenomenon can be prevented.
US10435757B1
Provided herein are methods of measuring C19MC miRNA amount and/or expression in a post-natal cell and/or tissue. Provided herein are methods of measuring CpG methylation of the upstream C19MC miRNA promoter region in a post-natal cell and/or tissue. Also provided herein are methods of treating a cell, population thereof, and/or a subject in need thereof by administering a C19MC miRNA inhibitor or CRISPR to suppress the expression of specific miRNA within the C19MC or the entire C19MC cluster, population thereof, and/or the subject in need thereof.
US10435753B2
The present invention provides methods and materials related to the detection of colorectal neoplasm-specific markers in or associated with a subject's stool sample. In particular, the present invention provides methods and materials for identifying mammals having a colorectal neoplasm by detecting the presence of exfoliated epithelial markers (e.g., human DNA, tumor assoicated gene alterations, tumor associated proteins) and blood markers (e.g., homoglobin, serum proteins) in a stool sample obtained from the mammal.
US10435750B2
The present invention relates to the technical field of organ and tissue transplantation and specifically to methods allowing rejection of transplanted organs and tissues by a transplant patient. The present invention provides methods for non-invasive and ex vivo or in vitro detection of the presence or absence of transplant rejection, i.e. transplant health or rejection. The present methods allow for effective and continuous monitoring of transplant status with a minimal or absent discomfort for a transplant patient.
US10435749B2
The present invention provides compositions and methods based on genetic polymorphisms that are associated with coronary heart disease (particularly myocardial infarction), aneurysm/dissection, and/or response to drug treatment, particularly statin treatment. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
US10435743B2
The invention provides methods and materials that use observation of DNA characteristics to obtain information relating to the age of individuals. The instant disclosure identifies 88 sites in or near 80 genes for which the degree of cytosine methylation in epithelial and/or white blood cells is significantly correlated with age. In illustrative embodiments of the invention, cytosine methylation patterns the promoters of the EDARADD, TOMILI, and NPTX2 genes are used to predict the age of an individual with a high degree of accuracy.
US10435739B2
Provided are methods and devices for single-molecule genomic analysis. In one embodiment, the methods entail processing a double-stranded nucleic acid and characterizing said nucleic acid. These methods are useful in, e.g. determining structural variations and copy number variations between individuals.
US10435729B2
The present invention relates to the production of the disaccharide kojibiose which is known to be a powerful prebiotic. The invention indeed discloses the generation of genetically modified sucrose phosphorylases which convert—via a transglycosylation reaction—sucrose into kojibiose in a very efficient manner. Hence, the present invention relates to a cost-effective production method of kojibiose which is useful within industry.
US10435723B2
The present invention relates to a method for preparing an adipate ester or thioester. The invention further relates to a method for preparing adipic acid from said ester or thioester. Further the invention provides a number of methods for preparing an intermediate for said ester or thioester. Further the invention relates to a method for preparing 6-amino caproic acid (6-ACA), a method for preparing 5-formyl valeric acid (5-FVA), and a method for preparing caprolactam. Further, the invention relates to a host cell for use in a method according to the invention.
US10435717B2
The present invention provides genetically modified eukaryotic host cells that produce isoprenoid precursors or isoprenoid compounds. A subject genetically modified host cell comprises increased activity levels of one or more of mevalonate pathway enzymes, increased levels of prenyltransferase activity, and decreased levels of squalene synthase activity. Methods are provided for the production of an isoprenoid compound or an isoprenoid precursor in a subject genetically modified eukaryotic host cell. The methods generally involve culturing a subject genetically modified host cell under conditions that promote production of high levels of an isoprenoid or isoprenoid precursor compound.
US10435715B2
Described herein are methods and vectors for rational, multiplexed manipulation of chromosomes within open reading frames (e.g., in protein libraries) or any segment of a chromosome in a cell or population of cells, in which various CRISPR systems are used.
US10435712B2
The present invention relates to the discovery of a high titer hybrid-virus vector that gives rise to high titer virus like vesicles (VLVs) that can be used as a vaccine. The invention includes compositions and methods of generating an evolved hybrid-virus vector vaccine and selecting high titer VLVs, methods of treating and/or preventing or immunizing against, a specific disease or disorder, and methods of inducing a memory T cell and B cell immune response in a subject administered the VLV composition produced thereby. Furthermore, the invention encompasses a pharmaceutical composition for vaccinating a subject as well as a high titer protein expression system.
US10435709B2
A nucleic acid containing a dopamine receptor type 2-specific promoter (D2SP) is provided. In certain embodiments, the nucleic acid includes a dopamine receptor type 2-specific promoter (D2SP), wherein the D2SP does not include exon 1 of a D2 receptor gene, wherein the D2SP comprises a Kozak sequence, and wherein the D2SP includes a nucleotide sequence having at least 95% sequence identity to the nucleotide sequence set forth in SEQ ID NO: 1. Also provided are expression vectors, genetically modified host cells and kits that include the subject nucleic acid.
US10435706B2
Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
US10435705B2
The present invention relates to a method of increasing resistance against fungal pathogens of the family Phacosporaceae in plants and/or plant cells. This is achieved by increasing the expression of an HCP6 protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding an HCP6 protein.
US10435704B2
A process of producing a recombinant glycoprotein in a plant, in cells of a plant, or in plant cells is provided. The process comprises expressing in said plant, in cells of said plant or in said plant cells a nucleic acid sequence encoding a polypeptide having an N-glycosylation site and co-expressing a nucleic acid sequence encoding a heterologous single-subunit oligosaccharyltransferase.
US10435701B2
Provided are methods and compositions to improve fungal disease resistance and/or nematode resistance in various crop plants. Also provided are combinations of compositions and methods to improve fungal disease resistance and/or nematode resistance in various crop plants.
US10435686B2
This invention discloses novel microRNAs and their precursors, and recombinant DNA constructs including such novel miRNAs, miRNA precursors, miRNA promoters, and miRNA recognition sites corresponding to the miRNAs. Included are novel miRNA and miRNA precursors that exhibit nutrient-responsive expression. Also disclosed are miRNA decoy sequences. Further provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention and methods of controlling gene expression using recombinant DNA constructs of this invention.
US10435676B2
The present invention relates to a variant of Terminal deoxynucleotidyl Transferase (TdT) which (i) comprises the amino acid sequence as set forth in SEQ ID Nº 2 or a functionally equivalent sequence, with at least an amino acid substitution at position corresponding to residue C302 or functionally equivalent residue, wherein the position is numbered by reference to the amino acid sequence set forth in SEQ ID Nº 1, (ii) is able to synthesize a nucleic acid fragment without template and (iii) is able to incorporate a modified nucleotide into the nucleic fragment.
US10435675B2
A composition having nucleic acid polymerase activity, which comprises an active nucleic acid polymerase and an excess amount of a non-functional mutant nucleic acid polymerase protein, wherein the non-functional mutant nucleic acid polymerase protein stabilizes the active nucleic acid polymerase against loss of polymerase activity.
US10435674B2
The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents.
US10435669B2
The invention relates to the field of microbiology, specifically to a bacteriophage, polypeptide and a corresponding polynucleotide, a nucleic acid molecule and/or vector and/or cell comprising such polynucleotide, a composition comprising said bacteriophage, polypeptide, polynucleotide, construct, vector and/or cell, preferably for preventing, treating or diagnosing contamination with and/or a condition in an individual related to Salmonella. The invention further relates to an antimicrobial composition for medical use or for use as a food additive or as a disinfectant, or for detecting bacteria, preferably in a diagnostic application, wherein said antimicrobial composition comprises a bacteriophage, polypeptide, corresponding polynucleotide, construct and/or vector and/or cell comprising such polypeptide and/or composition according to the present invention.
US10435666B2
The first method to cause a culture of human and other primate stem cells to directly and uniformly differentiate into a committed cell lineage is disclosed. Treatment of primate stem cells with a single protein trophoblast induction factor causes the cells to transform into human trophoblast cells, the precursor cells of the placenta. Several protein factors including bone morphogenic protein 4 (BMP4), BMP2, BMP7, and growth and differentiation factor 5 can serve as trophoblast-inducting factors.
US10435664B2
System and method for production of on-demand proteins in a portable unit for point of care delivery
A portable and mobile bioprocessing system and method for protein manufacturing that is compact, integrated and suited for on-demand production of any type of proteins and for delivery of the produced proteins to patients or for assay purposes. The portable system and method can also be used for efficient on-demand production of any type of protein with point-of-care delivery.
US10435663B2
This disclosure describes an improved heat transfer system for use in reaction vessels used in chemical and biological processes. In one embodiment, a heat transfer baffle comprising two sub-assemblies adjoined to one another is provided.
US10435658B2
A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.
US10435652B2
[Problem to be Solved] To provide a liquid laundry detergent composition for clothing which can remove bacteria from the clothing effectively during washing and also impart an excellent antibacterial effect to the clothing after washing.[Solution] A liquid laundry detergent composition for clothing comprising: a bacteria-eliminating active agent, at least one cationic polymer selected from the following components (a), (b) and (c), and a surfactant: the component (a): diallylamine hydrochloride polymers, diallylamine polymers, methylallylamine hydrochloride polymers, diallyldimethylammonium chloride polymers, diallylmethylethyl sulfate polymers, diallylamine hydrochloride-sulfur dioxide copolymers, diallylamine acetate-sulfur dioxide copolymers and the like; the component (b) acrylamide-diallylamine hydrochloride copolymers, acrylamide-diallyldimethylammonium chloride copolymers and the like; the component (c) allylamine hydrochloride polymers, allylamine polymers, allylamine hydrochloride-diallylamine hydrochloride copolymers, allylamine acetate-diallylamine acetate copolymers and the like.
US10435649B2
The cleaning performance of washing and cleaning agents, in particular with respect to bleachable stains, was to be intensified without resulting in damage, in the context of use, to the textile treated therewith. This was achieved substantially by employing a bleaching-active species generated electrolytically from an organic mediator compound using a redox reaction.
US10435628B2
The invention relates to a polymerizable LC medium with negative optical dispersion, a polymer film with negative optical dispersion obtainable from such a medium, and the use of the polymerizable LC medium and polymer film in optical, electro optical, electronic, semiconducting or luminescent components or devices.
US10435624B2
A hydraulic fracturing and gravel packing proppant composite with protectant on the surface of the proppant and the composition matters of the protectant and proppant. The surface protectant reduces the generation of dust/fines from the proppant caused by abrasion and impingement during transportation and conveyance, particularly pneumatic transfer.
US10435620B2
Provided are acidic treatment fluids comprising a weakly emulsifying surfactant, an aqueous base fluid, and an acid. In some embodiments, the treatment fluids are capable of forming short-lived oil-in-acid emulsions due, at least in part, to the interaction of at least a portion of the weakly emulsifying surfactant with one or more oil or gas molecules within a subterranean formation.
US10435609B2
The present invention relates to a composition comprising (i) at least 10 wt % of an inorganic and/or organic, water soluble salt, based on the total weight of the composition; (ii) water; and (iii) an ether monocarboxylic acid. Further aspects of the invention relate to the use of an ether monocarboxylic acid of the invention, an amide, a salt or an ester thereof as a lubricant preferably in salt based drilling systems.
US10435608B2
Included are methods and systems for drilling in a subterranean formation. A method comprises providing a drilling fluid comprising an aqueous base fluid and a betaine shale stabilizer; placing the drilling fluid into the subterranean formation; and drilling a wellbore in the subterranean formation. A drilling system comprises a drilling fluid comprising an aqueous base fluid and a betaine shale stabilizer; a drilling assembly; a drill string coupled to the drilling assembly; a pumping system fluidically coupled to the drill string, wherein the pumping system is capable of pumping the drilling fluid through the drill string.
US10435606B2
Disclosed is a cable comprising a core and a PCM layer surrounding the core wherein the PCM layer consists of a PCM composition wherein the PCM composition comprises a PCM and an ethylene copolymer; and the core consists of a yarn, strand, or wire each made of a natural or synthetic polymeric material or a metal. The invention is useful for thermal management in a variety of applications in such as, for example, automotive, building, packaging, garments, and footwear.
US10435602B2
The invention relates to hotmelt adhesives based on polyesters, having low VOC and fogging values. In particular, the invention relates to reactive hotmelt adhesives including polyesters containing at least 50 mole percent, based on the polycarboxylic acid components, of terephthalic acid or a derivative thereof and containing at least 40 mole percent, based on the polyol components, of diols of the formula HO—(CH2)x—OH with x≥6.
US10435598B2
Provided are an adhesive bonding composition for optical use and a multistage curing method thereof, the composition including a methacrylate-based monomer and an acrylate-based monomer, in which a weight ratio of the methacrylate-based monomer to the acrylate-based monomer ranges from about 1:1 to about 1:10.
US10435596B2
The present invention relates to a pressure-sensitive adhesive composition and a pressure-sensitive adhesive film including the same, and provides a pressure-sensitive adhesive composition and a pressure-sensitive adhesive film which may prevent damage to an element from moisture contained in the composition, ionic substances, and other foreign substances, and effectively block electrochemical corrosion, thereby improving a lifetime and durability of an organic electronic device.
US10435592B2
An object of the present invention is to provide a primer composition for application between the base film and the adhesive layer of an adhesive tape that can improve the adhesion between the base film and the adhesive layer of the adhesive tape and an adhesive tape prepared by using the primer composition. A primer composition, comprising 100 parts by mass (as solid matter) of a graft polymer of a natural rubber graft-polymerized with 15 to 65 mass % of methyl methacrylate and 25 to 300 parts by mass of a carboxyl group-modified acrylonitrile butadiene rubber.
US10435591B2
An adhesive tape substrate production method disclosed in the present description includes the steps of: decreasing the amount of a sizing agent contained in a glass cloth by heat; impregnating the glass cloth for which the amount of the sizing agent has been decreased with a dispersion of a fluorine resin; and heating the impregnated glass cloth to a temperature equal to or higher than a melting point of the fluorine resin. Thus, an adhesive tape substrate including the glass cloth impregnated with the fluorine resin is obtained. This method are more productive of adhesive tape substrates and adhesive tapes than conventional methods. In addition, adhesive tape substrates and adhesive tapes for which the occurrence of defects in appearance are reduced can be produced.
US10435585B2
A curable composition comprises a cationic polymerizable material. The curable composition further comprises a diluent component comprising a silane compound having a single silicon-bonded cationic polymerizable group. A method of forming a cured article with the curable composition is also disclosed. The method comprises applying the curable composition on a substrate to form a film. The method further comprises curing the film on the substrate to form the cured article. The present invention also provides the cured article formed in accordance with the method.
US10435581B2
Coating composition, method for manufacturing film using the same, and coated article using the same
Provided are a chromium-free fluoropolymer-containing primer composition, which can provide a coated article having excellent higher corrosion resistance by forming a fluoropolymer coating film, and a primer layer having sufficient adhesive strength to the fluoropolymer coating film on the surface of a substrate such as metal, glass, ceramic and heat resistant plastics, a method for manufacturing a coating film using the same, and a coated article using the same. The coating composition contains at least one kind of a fluoropolymer component selected from a reactive functional group-containing fluoropolymer, and a fluoropolymer having a melt flow rate (MFR), measured under a load of 5 kg and at 372° C., in accordance with ASTM D1238, of 10 to 100 g/10 minutes, and an organic titanate, wherein content of titanium contained in the organic titanate, relative to the fluoropolymer component, is 1 to 40% by weight.
US10435579B2
Described herein are compositions comprising hole carrier materials, typically conjugated polymers, and fluoropolymers ink compositions comprising hole carrier materials and fluoropolymers, and uses thereof, for example, in organic electronic devices.
US10435578B2
A printing ink composition includes a metal salt of a metal ion and a counter ion, and a viscosity adjusting agent. The metal ion is present as a metal complex of the metal ion and the viscosity adjusting agent, the viscosity adjusting agent includes at least one functional ligand, where the functional ligand may be a monofunctional ligand having one functional group and multifunctional ligands having more than one functional groups.
US10435576B2
A water soluble polymer composition includes a water soluble polymer and a sugar and may be used as a support in additive manufacturing processes.
US10435574B2
A thermal ink jet ink composition include a volatile organic solvent, a binder resin, a dye, a humectant in an amount from 1% to 40% by weight of the ink composition, and an additive for extending the decap time. The additive is present in an amount greater than 0.1% by weight of the thermal ink jet ink composition. The additive is selected from fluorinated surfactants, ionic surfactants, and nonionic surfactants.
US10435568B2
The present invention relates to antifouling coatings capable of being switched by using heat or ultraviolet light. Prior to switching, the coating includes an onium cation component having antimicrobial and antibacterial properties. Upon switching, the coating is converted to a conjugated polymer state, and the cationic component is released with any adsorbed biofilm layer. Thus, the coatings herein have switchable and releasable properties. Methods of making and using such coatings are also described.
US10435564B2
Provided is a compound capable of exhibiting different changes in hue with one kind of molecule. The compound has julolidine structures, and is represented by a general formula (1): wherein each of Q and Q1 represents C(R) or N; R represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 6 carbon atoms, or a carboxyl group, where two Rs may bind to each other to form a ring; R1 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 6 carbon atoms, or a carboxyl group, where two R1s may bind to each other to form a ring; n represents a number of 0 to 3; and m represents a number of 0 to 3.
US10435559B2
Described herein are polyamide compositions and processes for producing polyamide compositions, comprising: (i) a polyamide, (ii) an olefin-maleic anhydride copolymer (on its own or in a master batch form), and (iii) an impact modifier (or an elastomeric polymer with an optional compatibilizer), which exhibit enhanced ambient and low temperature impact strength complimented by excellent thermal, tensile and flexural properties.
US10435556B2
A biodegradable polyester composition based on a total weight of the biodegradable polyester composition, including a weight content of a cyclic ester compound having a structure shown as formula (I) which is 100 ppm-950 ppm; and based on the total weight of the biodegradable polyester composition, a weight content of tetrahydrofuran is 3 ppm-200 ppm is provided. The cyclic ester compound and tetrahydrofuran is added into the composition and controlling the content of the cyclic ester compound and the content of tetrahydrofuran in a certain range in the composition to realize an anti-thermal oxidative aging property of the biodegradable polyester composition. In addition, a film is prepared by blow molding or a part is prepared by injection molding after being digested with 95% ethanol at 40° C. for 240 hours.
US10435546B2
A pneumatic tire having a tire component prepared by use of a rubber composition according to the present invention which comprises: a polybitadiene (i) which satisfies conditions of (A) a Mooney viscosity (ML1+4, 100° C.) of 43 to 70, (B) a ratio (Tcp/ML1+4, 100° C.) of 5% by mass toluene solution viscosity (Tcp) to Mooney viscosity (ML1+4, 100° C.) of 0.9 to 1.7, (C) a stress relaxation time (T80), being a time until a torque is attenuated by 80% assuming that the torque at the end of ML1+4, 100° C. measurement is 100%, of 10.0 to 40.0 seconds, (D) a molecular weight distribution (Mw/Mn) of 2.50 to 4.00, and (F) a proportion of cis-structure in microstructural analysis of not more than 98 mol %; another rubber (ii); and a rubber reinforcing material (iii), is excellent in processability and properties of tire.
US10435537B2
Disclosed is a binder of vegetable origin based on oil, modified vegetable resin and optionally a heat stabilizer. Also disclosed are leakproofing membrane compositions, soundproofing membrane compositions, liquid sealing system compositions, asphalt mix coating compositions, asphalt coating compositions, primer compositions, varnish compositions, mastic compositions, adhesive compositions or binder emulsion compositions which comprise said binder. In addition, a method is disclosed for reducing the amount of bitumen of petroleum origin in said compositions.
US10435536B2
A method of vulcanizing rubber is disclosed. The method can include adding to un-vulcanized rubber a complex comprising mercaptobenzothiazole chemically bound to zinc oxide, and vulcanizing the rubber.
US10435534B2
In an embodiment, a dielectric substrate comprises an unsintered polytetrafluoroethylene; and a high dielectric constant filler, wherein the dielectric constant of the high dielectric constant filler is greater than or equal to 35; wherein the dielectric substrate has a specific gravity of greater than or equal to 90% of a calculated theoretical density of the dielectric substrate, wherein the theoretical specific gravity is calculated based on a measured specific gravity of the high dielectric constant filler, the specific gravity of the unsintered polytetrafluoroethylene, and the relative weight fractions of the unsintered polytetrafluoroethylene and the high dielectric constant filler; and wherein the dielectric substrate has a dielectric constant of greater than or equal to 11.5 as determined at a frequency of 10 GHz.
US10435533B2
Provided is a resin composite material having a small number of voids and excellent tenacity. The resin composite material may be one obtained by mixing a carbon material having a graphene structure and having a content of less than 1 weight % of a volatile component volatilizable at 200° C. and a thermoplastic resin. The resin composite material may be a resin composite material including a carbon material having a graphene structure and a thermoplastic resin, the resin composite material containing 5 parts by weight or more of the carbon material per 100 parts by weight of the thermoplastic resin and having a breaking strain of 50% or more as measured according to JIS K 7161.
US10435525B2
Hydrophobic breathable film based on a polymer mixture of A) at least one hydrophilic elastomer block copolymer made of at least one polyamide block and at least one polyalkylene oxide block and B) at least one thermoplastic polymer, which regulates the steam-permeability of the breathable film.
US10435524B2
The present invention relates to a process for the manufacture of a long glass fiber reinforced polypropylene composition at a line speed of at least 6.7 m/s comprising the steps of a) providing at least one continuous glass multifiber strand, b) applying from 0.5 to 20 wt. % based on the weight of the composition of an impregnating agent to said at least one continuous multifiber strand, c) applying a sheath of a polypropylene composition around the strand obtained in step b) so as to form a sheathed continuous multifiber strand, wherein the impregnating agent contains at least 90 wt. % of microcrystalline wax based on the weight of the impregnating agent.
US10435516B2
The present disclosure provides methods and compositions for directed to synthetic block copolymer proteins, expression constructs for their secretion, recombinant microorganisms for their production, and synthetic fibers (including advantageously, microfibers) comprising these proteins that recapitulate many properties of natural silk. The recombinant microorganisms can be used for the commercial production of silk-like fibers.
US10435515B2
One of the purposes of the present invention is to provide a polysiloxane macromonomer which has high hydrophilicity and a narrow molecular weight distribution and is usable as a material for ophthalmic lenses. The present invention provides a both-terminal modified polysiloxane macromonomer represented by the following average structural formula [I′]: R′Me2SiO(Me2SiO)pSiMe2R′ [I′] wherein R′ represents —C3H6O(C2H4O)qC(═O)NH(C2H4O)rC(═O)C(Q)═CH2, Me is a methyl group, p is an integer of from 40 to 100, q is an integer of from 5 to 10, r is an integer of from 2 to 3 and Q is a methyl group or a hydrogen atom. The both-terminal modified polysiloxane macromonomer according to claim 1, having a molecular weight distribution, Mw/Mn, of 1.3 or less.
US10435504B2
Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described.
US10435503B2
A process comprising, consisting of, or consisting essentially of: foaming a reaction mixture containing at least one polyisocyanate and an isocyanate-reactive compound comprising at least one alkoxylated triazine-arylhydroxy-aldehyde condensate composition wherein the alkoxylated triazine-arylhydroxy-aldehyde condensate composition is a reaction product of a triazine-arylhydroxy-aldehyde condensate and at least one alkylene carbonate, is disclosed.
US10435493B2
A multimodal polyethylene copolymer suitable for use in cable insulation comprising: (III) 45 to 55 wt % of a lower molecular weight component which is an ethylene copolymer of ethylene and at least one C3-12 alpha olefin comonomer, said LMW component having a density of 940 to 962 kg/m3 and an MFR2 of 50 to 500 g/10 min; (IV) 55 to 45 wt % of a higher molecular weight ethylene copolymer component of ethylene and at least one C3-12 alpha olefin comonomer; wherein said multimodal polyethylene copolymer has a density of 940 to 950 kg/m3, an MFR2 of 0.05 to 2.0 g/10 min and preferably at least one of crystallization half time>3.0 mins at 120.5° C., a crystallization half time>5.0 mins at 121° C. or a crystallization half time>10.0 mins at 122° C.
US10435492B2
Catalyst systems having both a metallocene catalyst component and a Ziegler-Natta component are disclosed. Such catalyst systems can contain a metallocene compound, an activator-support, an organoaluminum compound, and a Ziegler-Natta component comprising titanium supported on magnesium chloride.
US10435489B2
Ethylene-based polymer is made by a process comprising polymerizing a reaction mixture comprising ethylene and at least one chain transfer agent system; wherein the polymerization takes place in the presence of at least one free-radical initiator; and wherein the polymerization takes place in a reactor configuration comprising at least one tubular reactor with at least three reaction zones; and wherein at least two reaction zones receive an ethylene feed; and wherein the degree of polymerization in the first reaction zone is less than, or equal to, (5/LCBf)*3150; and wherein the ethylene-based polymer formed by the process comprises the following properties: (A) LCBf≥(4.7+0.5*log(I2)); and (B) I2 from 0.2 to 25 dg/min.
US10435482B2
Methods of improving the re-dispersibility of dried or at least partially dried microfibrillated cellulose, methods of re-dispersing dried or at least partially dried microfibrillated cellulose, compositions comprising re-dispersed microfibrillated cellulose and the use of re-dispersed microfibrillated cellulose in an article, product or composition; and methods of improving the physical and/or mechanical properties of re-dispersed dried or partially dried microfibrillated cellulose.
US10435478B2
Disclosed is an antibody or a binding fragment thereof which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody or the fragment thereof can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone in a single lateral flow assay device.
US10435476B2
There is disclosed compositions and methods relating to or derived from anti-JAG1 antibodies. More specifically, there is disclosed fully human antibodies that bind JAG1, JAG1-binding fragments and derivatives of such antibodies, and JAG1-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having JAG1 related disorders or conditions. There is also disclosed a method for treating JAG1-expressing tumors, including hepatocellular carcinomas and squamous carcinomas, and non-oncology diseases selected from the group consisting of rheumatoid arthritis, experimental lung injury, atherosclerosis, chronic liver disease induced by hepatitis C virus, ischemic myocardial injury and heart failure.
US10435471B2
The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
US10435470B2
The present disclosure relates to antibodies and antigen-binding fragments thereof that bind to PD-L1, and to methods of using such antibodies and antigen-binding fragments. For example, the present invention provides humanized anti-PD-L1 antibodies and methods of use thereof.
US10435469B2
Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.
US10435468B2
Disclosed are antibodies, including antibody drug conjugates, that specifically bind to NTB-A. Also disclosed are methods for using the anti-NTB-A antibodies to detect or modulate activity of (e.g., inhibit proliferation of) an NTB-A-expressing cell, as well as for diagnoses or treatment of diseases or disorders (e.g., cancer) associated with NTB-A-expressing cells. Further disclosed is a method of treating multiple myeloma using an anti-NTB-A antibody drug conjugate, which optionally includes an anti-NTB-A antibody as disclosed herein.
US10435466B2
Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer or infectious disease or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with a preferred embodiment of a bispecific antibody against TIM-3 and CD3.
US10435461B2
The present invention addresses a need for improved treatments for filovirus infections. This invention provides an isolated humanized anti-filovirus glycoprotein pre-fusion core antibody comprising a framework region having a sequence of 95% or greater identity to a human antibody framework region. Also provided is a method of treating and/or inhibiting a filovirus infection in a subject comprising administering to the subject an amount of any of the antibodies described herein, or an amount of an antigen-binding fragment thereof. Also provided is composition comprising any of the antibodies described herein, or or an amount of an antigen-binding fragment thereof. In an embodiment, the composition comprises a pharmaceutically acceptably carrier.
US10435459B2
The present invention relates to a pharmaceutical composition for the prevention or treatment of non-alcoholic fatty liver disease including a long-acting GLP-1/glucagon receptor dual agonist, and a method for preventing or treatment of non-alcoholic fatty liver disease including administering the composition. The composition of the present invention either has no side effect of weight gain or reduces the side effect of weight gain, which is a side-effect of conventional therapeutic agents for non-alcoholic fatty liver disease, and reduces the amount of administrations of a long-acting GLP-1/glucagon receptor dual agonist, thus greatly improving patient's convenience. In addition, the long-acting GLP-1/glucagon receptor dual agonist of the present invention improves in vivo sustainability and stability.
US10435454B2
A method of treating a patient who has melanoma includes administering to said patient a composition containing a population of activated T cells that selectively recognize cells in the patient that aberrantly express a peptide. A pharmaceutical composition contains activated T cells that selectively recognize cells in a patient that aberrantly express a peptide, and a pharmaceutically acceptable carrier, in which the T cells bind to the peptide in a complex with an MHC class I molecule, and the composition is for treating the patient who has melanoma. A method of treating a patient who has melanoma includes administering to said patient a composition comprising a peptide in the form of a pharmaceutically acceptable salt, thereby inducing a T-cell response to the melanoma.
US10435445B2
The present invention provides a novel peptide compound having an activating action on GIP receptors and use of the peptide compound as a medicament.Specifically, a peptide containing a sequence represented by the formula (I) or a salt thereof and a medicament comprising the same are provided. (I) P1-Tyr-A2-Glu-Gly-Thr-A6-A7-A8-A9-A10-A11-A12-A13- A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-A25- A26-A27-A28-A29-A30-A31-A32-A33-A34-A35-A36-A37- A38-A39-A40-P2 wherein each symbol is as defined herein.
US10435444B2
An object of the invention is to provide an agent for preventing or treating corneal disorders, such as corneal epithelial disorder, dry eye, and reduction in corneal sensitivity. This object is achieved by using angiopoietin-like protein 7 as an active ingredient.
US10435440B2
The present invention relates to a chimeric nucleotide sequence encoding peptides with antimicrobial activity, to be expressed on plants as bioreactors, plant cell or transformed plant material and E. coli, where plants and bacteria were used for scale-up production of antimicrobial peptide and that produces the peptide sequence derived from nucleotide sequence SEQ ID No. 1, SEQ ID No. 6 and SEQ ID No. 12. It includes a method for obtaining the amino acids sequence SEQ ID No. 9 derived from a chimeric nucleotide sequence which encodes to antimicrobial peptides, wherein said amino acids sequence is derived from the synthetic DNA sequence SEQ ID No. 1, obtained from a back-translation of the amino acid sequence of the peptide Ap-S of Argopecten purpuratus scallop.
US10435434B2
Deuterated compounds, compositions, and methods for treating cancers associated with ETBR activation
Disclosed herein are deuterated compounds, pharmaceutical compositions thereof, and methods for treating ETBR-related cancers. Also disclosed herein is a delivery system for the controlled, systemic release of at least one deuterated ETBR antagonist, optionally in conjunction with an additional anti-oncologic agent.
US10435432B2
The invention provides a one-step process for preparing a cell-binding agent cytotoxic agent conjugate comprising contacting a cell-binding agent with a cytotoxic agent to form a first mixture comprising the cell-binding agent and the cytotoxic agent and contacting the first mixture comprising the cell-binding agent and the cytotoxic agent with a bifunctional crosslinking reagent, which provides a linker, in a solution having a pH of about 4 to about 9 to provide a second mixture comprising the cell-binding agent cytotoxic agent conjugate, wherein the cell-binding agent is chemically coupled through the linker to the cytotoxic agent, free cytotoxic agent, and reaction by-products. The second mixture is then optionally subjected to purification to provide a purified cell-binding agent cytotoxic agent conjugate.
US10435425B1
Disclosed herein a sialyl donor and its use for the synthesis of gangliosides. The sialyl donor has the structure of, wherein, R1 and R2 are independently benzoyl, toluenesulfonyl, pivaloyl or acetyl optionally substituted with a halogen; and R3 is acetyl or —(O)CCH2OH. In one preferred embodiment, in the sialyl donor of formula (I), R is acetyl. Also disclosed herein is a method of synthesizing a sialoside. The method comprises steps of: coupling the sialyl donor of formula (I) with a glycosyl acceptor having a primary hydroxyl group in the presence of N-iodosuccinimide (NIS) and trifluoromethanesulfonic acid (TfOH) under suitable conditions; and isolating the sialoside, which has an α-glycosidic linkage. According to preferred embodiments, the coupling is conducted in a solvent selected from the group consisting of, CH3CN, CH3Cl, and CH2Cl2 at a temperature between −20° C. to −60° C. Additionally or optionally, the coupling is conducted in CH2Cl2 with the presence of a powdered molecular sieve at −40° C.
US10435423B2
Provided herein are functionalized phosphonates and methods for making same via phosphite addition to an atom alpha to an electron withdrawing group. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US10435415B2
Disclosed are compounds of Formula (I) wherein: the two dotted lines represent either two single or two double bonds; Q is: R1 is F, Cl, —CN, or —CH3; R2 is Cl or —CH3; R3 is —C(CH3)2OH or —CH2CH2OH; Ra is H or —CH3; each Rb is independently F, Cl, —CH3, and/or —OCH3; and n is zero, 1, or 2. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
US10435403B2
The present application relates to positive allosteric modulators of the muscarinic M2 receptor, especially to novel 7-substituted 1-arylnaphthyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of cardiovascular disorders and/or renal disorders.
US10435397B2
The present invention relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinase, such as aminopyrazine-isoxazole derivatives and related molecules. The present invention also relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I or II:
US10435393B2
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
US10435386B2
A novel process is provided for the efficient preparation of an asymmetric compound of structural formula I: comprising a copper-catalyzed, carbon-nitrogen cross-coupling step. The process described as part of the present invention can be used to manufacture poly (ADP-ribose) polymerase (PARP) inhibitors, which may be useful for the treatment of cancer. In particular, the present invention describes a process for the manufacture of the PARP inhibitor, 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide.
US10435383B2
The present invention can provide novel C-glycoside derivatives which are biologically important under high stereoselective, mild, atom economical condition.
US10435376B2
Disclosed are derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs. The derivatives have structural formulae as shown in formulae (I) to (VI). The derivatives of 1H-imidazole-4,5-dicarboxamide as disclosed in the present invention have significant anticoccidial effect, especially against coccidia that show a resistance to other anticoccidial drugs, and thus they can be used in preparation of anticoccidial drug.
US10435368B2
High heat monomer compounds, methods for preparing compounds, and compositions derived from the compounds are provided. Also provided are materials and articles derived from the compounds.
US10435364B2
A compound of formula (1), (1′), (1″) or (1′″) or a pharmaceutically acceptable salt thereof, for use in the treatment of diseases or conditions for which a bromodomain inhibitor is indicated.
US10435362B2
One exemplary embodiment can be a process for oxidizing one or more thiol compounds from an alkaline stream. The process may include passing a mixed stream having the alkaline stream to a vessel having an oxidation section, a separation section and a vent gas section. Often, the oxidation section includes a body containing one or more packing elements. The process can further include passing an oxidized alkaline stream to the separation section containing a first chamber and a second chamber. Usually, the first chamber contains a coated mesh and packing. The two sections further form a neck contains a packing, a distributor, and a mesh.
US10435356B1
A composition is disclosed that includes a Nitrate or a Nitrite of an Amino Acid Compound selected from the group consisting of Arginine, Agmatine, Beta Alanine, Citrulline, Creatine, Glutamine, L-Histidine, Isoleucine, Leucine, Norvaline, Ornithine, Valine, Aspartic Acid, Cysteine, Glycine, Lysine, Methionine, Proline, Tyrosine, and Phenylalanine, wherein the composition is formulated to deliver an effective amount of the Nitrate or Nitrite of the Amino Acid Compound to prevent the development of nitrate tolerances, to increase bioabsorption of amino acids, to increase the vasodilative characteristics of amino acids, or to increase athletic performance in a human or animal. The composition may be in a dosage form selected from the group consisting of a capsule, a cachet, a pill, a tablet, a powder, a granule, a pellet, a bead, a particle, a troche, a lozenge, a gel, a liquid, a suspension, a solution, an elixir, and a syrup.
US10435352B2
A process for preparing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids of the formula (I) is described. Here, the substituents are radicals such as alkyl and substituted phenyl.
US10435350B2
A compound is represented by the following formula (1). In the formula (1), Ar is a substituted or unsubstituted aryl group including 6 to 30 ring carbon atoms, Ra are independently a substituted or unsubstituted alkyl group including 1 to 15 carbon atoms, or a substituted or unsubstituted cycloalkyl group including 3 to 15 carbon atoms, Rb1 to Rb4 are independently a halogen atom, a cyano group, a substituted or unsubstituted alkyl group including 1 to 15 carbon atoms, or the like, Rc1 to Rc10 are independently a hydrogen atom, a halogen atom, a cyano group, a substituted or unsubstituted alkyl group including 1 to 15 carbon atoms, or the like, * is a bonding position at which one of Rc1 to Rc10 is bonded to either nitrogen atom, x is an integer from 0 to 3, y is an integer from 0 to 4, and z are independently an integer from 0 to 5.
US10435349B2
A process for preparing a variety of secondary and tertiary alkyl formate esters via the coupling of methanol and secondary (or tertiary) alcohols. Iron-based catalysts, supported by pincer ligands, are employed to produce these formate esters in high yields and unprecedentedly high selectivities (>99%). Remarkably, the coupling strategy is also applicable to bulkier tertiary alcohols, which afford corresponding tertiary formate esters in moderately high yields and high selectivities.
US10435346B2
A process for the distillation of an aldehyde mixture comprising a straight-chain aldehyde and a branched-chain aldehyde is described in which the process comprises: supplying a feed comprising the aldehyde mixture to a first separation vessel; operating said first separation vessel at a first temperature and a first pressure such that separation occurs; recovering a first stream comprising the straight-chain aldehyde from said first separation vessel and supplying said first stream to a second separation vessel; operating said second separation vessel at a second temperature and a second pressure such that separation occurs; recovering a product stream comprising the straight-chain aldehyde and a second stream comprising high-boiling components from said second separation vessel, and supplying said second stream to a third separation vessel; operating said third separation vessel at a third temperature and a third pressure such that separation occurs; and recovering a third stream comprising the aldehyde mixture from said third separation vessel and reintroducing said third stream to the first separation vessel.
US10435340B2
A process for the distillative separation of ethylbenzene from a mixture comprising ethylbenzene and at least one other C8 aromatic compound, comprising introducing a feed stream comprising said mixture into a first distillation column, introducing a first stream comprising a heavy solvent above the feed stream into the first distillation column, introducing an aqueous stream below the feed stream into the first distillation column.
US10435338B2
A gaseous fraction leaving overhead from a fractionation column of a catalytic cracking unit (FCC) is fractionated using a unit for the conversion of ethylene into propylene, in order to upgrade the ethylene contained in the fuel gas.
US10435324B2
A system and method for making an edge section of a thin, high purity fused silica glass sheet. The method includes a step of directing a laser to melt through the glass sheet with localized heating of a narrow portion of the glass sheet to form an edge section of the glass sheet, and continuing the edge section to form a closed loop defining a perimeter of the glass sheet. The method further includes rapidly cooling the glass sheet through the glass transition temperature as the melted glass of the edge section contracts and/or solidifies to form an unrefined-bullnose shape extending between first and second major surfaces of the glass sheet.
US10435321B2
The present invention provides a stirrer for manufacturing glass including a stirrer shaft and a multi-staged rod-shaped stirrer blade fixed so as to penetrate through the stirrer shaft. This stirrer blade is a hollow cylindrical body including: a cylinder obtained by seam welding of two opposing sides of a flat plate made, for example, from strengthened platinum containing platinum or a platinum alloy as a matrix and metallic oxide dispersed in the plate; and a disk welded to an entire circumference of both ends of the cylinder and made from an identical material, and it penetrates so that a weld line crosses a center axis of the stirrer shaft, and is fixed so that a locus of an end portion of the blade forms a spiral shape. In addition, the rod-shaped stirrer blade has a core layer showing a dispersed structure that exists in a cross-sectional structure at a fixing portion with the stirrer shaft and does not receive heat effect resulting from fixing. The present invention is effective in stirring of molten glass having high viscosity, and has enhanced stirring operation and improved durability against deformation and damage.
US10435319B1
Control over the wastewater purification can be achieved through controlling delivery of gas-dispersion return sludge solely to an aerobic reaction vessel. The gas-dispersion return sludge is created using pure oxygen or oxygen containing trace amounts of ozone as a reactive gas, which is blended with return sludge to create a mixture of gas and liquid, which is pressurized with an atomizer pump, and then at a pressure of not more than approximately 5.5 MPa, the mixture is passed through an atomizer which uses cavitation or ultrasound at a frequency of less than 12,000 KHz to instantly render the reactive gas in the mixture to an ultra-fine bubble state. A portion of the gas is placed into a dissolved state, reaching a state of supersaturation with a high DO value of 20-40 mg/l, and causing the remaining ultra-fine bubbles to create an ultra-fine bubble condition.
US10435317B2
Metal-free materials, manufacturing thereof, method using thereof for (in-situ or ex-situ) catalytically treating contaminated soil or waters, including remediation of groundwater contaminated by haloalkenes, haloalkanes, nitro-compounds, and nitrophenol using sulfide as a reductant. Metal-free materials are manufactured with industrial scrap syrup or biomass. Method using the metal-free materials for in-situ treatment consists with the processes of adding materials into the contaminated medium, introducing sulfide into the contaminated medium, and reductive reacting contaminants with sulfide catalyzed by the metal-free materials. Specially, the formation of in-situ reaction zone is the key point of in situ treatment by retaining the catalyst in the contaminated medium. Method using the metal-free materials for ex-situ treatment consists steps of adding materials and sulfide into the contaminated fluid, intermingling the contaminated fluid with materials in a vessel, reacting contaminants with sulfide catalyzed by the metal-free material.
US10435307B2
A closed loop contaminant control system for an evaporative water purification process at an oil recovery facility includes an evaporator having a water inlet, a distilled water discharge, and an oil and brine water discharge. A sump in the evaporator is divided by an oil skimming weir into a main sump and a blowdown sump, with the oil and brine water discharge located proximate the blowdown sump and the steam discharge located above the oil and brine discharge. A distillate tank receives distilled water from the evaporator and discharges the distilled water. The distillate tank has a level controller, other controllers provided for the system include a distilled water flow meter, a blowdown flow meter, a cycle controller, a total flow controller, a hardness controller, and a silica controller.
US10435305B2
Provided is a producing method that makes it possible to stably manufacture a homogeneous titania monolithic porous body by a sol-gel method using various titanium alkoxides as a titanium precursor. The method comprises the steps of; preparing a titanium precursor solution by mixing a titanium alkoxide other than titanium methoxide, which is a titanium precursor, and a first anion source in an organic solvent; preparing a sol by adding water or an aqueous solution containing a second anion source to the titanium precursor solution; forming a co-continuous structure of a titania hydrogel phase and a solvent phase by subjecting the sol to sol-gel transition and phase separation in parallel; and removing the solvent phase from the co-continuous structure, in which a temperature lower than the boiling point of the compound having the lowest boiling point present in the titanium precursor solution is maintained in the first three steps, and in which a blending amount of the first anion source or that of the first and the second anion sources is set such that a molar ratio of the first anion source or a molar ratio of the first and the second anion sources in total to the titanium precursor is equal to or higher than 1.05.
US10435304B2
A process for production of ammonia includes: providing a reaction stream including carbon monoxide and hydrogen; passing the reaction stream and steam over a water gas shift catalyst in a catalytic shift reactor, forming a shifted gas mixture depleted in carbon monoxide and enriched in hydrogen; passing the shifted gas mixture with an oxygen-containing gas over a selective oxidation catalyst at ≥175° C., forming a selectively oxidized gas stream with a portion of the carbon monoxide converted to carbon dioxide; removing some of the carbon dioxide from the selectively oxidized gas stream in a carbon dioxide removal unit; passing the carbon dioxide depleted stream over a methanation catalyst in a methanator to form a methanated gas stream, optionally adjusting its hydrogen:nitrogen molar ratio to form an ammonia synthesis gas; and passing the ammonia synthesis gas over an ammonia synthesis catalyst in an ammonia converter to form ammonia.
US10435296B2
Provided is a liquid hydrogen storage material including 1,1′-biphenyl and 1,1′-methylenedibenzene, the liquid hydrogen storage material including the corresponding 1,1′-biphenyl and 1,1′-methylenedibenzene at a weight ratio of 1:1 to 1:2.5. The corresponding liquid hydrogen storage material has excellent hydrogen storage capacity value by including materials having high hydrogen storage capacity, and is supplied in a liquid state, and as a result, it is possible to minimize initial investment costs and the like required when the corresponding liquid hydrogen storage material is used as a hydrogen storage material in a variety of industries.
US10435293B2
Formation of a boron nitride nanotube nanocomposite film by combining a boron nitride nanotube solution with a matrix such as a polymer or a ceramic to form a boron nitride nanotube/polyimide mixture and synthesizing a boron nitride nanotube/polyimide nanocomposite film as an electroactive layer.
US10435284B1
A load laser guidance system for a forklift having a pair of laterally overlapping and laterally adjustable hollow parallelepiped bars on a forklift front end. A pair of servo motors, provided for the lateral adjustment of the bars, is disposed within the bars, which are attached to the mast assembly by a pair of braces. Forwardly projecting laser sensors, disposed on each bar, are configured to detect a width of a load of palletized cargo and to then communicate with a central processing unit within an interior dashboard which, in turn, activates servo motors to adjust the width of the bars to determine if the cargo can fit within a particular storage space. A dashboard monitor on the dashboard includes controls and a monitor screen permitting manual override of bar width adjustment. Weight sensors, disposed on each forklift arm, recognize load presence prior to activation of the laser sensors.
US10435283B1
A turntable leveling system is configured to level a boom turret of an aerial device. This allows the boom turret to be leveled more than with level correction by outriggers. The turntable leveling system includes a lower turntable wedge and an upper turntable wedge. Each of the lower turntable wedge and the upper turntable wedge is independently rotatable relative to the chassis. The turntable leveling system is configured to be installed between a chassis and the boom turret of an aerial device. The turntable leveling system may further comprise a central turntable wedge disposed between the upper turntable wedge and the lower turntable wedge.
US10435281B1
A Multi-Armed Lifting Accessory is disclosed herein which is compact and transportable in various deployments. The Multi-Armed Lifting Accessory is advantageous and useful as it has hingedly connected loading and support arms attached to a main lifter body. The supporting arms are spring loaded allowing the Multi-Armed Lifting Accessory to stably engage with irregular shaped objects such as barge lid or a skidsteer loader and allows for flexible engagement and balanced lifting operations.
US10435280B2
A lift truck can include a mast and a lift cylinder. The lift cylinder can include a piston rod and a cylinder housing. The lift truck also can include a piston rod retention mechanism that restricts movement of the lift cylinder in a direction lateral to an axial direction when the mast is in an extended position.
US10435279B2
System, method, and apparatus for providing route guidance to a customer in a shopping facility space are provided. A system for providing route guidance comprises a communication device configured to communicate with a user interface device, a store map database storing location information for a plurality of items available for purchase in the retail space, and a control circuit coupled to the communication device and the store map database. The control circuit is configured to receive a list of items for purchase from a user associated with the user interface device via the communication device, retrieve location information associated with each item of the list of items for purchase from the store map database, determine a route based on at least one user entered route preference and the location information associated with each item of the list of items for purchase, and provide the route to the user interface device.
US10435274B2
A container for maintenance capsule as a component of a maintenance system for an offshore wind turbine maintenance program. The container transports tools, parts and maintenance personnel to and from respective wind turbine towers. The container is seaworthy, watertight and floatable, and can be loaded on a maintenance vessel which carries the container to and from a wind turbine tower.
US10435272B2
The present invention provides an elevator-calling control apparatus, an elevator-calling control system and an elevator-calling control method thereof, and belongs to the field of elevator control technologies. In an elevator-calling control process, the following steps are included: inputting an elevator-calling command; displaying elevator running state information and estimated time of arrival information of several elevators in a corresponding elevator group for a passenger to make reference, wherein the elevator running state information at least includes information that reflects a current crowding degree of the elevator; and selecting an elevator from the several elevators as the elevator that the passenger determines to take. The elevator-calling control of the present invention may facilitate a passenger to actively select an elevator that the passenger determines to take, which has good user elevator calling and taking experience and enhances the running efficiency of the elevator.
US10435268B2
Implementations of a tape holder are provided. In some implementations, the tape holder may be used to secure a roll of tape to a magnetic surface. In some implementations, the tape holder is comprised of a base member and a spool support. In some implementations, the base member has one or more magnets on one side for securing the tape holder to a surface. In some implementations, the spool support is configured to secure a roll of tape to the tape holder. In some implementations, the spool support is configured to receive a roll of tape thereon. In some implementations, the spool support may include one or more flexible members thereon configured to releasably secure a roll of tape on the spool support. In some implementations, the tape holder may include a bearing shelf. In some implementations, the bearing shelf may be configured to support a roll of tape thereon.
US10435266B2
An automatic mesh reeling machine includes a manual fiber loading mesh disc mechanism, a quantitative fiber mesh conveying mechanism, a fiber mesh cutting mechanism, an automatic mesh reeling mechanism of left and right mesh reeling hands, an automatic fiber mesh drum delivery mechanism and an automatic mesh stapling mechanism of a mesh stapler. Information about replacing a mesh disc can be transmitted under the cooperation of a mesh pressing rod and a micro switch. A servo motor drives a metering roll to realize fixed length feeding of a mesh. A cutter cylinder drives a blade to cut the fixed length mesh. A left mesh reeling hand and a right mesh reeling hand reel the mesh into a closed mesh drum. A sliding table cylinder, pneumatic parallel clamping jaws and an electric servo cylinder move the fiber mesh drum to a specified position.
US10435258B2
A sheet conveyance apparatus includes a storage unit storing a sheet, a conveyance member to convey a sheet, a support shaft portion, and a separation unit. The support shaft portion has one end fixed to a main body of the sheet conveyance apparatus and the other end as a free end that is not fixed to the main body. The separation unit pinches and conveys a sheet with the conveyance member and separates a plurality of sheets stored in and fed from the storage unit one by one. The separation unit includes a separation member that is supported by the support shaft portion and rotatable with the support shaft portion, and a holding member to hold the separation member. By moving the holding member in an axial direction of the support shaft portion, the separation unit is removed from the apparatus with the holding member holding the separation member.
US10435248B2
The invention relates to a reciprocating slat conveyor multiple parallel slats that are slidable in the longitudinal direction, wherein the slats comprise subsequently alternating a first slat and a second slat, wherein the first slats comprise a horizontal upper wall section and an upright end wall section, and wherein the second slats comprise a horizontal upper wall section and a vertically upright wall section, wherein the upright wall section outwardly merges into an overhanging wall section that extends over the end wall section of the adjacent first slat, wherein the overhanging wall section merges into a vertically downwardly pending end wall section that extends aside the end wall section of the adjacent first slat, wherein a seal is present between the upright wall section and the end wall section of the second slat.
US10435244B2
A conveyor includes a powered pop-up roller driven by separable drive components. A first drive component is rigidly coupled to the frame of the conveyor. The first drive component induces motion driving the roller in a second drive component, which is fixed to the roller but separable from the first drive component.
US10435241B2
A system and method for storage and retrieval are provided. The system includes a multi-level storage structure, and mobile robots configured to pick, transport and place one or more tote, container, or object. This system and method can be used in order-fulfillment applications in which one or more workstations accommodate a picker that transports one or more eaches from a tote on one of the autonomous mobile robots to a put location, and an input/output interface induct material into the system and discharge fulfilled orders from the system. The mobile robots are further configured to move from level to level in the multi-level storage structure via inclined or vertical tracks without requiring a vertical lift or vertical conveyor.
US10435232B2
A cooperative packaging system includes a base package, a first member, a second member, and a third member. The base package includes a first side and a second side. The second side is contiguous with the first side. The first member covers a portion of the first side of the base package. The second member covers the second side of the base package. The third member covers the first member and a portion of the second member. The first member and the second member are configured to mitigate impacts sustained by the cooperative packaging system prior to the impacts being transferred to the base package.
US10435215B2
A metal decorative product has a metallic luster decoration coated packaging on at least one side of a substrate and encloses a part disposed with electromagnetic wave device. The metallic luster decoration coated packaging is formed by coating an ink mixed with metal powder. In the metallic luster decoration coated packaging, the ink is used to make the metal powder and metal powder connection formed by the metal powder insulated and independent from each other.
US10435208B2
An improved closure adapted for use with a suitably configured dispensing container the closure comprising as parts of a single sidewall; a compressible main body part having a sidewall having disposed thereon and/or formed within one or more gripping means, a set of mating threads upon the interior of the sidewall, and a base edge, a distensible base skirt part which depends from the main body part by connecting cowling sections, the base skirt part comprising sidewall rim regions which are connected to the cowling sections but separated from the main body part by arcuate perforations in the region between the cowling sections and a base edge of the main body part, and further a catch pawl present within the cowling section. The closure provides for controlled removal of the closure from the dispensing container.
US10435204B2
A plastic container capable of assuming a loading state, an initially sealed state and an opened state comprises a lid including a lid rim and a base having a base rim. The lid rim sealingly engages with the base rim. A projecting portion has an accordiated section and a pull tab that projects outwardly from the lid. The accordiated section has at least one pleat. The projecting portion includes a frangible bridge. When the plastic food container is in the initially sealed state, the accordiated section has a first length and a first orientation relative to the projecting portion. When the container is in the initially sealed state and a first pulling force is applied to the pull tab, the frangible bridge ruptures. When the frangible bridge ruptures and before the lid is separated from the base, the container is in a tab-employed state in which the accordiated section springs outward and has a second length visibly longer than the first length.
US10435201B2
The present invention provides a packaging assembly for packaging one or more articles, comprising: an inner body part which defines at least one inner compartment to receive an article; an outer body part that at least partially encompasses the inner body part; and a cover member which is movable between a closed position to prevent access to the at least one inner compartment and an open position to permit access to the at least one inner compartment; wherein the outer body part is movable relative to the inner body part between a first position and a second position to move the cover member between the closed position and the open position.
US10435200B2
A storage system, comprising a body having a cavity therein configured to house one or more items, and an opening defined by the body and a panel configured to mate with the opening and prevent access to the cavity when the panel is in position; the system have a first level of security securing items stored in the cavity; a second level of security securing the body from a structure from which it is hung, and an third level of security disguising the storage system as a hanging piece of clothing.
US10435194B2
A reinforced box includes a body board comprising a bottom panel; a first side panel hingedly attached to the bottom panel, a first side flap hingedly attached to the first side panel; a second side panel hingedly attached to the bottom panel, a second side flap hingedly attached to the second side panel; and a first end flap and a second end flap each hingedly attached to the bottom panel, the first end flap adjacent to the second end flap; and an end panel, the first side flap of the first side panel attached to the end panel proximate to a first side of the end panel, the second side flap of the second side panel attached to the end panel proximate to a second side of the end panel, the first end flap and the second end flap attached to the end panel.
US10435190B2
A method for quality control of a packaging system is provided. The method comprises receiving a first record of packaging quality parameter data related to a first packaging quality parameter for a package being assessed, determining a second packaging quality parameter based on said first record, requesting a second record of packaging quality parameter data related to said second packaging quality parameter, and receiving said second record.
US10435178B2
A holding fixture includes a first blade support assembly and a second blade support assembly. The second blade support assembly is spaced at a distance from the first blade support assembly and includes a base plate removably mounted to a milling machine, an adjustable conic support connectable to the base plate via a spacer block, and a blade adjustment assembly movable to control a pressure applied by the blade adjustment assembly.
US10435172B2
A display device for displaying the attitude of an aircraft with respect to a fixed direction in space is described, said device comprising: a first element that can be fastened to the aircraft; and a second element, which is free to move with respect to the first element, following a change in position of first element with respect to the fixed direction; the second element in turn comprising: a mass, which is designed to return the second element to the same stable position with respect to the fixed direction when the first element changes its position with respect to the fixed direction; and a visual indication, which is representative of the position of the fixed direction, as the position of the first element changes.
US10435170B2
An example system includes a fuel tank, fittings mounted through a wall of the fuel tank, and optical sensors positioned within the fittings. A respective optical sensor includes a first pressure sensing end inserted through a fitting and internally into the fuel tank and a second end extending externally from the fuel tank. The system also includes an optical fiber bundle mounted external to the fuel tank, and having an optical fiber connected to each of the plurality of optical sensors for guiding light to each of the plurality of optical sensors.
US10435169B2
A vertical take-off aircraft with a propulsion drive for generating a driving force being effective in a horizontal direction and with a lift drive for generating a lifting force being effective in a vertical direction includes a motor for providing mechanical energy for the propulsion drive and a first generator for providing electrical energy for the lift drive. Moreover, the aircraft includes an exhaust gas turbocharger for the motor with a first turbine being driven by an exhaust gas flow of the motor, wherein the first turbine is configured to provide mechanical energy for the propulsion drive.
US10435164B2
The disclosure relates to a propeller drive that is, in particular, an aircraft drive and includes a propeller machine and an electric drive connected without a converter to the propeller machine. The aircraft includes such a propeller drive.
US10435163B2
An aircraft propelled by a turbojet having contrarotating fans, the turbojet being incorporated at the rear of a fuselage of the aircraft and in line therewith and including two gas generators that feed a working turbine having two contrarotating turbine rotors for driving two fans arranged downstream from the gas generators, and distinct air intakes for feeding each gas generator, the air intakes being connected to the fuselage of the aircraft so as to take in at least a portion of the boundary layer formed around the fuselage of the aircraft.
US10435161B1
Apparatus and associated methods relate to differentiating ice accretion caused by different supercooled water droplets on an airfoil of an aircraft. A sensor having a sensing surface region is mounted at a mounting location of the airfoil such that the sensing surface region is flush with a surrounding adjacent surface of the airfoil. Water particles of sizes less than or equal to a predetermined threshold do not impinge the sensor surface region at the mounting location when the aircraft is in flight. A sensor driver provides an excitation signal to the sensor. A signal detector detects a sensor signal responsive to the provided excitation signal. The sensor signal is indicative of water particles exceeding the predetermined threshold impinging the sensing surface region. In some embodiments, the sensing surface region is mechanically coupled to a resonant cavity. In other embodiments, the sensor is a surface resistance sensor configured to sense surface resistance.
US10435158B2
A aircraft passenger seating arrangement comprises a seat (1), a secondary surface (4) spaced to one side of the seat (1), in a direction substantially parallel to the width of the seat; and an infill surface (3) deployable into a space between the seat (1) and the secondary surface (4) so as to form a substantially continuous sleeping surface along the secondary surface (4), the infill surface (3) and the width of the seat (1).
US10435157B2
Described are headrests with integrated entertainment systems. The headrest includes a shell that is coupled to a seat through a headrest mount that has at least one degree of freedom of movement. The headrest shell also supports a visor with at least one side arm and a display span that may rotate between stowed and deployed positions. A neutral position mechanism supports the headrest in a neutral position and provides resistance to movement between the headrest and the passenger seat. The attachment of the visor to the headrest shell may also include an adjustment slot to allow fore and aft translation of the visor with respect to the headrest shell. The fore and aft translation of the visor allows for positioning the visor at different focal lengths, and provides extra clearance for the visor as it moves between stowed and deployed positions.
US10435156B2
An airworthy, unmanned transport apparatus (1) has a payload container (2) for at least one consignment (14), wherein the transport apparatus (1) has on its underside (4) at least two latching arms (5) which are arranged opposite one another and are each subjected to a spring force and by way of which the payload container (2) is able to be latched onto the transport apparatus (1) such that, as a result of the latching arms (5) being pressed in, the payload container (2) is releasable from the transport apparatus (1).
US10435155B2
A method to load stores on an aircraft, the method may be controlled by one or more controller and may include one or more acts of loading stores onto corresponding lift portions; determining a relative position of the aircraft; positioning the stores relative to the determined position of the aircraft; and securing the stores to corresponding hardpoints (HPs) of the aircraft.
US10435152B1
A hybrid cable configured to tether a drone or other aerial device to a base station may include at least one conductor configured to carry a power signal and at least one optical fiber component. A jacket may be formed around the at least one conductor and the at least one optical fiber component. The jacket may have an airfoil cross-sectional shape that is symmetrical about a center line extending from a first rounded edge to a second trailing edge. As a result, the cable may orient itself towards the wind and a lift force exerted on the cable may be approximately equal along opposite lateral sides of the cable.
US10435148B2
Disclosed is a system for controlling acoustic radiation from an aircraft. The system comprising a plurality of rotor systems (one or more) and a noise controller configured to regulate acoustic radiation from the plurality of rotor systems. The noise controller can be configured to regulate a commanded flight setting from the flight control system and to output a regulated flight setting to the plurality of rotor systems. Based on the regulated flight setting, the plurality of rotor systems are configured to generate, individually and in aggregate, acoustic radiation having a target acoustic behavior. The target acoustic behavior may be achieved using beamforming techniques to, for example, change the directionality of acoustic radiation from the plurality of rotor systems, or otherwise tune the acoustic radiation to reduce detectability and/or annoyance.
US10435147B2
A method for controlling each rotor on a multirotor aircraft includes receiving one or more sensed states of the multirotor aircraft, and determining a control scheme dynamically using the sensed one or more states of the multirotor aircraft. Receiving one or more sensed states can include receiving one or more of a rotational rate or acceleration of the aircraft, or any other suitable aircraft state.
US10435140B2
A system and method for blade angle position feedback. The system comprises an feedback device and a sensor mounted adjacent the feedback device and configured for detecting a passage of position markers on the feedback device during propeller rotation. The position markers are spaced apart from one another around the circumference of the feedback device and are oriented at an angle to one another and to a longitudinal axis. The feedback device and sensor are configured for relative axial displacement. A detection unit is connected to the sensor for receiving the sensor signal therefrom, determining on the basis of the sensor signal a time interval elapsed between the passage of successive position markers, and computing from the time interval blade angle position.
US10435139B2
A gurney flap arrangement comprises: an airfoil with an opening in a surface of the airfoil; a gurney flap having a first position in which at least a portion of the gurney flap extends through the opening and projects outwardly from the airfoil surface, and a second position in which the gurney flap does not project from the airfoil surface or projects outwardly from the airfoil surface to a lesser extent; and a seal disposed about the opening to seal a gap in the opening between the gurney flap and the airfoil.
US10435135B2
An apparatus and method that improves the operation of aerospace planes or rockets having an integrated flute and hat components whereby the flute functions as a hypersonic refrigeration engine and the hat as a flat plate heat exchanger to achieve an isothermal compression of the incipient hypersonic air in front of the nosecone to reduce hypersonic vibrations during flight, these improvements allow for the reduction in temperature during flight operation allowing for improved cooling of the aerospace plane or rocket.
US10435134B2
Core structures (120) for composite panels (75) of an aircraft (10), composite panels (75) and aircraft (10) including the core structures (120), and methods (200) of manufacturing the composite panels (75) are disclosed herein. The core structures (120) include a first side (140), a second side (150), and a connecting region (160) that interconnects an upper portion (142) of the first side (140) with an upper portion (152) of the second side (150). The first side (140), the second side (150), and the connecting region (160) at least partially define an antenna housing (62), which defines a housing volume (64) configured to contain an aircraft antenna (60) of the aircraft (10), and an electromagnetic wave transmission region (66) configured to permit electromagnetic waves to pass therethrough. The electromagnetic wave transmission region (66) defines a plurality of kite-shaped voids (130) arranged in a repeating pattern and bounded by a corresponding plurality of walls (170), at least 10% of which extends at least substantially perpendicular to a surface (122/124) that bounds the electromagnetic wave transmission region (66).
US10435133B2
A stringer for having a runout with a raised area configured to reduces stress while improving drainage across the runout when utilized in a close structural component of a vehicle such as an aileron of an aircraft. In one or more configurations, the raised area of the runout of the stringer includes multiple tapered surfaces adjacent to one another oriented and configured as ramps to collectively guide water up, over and down the raised area of the stringer.
US10435129B1
A watercraft comprising a compressed air propulsion system is shown and described. The watercraft includes at least one propeller operatively connected to an air motor. Storage tanks supply compressed air having a pressure of at least 2000 psi to a pressure regulator that reduces the pressure and supplies air to an air control valve. User controls adjust the air control valve to adjust the flow rate of air to the air motor which in turn adjusts the direction and/or speed of rotation of the propeller. An on-board air compressor energized by a plurality of lithium iron phosphate batteries provides air to the air storage tanks when the pressure falls below a specified value. In certain examples, the electric and air propulsion system is used to replace a fossil fuel engine in an existing watercraft and can remain at sea longer than the existing watercraft.
US10435122B2
Wakeboat propulsion apparatuses are provided that can include: a wakeboat having a hull; an engine mounted to the hull; a hydraulic pump driven by the engine; a hydraulic motor powered by the hydraulic pump; and a propeller powered by the hydraulic motor. Methods for propelling a wakeboat are also provided. The methods can include: engaging a hydraulic pump from a drive of an engine operationally mounted to a hull of the wakeboat; driving a hydraulic motor with hydraulic fluid received from the hydraulic pump; and operationally engaging a propeller using the hydraulic motor.
US10435121B2
A fin box is provided for detachably attaching a fin to a surfboard. The surfboard has a nose and a tail at opposite ends. The fin has a groove base with one or more pins. The fin box includes one or more inner walls. The inner walls have (i) a hollow base with a width that is at least as great as a width of the groove base and a length that is at least as great as a length of the groove base, (ii) one or more recess parts disposed at locations that correspond to the locations of the pins of the fin, the recess parts extending in a direction that is substantially perpendicular to a length of the fin box, and (iii) one or more ditch parts that extend from the recess parts, the ditch parts extending in a direction that is substantially parallel to the length of the fin box and toward the tail of the surfboard. The recess parts and ditch parts are configured to allow the fin to be inserted into the fin box by (i) pressing the fin downward into the fin box until a bottom of the groove base is adjacent to the hollow base, and (ii) sliding the fin toward the tail of the surfboard, without any opposite motion toward the nose of the surfboard. The ditch parts are configured to, when the fin is attached to the fin box, hold the pins of the fin in the fin box.
US10435109B2
A gasoline engine boosting system including a fuel tank, an engine, a fuel tube, an accelerator line, a drive sprocket, a drive chain, a discharge pipe and a fixing bracket. The fixing bracket includes an adjustable engine fixing bracket. The adjustable engine fixing bracket includes a first front fixing rod, a second front fixing rod, a first rear fixing rod, a second rear fixing rod, a front fixing base, a rear fixing base, a first tube clip and a second tube clip, the front fixing base and the rear fixing base are respectively fixed on a front side and a rear side of the engine. The front fixing base includes a front sliding adjustment groove. The rear fixing base includes a rear sliding adjustment groove allow. The gasoline engine boosting system is adaptable to a bicycle frame.
US10435107B2
A two wheeled vehicle is propelled by the feet of a rider and hand-grasped poles when pushing against the ground. A forward wheel on a forward member and a rear wheel on a rearward member align along a longitudinal axis. The forward member rotates about a vertical steering axis. A saddle supports the rider. A torso brace allows the rider to balance and steer the device.
US10435100B2
A bicycle component is provided with a base including a recess, a cover, a protected member that is at least partially arranged in the recess, and an engagement portion. The cover is configured to close the recess. The protected member is at least partially arranged in the recess. The engagement portion is configured separately from the cover and the protected member. The engagement portion is arranged in the recess and engages the cover that covers the recess.
US10435097B2
A bicycle seat has a bicycle saddle with a forward end and a rearward end, the saddle having an ischial region. One or more cushioning pads are placed on the saddle in the ischial region. The cushioning pads have an upper surface, with the cushioning pads being connected to the saddle in a manner that enables the upper surface of the cushioning pads to move either from side to side with respect to the saddle during pedaling, or forward and rearward with respect to the saddle during pedaling, or both from side to side and forward and rearward during pedaling.
US10435088B2
Disclosed herein are embodiments of a reinforcement or brace that can be installed on the tailgate of a vehicle. The reinforcement can provide structural support for heavier mounted objects, such as tires, as well as allowing for different attachment points. Advantageously, the tailgate hinge does not need to be removed or replaced.
US10435078B2
A system for controlling airflow through a syphon tube associated with a vehicle cowl airbox disposed within an engine compartment associated with a vehicle may include a drain valve disposed on one of a first open end and a second open end associated with a hollow tubular portion of the syphon tube. The drain valve may include a connecting portion configured to be received by a portion of a first passageway defined by a divider extending between the first open end and the second open end. The drain valve may further include a flap attached to the connecting portion, the flap configured to, in response to the vehicle cowl airbox being drained through a second passageway defined by the divider, allow air to flow through the first passageway and, in response to a negative pressure within the vehicle cowl airbox, prevent air from being drawn into the syphon tube.
US10435073B2
The disclosure relates to a method for operating a steering system of a motor vehicle having a power steering system. A support torque is introduced into a steering transmission. A driving situation is determined. The support torque is reduced depending on the driving situation.
US10435068B2
A suspension system for a vehicle may include a knuckle rotatably supporting a wheel and a plurality of arms connecting the knuckle with a vehicle body wherein an arm among the plurality of arms may be a virtual link formed by a virtual link module and a point at which the virtual link applies a constraint force to the knuckle may be formed at a virtual space.
US10435063B2
A method for detecting steering misalignments in an adaptive steering system of a motor vehicle, wherein the adaptive steering system has a steering wheel angle sensor for detecting a value representative of a steering wheel angle, an adaptive angle unit for detecting a value representative of an adaptive angle, and a wheel angle detection unit for detecting a value representative of a wheel angle. The method including detecting a value representative of the steering wheel angle, detecting a value representative of the adaptive angle, detecting or determining a value representative of the wheel angle, and computing a comparison value.
US10435058B2
A child stroller apparatus includes a first frame portion provided with a first wheel assembly, a second frame portion provided with a second wheel assembly, the second frame portion being assembled with the first frame portion for sliding movement along a lengthwise axis extending from a front to a rear of the child stroller apparatus, and an expandable storage basket spanning across the first and second frame portions. The storage basket includes a first and a second basket frame portion respectively attached to the first and second frame portion, the first and second basket frame portions being movable away or toward each other for expanding or contracting the storage basket as the second frame portion slides relative to the first frame portion for increasing or reducing a distance between the first and second wheel assemblies.
US10435057B2
A collapsible chassis for strollers includes a base frame supporting at least one front post and at least one rear post with wheel assemblies. The base frame further supports at least one handle tube. An actuation element is supported by the base frame and is actuated by the user to move the chassis from the open condition to the closed condition. The actuation element is movable with respect to both the handle tube and the movable post and is connected by way of a first kinematic connection element to the movable post and by way of a second kinematic connection element to the handle tube. Actuating the actuation element causes the rotation of the movable post and handle tube. A third kinematic connection element is provided which includes an articulation element adapted to cause a motion of mutual approach in a transverse direction of the two rear posts.
US10435054B2
A carriage having a frame which includes a plurality of elongated frame components. A first attachment point couples a first and second elongated frame component. A second attachment point couples a third and fourth elongated frame component. A transverse elongated frame component couples to the first and second attachment points. A rotation lock is disposed on the transverse elongated frame component. The rotation lock is configured to prevent rotation of the transverse elongated frame component in a locked configuration.
US10435053B2
When an event prevents a train from moving along a route in a nominal direction, this method makes it possible to cause it to circulate in an opposite direction by: selecting (120) an origin zone and an output signal; drawing (130) a pseudo-route on the successive zones between the origin zone and the output signal; opening (140) the pseudo-route by associating a sub-route with each zone, corresponding to the reservation of said zone for said train; informing (150) the train that it must circulate in the opposite direction; determining (160) a movement authorization for the train from sub-routes that are open and a list of obstacles that is updated regularly; sending (180) the movement authorization to the train, the determination (160) and transmission (170) steps being iterated until the train crosses the output signal.
US10435051B1
The present invention provides a system for preventing an accident that minimizes the number of monitor devices and prevents a collision accident to reduce the work and cost burdens. The system for preventing an accident 1 of the present invention includes an imaging device 10, a monitor server 20, and a warning device 60. The control unit 30 of the monitor server 20 executes the area receiving module 31 to receive input of an approach area as an area where a vehicle approaches and a danger area where is danger from an approaching vehicle based on a base image taken by the imaging device 10. The control unit 30 executes the time period judgment module 33 to judge whether or not it is a time period when a vehicle enters the approach area. If a vehicle enters the approach area, the control unit 30 executes the second judgment module 35 to judge whether or not a person, etc., enters the approach area or the danger area. If a person, etc., enters the approach area or the danger area, the control unit 30 executes the warning module 36 to instruct the warning device 60 to provide warning information.
US10435048B2
A computer-implemented method for alerting a user to the presence of a fault in an electromechanical system in a railway infrastructure, the method comprising: receiving electrical usage data indicative of the value of an electrical usage parameter associated with the electromechanical system; receiving temperature data indicative of the present temperature of the electromechanical system; determining, based on a predetermined relationship between the electrical usage parameter and the temperature, whether or not the value of the electrical usage parameter is indicative of a fault in the electromechanical system and if so, issuing an alert to indicate the presence of the fault.
US10435047B2
A truck mounted braking system is provided with a mechanical pivot adjustment on the bake lever connected to the brake cylinder push rod to permit the braking force applied to the wheels to vary depending on the lading condition of the car, without involving additional pneumatic elements such as a pneumatic empty load device. The brake cylinder may be provided with a channel which permits the push rod to achieve different positions based on different positions of the brake cylinder push rod.
US10435043B2
A funicular intended particularly for transporting heavy loads between an upstream station (10) and a downstream station (12), comprises a track (14), preferably a railway, connecting the upstream station (10) to the downstream station (12), a vehicle (16) running on the track (14) and at least one towing cable (30) in closed loop having a first towing section (32.1) passing over a first pulley (20.1) of the upstream station and over a first return pulley (26) fixed to the vehicle (16) and a second towing section (32.2), in all ways separate from the first towing section and passing over the return pulley (26) and over a second pulley (20.2) of the upstream station (10).
US10435042B1
To provide a better way of protecting cargo on flatbed trucks, railcars, and so forth, the present inventor, devised among other things a cargo containment system formed from a set of interconnectable weatherproof panels that can be configured to define a rectilinear containment structure over and around a volume of cargo.
US10435033B2
A driving support device includes an image output unit, an operation signal input unit, and a command output unit. The image output unit outputs an image information including a vehicle object representing a vehicle and a peripheral situation of the vehicle, to a display unit. The operation signal input unit receives an operation signal of a user with respect to the vehicle object in an image displayed on the display unit. The command output unit outputs an automatic driving control command corresponding to the received operation signal, to an automatic driving controller that controls automatic driving. If the operation signal input unit receives an operation signal of the user touching the vehicle object in the image displayed on the display unit, the image output unit outputs image information to the display unit in a selectable state, the image information including a plurality of operations automatically executable by the vehicle or a plurality of regions where the vehicle is movable when the vehicle object is touched.
US10435032B2
The present disclosure provides a vehicle and method for controlling the same. The vehicle includes: an input unit configured to receive a command to select a traveling mode; a controller configured to determine an Advanced Driver Assistance System (ADAS) setting parameter based on a traveling mode selected through the input unit and a driving pattern of a driver; and a display configured to display setting information regarding the determined ADAS setting parameter.
US10435031B2
A vehicle control device can be mounted in a vehicle. A receiver receives information from a wireless device mounted in another vehicle. A determiner determines whether or not to switch an automatic steering mode to a manual steering mode on the basis of the information received by the receiver. A notifier prompts a driver of the vehicle to switch the automatic steering mode to the manual steering mode in a case where the determiner determines to switch the automatic steering mode to the manual steering mode.
US10435030B2
A function monitor for a system, such as an advanced driver assistance system, comprising a first function monitor element and a second function monitor element, said first function monitor element configured to receive and collate sensor data from a plurality of sensors associated with the system and send a function warning signal to said second function monitor element when said sensor data from one or more of the plurality of sensors is indicative of a functional irregularity.
US10435028B2
The present disclosure relates to an apparatus (1) for estimation of a vehicle state. The apparatus (1) includes a controller (21) configured to determine a first estimation of the vehicle state in dependence on at least one first vehicle dynamics parameter. A filter coefficient (FC) is calculated based on a first vehicle operating parameter. An operating frequency of a first signal filter (35) is set in dependence on the determined filter coefficient (FC) and the first estimation is filtered to generate a first filtered estimation of the vehicle state. The present disclosure also relates to a vehicle; and to a method of estimating a vehicle state.
US10435021B2
A vehicle control device includes a lane determining unit which, in the event there is a branching path or a merging path in a planned travel route of a host vehicle, is adapted to determine whether or not a lane in which the host vehicle is traveling differs from a lane in which the branching path or the merging path exists, and a lane change instructing unit which, in the event it is determined by the lane determining unit that the lane in which the host vehicle is traveling differs from the lane in which the branching path or the merging path exists, is adapted to set a route so that the host vehicle automatically performs a lane change into the lane in which the branching path or the merging path exists.
US10435016B2
Motorcycles can become unstable when operating at high speeds and at high cornering levels. For example, they can exhibit an oscillation at the rear wheel commonly known as “weave.” A system and method is provided which utilizes a high-fidelity computer simulation model of a 2- or 3-wheel motorcycle to predict operating states such as yaw rate, lateral acceleration and roll angle for a stable motorcycle at a given speed and steer angle. The operating state of a physical motorcycle can be measured and compared to that of the model at every instant in time to determine if the operating state of the physical motorcycle differs from that of the simulation model in such a way as to indicate loss of stability. The nature of that difference can then be used to intervene in the operation of the motorcycle independent of driver actions by application of brakes, modulating the engine torque or applying torques to urge the steering system in a corrective direction. Thus by comparing the physical response of the motorcycle to that of the computer model in an on-board controller these interventions can be applied at a time and intensity to stabilize the motorcycle and prevent a loss of control.
US10435006B2
A method for checking the braking force in a vehicle includes adjusting a brake piston with a vehicle hydraulic brake that has a braking force booster and with an electromechanical braking device that has a brake motor so as to generate a braking force. The hydraulic braking medium volume that corresponds to the displacement of the brake piston via the brake motor is compared to a hydraulic reference volume.
US10435001B2
In order to provide a hydraulic actuating system for actuating a parking lock of a motor vehicle, which hydraulic actuating system manages with as few components as possible which are simple, robust, relatively insusceptible to faults and inexpensive, with a simultaneously low installation space requirement, and the hydraulic layout of which hydraulic actuating system makes a simple actuation and a simple movement possible for locking and unlocking the parking lock, it is provided that a pumping device which can operate bidirectionally with a locking delivery direction and with a releasing delivery direction is used as pumping device, and check valves are arranged in the hydraulic circuit in such a way that, by way of actuation of the pumping device in the locking delivery direction, the parking lock moves into the locked position and, upon actuation of the pumping device in the releasing delivery direction, the parking lock moves into the released position.
US10434988B2
A method for controlling access of a user to a physical device which is provided with an access control unit that can block and release access to functions of the physical device includes the provision of a central control platform and a mobile access device. An identification check of the user is carried out, the user being identified by the mobile access device. Following a successful identification check, a wireless communication link is established between the mobile access device and the access control unit of the physical device. Identification information and unique access data are transmitted from the mobile access device to the access control unit. The access control unit ascertains the access rights of the user to the physical device using the received information and additional information from the central control platform.
US10434982B2
Various embodiment of the present disclosure provide a system and method for disabling a passive entry passive start system (PEPS) of a vehicle. In one embodiment, the system and method of the present disclosure enable a user of the vehicle to disable the standard PEPS operations so that the vehicle control module will not unlock the vehicle or automatically start the vehicle as it would under standard operation.
US10434975B2
A seatbelt assembly includes a seatbelt, a conductive sensing conductor and a conductive shield. The seatbelt has a lap band. The conductive sensing conductor is fixed to a first side of the lap band. The conductive shield is fixed to a second side of the lap band and is substantially aligned with and substantially overlaps the sensing conductor. An insulating layer is disposed between the sensing conductor and the conductive shield.
US10434971B2
A curtain airbag device capable of preventing a cushion from damaging a front pillar trim or being caught by the front pillar trim upon deployed. A cushion 102 of a curtain airbag device 100 is inflated and deployed at a side wall of a vehicle interior to restrain an occupant. The curtain airbag device 100 includes: a cushion 102 having a bag shape and inflated and deployed on the vehicle front side of a passenger seat; and a first strap 148. The first strap 148 has one end 156 attached to a front pillar 104 and the other end 162 attached on the vehicle inner side of the cushion 102 in an elongate stored form. The first strap 148 moves to the vehicle inner side and is strained by inflation and deployment of the cushion 102 pushing out a front pillar trim 184 that covers the front pillar 104 to the vehicle inner side.
US10434966B2
A computer determines a gap distance behind a front seat. In response to detecting an impact of the vehicle, the computer selectively controls deployment of an airbag based at least in part on a gap distance behind the front seat. The computer may determine the gap distance based on seat position data, image data, weight data, triangulation data, and proximity data. The computer may be incorporated into an airbag deployment control system for deploying the airbag behind the front seat.
US10434965B2
The present application discloses a vehicular safety seat for a passenger including a detector configured to detect a plurality of physiological parameters and a plurality of environmental parameters associated with the passenger; a first transmitter configured to transmit a first set of physiological and environmental parameters detected by the detector; a first receiver configured to receive a control signal for controlling at least one parameter from among the plurality of physiological and environmental parameters based on a determination that a monitored parameter in the first set of physiological and environmental parameters has a first value that exceeds a corresponding monitored parameter threshold value; and an adjustor configured to adjust at least one of the plurality of environmental parameters based on the control signal.
US10434961B2
Adjustable license plate brackets for vehicles comprising a first bracket element that is secured to a vehicle; a second bracket element having an upper end to be connected to a license plate and a lower end disposed upon the first end of the first bracket element; and a third bracket element having an upper end to be connected to a license plate and a lower end disposed upon the second end of the first bracket element. The second bracket element and the third bracket element are configured to be connected to the first bracket element at a plurality of positions, implemented using an elongated aperture with a plurality of notches into which a bracket element connector can be inserted, respective so that a distance between the upper ends of the second and the third bracket elements varies to accommodate license plates with different sizes.
US10434959B2
A vehicle interior trim assembly includes a first trim component and a second trim component. The first trim component includes a first base plate and a protrusion. The second trim component includes a connection clip and a connection suspension. An opening in the connection clip receives the protrusion, and the connection clip engages an underside surface of the protrusion to yield a snap fit between the connection clip and the protrusion. The snap fit secures the second trim component to the first trim component. The connection suspension is configured to yield an interference fit between the connection suspension and one of the first base plate and the protrusion when the second trim component is assembled to the first trim component. The interference fit yields a biasing force that biases the connection clip toward the underside surface of the protrusion to limit movement between the first and second trim components.
US10434957B2
To prevent a vehicle body member from being damaged when an interior component is attached. In a vehicle interior structure, an interior component is fastened to a vehicle body member provided interior of a vehicle by an engagement portion. The engagement portion includes a hole formed in the vehicle body member, a claw portion provided in the interior component, and a pedestal provided in a base part of the claw portion. A guide portion is provided in the vehicle body member to guide the pedestal before the claw portion is fitted into the hole to engage with the hole, so as to prevent an end portion of the interior component from contacting the vehicle body member.
US10434941B1
A wearable device is provided that includes a receiver, a processor, and a transducer. The receiver is configured to receive speed limit data indicative of a posted speed limit corresponding to a route or road upon which the wearable device is traveling. The processor is configured to compare the speed limit to a current speed of the wearable device and/or a vehicle in which the user wearing the wearable device is driving. The transducer is configured to deliver a haptic or other notification to a user upon which the wearable device is worn when the current speed exceeds the speed limit or exceeds the speed limit by a predetermined amount. As a result, safer driving and vehicle collision avoidance may be facilitated. Safe driving auto insurance discounts may be provided to drivers that use the safe driving or speed limit warning functionality discussed herein.
US10434940B1
Systems and methods for providing active ceiling display on the ceiling of a vehicle that is manipulated by occupant gestures. A display provides an area of illumination that illuminates at least a portion of the interior of a vehicle. The occupant manipulates aspects of the area of illumination with gestures. The system causes an area of illumination to follow the movements of an occupant. The system changes aspects of illumination within the vehicle based on the activities of an occupant, mood of the occupants, and ambient lighting inside and outside the vehicle.
US10434937B2
A lighting unit is mounted on a vehicle. A driving unit drives the lighting unit to move an illumination position. When a microcomputer detects getting-on, the microcomputer controls the driving unit, to move an illumination position of the lighting unit along a track running across an illumination area around feet outside the vehicle, an illumination area on a driver's seat, an illumination area on a starter switch, and an illumination area on a steering wheel.
US10434934B2
A high mount stop lamp mounted on a rear portion of a roof of an automobile is provided. The high mount stop lamp includes a flat light guide arranged below a resin roof panel. The light guide includes a front end and a rear end. The high mount stop lamp also includes a light source opposing the front end of the light guide. The rear end of the light guide is located on or proximate to a rear end of the roof panel to function as a light emitting portion.
US10434931B2
A light distribution switching device of a head lamp may include: a housing installed at the front of a light source of the head lamp; a shield part rotatably installed in the housing, and adjusting movement of light irradiated from the light source depending on a rotational position; a rotating gear mounted on the shield part and rotated with the shield part; a driving part rotating a driving gear engaged with the rotating gear; and an elastic return part installed on the shield part, and moving the shield part to the original position when the driving part is stopped.
US10434927B2
The adjustment system comprises at least one pair of adjustment apparatuses. For each optical assembly, one adjustment apparatus is adapted to turn the optical assembly around the turning axis (α; β) independently of the other optical assembly. The adjustment system further comprises an additional adjustment apparatus connected to a first adjustment apparatus and adapted to transfer its movement to the movement of this adjustment apparatus; and a connecting member connected to the additional adjustment apparatus and to a second adjustment apparatus at the same time, and adapted to transfer the movement of the additional adjustment apparatus to the movement of the second adjustment apparatus (. If the additional adjustment apparatus is connected to the first adjustment apparatus and the connecting member is connected between the additional adjustment apparatus and the second adjustment apparatus, turning movement of one optical assembly will automatically induce a turning movement of the other optical assembly.
US10434923B2
A conveyor system for loading a trailer is disclosed. The conveyor system includes a support frame adapted to couple to a floor of a trailer, a conveyance mechanism coupled to the support frame and configured to extend from a rear of the trailer toward a front of the trailer, and a conveyor rail arranged to extend between and interconnect the support frame and the conveyance mechanism.
US10434922B2
An inertia-driven dump load apparatus is provided in association with motor vehicles. The inertia-driven dump load includes a container defined by two side walls and a front wall; and at least one pivotable connection means connecting the container to the vehicle bed. To operate the inertia-driven dump load apparatus, the apparatus is first placed within a vehicle bed. Once the apparatus is in place, material to be dumped can be loaded into the apparatus. Then, the vehicle is driven to a location where the dumping of the materials is desired. Finally, a force is applied to the apparatus such that the apparatus moves across the vehicle bed so that the apparatus tips over a tailgate of the vehicle bed so that the material to be dumped is dumped.
US10434918B2
A vehicle seat includes a cushion and a seatback coupled with the cushion and rotatable between collapsed and open positions. The seatback includes a first inflatable bladder within an interior of the seatback, a pneumatic actuator fluidically coupled with the bladder and configurable between a compressed condition and a withdrawn condition, and a control cable coupled between the actuator and the cushion for linking the configuration of the actuator with the position of the seatback.
US10434917B2
An approaching-body warning device causes a driver to recognize a direction in which a detection target approaches to an own vehicle and a distance thereto with tactual feeling provided by a vibration device. An approaching-body warning device includes a detection system that detects automobiles and the like approaching to an own vehicle from various directions. A vibration device includes a plurality of vibrating body pairs, each being a right-left pair of vibrating bodies, arranged along a vehicle travelling direction at the interior component with which a driver's body is to be in contact. When the detection system detects the detection target approaching from one or a plurality of directions, a vibration control unit controls the vibration device to cause the vibrating body pairs to vibrate in accordance with each direction in which the detection target detected by the detection system is approaching to the own vehicle and a distance therebetween.
US10434915B2
A guide sleeve, for receiving a rod of a headrest, includes a sleeve body that has a rod receptacle for receiving the rod and an elastic region that is force-loaded in a direction of the rod receptacle in order to fix the rod in the rod receptacle. A spring element arranged on the outer contour of the sleeve body spring-loaded the elastic region. The spring element has a contact region adjacent to the elastic region, is configured as a clip that partially embraces the sleeve body and has a width in a sleeve body axial direction. The spring element includes a strip main body and the contact region is configured as a protuberance between two first bending points extending across the entire width of the main body. A vehicle seat for a motor vehicle has a backrest and a headrest, wherein the guide sleeve fastens the headrest to the backrest.
US10434911B2
A vehicle seat includes; a pair of frame members, the frame members forming a frame of at least one of a seat cushion and a seat back and being disposed at positions surrounding a seat region supporting an occupant with an interval therebetween; and a cloth spring member bridged between the frame members to cover the seat region. The cloth spring member has a shorter length in a bridging direction at least on one end side of the frame member in a longitudinal direction of the frame member than in a center portion of the frame member in the longitudinal direction; and the cloth spring member has elasticity.
US10434905B2
A seat assembly forms a substantially horizontal plane for an exposed surface of each of a lower seat cushion and a seatback cushion of a seatback. The seat assembly comprises a lifter mechanism for a rearward edge of the lower seat cushion. The lifter mechanism further comprises a main lift arm coupled to the edge, a slotted support arm having a distal end thereof pivotally coupled to a distal end of the main lift arm, a linkage arm pivotably coupled with the main lift arm and a slot in the slotted support arm, and a translational arm coupled with the linkage arm. The rearward edge of the lower seat cushion is raised by the translational arm being displaced to a fully displaced position to thereby raise a distal end of the linkage arm and the lift arm.
US10434900B2
A vehicle control system includes a seat (41) on which an occupant of a vehicle sits, a first protruding mechanism (45) configured to move a pushing member (45A) provided inside the seat to adjust a protruding position and a displacement of the seat, a second protruding mechanism (46) configured to inject a gas or liquid into a bag-like member (46B) provided inside the seat to adjust the protruding position and the displacement of the seat, and a seat control unit configured to control the first protruding mechanism to cause at least a part of a contact portion between the occupant and the seat to protrude in a case that the vehicle performs a first driving mode having a degree of automated driving less than a predetermined reference and to control the second protruding mechanism to cause at least a part of the contact portion between the occupant and the seat to protrude in a case that the vehicle performs a second driving mode having a degree of automated driving equal to or higher than the predetermined reference.
US10434899B2
The present disclosure provides a magnetic field communication ground power system of an electric vehicle, the system includes a reflux rail and multi-segment conductive rail mounted on a ground. The electric vehicle runs through the reflux rail, and receives electric power from the conductive rail through conductive boots so as to drive the electric vehicle to move. The system further includes: a plurality of driving positive electrodes configured to connected to the conductive rail; at least one electromagnetic controlling system configured to turn on or turn off the driving positive electrodes; a plurality of magnetic controlling systems configured to collect a position of the electric vehicle on the reflux rail, wherein the magnetic controlling systems transmit the sampled position of the electric vehicle to the electromagnetic controlling system, and the electromagnetic controlling system turns on or turns off voltage of the driving positive electrodes.
US10434897B2
A vehicle high-voltage system equipment unit includes a high-voltage system equipment, and a cooling fan for taking in air from a passenger compartment. The high-voltage system equipment is cooled with air taken in from the passenger compartment, the cooling fan is provided on an upstream side of the high-voltage system equipment, and an air discharge portion is provided on a downstream side of the high-voltage system equipment, a branch portion for dividing a flow of air used to cool the high-voltage system equipment is provided in the air discharge portion, an air flow regulating portion is provided on an upstream side of the branch portion, and the air flow regulating portion is formed integrally with the high-voltage system equipment.
US10434887B2
A vehicle includes an electric power storage device, a charging inlet, an electric power reception device, and a controller. The controller is configured to start charging the electric power storage device when the time reaches a set time set in advance in a case where scheduled charging control that starts charging the electric power storage device at the set time is planned to be executed in a state in which electric power is receivable through either the charging inlet or the electric power reception device. The controller is configured to execute the contacted charging control by suppressing execution of the scheduled charging control that starts the contactless charging control, when the charging connector is connected to the inlet in a case where the scheduled charging control that starts the contactless charging control at the set time is planned to be executed.
US10434885B2
A landing platform for an unmanned aerial vehicle, including a plurality of substantially funnel-shaped centering housings configured to cooperate with a corresponding plurality of projections of the aerial vehicle for reaching a predetermined landing position. The platform can include a mechanism for recharging the battery of the aerial vehicle and/or with an arrangement for serial data transfer.
US10434882B2
A track-bound vehicle converter comprises a block-wave generator (20) configured to be connected to a direct voltage source (21) and connected to a series resonance link (34), or to an inductive link, for providing the input of a direct converter (41) with semi sinusoidal current pulses. The direct converter has at least one phase leg (42-44) having on one hand one switch (45-47) connected to the link (34) and able to block voltages in both directions thereacross and conduct current in both directions therethrough and on the other a capacitor (48-50) connected in series therewith. The voltage across the capacitor (48-50) of the direct converter is used to provide a converter output with an alternating voltage.
US10434879B2
The present invention relates to an input/output device provided in a vehicle, the device including a plurality of sticks arranged in columns in a first direction and rows in a second direction, a driving unit configured to move at least one of the sticks in a direction perpendicular to the first and second directions, and a processor configured to control the driving unit such that the sticks have the same height or different heights from a reference plane defined by the first and second directions, wherein the processor controls the driving unit so that one or more buttons defined by a height difference of the sticks are formed, based on a driving state of the vehicle, and wherein the one or more buttons are varied according to the driving state of the vehicle.
US10434878B2
An information system for a vehicle is provided, as is a corresponding method for operating the information system and a thereto related computer program product.
US10434877B2
A driver-assistance method and a driver-assistance apparatus are provided. In the method, a movement trajectory of wheels in surroundings of a vehicle when the vehicle moves are calculated. Multiple cameras disposed on the vehicle are used to capture images of multiple perspective views surrounding the vehicle, and the images of the perspective views are transformed into images of a top view. A synthetic image surrounding the vehicle is generated according to the images of the perspective views and the top view. Finally, the synthetic image and the movement trajectories are mapped and combined to a 3D model surrounding the vehicle and a movement image including the movement trajectories having a viewing angle from an upper rear side to a lower front side of the vehicle is provided by using the 3D model when backing up the vehicle.
US10434873B2
An inlet check valve intended to be entirely located within an internal volume delimited by a liquid tank of a vehicle and a filler pipe welded to the tank, the filler pipe defining a downstream direction followed by a liquid filling the tank, and an upstream direction opposite thereto the inlet check valve comprising a tube and, at the upstream end of the tube, resilient means for adapting the form of the tube to the internal wall of the filler pipe. The inlet check valve comprises hook means for securing the tube to an internal wall of the filler pipe and prevent the inlet check valve from moving within the filler pipe. The tube bears a skirt ending with an edge which can merge with the filler pipe wall when the latter is welded to the tank, making the edge a seal part of the inlet check valve.
US10434863B2
A multimode clutch may be adapted for selectively connecting and disconnecting front and/or rear axles from respective internal combustion engine and electric motor powertrains connected to such front and rear driving axles in a through-the-road hybrid vehicle. For example, the engine may be part of a front axle driven powertrain connected to the front wheels, while the motor may be part of a separate rear axle driven powertrain connected to the rear wheels, or vice versa. By selective disconnection of an axle not being actively driven, a real time reduction in parasitic losses may be achieved, leading to higher overall operating efficiencies. The multimode clutch offers greater flexibility over the use of standard friction clutches; each multimode clutch may provide four distinct operational modes for accommodating a wide diversity of driving conditions. For example, bi-rotational freewheeling of the rear axle may occur whenever the motor is not in use.
US10434859B2
A vehicle includes a vehicle body, an electromotive driving unit mounted on the vehicle body, an engine operable with a liquid fuel, a generator that generates electric power, and a control device including a power generation control unit and an electric power output unit. The power generation control unit outputs a signal for controlling the engine and the generator, the electric power output unit outputting electric power generated by the generator to the electromotive driving unit. The control device in combination with the engine and the generator constitutes a physically integrated unit that is mountable to and dismountable from the vehicle body. The control device is configured to output a store visit promotion signal to an informing device while the physically integrated unit is mounted on the vehicle body, to prompt a visit to a store where the physically integrated unit is replaceable.
US10434850B2
A tarp deployment mechanism for covering a container with a flexible cover sized to cover the container in a deployed configuration is disclosed. The deployment mechanism comprises: a bail member spanning a width of the container and carrying one end of the flexible cover, the bail member movable to an extended position in which the one end of the flexible cover is adjacent one end of the container, the bail member having at least one hollow body portion that defines at least one cavity that extends throughout the hollow body portion of the bail member; and at least one cable arranged within the at least one cavity defined by the at least one hollow body portion of the bail member. The cable prevents complete dislocation of the bail member in the event of its fracture.
US10434843B2
An air-conditioning unit for a vehicle includes an air-conditioning case; a cooler disposed in the air-conditioning case and adapted to cool air flowing through the air-conditioning case; and a blower disposed on an air-flow downstream side of the cooler and adapted to blow the air into a vehicle interior. The air-conditioning case includes a drain-hole formation portion that forms a drain hole to discharge condensed water generated in the cooler toward an outside of the air-conditioning case. The air-conditioning case is provided with a cooling structure that cools suction air drawn from the drain hole into the air-conditioning case.
US10434836B2
A vehicle walking beam assembly includes a support beam and a mount member configured to rotatably mount the support beam on the chassis. A gear assembly with a gear train and a gear housing is supported by the support beam. The gear train includes a gear with a first journal surface, and the housing includes a second journal surface. The walking beam assembly additionally includes an input drive assembly that delivers input torque from the engine to the gear train. Moreover, the walking beam assembly includes a reaction member connected to one of the gear housing and the gear of the gear train. The reaction member is configured to transfer a reaction force between the chassis and the one of the gear housing and the gear of the gear train as the first journal surface journals on the second journal surface.
US10434832B2
A security device for a trailer hitch which includes a ball receptor, the device comprising a base plate, a deflector secured to the base plate, the deflector having an aperture formed therein, the deflector having an inwardly directed upper portion, a cover hingedly connected to the base plate, the cover being movable between an open position permitting access to the ball receptor and a closed position denying access thereto, a locking device mounted to the cover, the locking device including a housing, a plunger mounted within the housing, the plunger being movable between an extended position and a retracted position, the plunger being spring biased to the extended position, and the locking device being secured such that the plunger enters the aperture when the cover is in a closed position.
US10434831B2
In order to provide a trailer coupling device for motor vehicles, comprising a rear-side cross member which is mountable on a vehicle body, a supporting unit provided on the cross member which holds a ball neck receiving sleeve having a ball neck receptacle in which a ball neck incorporating a coupling ball is insertable and fixable therein, in which the ball neck receiving sleeve is minimally visible and disturbing when the ball neck is not inserted, it is proposed that the supporting unit comprises a pivot bearing unit by means of which the ball neck receiving sleeve is pivotable from a working position in which the ball neck is insertable therein in order to use a trailer, into a rest position in which an insertion opening of the ball neck receiving sleeve is arranged outside a visible region.
US10434830B2
An attachment for use with a safety chain which has a leading link and a following link, the attachment having a clevis with first and second lateral side sections and an opening between the side sections into which a leading end of the leading link is receivable; and a pin receivable by the first and second side sections so as to extend across the opening to couple the leading link to the clevis and a portion of the clevis defined between the first and second sections has a configuration complementary to a configuration of the leading end of the leading link; and/or portions of the first and second side sections have configurations complementary to configurations of portions of a leading end of the following link, such that there is a close fit between the clevis and chain when the leading link is coupled to the clevis by the pin.
US10434818B2
The present disclosure relates to a decorative panel made of flat glass for electronic household appliances, in particular, for large stationary household appliances. The decorative panel comprises a base body made of thermally tempered flat glass with an operational front and an operational back, and has at least one digital print on the operational back.
US10434817B2
A heat transfer label is disclosed. The heat transfer label comprises a special heat stable release which strongly adheres to the carrier, offers a highly ink and adhesive wettable surface, stays intact under heat transfer bonding conditions, releases easily, leaves no contamination on the transfer or fabric, and enables durable replication of the release surface finish onto the resultant transfers.
US10434816B2
A stylus suitable for an electronic device is provided. The stylus comprises a pen barrel and a core. The pen barrel has a sidewall and at least one first protrusion, and the first protrusion is located at an inner side of the sidewall. The core movably passes through the pen barrel. The core has a pen tip and at least one second protrusion. Under a first status, the first protrusion and the second protrusion are dislocated from each other. Under a second status, the first protrusion and the second protrusion are aligned with each other to make a part of pen barrel expand and deform.
US10434813B2
A method for producing a security document, with a thermographic substrate wherein the thermographic substrate is caused to undergo a color change depending on temperature effect in at least one first region A film element is arranged in such a way that the film element is arranged between the at least one first region of the thermographic substrate and a thermal print head. At least one first item of information is introduced by means of the thermal print head by activation of the color change in the at least one first region of the thermographic substrate, wherein the thermal print head, during the introduction of the at least one first item of information is in contact with the film element in such a way that the temperature effect causing the activation of the color change is transferred from the thermal print head through the film element to the at least one first region of the thermographic substrate.
US10434804B2
The present teachings relate to various embodiments of a gas enclosure system that can have various components comprising a particle control system that can provide a low-particle zone proximal to a substrate. Various components of a particle control system can include a gas circulation and filtration system, a low-particle-generating motion system for moving a printhead assembly relative to a substrate, a service bundle housing exhaust system, and a printhead assembly exhaust system. In addition to maintaining substantially low levels for each species of various reactive species, including various reactive atmospheric gases, such as water vapor and oxygen, for various embodiments of a gas enclosure system that have a particle control system, an on-substrate particle specification can be readily met. Accordingly, processing of various substrates in an inert, low-particle gas environment according to systems and methods of the present teachings can have substantially lower manufacturing defects.
US10434800B1
A media feeding system comprises a driver configured to rotate a media roll in a first direction; a vacuum roller positioned in a media feed path and configured to rotate in the first direction; and a media end detecting sensor positioned in the media feed path, the media end detecting sensor being configured to detect a leading edge of the media; wherein the driver rotates the media roll in a second direction opposite the first direction in response to the sensor detecting the leading end of the media.
US10434798B2
A printing apparatus which appropriately deals with a medium jam occurring on the transportation belt is provided.
US10434797B2
An image forming apparatus includes an image forming portion including an image bearing member, a developing device, and an intermediary transfer belt; a feeding device including a feeding belt; an ultraviolet irradiation portion; a cover; a first shielding plate extending in a direction perpendicular to the feeding direction on a feeding surface of the feeding belt from an inner surface of the cover downwardly with respect to the vertical direction and configured to shield the intermediary transfer belt from the ultraviolet radiation toward the intermediary transfer belt; and a second shielding plate provided on the cover and extending downwardly with respect to the vertical direction along an outer surface of the intermediary transfer belt. The second shielding plate is configured to shield the intermediary transfer belt from the ultraviolet radiation toward the intermediary transfer belt.
US10434791B2
A transfer printing device includes a transfer ribbon, a print unit, a mark sensor and a controller. The transfer ribbon includes a transfer layer that is attached to a carrier layer. The transfer layer includes a series of transfer sections. The controller is configured to perform a print operation, in which a transfer section that is available for printing is selected by detecting an absence of a used mark in a predetermined position on the transfer ribbon corresponding to the transfer section using the mark sensor. An image is printed to the selected transfer section and a used mark is printed on the transfer ribbon using the print unit. At least a portion of the used mark is in a predetermined position relative to the selected transfer section and is outside the selected transfer section.
US10434788B2
A liquid storage unit includes a liquid container, a spout, a plate-shaped member, and a bag. The liquid container is provided with a storage portion configured to store a liquid inside of a flexible sheet. The spout is provided on the liquid container, and is configured to supply the liquid stored in the storage portion to an inkjet printer in a state in which the spout is connected to the inkjet printer. The plate-shaped member is configured to sandwich at least a portion of an end portion of the liquid container from both sides in an orthogonal direction that is orthogonal to a surface of the sheet. The bag is configured to enclose the liquid container and the plate-shaped member. An inside surface of the bag contacts the plate-shaped member when the inside of the bag is in a depressurized state.
US10434787B2
A printer includes a head and a connector. The head is configured to eject ink. The connector is configured to connect a first storage to the head, and configured to connect a second storage to the head via a joint component. The first storage stores the ink. The second storage stores a greater amount of the ink than the first storage.
US10434786B2
A liquid supply unit that includes a liquid ejection apparatus and configured to be mounted onto a holder unit that has a liquid introducing needle that extends in a first direction includes an outer shell, a liquid supply port, and an engagement structure including a first engagement portion, in which the first engagement portion is disposed on a mounting direction side of the outer shell at a position that overlaps with the outer shell when the liquid supply unit is viewed from the demounting direction side.
US10434782B2
The present teachings disclose various embodiments of a printing system for printing a substrate, in which the printing system can be housed in a gas enclosure, where the environment within the enclosure can be maintained as a controlled printing environment. A controlled environment of the present teachings can include control of the type of gas environment within the gas enclosure, the size and level particulate matter within the enclosure, control of the temperature within the enclosure and control of lighting. Various embodiments of a printing system of the present teachings can include a bulk ink delivery system that can be external to a gas enclosure. A bulk ink delivery system according to the present teachings can supply ink to a local ink delivery system that is internal to the gas enclosure. Various embodiments of a local ink delivery system of the present teachings can be proximal to a printhead device assembly, and can include a two-stage ink supply having a local ink replenishment reservoir that is configured to supply a local ink dispensing reservoir to a constant volume. According to the present teachings, a local ink dispensing reservoir can be in flow communication with a plurality of printhead devices. As such, a two-stage local ink delivery system maintaining a constant volume in a local ink dispensing reservoir can provide constant head pressure to the plurality of printhead devices.
US10434771B2
An apparatus includes a recording head including a first discharge port array and a second discharge port array, the first and second discharge port arrays being shifted and arranged in a first direction so that part of the discharge ports arranged at an end portion of the first discharge port array in the first direction and part of the discharge ports arranged at an end potion of the second discharge port array in the first direction are located at the same positions in the first direction. The plurality of discharge ports in each of the first and second discharge port arrays is obliquely arranged at a predetermined tilt with respect to the first direction. Discharge timing is adjusted based on the tilt of the discharge port arrays.
US10434770B2
A temperature of one printing element is adjusted based upon a temperature of another of printing element.
US10434768B2
In some examples, a printing system comprises a plurality of microelectromechanical systems (MEMS) dies comprising printing fluid jets, a printhead assembly (PHA) application specific integrated circuit (ASIC), and a substrate comprising the plurality of MEMS dies and the PHA ASIC. The PHA ASIC is to process image data into a plurality of data signals that define a firing pattern, and transmit the data signals through transmission lines on the substrate to the plurality of MEMS dies. The printing fluid jets of the plurality of MEMS dies are to fire in response to the data signals.
US10434765B2
A specifying section specifies in printing data a first dot position at which a defective nozzle discharges an ink droplet to print the ink droplet on a medium when the defective nozzle is not defective, but is normal, and specifies in printing data a second dot position different from the first dot position based on priority information in which priority is set for each pixel. A data correcting section corrects the printing data. The collecting corresponds to allocating an amount of ink of the first dot position to the second dot position. When the first dot position at which the ink droplet is provided to the medium if the defective nozzle is not defective is specified, a neighboring second dot position different from the first dot position is specified based on the preset priority information, and the data correcting section corrects the printing data so as to allocate the amount of ink to the second dot position based on the mount of ink of the first dot position.
US10434755B2
A fire barrier laminate including: at least one non-fibrous fire barrier layer directly or indirectly coated onto at least one first polymeric flame propagation resistant film layer; at least one second film layer proximate to the non-fibrous fire barrier layer opposite the first polymeric flame propagation resistant film layer; at least one scrim layer disposed: (i) between the non-fibrous fire barrier layer and the first polymeric flame propagation resistant film layer; and/or (ii) between the non-fibrous fire barrier layer and the second film layer; and/or (iii) proximate to the first polymeric flame propagation resistant film layer opposite the non-fibrous fire barrier layer; and/or (iv) proximate to the second film layer opposite the non-fibrous fire barrier layer. Also, a method of making the fire barrier laminate.
US10434742B2
A venting apparatus is disclosed herein. The venting apparatus comprises a substrate, such as a metal substrate or a specialty plastic substrate, having an opening therein and a fluoropolymer membrane, such as ePTFE, disposed over said opening and thermally bonded using a thermoplastic material to said substrate. This allows the fluoropolymer membrane to be directly bonded to the said substrate without using an adhesive layer.
US10434741B2
A composite molded article contains a metal molded article and a resin molded article, which are bonded to each other, in which the metal molded article has a roughened bonding surface, a surface layer portion of the metal molded article including the roughened bonding surface has: open holes containing: a stem hole that is formed in a thickness direction and has an opening on the side of the bonding surface, and a branch hole that is formed from an inner wall of the stem hole in a different direction from the stem hole, and the composite molded article is bonded in such a state that the resin permeates into the open holes formed on the bonding surface of the metal molded article.
US10434738B2
A waste compaction system for a vehicle includes a moveable trolley for storing waste, and a docking station integratable into a cabin monument for inserting the trolley. The trolley includes a housing having an opening for inserting waste, a vacuum waste compacting mechanism inside the housing and a first suction port accessible from outside the housing, the first suction port being couplable with the vacuum waste compacting mechanism. The docking station and the trolley are adapted to each other such that the trolley is engageable with the docking station, and wherein the docking station includes a second suction port couplable with a suction line in the vehicle and the first suction port. Resultantly, a lightweight and efficient waste compaction system is provided, which allows moving the trolley for collecting waste inside a cabin of the vehicle.
US10434737B2
A tire building drum has a drum shaft and a circumferential surface for receiving a tire component, wherein the circumferential surface is defined by segments which are radially movable between a contracted position in which the circumferential surface has a first radius and an expanded position in which the circumferential surface has a second, greater radius. The tire building drum includes cover plates, wherein each segment is provided with a first section having a first support surface for supporting the tire component and a second section with a second support surface for supporting the cover plate. Each second section is movable relative to its respective first section from a recessed position in which the second support surface is recessed with respect to first radius and an extended position in which the second support surface is raised towards the second radius.
US10434722B2
A blade support cradle is described, which can be used to support a section of a wind turbine blade using an array of vacuum clamps. The cradle provides a secure and reliable system for the support of a blade section during and after blade manufacture, allowing for various operations to be easily carried out on the surface of the blade section. A method for receiving a blade section in the cradle is further described. In addition, the cradle may be used as part of a blade post-moulding station in a method of manufacturing a wind turbine blade.
US10434716B2
Methods and apparatus relating to substructures for three-dimensional objects are described. In an example, a method comprises receiving a lattice model having a consistent dimensionality and determining a substructure model representing a three-dimensional material structure, the substructure model being based on the lattice model and specifying a variable material distribution. The substructure model may be populated with halftone threshold data to provide a three-dimensional halftone threshold matrix.
US10434705B2
A process for making an article by additive manufacture having resistance to dripping when burned comprising (1) depositing a multitude of thermoplastic monofilament strands using a fused deposition modeling apparatus in a pattern and (2) fusing the multitude of strands together to make an article of manufacture having voids therein; wherein the article of additive manufacture has (a) at least 50% of the monofilament strands oriented within 45 degrees of the long part of the axis; (b) the multitude of strands is greater than 10; (c) having a specific micro structure; and (d) is made from a thermoplastic polymer composition that is either the combination of a thermoplastic polymer with a flame retardant compound, a thermoplastic resin having flame resistant properties, or a combination of a thermoplastic resin having flame resistant properties with a flame retardant compound.
US10434704B2
Methods of additive manufacture using coreactive components are disclosed. Thermosetting compositions for additive manufacturing are also disclosed.
US10434701B2
Provided is a method for welding an accessory part made of a thermoplastic resin to a parison which is being molded into a tank body. The method includes steps of: forming the accessory part to include an annular portion having an annular shape and a plurality of projections each projecting from the annual portion in a radially inward direction; and pressing the annular portion and the projections into the parison to be welded to the parison. Also provided is a welding structure of a tank body made of a resin and an accessory part made of a thermoplastic resin and welded to a wall surface of the tank body. The accessory part includes: an annular portion having an annular shape; and a plurality of projections each projecting from the annular portion in a radially inward direction. The annular portion and the plurality of projections are welded to the wall surface.
US10434695B2
A method is described for operating an injection moulding machine, which has one or more movable machine parts which can be moved by suitable drives along specifiable travelling distances. Movement of a movable machine part is repeated cyclically. In order to reduce the movement times of the movable machine parts to a minimum, provision is made for one or more of the movable machine parts to successively reduce the power reserves of one or more of the drives associated with a movable machine part, until a specifiable minimum of power reserve is reached, wherein the minimum can be zero. In each cycle, the power reserve of the drive or drives is determined and is successively reduced, in particular from cycle to cycle. A movable platen, an ejector, a core puller, a plasticizing screw and/or an injection piston can be provided as movable machine part.
US10434693B2
An overmolding method for making thermoplastics articles of manufacture, for the perfumery and cosmetics fields, comprises the steps of: a) providing a first plastics material in a form suitable for an injection molding; b) providing an injection press, and molding by the injection press the first plastics material thereby providing a raw molded article of manufacture; c) associating with the raw article of manufacture made in said molding step: d) at least an insert element of a material different from the plastics material thereby providing an assembly of the raw molded article of manufacture and the insert element; and e) overmolding on the assembly at least a second plastics material thereby providing a finished molded article of manufacture.
US10434690B2
Disclosed are fluid transfer and evacuation structures formed in a vacuum bag operable for use in vacuum-assisted resin transfer molding, debulking, compaction, or similar processes. A reusable vacuum bag can be provided including an elastomeric membrane having a preform-contact surface and at least one textured surface formed in the elastomeric membrane. The textured surface can define a fluid transfer channel. At least one fluid extraction port can be provided in communication with the fluid transfer channel, the fluid extraction port being adapted for engagement to a vacuum pump to remove fluids from the fluid transfer channel. The textured surface defining the fluid transfer channel can be adapted to permit the flow of fluids between the elastomeric membrane and a base mold in communication with the elastomeric membrane when the fluid extraction port is engaged to a vacuum pump.
US10434677B2
A sawmill includes a four-stroke internal combustion engine having an output shaft for driving a sawblade. The output shaft has a longitudinal axis. The engine is mounted on the sawmill for rotation between a first operative position with the longitudinal axis of the output shaft extending at a first angle, and a second operative position with the longitudinal axis of the output shaft extending at a second angle transversely to the first angle. The engine has fuel injection to facilitate operation in the first and second operative positions and a lubrication system incorporating a wet sump. An oil pick up for the lubrication system is configured to pick up oil from the wet sump at both the first and second operative positions.
US10434672B2
A cutting tool for cutting building materials at a range of angles from vertical and/or horizontal and with an additional adjustment mechanism for adjusting the cutting angle up or down by a small angle. More specifically, this invention relates to a cutting tool including a base, a support surface, and a cutting platform, where the cutting platform can be set at a plurality of angles to the base including, but not limited to, angles of 22.5°, 30°, 45°, and 90°, and the support surface can be angled slightly up or down by a small amount, for example 1° or 2°, to slightly adjust an angle of the cut.
US10434663B2
An vacuum device includes a suction pad vacuumed on a to-be-vacuumed surface of a vacuum target, and a bellows tube having the suction pad at one end in a telescopic direction and having an internal space that is expanded and contracted by pressure of air, the telescopic member being elongated and contracted by expansion and contraction of the internal space.
US10434654B2
A parameter for detecting a target mark 5 is not required to be set for each camera repeatedly while a stereo camera 2 is calibrated. A calibration device 1 associates position information in an image coordinate system at a first camera 21 of a stereo camera 2, position information in an image coordinate system at a second camera 22 of the stereo camera 2, and position information in a robot coordinate system at a robot 4. The calibration device comprises: first parameter setting unit 102 that sets a first parameter for detecting a target mark 5 attached to the robot 4 from data about an image captured by the first camera 21; and a second parameter setting unit 104 that sets a second parameter for detecting the target mark 5 from data about an image captured by the second camera 22 based on the first parameter.
US10434643B1
A device is provided. The device includes a worm drive comprising a worm and a worm gear. The device also includes an actuator comprising a motor, a shaft, and the worm, wherein the shaft is configured to rotate about a shaft axis, and the actuator is configured to (i) drive the worm drive, and (ii) move linearly along the shaft axis. The device also includes a first spring and a second spring, wherein the second ends are fixed, and wherein the first and second springs are configured to resist movement of the actuator along the shaft axis in opposite directions as a result of forces transmitted through the worm drive. The device further includes a linear position encoder configured to determine a position of the actuator along the shaft axis.
US10434633B2
A disc for holding small parts to a drill, screwdriver, or other tool is disclosed. The tool has a rotating shaft, which it uses to function and the disc sits on this shaft stationary, while the shaft rotates, or, at least, rotates at a much lesser rate. The disc is also magnetic, so small parts, such as screws and other fasteners, as well as bits (e.g. drill bits and screwdriver heads) made of metal attach to the circular disc by way of magnetic force. In this manner, one can use the tool causing the shaft to rotate while holding the small parts to the circular disc situated on the shaft.
US10434623B2
A polishing module including a chuck having a substrate receiving surface and a perimeter, and one or more polishing pad assemblies positioned about the perimeter of the chuck, wherein each of the one or more polishing pad assemblies are coupled to an actuator that provides movement of the respective polishing pad assemblies in one or more of a sweep direction, a radial direction, and a oscillating mode relative to the substrate receiving surface and are limited in radial movement to about less than one-half of the radius of the chuck as measured from the perimeter of the chuck.
US10434621B2
A workpiece processing apparatus including a control unit that is provided with a storage medium on which a polishing load measured when an upper turn table is moved downward to a fixed position in a state wherein the workpiece is properly held in holding hole of the carrier is recorded in advance, calculates a difference between a polishing load measured when upper turn table is moved downward to the fixed position in a state wherein the workpiece is held in holding hole of the carrier and the polishing load recorded on the storage medium, and judges the occurrence of abnormal holding of the workpiece if the calculated difference exceeds a threshold value. As a result, it becomes possible to detect abnormal holding of a workpiece in a short time with a high degree of precision before the workpiece is processed and prevent breakages of the workpiece and the processing apparatus.
US10434611B2
A tool having a relatively ductile working end for engaging workpieces and a relatively hard non-working portion for driving the tool is disclosed, and a process for making same. The tool is formed with the material in a first state, such as by cold-working, and then only the non-working portion is heat treated to a second state. The working end is thus maintained in the ductile state while the non-working portion is hardened, thus imparting different materials performance characteristics to working end and non-working portion.
US10434607B2
A method of immobilizing a contaminant within a component includes identifying the contaminant. The component is thermally processed via a specific thermal cycle related to the contaminant. The specific thermal cycle is performed within an inert environment relative to a substrate. The specific thermal cycle is configured to effect a controlled evaporation of volatiles of the contaminant and a controlled coking of remaining contaminant.
US10434601B2
A process of welding a weld turbulator on an article includes forming a weld pool on a surface of the article using an arc welder, directing at least one beam of at least one beam welder to at least one fusion edge of the weld pool, and translating the arc welder and the beam welder in a weld direction to shape the weld pool into the weld turbulator extending in the weld direction and having the fusion edge. A turbulator welding system includes an arc welder arranged and disposed to provide an electric arc on a surface of an article to form a weld pool and at least one beam welder arranged and disposed to provide at least one beam to at least one fusion edge of the weld pool. A component includes an article having a surface and a weld turbulator on the surface of the article.
US10434600B2
Methods include directing a laser beam to a target along a scan path at a variable scan velocity and adjusting a digital modulation during movement of the laser beam along the scan path and in relation to the variable scan velocity so as to provide a fluence at the target within a predetermined fluence range along the scan path. Some methods include adjusting a width of the laser beam with a zoom beam expander. Apparatus include a laser source situated to emit a laser beam, a 3D scanner situated to receive the laser beam and to direct the laser beam along a scan path in a scanning plane at the target, and a laser source digital modulator coupled to the laser source so as to produce a fluence at the scanning plane along the scan path that is in a predetermined fluence range as the laser beam scan speed changes along the scan path.
US10434597B1
Methods of fabricating reduced weight components for apparatuses include obtaining a component including a relatively lightweight material; placing at least one stabilizing structure on the component; sequentially applying a plurality of applied layers on the component and the stabilizing structure by applying the relatively lightweight material over the component and applying over the relatively lightweight material a plurality of layers having gradually progressively higher proportions of the relatively heavyweight material than preceding ones of the plurality of layers closer to the component, with an outer layer of the plurality of applied layers including the relatively heavyweight material; diffusion bonding the plurality of applied layers by consolidation of the plurality of applied layers; and cutting component features in the plurality of applied layers.
US10434588B1
A power miter saw includes an activation assembly including a lever, a spring loaded drive rod passing through an underside of the table, a curved link pivotably secured to the drive rod, a pivotal member pivotably secured to the curved link and secured to the lever, a driven rod, a clamping member in an edge of a positioning seat, and an axle through the positioning seat and having an end pivotably disposed in a support seat; a graduated member including apertures; and a locking device including a hollow member having two side slots, a spring loaded cam member, and a transverse bar passing through the positioning seat, the slots, and the cam member; a spring loaded pin secured to a forward end of the hollow member; and two lever members secured to two ends of the transverse bar respectively. A pivotal movement of the lever unfastens a positioning seat.
US10434582B2
A tool coupling used for a clamping connection between two coupling parts, in particular between a cutting head and a carrier of a rotary tool, in particular of a drill. The coupling parts comprise clamping sections, which respectively correspond to one another and which can be clamped against each other by turning counter to a predefined direction of rotation about an axis of rotation so that a press fit is produced. In order to produce a high clamping force and at the same time allow for a simple installation via screwing in, each clamping section comprises several successive clamping surfaces which—with respect to a cross section viewed orthogonally to the axial direction—respectively travel along a circular arc, wherein the diameter increases for clamping surfaces succeeding one another in the direction of rotation.
US10434581B2
A high-speed tool holder includes: a tool shaft for accommodating a tool at its first end, and a machine clamping part which is integrally connected to the tool shaft and forms an interface for clamping in the machine; with the tool shaft being substantially truncated circular cone-shaped, a first diameter at the first end with the tool insertion opening being smaller than a fifth diameter at the second end at the machine clamping part; and a portion of the substantially truncated circular cone-shaped tool shaft having an outwardly bulging, preferably spherical, shape between the tool insertion opening and the machine clamping part.
US10434579B2
A peeling machine includes a rotating head installed rotating around an axis of rotation and provided with a central cavity. During use, an oblong product to be worked is disposed and a plurality of support sliders are installed thereon to support respective tools and a plurality of adjustment units configured to move the support sliders in a radial direction with respect to the axis of rotation. The peeling machine also includes a transmission unit configured to transmit motion from a first motor to the rotating head and to make the latter rotate, and also to transmit motion from a second motor to the adjustment units to simultaneously adjust the radial position of the tools.
US10434574B2
A gas collecting mechanism installed in the laminating and shaping apparatus has a partition section extending from a ceiling section of the chamber along a second wall surface with a predetermined interval therebetween, a first gas collecting port formed in the partition section, a suction apparatus installed in the first gas collecting port, a first gas guide space section formed between the partition section and the second wall surface, a first duct communicating with the first gas guide space section and installed on the ceiling section, a second gas collecting port formed on the ceiling section adjacent to the second wall surface, and a second duct communicating with the second gas collecting port.
US10434566B2
A casting device is provided with: a pair of cylinders; a core pin holding member to which core pins are attached; and a pair of bent members. The cylinder is disposed in parallel with a second limb of the bent member, and a rod is coupled to a surface on the inner side of a first limb of the bent member. The second limb is coupled to the core pin holding member via a coupling mechanism so as to be freely attachable to/detachable from the core pin holding member.
US10434562B2
A method is provided for connecting a first component to a second component. The first component has a deformation region, wherein the deformation region is at least partially heated in a first step. An inner die for the plastic deformation is provided in a second method step. The first component is plastically deformed in the deformation region in order to connect the first component to the second component in a third step, and wherein the deformation region is at least partially contacted by the inner die in the second step.
US10434561B2
The invention relates to a method for connecting a pipe (3) for liquid or gaseous media with a plug connector (4), wherein a first casing section (12) of the plug connector (4) is deformed by means of a pressing tool in such a way that a pipe (3) positioned between the first casing section (12) and a second casing section (15) of the plug connector (4) is clamped. During the pressing process, the pressing force applied to the pressing tool is detected and a pressing force increase per unit of path length is calculated from the travel of the pressing tool and the pressing force. The detected pressing force increase per unit of path length is compared to a minimum required pressing force increase per unit of path length, and in the event, that the determined minimum required pressing force increase per unit of path length is not met, the plug connector (4) is identified as faulty.
US10434555B2
Systems and methods for using metrology to assist a user at a workstation to form a part into a desired contour include scanning the part to obtain scanned data indicative of an actual contour of the part. Distance errors are determined based on a comparison of the scanned data to a computer model of the desired contour. A contour map of deviation is determined based on the distance errors, with the contour map of deviation indicating magnitudes of the distance errors for at least a selected set of points on the actual contour of the part. Visible indicium is projected onto the part that represents the contour map of deviation, thereby assisting the user of the workstation to identify where further modification of the actual contour is needed.
US10434553B2
A container for use in a metal extrusion press includes a mantle having an elongate axial bore therein, the bore having a first transverse axis orthogonal to a second transverse axis, and a plurality of longitudinally extending heating elements accommodated by the mantle adjacent the bore. The heating elements are individually controllable for controlling a thermal profile within the container. The container also includes a plurality of temperature sensors configured to measure the thermal profile within the container. The temperature sensors include a first temperature sensor and a second temperature sensor positioned on opposite sides of the first transverse axis, and a third temperature sensor and a fourth temperature sensor positioned on opposite sides of the second transverse axis.
US10434550B1
Techniques for testing subterranean water for one or more radioactive isotopes for a hazardous waste material repository include collecting, from a test drillhole formed from a terranean surface to a subterranean formation, a subterranean water sample from the subterranean formation; determining, with an accelerator mass spectrometry (AMS) system, a concentration of a radioactive isotope of an element in the subterranean water sample relative to a stable isotope of the element in the subterranean water sample; comparing the determined concentration of the radioactive isotope of the element in the subterranean water sample with a concentration of the radioactive isotope of the element in a surface water sample relative to the stable isotope of the element in the surface water sample; and based on the determined concentration of the radioactive isotope in the subterranean water sample being a specified percentage of the concentration of the radioactive isotope in the surface water sample, determining that the subterranean formation is a hazardous waste storage repository.
US10434544B2
Provided is a method for producing a coating that includes a surfacer coat and topcoat on a substrate and including applying a first coating material to an untreated substrate or a substrate coated with a cured electrodeposition coat, and applying a second coating material to the surfacer coat. The produced coating system is cured to form the coating. The first and second coating materials are compatible according to DIN EN ISO 12944-5:2008-01, and the second application takes place before the first coating material has reached drying stage 1 according to DIN 53150:2002-09, and the drying stage is determined according to EN ISO 9117-3:2010. The method is suitable for producing coatings on automobiles and commercial vehicles, such as trucks, vans, and buses.
US10434543B2
Herein are disclosed a pressure-sensitive adhesive layer on a substrate, the adhesive layer containing stripes of first and second pressure-sensitive adhesives. The surface of the adhesive layer that faces the substrate is surface-enriched with the first pressure-sensitive adhesive. Methods of making are disclosed.
US10434540B2
Non-conductive films for constructing lighter than air balloons are provided. A non-conductive film may comprise multiple layers of gas barrier polymers. An outer surface printable layer and an interior heat or ultrasonically sealable layer may also be included. Each gas barrier film may comprise multiple (e.g., from 3 to approximately 75) barrier layers. A gas barrier core has a nano-layer structure. A gas barrier core may also comprise a biodegradable film or a bio-based film. A non-conductive film may comprise a metal layer for enhancing gas barrier properties. The metal layer may be discontinuous. The metal layer may be conductive and coated with an insulating top coat.
US10434538B2
A dispenser system for applying multi-component adhesives or like substances to work surfaces in carpeting, roofing and like applications as well as a method of dispensing and applying multi-component adhesives to work surfaces.
US10434537B2
A method of dispensing material includes delivering an electronic substrate to a dispense position. The electronic substrate has at least two identical patterns and at least two fiducial marks. The method further includes capturing at least one image of the at least two fiducial marks provided on the electronic substrate, analyzing the at least one image to determine a position of the electronic substrate in X axis, Y axis and theta directions, calculating a rotational angle of the electronic substrate, and rotating a dispensing pump array to match an angle of the electronic substrate. Alternatively, the electronic substrate can be rotated to match an angle of the dispensing pump array.
US10434526B2
An improved mist generating apparatus is provided, the apparatus having a longitudinal axis (L), and first and second opposing nozzle surfaces (100,102) which define a nozzle between them. A first process fluid passage (28) has an inlet connectable to a supply of process fluid, and a process fluid outlet (110) on one or the first and second nozzle surfaces (100,102) such that the process fluid outlet (110) opens into the nozzle. The nozzle has a nozzle inlet (104) connectable to a supply of driving fluid, a nozzle outlet (108), and a throat portion (106) intermediate the nozzle inlet (104) and nozzle outlet (108). The nozzle throat (106) has a cross sectional area which is less than that of both the nozzle inlet (104) and the nozzle outlet (108). The nozzle extends radially away from the longitudinal axis (L) such that the nozzle defines a rotational angle about the longitudinal axis (L). A centre line (CL) of the nozzle extends from the nozzle throat (106) to the nozzle outlet (108) at an angle of between 50 and 80 degrees relative to the longitudinal axis (L).
US10434524B2
A ball joint connector is provided for linking a showerhead to a water supply pipe. The connector has an internal venturi that draws air into the connector to aerate water being provided to the showerhead. A flow control member is disposed in a fluid pathway connected to the venturi, preventing spraying or leaking out of the air inlet, while reducing noise associated with the air induction.
US10434512B2
The invention relates to a method for analysis of the AT/GC ratio of DNA by stretching the DNA in nanochannels and performing melting mapping of the AT/GC ratio along the DNA molecule.
US10434509B2
The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
US10434495B2
An object of the present invention is to provide a method for producing water absorbent resin powder in which permeability potential (SFC) is improved while a water absorbing rate (FSR) is being kept. The method is a method for producing water absorbent polyacrylic acid (salt) resin powder including the steps of: (i) polymerizing an acrylic acid (salt) monomer aqueous solution; (ii) during or after the step of (i), performing gel grinding of a hydrogel crosslinked polymer obtained by the polymerization, wherein the hydrogel crosslinked polymer has resin solid content of 10 wt % to 80 wt %, and the gel grinding is carried out with gel grinding energy (GGE) of 18 [J/g] to 60 [J/g]; (iii) drying a particulate hydrogel crosslinked polymer obtained by the gel grinding, wherein the drying is performed at 150° C. to 250° C.; and (iv) carrying out a surface treatment to the particulate hydrogel crosslinked polymer thus dried.
US10434493B2
Metal-containing sorbent materials are provided, methods of making the metal-containing sorbent materials, methods of using the metal-containing sorbent materials, and metal complex-containing composite materials resulting from the sorption of basic, nitrogen-containing compounds on the metal-containing sorbent materials are provided. The sorbent materials are prepared by incorporating divalent metals into a precursor material that is formed by treating a porous siliceous material having mesopores with a silane or disilazane surface treatment agent. The metal-containing sorbent materials can be used to capture basic, nitrogen-containing compounds having a molecular weight no greater than 150 grams/mole.
US10434485B2
The present invention generally relates to microparticles and, in particular, to systems and methods for encapsulation within microparticles. In one aspect, the present invention is generally directed to microparticles containing entities therein, where the entities contain an agent that can be released from the microparticles, e.g., via diffusion. In some cases, the agent may be released from the microparticles without disruption of the microparticles. The entities may be, for instance, polymeric particles, hydrogel particles, droplets of fluid, etc. The entities may be contained within a fluid that is, in turn, encapsulated within the microparticle. The agent may be released from the entity into the fluid, and then from the fluid through the microparticle. In such fashion, the release of agent from the microparticle may be controlled, e.g., over relatively long time scales. Other embodiments of the present invention are generally directed to methods of making such microparticles, methods of using such microparticles, microfluidic devices for making such microparticles, and the like.
US10434479B2
The present invention relates to a composite membrane for gas separation and/or nanofiltration of a feed stream solution comprising a solvent and dissolved solutes and showing preferential rejection of the solutes. The composite membrane comprises a separating layer with intrinsic microporosity. The separating layer is suitably formed by interfacial polymerization on a support membrane. Suitably, at least one of the monomers used in the interfacial polymerization reaction should possess concavity, resulting in a network polymer with interconnected nanopores and a membrane with enhanced permeability. The support membrane may be optionally impregnated with a conditioning agent and may be optionally stable in organic solvents, particularly in polar aprotic solvents. The top layer of the composite membrane is optionally capped with functional groups to change the surface chemistry. The composite membrane may be cured in the oven to enhance rejection. Finally, the composite membrane may be treated with an activating solvent prior to nanofiltration.
US10434472B2
Provided is a seawater desalination system including reverse osmosis membrane modules each including: a reverse osmosis membrane; and a pressure vessel installing the reverse osmosis membrane, and configured to obtain permeated water and concentrated water using the reverse osmosis membranes housed in the reverse osmosis membrane modules by supplying seawater to the reverse osmosis membrane modules. The seawater desalination system includes a module group including the reverse osmosis membrane modules connected together in parallel. The seawater is supplied to each of the reverse osmosis membrane modules by being supplied to the module group through first and second seawater supply routes. The first and second seawater supply routes are each provided with a liquid transport pump configured to supply the seawater flowing through the seawater supply route to the module group.
US10434470B2
The boiler (1) has side tubed walls (2) enclosing an inner space (3) and a device for selective non catalytic reduction (7). The device for selective non catalytic reduction (7) has a lance (8) carrying a hose (9) having at least a nozzle (10) and a hose drive mechanism (11) for driving the hose within the lance. The lance (8) protrudes into the inner space (3) from a side tubed wall (2) of the boiler (1).
US10434469B2
A method for integrating a carbon capture process with a process for cement production.
US10434468B2
A method of removing ammonia from a continuous vent gas stream of a urea plant, in particular of a medium-pressure section of a urea plant, includes a step of removing ammonia from the continuous vent gas stream of the urea plant using a controlled-combustion process including at least a first lean, oxygen-poor combustion step performed in the presence of an understoichiometric amount of oxygen acting as the sole comburent, and in a reducing atmosphere of hydrogen.
US10434463B2
A separation membrane for olefin separation and olefin separation method using the same are provided.
US10434453B2
A compressor system includes a compressor and a filter assembly that includes a holder and a replaceable filter element positioned via the holder. The holder is formed in part of a perforated wall such as a metallic mesh material wall, forming a cavity wherein the replaceable filter element is positioned. An end cap traps the replaceable filter element within the cavity. The holder is reusable, so as to reduce material waste and cost.
US10434447B2
A door and door closure system for an air filter cabinet are described herein. One device includes a magnet recess, a magnet coupled to the magnet recess and configured to engage with a magnet recess of a frame of an air filter cabinet and automatically align the door with the frame of the air filter cabinet when engaged with the magnet recess of the frame, and a handle adjacent the magnet recess of the door.
US10434446B2
The invention is directed to methods of providing backwash processes for a synthetic compressible medium filter system. More specifically, the system may include a backwash pump and air blower, and the processes may include at least three sequences of: air and water wash; air purge; and medium compression. The backwash process may be triggered by one or more of a pressure, time point, and/or turbidity set point. The air and water wash sequence may include breaking and washing the medium. The air purge sequence may include removing substantially all of the air entrapped in the medium by providing a backwash water flow for a period of time; and a medium compression sequence compressing the medium while avoiding exposing the medium to air, including introducing raw water and where the backwash and raw water provide enough energy to compress the medium without introduction of air into the medium.
US10434443B2
A refrigeration system includes a water circulation system and a replaceable water filter. The refrigerator includes a sensor that determines if a water filter is present, and a user interface that prompts a user to purge a water filter upon installation of a new water filter in the refrigerator. The water filter may include a memory storage device that stores information concerning the allowable life of the water filter, the remaining life of the water filter, and other information. Information concerning the remaining life of the water filter and other information can be displayed or otherwise communicated to a user by the user interface.
US10434439B2
A wirelessly controlled device for atmospheric water generation is provided. The device comprises an atmospheric water generator for generating filtered potable water and a wireless external control system. The wireless external control system comprises one or more display presentation pages for displaying a plurality of operating parameters for the atmospheric water generator, including content display with a variety of operation parameters and historical water collection data for operation of the atmospheric water generator. The wireless external control also has one or more display pages configured for user input for a user to select one or more water generation parameters for operation of the atmospheric water generator. Once the device is directed by the wireless external control system to generate water, the device is capable of automatic water generation until the device fulfills the one or more set water generation parameters.
US10434436B2
Provided is a gas-blowing vaporizing and drying device, which includes: a sample tube in the form of a double tube including an inner tube for a solution and an outer tube for a gas, the inner tube protruding from one end of the outer tube by length L; and a collection container including a container body and a lid provided with a protrusion sleeve tube, the protrusion sleeve tube including a coupling portion at an end to be located outside the container body and a sleeve portion of a length equal to or longer than L having an open end to be located inside the container body, the coupling portion being designed to be coupled to the aforementioned one end of the outer tube in an air-tight manner.
US10434423B2
Disclosed are various embodiments for preventing a patron from starting an inactive player in a fantasy sports system. An application program is executed on one or more computing devices. The application obtains information from a fantasy sports system about a patron's current roster and monitors sports players on the patron's roster to determine if any become inactive. The patron is notified if a player becomes inactive and can choose to substitute an alternative sports player.
US10434420B2
A video game includes an audio-video stream combined with game graphics and game sounds. The game graphics are overlaid on the video stream and updated in synchronization with the stream. Update of the game graphics and sounds depends on inputs received from a game player. The game player may provide input using a game controller coupled to the video game by an adapter. The video game may play on a Blu-ray player.
US10434419B2
A login processing unit performs a login process of a user. An assignment processing unit assigns an inputting device connected to an information processing apparatus to a user. An assignment processing unit controls an assignment process of the inputting device in response to the number of users who are in a login state and executes an assignment process which is different between a case in which the number of users in a login state is one and another case in which the number of users in a login state is two or more. The assignment processing unit assigns, when the number of users in a login state is one, the inputting device connected to the information processing apparatus to the one user.
US10434408B2
In an information processing apparatus of a guest user, an image data acquisition unit acquires content image data from a host user, and a reproduction processing unit reproduces the content image data and outputs the content image data from an outputting apparatus. An information acquisition unit acquires information for specifying a sharing mode of a content image, and a notification unit notifies the user of the information indicative of the mode of the sharing process in an associated relationship with the reproduced content image. Further, if the information acquisition unit acquires information indicating that the content is within a sharing restriction period, then the notification unit notifies the user of the information indicating that the content is within the sharing restriction period.
US10434404B2
Current position information of an information processing apparatus is acquired by using a positional information acquiring section, and a distance, in a real space, between a current position and a target position that is a position corresponding to a predetermined position in the real space is calculated. Then, a predetermined process based on the calculated distance is executed when a parameter value indicating a virtual movement range of a player satisfies a first condition according to the calculated distance.
US10434403B2
The present disclosure discloses an information processing method performed at a terminal including: rendering a graphical user interface of an online game system, the graphical user interface including one or more virtual characters and at least one virtual resource object; detecting a touch operation on a specific virtual resource object; identifying a configuration parameter corresponding to the specific virtual resource object, the configuration parameter including multiple preconfigured operation objects, each preconfigured operation object having an associated message; rendering, within the graphical user interface, an information interface with the preconfigured operation objects located near the specific virtual resource object; detecting a release operation on the specific virtual resource object when one operation object is rendered visually distinguishable over other operation objects in the graphical user interface; and transmitting a message associated with the visually distinguishable operation object to terminals corresponding to one or more virtual characters of the online game system.
US10434398B1
One aspect is an exemplary climbing skin extending along a longitudinal axis. For example, the skin may comprise: an attachment surface engageable with an undersurface of the snow device; a glide surface that slides across snow when moved in a forward direction along a longitudinal axis of the skin and resists sliding across the snow when moved in a rearward direction along the longitudinal axis; and a stiffener element disposed between the attachment surface and the glide surface to resist a lateral bending about the longitudinal axis and permit a longitudinal bending about a lateral axis of the skin that is generally perpendicular to the longitudinal axis.
US10434397B2
An illuminating hockey puck and hockey goal monitoring system is provided. The hockey puck comprises a standard size hockey puck with an imbedded RF receiver, electrical circuit, and a power source therein. The receiver functions in coordination with the hockey goal monitoring system, which registers when the receiver passes over its threshold to energize a light source either in the puck or along the goal itself. The monitoring system comprises a transmitter connected to an energized wire disposed within the goal posts and over the threshold of the goal, whereby the proximity of the receiver to the wire can be measured and the system registers when the puck has entered the goal.
US10434394B2
An exercise arrangement includes a movable support that is movable in a fore-aft direction and simultaneously movable laterally, e.g. about a tilt axis. The support may be a platform movably mounted to a base. A roller and track arrangement may be provided between the platform and the base, to provide movement of the platform in the axial direction relative to the base as well as an axially neutral position of the platform relative to the base. The roller and track arrangement may be in the form of one or more curved roller and track engagement surfaces that extend in the axial direction and that provide a gravity bias of the platform toward the neutral position. The roller and track arrangement may provide tilting movement of the movable platform about the tilt axis. A tilt biasing arrangement biases the platform toward a neutral tilt position relative to the base.
US10434393B2
A basketball shot training device comprising a wrist band 1; a finger piece 2 having two different size open ring holes 3, 4 for placement and securing on the user's index and middle fingers, a forked shaft portion 5 with a straight connection 6 to said open ring hole 3 for the index finger and a curved connection 7 to said open ring hole for the middle finger; and a straight shaft portion 8 connected at one end to said forked shaft portion and at the opposite end having an attachment means 9 to attach to said wrist band.
US10434385B2
A golf club head includes a face, a sole, and a weight member. The sole includes a guide groove having a plurality of positioning grooves. The weight member includes a plurality of protrusions, and is positioned in the guide groove with the plurality of protrusions engaging with the plurality of positioning grooves. The plurality of positioning grooves each include a pair of sidewalls formed in an arc shape and a bottom connecting the sidewalls to each other. The plurality of protrusions each include a pair of side surfaces formed in an arc shape and a ridge connecting the side surfaces to each other.
US10434383B2
A golf club head includes a heel portion, a toe portion, a hosel, and a striking face. The striking face includes a plurality of scorelines each having an average depth no less than about 0.10 mm, a plurality of micro-grooves each having an average depth no greater than about 0.010 mm, and a plurality of textured surface treatment regions superimposed on the micro-grooves so as to at least partially intersect the micro-grooves.
US10434380B2
A golf club head made out of multi-material is disclosed herein. More specifically, the golf club head in accordance with the present invention has at least a portion of the body of the golf club head that is further comprised out of a base layer and a lightweight cover layer. The base layer may have a plurality of cutouts to help reduce unnecessary mass and the lightweight cover layer may be made out of an ultra-lightweight material to further reduce the unnecessary mass.
US10434369B2
A system and method of using an exercise system having a resistance structure of handles connected to cables, which cables are connected to at least one pneumatic cylinder that creates resistance, wherein the resistance is adjusted by the user via actuators in the handles, so that the user does not need to release the handles to adjust the resistance. The system is typically supported by a frame to surround the user, and the pneumatic cylinder may be connected to an equalizing tank that may be housed within or integrated into the frame. The system may include a monitor to visually display system parameters and other information to the user. The system may calculate resistance and work done by the user by measuring piston displacement and speed, as well as using accelerometers or other devices integrated into the handles.
US10434368B2
A method for controlling an electric actuator in an exercise device, comprising: supplying a first load set point (FA, kA) upon a displacement of the load element in a first direction, supplying a second load set point (FB, kB) upon a displacement of the load element in a second direction, and detecting an initial position (M) of the moving part of the electric actuator when the reversal of the movement is detected, computing an end-of-transition position (N) exhibiting a deviation in the second direction relative to the initial position, supplying a transition load set point in the form of a monotonic function of the position of the moving part of the electric actuator or of the load element, said monotonic function varying from the first load set point (FA, kA) to the second load set point (FB, kB) between the initial position (M) and the end-of-transition position (N).
US10434364B2
The present invention concerns a support frame for a gymnastic apparatus, particularly for a cycling simulation device, comprising a base, and a first arm hinged with said base and a second arm hinged with said base, so that said first and second arm can assume a closed position and an open position, rotating with respect to said base, characterized in that said support frame comprises an articulation member articulated with said base and said first and second arm such that the rotation of one of said first or second arm relatively to said base causes a rotational translation of said articulation member and the rotation of the other arm with respect to said base, causing the passage from said closed position to said open position or vice versa.
US10434357B2
A therapeutic rehabilitation device utilizing two parallel independent foot pedals on one side of the device, for isolated ankle exercises, and a larger flat board on the other side of the device, large enough for two feet to rest on, for use in active assistance exercises. To use the device for active assistance rehabilitation, the user places the device on the ground with the two pedals resting on the ground. To use the device for active isolated exercise, the user flips the device over, with the flat board facing the ground, and the two pedals facing upward.
US10434355B1
Exercise equipment includes a case having first and second parts. The first part is movable relative to the second part and defines a closed state in which an interior compartment is defined and an open state in which the interior compartment is accessible. The first and second parts each have a bottom panel and at least one side panel extending from an outer edge thereof. The first part includes a pair of connection implements in or on side panels opposite one another. In a use state, a connection pin engages with the connection implements, a pneumatic cylinder connects to the connection pin and includes an extendable actuating rod, and an attachment is attachable to the actuating rod and allows a user to interact therewith to exercise. The connection pin, pneumatic cylinder, and attachment fits in the interior compartment in their storage state.
US10434351B1
It is important to allow a sore or injured muscle to recover after strenuous physical activity or trauma to an affected limb. The device has separate stations that permit all major muscle groups to be massaged or rehabilitated and each station can be operated independently of each other section. The individual sections can be detached from a triangular support member and placed at more ideal locations in the rehabilitation facility, if needed or desired. The device is not intended to replace the expertise of a trained medical provider or personal trainer but is intended to allow a person to self-direct some efforts to massage aching or sore muscles.
US10434342B2
An oxygen supply system includes a container housing having a container door, a latch controller coupled to a latch of the container door and configured to control the latch to releasably open the container door, a microcontroller coupled to the latch controller and configured to output a first latch deployment signal to the latch controller to cause the latch controller to open the latch, a pressure sensor coupled to the latch controller and configured to output a second latch deployment signal to the latch controller to cause the latch controller to open the latch, and an energy storage coupled to the microcontroller and the pressure sensor and configured to supply the microcontroller and the pressure sensor with electrical energy. The microcontroller includes built-in test equipment (BITE) configured to monitor and test the operability of one or more of the microcontroller, the latch controller, the pressure sensor and the energy storage.
US10434340B2
A method of treating skin is disclosed. The method can include topically applying to skin in need thereof, an emulsion comprising palmitoyl tetrapeptide 7, water, glycerin, cetyl alcohol, denatured alcohol, stearic acid, dimethicone, squalane, mineral oil, and beeswax.
US10434334B2
A method for irradiation based on a fluence map includes determining a shield type of each of a plurality of rows of a fluence map. The method also includes determining, for each of the plurality of rows, a movement curve indicating a relationship between an irradiation dose in the each of the plurality of rows and a moving position of a leaf pair corresponding to the each of the plurality of rows. The method further includes determining an initial irradiation dose for each of the movement curves and synchronizing one of the movement curves based on the shield types of the plurality of rows. The method also includes selecting at least one irradiation dose of at least one point on an irradiation dose axis and generating a control point according to the selected irradiation dose.
US10434330B2
A process for safely providing retinal phototherapy includes generating an interferometric signal or pattern by applying a near infrared light beam to a retinal pigment epithelium of a retina of an eye. A level or concentration of melanin within the retinal pigment epithelium of the retina is compared to a normal level or concentration using the detected interferometric signal or pattern. One or more treatment parameters of the retinal phototherapy is adjusted if the level or concentration of melanin in the retinal pigment epithelium of the eye exceeds the normal level or concentration by a predetermined amount.
US10434325B2
Disclosed are therapeutic lamp platform mobile device applications. According to an exemplary embodiment of this disclosure, provided is a phototherapy device comprising a wearable therapeutic lamp platform including a plurality of radiant lamps disposed to communicate radiant energy to a user treatment area; a power source; a controller operatively associated with the therapeutic lamp platform and the power source configured to limit a number of available doses of radiant energy provided to a user, and the controller configured to communicate with an ecommerce platform to obtain an additional number of available doses.
US10434306B2
A device for extracting an elongated implanted structure from an obstruction within a vessel of a patient includes an inner sheath assembly and an outer sheath assembly. The inner sheath assembly includes an inner sheath and a tip, each having a passageway therethrough for receiving the implanted structure. The tip is configured for cutting and/or disrupting the implanted structure from the obstruction. The outer sheath assembly includes an outer sheath and a tip, each having a passageway therethrough for receiving the inner sheath assembly. The outer surface of this tip includes a plurality of raised elements circumferentially disposed therealong. The raised elements are configured for stabilizing the tissue of the vessel as the device is advanced through the vessel.
US10434303B2
A neural stimulation system delivers neural stimulation to a target nerve with control of direction of propagation of evoked neural signals in one or more fiber types of the target nerve using electrode configuration, thereby providing effective therapy while minimizing unintended effects. In various embodiments, mechanical parameters of a multi-polar electrode are determined to provide directed propagation of the neural stimulation by effecting neural conduction block in or near the stimulation site. In various embodiments, the electrode includes a cathode for evoking action potentials and a plurality of anodes for blocking the propagation of the evoked action potentials in specified direction(s) and fiber type(s) while minimizing the formation of virtual cathodes.
US10434302B2
Electrode devices having directional electrodes for use in deep brain stimulation or other uses. In one aspect, an electrode assembly comprises an elongate lead and a lead guide that are engageable with each other in a coaxial relationship. When the elongate lead and the lead guide are engaged with each other, the two components are rotationally fixed in relation to each other. In another aspect, an elongate lead comprises a radiologically-visible feature for indicating the orientation of the elongate lead. In yet another aspect, an electrode system is capable of determining the position and/or orientation of an electrode positioned within a body. In other aspects, methods for electrically stimulating a target site in the body are disclosed.
US10434301B2
A system for electrically stimulating and/or detecting bioelectrical signals of a user comprising: an array of permeable bodies configured to absorb a solution that facilitates electrical coupling with a body region of the user; a housing defining an array of protrusions conforming to the body region and comprising: an array of channels distributed across the array of protrusions, each channel at least partially surrounding a permeable body, configured to deliver the solution to the permeable body, and comprising a barrier that prevents passage of the permeable body past the barrier, and a manifold configured to distribute the solution to the array of channels; and a coupling subsystem comprising a first electrical coupling region in electrical communication with an interior of the manifold, wherein the first electrical coupling region is configured to couple to a second electrical coupling region that couples the first electrical coupling region to the electronics subsystem.
US10434290B2
Textile balloon catheters, textile sleeves useful in balloon catheters, and methods of making balloon catheters are described. An example catheter includes an elongate shaft and a balloon movable between uninflated and inflated configurations, and a textile sleeve secured to the balloon. The textile sleeve has a plurality of warp threads and at least one weft thread extending circumferentially around the balloon. Circumferential loops in the portion of the textile sleeve that is secured to the body of the balloon are larger in diameter than circumferential loops in the portion of the textile sleeve that is secured to one or more of the proximal neck, distal neck, proximal cone and distal cone portions of the balloon.
US10434289B2
A guide wire capable of exhibiting improved penetrability for penetrating a stenosis without degradation of passing performance of the guide wire. A guide wire includes a wire main body formed into a linear shape, a distal end portion of the wire main body is formed into a curved shape by a top portion that forms an extreme distal portion and a surrounding portion that makes the top portion continuous with a peripheral surface of the wire main body, a plurality of recesses are formed in the distal end portion, and the recesses are formed in the top portion and the surrounding portion, respectively.
US10434285B2
An infusion set (101) includes a base (121), a flexible catheter (142) and an introducer needle (134). The flexible catheter (142) is movable from a first catheter position disposed substantially entirely within the base (121) to a second catheter position in which a free end of the flexible catheter (142) is disposed externally of the base (121). The introducer needle (134) is movable between a first introducer needle position disposed substantially entirely within the base (121) and a second introducer needle position in which a free end of the introducer needle (134) is disposed externally of the base (121). An activation button (161) is movable between first and second button positions. When the activation button (161) is moved from the first button position to the second button position, the flexible catheter (142) is moved from the first to the second catheter position, and the introducer needle (134) is moved from the first to the second introducer needle position to facilitate insertion of the catheter (142) and back to the first introducer needle position to store the introducer needle (134) within the base (121).
US10434280B2
The invention provides a three-channel lighting apparatus with the option to support the human circadian rhythm. By choosing especially the blue LED and green phosphor, the range of biological activity that can be changed is optimized. By adjustment of the LED spectra a bigger range in melanopsin effectiveness factor, at the same CCT range (from daylight like CCT down to dimmed halogen), can be obtained.
US10434273B2
A patient interface for delivery of a supply of pressurised air or breathable gas to an entrance of a patient's airways including: a cushion member that includes a face contacting portion, a retaining structure and a resiliently flexible lip; and a frame member, wherein the retaining structure and the frame member are repeatedly engageable with and disengageable from one another, wherein a gas chamber is formed at least in part by engagement of the cushion member and the frame member, and wherein the resiliently flexible lip is configured to provide a sealing force between the cushion member and the frame member.
US10434266B2
A nebulizer kit includes an atomizer generating an aerosol, and a particle sorting route communicating with the atomizer and sorting liquid particles in the aerosol to adjust a particle diameter distribution thereof, and guiding the aerosol to a discharge port. The particle sorting route includes a first particle sorting route with a uniform cross-sectional area in the first direction and a second particle sorting route with an inner end wall that curves from the first direction toward a second direction included in the same plane as the first direction. The first particle sorting route guides the aerosol to the second particle sorting route in the first direction, and the inner end wall of the second particle sorting route guides the aerosol in the second direction while aerosol particles with a certain particle diameter or more are attached thereto.
US10434258B2
Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.
US10434257B2
The invention relates to hand-held, powered injection devices, for administering fluids, including vaccines, to animals. The invention further relates to methods of use of the powered injection device for vaccinating avian animals. Powered injection devices according to the instant disclosure are ergonomically friendly, and offer rapid and consistent dosing, particularly for avian animals.
US10434243B2
A multi-pack assembly for containing and dispensing one or more new pen needles, and receiving and containing used pen needles after use, is provided, wherein a plurality of both new and used pen needles can be contained in a series of storage vessels, each secured to an adjacent storage vessel thereby forming an easily managed multi-pack assembly shape, and providing caps for each individual pen needle storage vessel to provide a sterility barrier and which can be opened independently of one another, and which can be closed in the same manner after use to prevent unwanted interaction with the used pen needles contained therein.
US10434241B2
A system for anal or stomal irrigation comprises a reservoir (102) for an irrigating liquid; a catheter (100) comprising a catheter tip for insertion into the rectum or stoma, a thermo sensor (128) connected to the reservoir for obtaining a measure of a temperature within the reservoir, a tubing system and/or the catheter. A control system (103) operatively connected with the thermo sensor is configured to determine a temperature within the reservoir. A method for predicting a temperature in a reservoir for irrigation liquid is also provided.
US10434240B2
Methods and systems for the treatment and post-treatment processing of a mononuclear cell product are disclosed. The methods and systems include and provide for the separation of excess conditioning fluid and unbound treating agent prior to return of said treated mononuclear cell product to a patient.
US10434238B2
The present invention relates to an extracorporeal circuit for CO2 removal from blood comprising a line for taking blood from the patient, a decarboxylation assembly and a line for returning the blood to the patient; said decarboxylation assembly comprising a first filtering unit, an oxygenator, an electrodialyzer adapted to generate an acid solution and a basic solution and means for the infusion of said acid solution upstream of said oxygenator, wherein said electrodialyzer comprises a first electrodialysis chamber and a second electrodialysis chamber, said first and second electrodialysis chambers being separated by an ionic membrane, and wherein said first chamber and said second chamber are respectively separated from the positive electrode, or anode, and from the negative electrode, or cathode, by means of a bipolar membrane.
US10434229B2
A breastpump unit for expressing human breastmilk has a breastshield for placing on a human mother's breast, a vacuum pump for generating an underpressure, and a suction line for connecting the breastshield to the vacuum pump and for transferring to the breastshield the underpressure generated by the vacuum pump. The breastpump unit also has a pressure sensor. In addition, a measuring line is present, wherein the measuring line extends from the breastshield to the pressure sensor.
US10434228B2
Systems and methods for pumping milk from a breast, wherein the milk is expressed from the breast under suction and milk is expulsed from the pumping mechanism to a collection container under positive pressure.
US10434227B2
A system for stimulating the healing of tissue comprises a porous pad positioned within a wound cavity, and an airtight dressing secured over the pad, so as to provide an airtight seal to the wound cavity. A proximal end of a conduit is connectable to the dressing. A distal end of the conduit is connectable to a negative pressure source, which may be an electric pump housed within a portable housing, or wall suction. A canister is positioned along the conduit to retain exudates suctioned from the wound site during the application of negative pressure. A controller for automated oscillation of pressure over time is provided to further enhance and stimulate the healing of an open wound. A power management motor control for varying pump drive frequency and managing a portable power supply is provided to increase battery life and improve patient mobility.
US10434224B2
A material that is less populated by biofilms than known materials and is well tolerated by the body is provided. The material is an element introducible into or attachable on a human or animal body and includes a glass and/or glass ceramic and/or ceramic material at least in some areas thereof, which inhibits the formation of biofilms and/or on which human or animal cells grow if the element is introduced into the human or animal body or attached thereto, wherein the glass and/or glass ceramic material comprises at least: SiO2 in a range from 60 to 75 wt % and ZnO in a range from 1 to 7 wt %.
US10434214B2
Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
US10434211B2
A tissue bonding article includes a flexible material, an adhesive substance applied over at least a portion of a bottom side of the flexible material, and a polymerizable adhesive composition permeated throughout at least a portion of the flexible material.
US10434202B2
A lighting device configured to deactivate pathogens in an environment. The lighting device includes a housing, means for mounting the housing to a surface in the environment, one or more first light-emitting elements arranged in the housing and configured to each produce disinfecting light having a wavelength in a first range of wavelengths, and one or more second light-emitting elements arranged in the housing and configured to each produce disinfecting light having a wavelength in a second range of wavelengths different from the first range of wavelengths. The disinfecting light produced by the first light-emitting elements and the disinfecting light produced by the second light-emitting elements mix to form a combined light, the combined light being visible light other than white light.
US10434201B2
The invention provides a method for continuous virus inactivation. The product stream is segmented by introducing a separating medium which is immiscible with the product stream and the segmented product stream is transported into a reactor 1 as detention segment under virus-inactivating conditions for the required detention time.
US10434186B2
The invention relates to chemical compounds and complexes that can be used in therapeutic and diagnostic applications.
US10434181B2
The invention relates to (among other things) oligomer-containing benzamide-based compound compounds. A compound of the invention exhibits one or more advantages over corresponding compounds lacking the oligomer.
US10434180B2
The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
US10434173B2
Novel compositions derived from antigen-binding sites of immunoglobulins having affinity for IL-31 are provided. The compositions exhibit immunological binding properties of antibody molecules capable of binding specifically to a human IL-31. CDR regions derived from same or different immunoglobulin moieties are provided. Also provided are single chain polypeptides wherein VH and VL domains are attached. The sFv molecules can include ancillary polypeptide moieties which can be bioactive, or which provide a site of attachment for other useful moieties. The compositions are useful in specific binding assays, affinity purification schemes, drug or toxin targeting, imaging, and genetic or immunological therapeutics for inflammatory diseases. The invention thus provides novel polypeptides, the DNAs encoding those polypeptides, expression cassettes comprising those DNAs, and methods of inducing the production of the polypeptides. The invention further provides the amino acid sequences of the variable regions of the monoclonal antibodies and use of these monoclonal antibody or antibody fragment in conjunction with an human IgG4 Fc molecule.
US10434161B2
Attenuated vaccines to protect vertebrate animals and people against tick-born rickettsial, Ehrlichia and Anaplasma species infections is disclosed. Also disclosed are methods to modify the organism to achieve the desired immunity through the modification of a novel genetic region involved in pathogenesis. These compounds represent a needed vaccine against an organism causing life-threatening febrile illness in humans and animals, and also represent the potential to develop new classes of drugs targeting the gene products of genes Ech_0660, Ech_0379, and Ech_0230, and their homologs of other related rickettsial pathogens.
US10434158B2
The present invention relates to a vaccine/inhibitor combination comprising an RNA vaccine comprising at least one RNA comprising at least one open reading frame (ORF) coding for at least one antigen and a composition comprising at least one PD-1 pathway inhibitor, preferably directed against PD-1 receptor or its ligands PD-L1 and PD-L2. The present invention furthermore relates to a pharmaceutical composition and a kit of parts comprising the components of such a vaccine/inhibitor combination. Additionally the present invention relates to medical use of such a vaccine/inhibitor combination, the pharmaceutical composition and the kit of parts comprising such a vaccine/inhibitor combination, particularly for the prevention or treatment of tumor or cancer diseases or infectious diseases. Furthermore, the present invention relates to the use of an RNA vaccine in therapy in combination with a PD-1 pathway inhibitor and to the use of a PD-1 pathway inhibitor in therapy in combination with an RNA vaccine.
US10434153B1
Modified T-cells have paratopes against human TK1 epitopes, are made by producing monoclonal antibodies that are specific to TK1, creating chimeric antigen receptors (CARs) by fusion of the single-chain variable fragments (scFv) of the monoclonal antibodies to T-cell signalling domains, and transducing the CARs to the T-cells.
US10434147B2
A pharmaceutical combination for use in glycemic control in a type 2 diabetes mellitus patient, said combination comprising (i) lixisenatide or/and a pharmaceutically acceptable salt thereof, (ii) insulin glargine or/and a pharmaceutically acceptable salt thereof, and (iii) optionally metformin or/and a pharmaceutically acceptable salt thereof.
US10434145B2
Provided is a method for treating a peripheral nervous system damage or injury, or for regenerating peripheral nervous system tissue that involves administering to a subject in need thereof a vector that comprises polynucleotide sequences that encode a modified vascular endothelia growth factor (VEGF) and a fibroblast growth factor (FGF2) and further a polynucleotide that encodes resistance to kanamycin. A gene-therapeutic structure encoding modified vascular endothelial growth factors (VEGF) and (FGF-2) is also provided. The gene-therapeutic structure can be administered directly to a damaged nerve and paraneural tissues both in intraoperative and post-operative period to stimulate peripheral nerve regeneration. The structure and method significantly advance existing methods for reconstructive treatment for damaged peripheral nerves.
US10434141B2
Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
US10434132B2
The present invention is related to a galactolipids-enriched plant extract, prepared by extracting a plant sample selected from a group consisting of: Gynura divaricata subsp. formosana (Asteraceae) (GD), Murdannia bracteata (C. B. Clarke) J. K. Morton ex D. Y. Hong (Commelinaceae) (MB), and Crassocephalum rabens S. Moore (Asteraceae) (CR) with a series of solvents. A pharmaceutical, nutritional, or healthcare composition for protecting or treating acute fulminant hepatitis, for protecting or treating sepsis or related indication thereof, and a composition for skin whitening are also provided herein. These compositions all comprise effective amounts of the galactolipids-enriched plant extracts or purified compounds thereof as bioactive ingredients.
US10434123B2
A two stage reaction platform is provided to produce a pollen-based extract material, comprising the steps of a first stage including: opening and/or germinating pollen grains, reacting the treated pollen grains with one or more beehive components, selected from beeswax, honey, or enzyme-containing material, and stirring to form a jelly; and a second stage including heating the jelly in a closed container to product an extract. The extract may be a fermented extract. An aqueous skin cream includes the pollen-based extract and one or more of glycerine, natural oils, emollients, preservatives, vitamins, fragrance, emulsifiers, or waxes. The skin cream may be used for treatment of skin conditions or inflammation. In another embodiment a method of treating eczema or psoriasis is provided, comprising administering to the individual in need of such treatment a therapeutically effective amount of an aqueous skin cream.
US10434122B2
A method of preparing a transplant site for cellular transplantation in a mammal includes the steps of inserting a foreign body comprising a biomaterial into an internal tissue; and removing the foreign body after the tissue surrounding the foreign body has undergone an inflammatory response but before significant fibrous encapsulation has occurred, leaving a neovascularized lumen suitable to receive transplanted cells or islets.
US10434121B2
A method of treating a subject in need of a non-syngeneic cell or tissue graft is disclosed. The method comprising: (a) transplanting into a subject a dose of T cell depleted immature hematopoetic cells, wherein the T cell depleted immature hematopoetic cells comprise less than 5×105 CD3+ T cells per kilogram body weight of the subject, and wherein the dose comprises at least about 5×106 CD34+ cells per kilogram body weight of the subject, and wherein the T cell depleted immature hematopoetic cells are obtained by separating the T cells from the immature hematopoetic cells by magnetic cell sorting, and (b) administering to the subject a therapeutically effective amount of cyclophosphamide, wherein the therapeutically effective amount comprises 25-200 mg per body weight, thereby treating the subject.
US10434119B2
A storage stable package is provided that includes a polymeric bottle having a volume filled with an aqueous saline composition acidified with an acid to a pH of 2 to 9 and having a hypertonic saline concentration relative to saliva and blood, or an aqueous hydrogen peroxide composition acidified with an acid to a pH of 2.7 to 5.3 and having a hydrogen peroxide concentration 0.5 to 3 total weight percent, either to achieve a storage stability at 20 degrees Celsius of the composition of at least 10 weeks. The aqueous composition is independent of a synthetic antimicrobial. A cap is provided that is complementary a package opening for selectively sealing the aqueous saline composition within the volume. A process for treating an infection of a pharyngeal or buccal cavity is provided that includes rinsing with one of the aqueous saline composition. The aqueous saline composition is then expectorated.
US10434109B2
The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorders, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury.
US10434107B2
Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
US10434106B2
Oxysterol-statin compounds and methods of synthesizing the same are provided for use in promoting osteogenesis, osteoinduction andior osteoconduction. Methods of synthesizing in a single container OXY133-statin compounds having high yields and improved process safety are also provided. Methods for synthesizing OXY133-statin compounds that are stereoselective are also provided. Methods of synthesizing OXY133-statin conjugates that have low production costs are provided.
US10434103B2
An object of the present invention is to provide a crystal of (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-pyrrolidinyl)-2-propen-1-one, which is useful as an antitumor agent, the crystal being stable, excellent in oral absorbability, highly chemically pure, and suitable for mass production. The present invention provides a crystal of (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-pyrrolidinyl)-2-propen-1-one that exhibits an X-ray powder diffraction spectrum containing at least three characteristic peaks at diffraction angles (2θ±0.2°) selected from 9.5°, 14.3°, 16.7°, 19.1°, 20.8°, 21.9°, and 25.2°. The present invention also provides a crystal of (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-pyrrolidinyl)-2-propen-1-one that exhibits an X-ray powder diffraction spectrum containing at least seven characteristic peaks at diffraction angles (2θ±0.2°) selected from 13.5°, 17.9°, 19.5°, 20.6°, 22.0°, 22.6°, 23.3°, 23.7°, and 24.2°.
US10434101B2
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
US10434098B2
Provided are a deuterium-substituted dehydrophenylahistin-like compound, preparation method thereof and use in a preparation of antitumor drugs. The deuterium-substituted dehydrophenylahistin-like compound has a structure of general formula (I), and a synthesis method thereof comprises: firstly conducting a condensation reaction of diacetyldiketopiperazine and an aldehyde intermediate a or a deuterated aldehyde compound b to form a heterocyclic compound c or a deuterium-containing heterocyclic compound d, which is then subjected to a condensation reaction with benzaldehyde and a deuterium-substituted benzaldehyde-like compound to form the deuterium-substituted dehydrophenylahistin-like compound. Also provided are a highly effective deuterated aldehyde intermediate with a high deuterium substitution rate and a deuterium-containing heterocycle intermediate, and a synthesis method thereof. An experiment shows that the deuterium-substituted dehydrophenylahistin-like compound provided by the present invention has an effect on tubulin depolymerization and can treat a refractory solid tumor or lymphoma. The present invention provides a method for researching and developing antitumor drugs of the related compound.
US10434096B2
Disclosed are imidazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, Y and Z are as described herein. In certain embodiments, a compound disclosed herein inhibits a cellular TAM receptor, and can be used to treat disease mediated by or involving the TAM receptor family.
US10434086B2
Provided herein are methods and compositions that relate to, inter alia, CBL0137, a carbazole compound 1,1′-[9-[2-[(1-methylethyl)amino]ethyl]-9H-carbazole-3,6-diyl]bis-ethanone, useful for the treatment of various cancers, optionally in combination with various agents.
US10434080B2
The invention provides methods for increasing oral osteogenesis using LXA4 and its analogs. Methods are also provided for treating or preventing oral disorders that would benefit from increased oral osteogenesis using LXA4 and its analogs.
US10434078B2
In certain embodiments methods are provided for the therapeutic or prophylactic amelioration of one or more symptoms or disorders associated with metabolic syndrome. In various embodiments the methods involve administering to a subject in need thereof, a GABA receptor agonist, in an amount sufficient to ameliorate said one or more symptoms. In certain embodiments methods are provided for the prophylaxis or treatment of type I diabetes and related pathologies that involve the use of GABA or GABA agonists in combination with certain other compounds (e.g., one more antigens (e.g., GAD) that have a therapeutic effect in type I diabetes and/or an anti-CD3 antibody, an anti-CD20 antibody, exendin-4, and/or or a pro-insulin therapeutic).
US10434076B2
The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or prophylactic treatment of, inter alia, dermatitis.
US10434074B2
Methods and compositions for activating an EphA receptor can be used for identifying therapeutic agents for cancer.
US10434071B2
The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.
US10434070B2
The present invention relates to methods, combinations and pharmaceutical compositions for supplying a blood source from a donor source with a mis-matched blood type, or potentially a mis-matched blood type, to a recipient, using, inter alia, an effective amount of a nanoparticle comprising a) an inner core comprising a non-cellular material, and b) an outer surface comprising a cellular membrane derived from a red blood cell, the cellular membrane of the nanoparticle comprising a blood type antigen that exists on the red blood cell from the donor source, but is missing or potentially missing on red blood cells of the recipient.
US10434067B2
Provided are a solid composite formulation for oral administration, the solid composite formulation including: an ezetimibe granules-part including ezetimibe, said ezetimibe having a particle size distribution wherein the average particle size d(0.9) for the bottom 90% is about 10 μm or less; and a rosuvastatin mixture-part including rosuvastatin or a pharmaceutically acceptable salt thereof, and a method of preparing the composite formulation.
US10434061B2
A composition and method for administering an active agent to a pet, such as a dog, a cat or a horse. The composition may comprise a yogurt-based chewable delivery matrix and a plurality of water-soluble film pieces dispersed throughout the chewable delivery matrix. The composition may also comprise a delivery matrix having at least 15% by weight of crude protein and a plurality of water-soluble film pieces dispersed throughout the delivery matrix. The plurality of water-soluble film pieces encompass an active agent therein, wherein the active agent is rapidly released from the composition upon contact with saliva from the pet. At least a portion of the released active agents may be oromucosally absorbed by the pet.
US10434060B2
A solid dose for insertion into the skin of a patient wherein the solid dose has a hollow core. There is also provided a solid dose carrier, a device, a method of manufacturing the solid dose and a method of delivering a solid dose transdermally to a human or animal.
US10434055B1
Disclosed is a modeling composition containing coconut oil having a moisturizing effect on the skin and exhibiting efficacy on atopic skin, the modeling composition further containing squalane, starch, an emulsifier, and ozokerite, in addition to coconut oil.
US10434052B2
The present disclosure relates to compounds having the following structure: or a dermatologically acceptable salt thereof, and cosmetic or dermopharmaceutical compositions comprising the same, and methods for using the compounds or compositions for treating, protecting, and/or improving the condition and/or aesthetic appearance of skin, for example, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, or improving the appearance of fine lines and/or or wrinkles of skin comprising application of the compounds or compositions disclosed.
US10434044B2
A microcapsule composition comprising at least one polymer substantially disposed as a semi-permeable shell around a buffered solution and at least one therapeutic agent, wherein the therapeutic agent permeates the shell, and wherein the composition is suitable for delivery to a mammal. This invention also provides related compositions, products and methods.
US10434028B2
A step aid device has a series of support structures positioned on a flight of stairs to assist a user with a lower leg injury to climb the stairs. A first support structure may be disposed on a first plane. The first support structure has a first side, a second side oppositely disposed from the first side, and a perimeter disposed between the first side and the second side. A second support structure may be disposed on a second plane. The second support structure has a first side, a second side oppositely disposed from the first side, and a perimeter disposed between the first side and the second side. The second support structure the second plane may be offset from the first plane.
US10434025B1
A center panel for a casket includes a backing panel, a pad, and a blackout panel. The backing panel includes a backing surface. The pad includes a lower pad surface and an upper pad surface. The lower pad surface is disposed on and is attached to the backing surface. The pad has a pad color or is configured to change to the pad color. The blackout panel includes a lower panel surface disposed on and attached to the upper pad surface, and has a first opacity that obstructs visibility of the pad color of the pad. The blackout panel also has a color that is lighter than the pad color. The backing panel, pad and blackout panel collectively have a shape and size configured to cover the area between decorative edge pieces of a casket lid.
US10434023B1
A wheelchair includes a removable seat assembly that slides laterally sideways to either side of the wheelchair for assisting a seated wheelchair occupant onto a receiving seat, such as a vehicle seat.
US10434018B2
A disposable absorbent article is provided having an absorbent core located in a chassis and including absorbent particulate polymer material defining at least one cavity for improved isolation of fecal matter or other body exudates. The absorbent core may be substantially cellulose free. Methods for making such an absorbent core and corresponding disposable absorbent article are also disclosed.
US10434017B2
A method of making an elastic composite is described that entails conveying a first sheet of material on a conveyor, and wrapping a section of elastic about the first sheet and the conveyor, thereby applying elastics cross directionally across the first sheets. A second sheet of material is applied onto the first sheet having elastics applied thereon, thereby creating a subcomposite including the first sheet, the second sheet, and elastics sandwiched therebetween, wherein a plurality of elastics extend outward from the one side of the subcomposite, about the conveyor, and return into an opposite side of the subcomposite. The sub-composite is cut through the first and second sheets and the elastics, thereby separating the sub-composite into a first carrier and a second carrier, each carrier including a first material layer and a second material layer, whereby a plurality of spaced apart elastic elements extend from the first carrier to the second carrier, the first and second carriers defining an exposed elastic region therebetween formed by the plurality of spaced apart elastic elements.
US10434015B2
Provided are buffered adhesive compositions comprising a high molecular weight non-neutralized polymeric acid and a high molecular weight partially neutralized polymeric acid and products such as wound dressings and ostomy skin barriers incorporating the compositions.
US10434014B2
A treatment system including one or more of a wound dressing having one or more of a substrate element, a dressing member disposed on the substrate element, an adhesive element disposed on the substrate element, and a tether connecting the wound dressing to a treatment device.
US10434011B2
A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.
US10434006B2
A method and apparatus for the treatment of OSA are disclosed which protrudes the tongue and hence enlarges the pharyngeal cross-sectional area by implanting a state changing actuator, one leg inserted helically directly into the root of the tongue near the hyoid bone, along and near the base of the tongue into the body of the tongue, the section leaving the root of the tongue providing a torque (tending to expand the V-shape of the implant), the other leg acting as a force distribution placed between the root of the tongue and the geniohyoid, or between geniohyoid and mylohyoid. Another embodiment shows placement of a passive implant to permanently compress the tongue by deforming it providing a force compressing the tongue, the force directed toward the axis of the helix, hence protruding the tongue to enlarge the pharyngeal cross-sectional passageway to prevent obstructions of the airway.
US10433998B2
Devices and methods of endolumenal formation of gastric sleeves are described. Some embodiments allow templating of a gastric sleeve by a gastric bougie, exposing a selected amount of tissue for suturing access, while maintaining sufficient internal working space for suturing within the template lumen.
US10433992B2
An implant delivery system has one or more interlock assemblies which connect the implant delivery catheter to the implant, an improved inner tubular member and an outer tubular member. The interlock assemblies, improved inner tubular member and outer tubular member cooperate to place the implant in tension during deployment, thereby reducing implant deployment force.
US10433987B2
Preferred embodiments of a stent with a high degree of flexibility are shown and described. The stent can include a continuous helical winding having interconnected struts joined at vertices, and having bridges connecting sections of the helical winding to each other. An annular ring can be provided at one or both ends of the helical winding, and the annular ring can have extensions extending to connect to the helical winding. One of the extensions can connect to a bridge and another extension can connect to a vertex. The struts at the ends of the helical winding can have strut lengths that differ from the strut lengths of the struts in a central portion of the winding between the ends of the winding.
US10433980B2
A device and methods for intervertebral spinal fusion of adjacent intervertebral bodies. An intervertebral spacer is positioned within a narrow disc space between adjacent intervertebral bodies of a patient. The spacer is arranged with upper and lower guides. The guides are adapted to simultaneously guide the deployment of upper and lower anchors of an anchoring device into their respective intervertebral bodies. The spacer is also adapted to lock the upper and lower anchors to the spacer in the deployed position.
US10433969B2
A system for long bone arthroplasty includes humeral head prosthesis components, and an array of humeral head prosthesis components, each humeral head prosthesis component in the array having a convex articulation surface that is hemi-elliptical and defined by a major axis, a minor axis, an apex, and a base having an elliptical cross sectional shape defined by a major diameter along the major axis and a minor diameter along the minor axis, wherein the array of elliptical humeral head prosthesis components provides for suitable and sufficient anatomical fit within a variation of up to and not more than 3 mm in at least 96% of a patient population, and up to 99% of a patient population.
US10433967B2
A modular shoulder prosthesis is provided. The modular prosthesis includes a stem, an anatomic insert, and a reverse insert. The stem is a unitary body that includes a distal shaft portion and a proximal portion. The proximal portion includes a stem face configured to directly couple to both the anatomic insert and reverse insert. The stem face includes a first engagement feature configured to couple directly to the reverse insert and a second engagement feature configured to couple directly to the anatomic insert. The stem can also include a metaphyseal portion between the shaft portion and proximal portion designed for use in humeral fracture repair procedures. The metaphyseal portion can include a medial arm and two lateral arms extending between the shaft portion and proximal portion, A window can be defined between the medial arm and the lateral arms, and a gap can be formed between the lateral arms.
US10433964B2
A joint prosthesis system is suitable for cementless fixation. The system has two metal implant components and a bearing. One of the metal implant components has an articulation surface for articulation with the bearing. The other metal implant component has a mounting surface for supporting the bearing. One of the metal implant components includes a solid metal portion and a porous metal portion. The porous metal portion has surfaces with different characteristics, such as roughness, to improve bone fixation, ease removal of the implant component in a revision surgery, reduce soft tissue irritation, improve the strength of a sintered bond between the solid and porous metal portions, or reduce or eliminate the possibility of blood traveling through the porous metal portion into the joint space. A method of making the joint prosthesis is also disclosed. The invention may also be applied to discrete porous metal implant components, such as augment.
US10433961B2
Delivery systems with tethers for prosthetic heart valve devices and associated methods are disclosed herein. A delivery system configured in accordance with embodiments of the present technology can include, for example, an elongated catheter body, a capsule carried by the elongated catheter body and carrying a prosthetic heart valve device, and a cinching member slidably disposed within the capsule. The delivery system can further include a plurality of tether elements coupled to the prosthetic device and extending through the cinching member and the catheter body. Retraction of the tether elements can urge at least a portion of the prosthetic device into a distal end portion of the cinching member to resheathe at least a portion of the prosthetic device and allow repositioning of the prosthetic device relative to the native valve after a portion of the prosthetic device has contacted tissue of a native valve.
US10433956B2
Apparatus and methods are provided including a mitral valve prosthesis. The prosthesis includes an inner support structure having downstream and upstream sections, the upstream section having a cross-sectional area greater than the downstream section. The inner support structure is configured to be positioned on an atrial side of the native valve complex, and to prevent the prosthesis from being dislodged into the left ventricle. A prosthetic valve having prosthetic valve leaflets is coupled to the inner support structure. An outer support structure has engagement arms, downstream ends of the engagement arms being coupled to the inner support structure. The prosthesis is configured such that, upon implantation thereof: downstream ends of the native valve leaflets, downstream ends of the engagement arms, and downstream ends of the prosthetic leaflets, are disposed at a longitudinal distance from one another of less than 3 mm. Other embodiments are also described.
US10433950B2
An intraocular lens adapted to be implanted inside a capsular bag, comprising a peripheral portion comprising an anterior annular portion adapted to engage an anterior capsule portion, the anterior annular portion defining an anterior opening through which an optical axis passes, a posterior annular portion adapted to engage a posterior capsule portion, the anterior and posterior annular portions being adapted to keep the capsular bag open after implantation, and an optic portion disposed within the anterior opening and secured to and radially inward relative to the peripheral portion.
US10433946B2
A catheter device for transvascular delivery of a medical device to a cardiac valve region of a patient comprises an elongate sheath with a first lumen, a distal end for positioning at a heart valve, a second lumen that extends parallel to or in the sheath, and an expandable embolic protection filter. The filter is arranged to extend from an orifice of the second lumen and, in the expanded, covers ostia of the side branch vessels in the aortic arch.
US10433944B2
The package (1) for a surgical mesh (100) comprises: a receiving member (2) configured and dimensioned to receive at least one surgical mesh (100), and a covering member (3) configured and dimensioned to cover the said at least one surgical mesh (100) maintaining with the receiving member (2) the surgical mesh (100) in a substantially flat position, and a gas channelling network interposed between the said receiving member (2) and the said covering member (3) configured to channel a sterilization gas within the at least one surgical mesh (100).
US10433940B2
The present invention relates to a toothbrush and provides an electric toothbrush comprising a hollow hand-held casing; the hand-held casing is disposed therein with a rechargeable lithium battery via a battery mount, and a brushless motor via a motor mount. The battery mount accommodates a PCT connected with the rechargeable lithium battery. The PCB is disposed with a control switch via a waterproof mount and a waterproof switch case. The press portion of the control switch is exposed from the switch hole of the hand-held casing. The vibration shaft of the brushless motor passes through the motor mount to an exterior of the hand-held casing. The vibration shaft is connected to a toothbrush head. The hand-held casing is threadedly connected to the rear cap at a bottom end thereof. The hand-held casing has a cross section in shape of a circle.
US10433937B2
A magic threader for a dental implant is disclosed, particularly, a dental implant capable of increasing coupling strength under a stable structure by specifying thickness of a thread portion, and pitch between thread portions in consideration of a difference in strength between titanium and bone to decrease stress of an alveolar bone by the thread portion and prevent damage to the alveolar bone and is capable of conducting compression of the thread portion for the alveolar bone in only one direction (direction A), minimizing compression of the thread portion for the alveolar bone in a direction B or a direction C inclined with respect to direction A, and maximizing stress dispersion by configuring the thread portion in a rectangular plate shape and specifying an angle of the screw thread in a specific numerical range.
US10433932B2
A distalizer including a mesial element and a distal element, and an arm connecting the distal element with the mesial element. The arm includes a ball member at one end and the distal element includes a receptacle for receiving the ball member. A method includes providing the distal element with an opening into the receptacle that is large enough to introduce the ball member substantially without deformation, introducing the ball member into the receptacle, and reducing the opening of the receptacle.
US10433930B2
A cradle, assembly, system and method for installing a prosthesis at a surgical site. The cradle temporarily engages the prosthesis and holds it in the correct orientation and position adjacent the surgical site. An aperture is defined in the cradle and a portion of the prosthesis is received therein. In one embodiment, the cradle, assembly and system are used to install a final dental prosthesis in a patient's mouth in a single visit to the dentist's office. A securement member pins the surgical template and subsequently the cradle to the jaw. A metal sub-structure on the final dental prosthesis is received in the aperture in the cradle. Cylinders attached to implants anchored in the jaw extend through holes in the sub-structure and are bonded to the prosthesis. The cradle is detached from the jaw and from the prosthesis prior to screws being re-inserted through the cylinders and into the implants.
US10433929B2
A method for registering a catheter navigation system to a three-dimensional image generally includes obtaining a three-dimensional image including position information for a plurality of surface points on a part of a patient's body, using a catheter navigation system to place a tool at a location on the surface of the patient's body, measuring position information for the surface location, identifying a corresponding location on the image, associating position information for the surface location and the location identified on the image as a fiducial pair, and using at least one fiducial pair to generate a mapping function. The mapping function transforms points within the coordinate system of the catheter navigation to the coordinate system of the three-dimensional image such that, for each fiducial pair, the mapping error is about zero. Suitable warping algorithms include thin plate splines, mean value coordinates, and radial basis function networks.
US10433928B2
An improved injector needle apparatus is described with inherent properties for increasing linear flow rates when inserted into a subcutaneous port during tissue expansion thus decreasing procedure time.
US10433918B2
A surgical instrument assembly disclosed herein can comprise an end effector configured to capture tissue, an electric motor couplable with a power supply, and a rotatable drive shaft operably coupled with the electric motor, wherein the rotatable drive shaft is configured to drive a firing drive during a firing stroke. The surgical instrument assembly can further comprise a sensing system configured to detect the load applied to the firing drive at the initiation of the firing stroke. The surgical instrument assembly can also comprise a lockout circuit configured to sense the current through the electric motor and to interrupt the current through the electric motor based on the sensed current at the initiation of the firing stroke.
US10433917B2
Medical software tools platform utilizes a surgical display to provide access to specific medical software tools, such as medically-oriented applications or widgets, that can assist those in the operating room, such as a surgeon or surgical team, with a surgery. In particular, an optical sensor located within an endoscopic camera may register the momentary change in the optical characteristics reflected from a tissue surface and in turn transmit the information to a medical image processing system which can also receive patient heart rate data and display relevant anomalies. Changes in various spectral components and the speed at which they change in relation to a source of stimulus (heartbeat, etc.) may indicate the arrival of blood, contrast agents or oxygen absorption. Combinations of these may indicate various states of differing disease or margins of tumors, and so forth. Also, changes in temperatures and the speed of change may indicate subsurface anomalies.
US10433916B2
System and method for determining the position and orientation (P&O) of a tool-tip relative to an eye tissue of interest. The system includes and imaging and tracking module coupled with a processor. The imaging and tracking module at least includes an imager. The imager acquires at least one image of at least one tissue-reference-marker. The imaging and tracking module further determines information relating to the P&O of the tool. The processor determines the P&O of the tissue-reference-marker according to the acquired image of the tissue-reference-marker. The processor determines the P&O of the eye tissue of interest, according to the P&O of the tissue-reference-marker, and a predetermined relative P&O between the tissue-reference-marker and the eye tissue of interest. The processor also determines the P&O of a tool-tip according to a tool-marker and determines the relative P&O between the tool-tip and the eye tissue of interest.
US10433911B2
Enhanced targeting systems and methods may be used to visualize trajectories for surgical instruments. Such a targeting system may have a first light source and a second light source. The first light source may project first light along a first plane, and the second light source may project second light along a second plane nonparallel to the first plane. At an intersection of the first and second planes, the first light and the second light may cooperate to produce a targeting line that indicates the desired trajectory. An image capture system may also be used to capture image data of anatomical features of a patient at one or more locations in space, and a controller may receive the image data and indicate the trajectory relative to the anatomical features of the patient.
US10433910B2
Provided and described herein are exemplary embodiments of apparatus, system, computer-accessible medium, procedure and method according to the present disclosure which can be used for providing laser steering and focusing for e.g., incision, excision and/or ablation of tissue in minimally-invasive surgery. For example, an exemplary apparatus is provided that can include at least one optical element which can be configured to refract and/or diffract light provided in a structure which can be configured to be inserted into a body, where at least one of the optical element(s) is structured to receive the light at a first angle and generate a refracted and/or diffracted light at a second angle which can be different from the first angle relative to an optical axis. According to a particular exemplary embodiment of the present disclosure an exemplary actuating arrangement can be provided, which can be configured to control the optical element(s), can be provided and seated at least partially within the at least one structure.
US10433898B2
An electrosurgical electrode comprises an elongated body having a cross-sectional area and longitudinal side edges forming longitudinal cutting edges adapted for electrosurgical dissection along a plane. The body has a configuration, wherein: the thickness of the side edge is less than or equal to 0.01″, forming only one cutting edge, and the cross-sectional area-to-number of cutting edges ratio is less than or equal to 0.000150 in2 per cutting edge; or the thickness of a first side edge is greater than 0.01″ and the thickness of a second side edge is less than or equal to 0.01″, and the cross-sectional area-to-number of cutting edges ratio is less than or equal to 0.001 in2 per cutting edge.
US10433894B2
A system and kit for using a source of low-pressure refrigerant for a cryotherapy procedure and for subcooling a cryotherapy refrigerant. The system may generally include a fluid reservoir and a fluid flow path in thermal exchange with the fluid reservoir, the fluid flow path including a first thermal exchange device in thermal exchange with the fluid reservoir, a compressor in fluid communication with the first thermal exchange device, a condenser, a reversing valve located between the compressor and the condenser, a second thermal exchange device located between the reversing valve and the compressor, and an expansion valve located between the condenser and the thermal exchange device. The third thermal exchange device may be configured to be in fluid communication with the cryotherapy console and configured to place a secondary refrigerant within the first fluid flow path in thermal communication with a secondary refrigerant of the cryotherapy system.
US10433892B2
Provided is a material for preventing bone cement from leaking out from bone during packing of the bone cement into a bone fracture site. The bone cement can be prevented from leaking out from the bone by employing a three-dimensional structure produced from a material containing a polyhydroxyalkanoate, when packing the bone cement into the bone fracture site.
US10433891B2
An apparatus for anchoring cable to bone includes an anchor configured to be anchored in a bone and a cable fixed to the anchor. The cable is configured to be tensioned to a measurable and adjustable tension to cause a measurable and adjustable compression of the bone by the cable. The apparatus may include a cable housing having a proximal portion, a distal portion, and a passage. The distal portion is detachably and co-rotatably engageable with the anchor and the passage is open to and extends from a distal end of the distal portion. The apparatus also includes a cable having a fixed-end portion and a free-end portion. The fixed-end portion of the cable is fixed to the anchor and the free-end portion of the cable is non-fixedly positionable in the passage of the cable housing.
US10433878B2
The present invention relates to an implantable device (40), in particular to correct at least one vertebral level, comprising a rod having an outer radius (Rt) and a circumference determined at an area on a length (Lt); an elongate flat ligament; and a securing devices (50) of said elongate element in a partial encasing position of said area comprising first (51) and second (52) forks first general partly annular shape of inner radius, respectively, and comprising partly annular lower bearing surfaces respectively delimiting first (51b) and second (52b) circumference portions greater than half the circumference. Said securing devices (50) further comprises a shoulder part arranged relative to said lower bearing surfaces (51a, 52a) of the first and second forks (51, 52) so as to form a passage for said elongate element in said encasing position between said forks (51, 52) and said shoulder part (60).
US10433870B2
An operator advances a delivery catheter through a guiding catheter, after positioning an inflatable sleeve of the guiding catheter in proximity to a target implant site on an epicardial surface. By inflating the positioned sleeve, the operator displaces the epicardial surface to create a gap that accommodates a reach of the delivery catheter. With the delivery catheter extending distally from the guiding catheter, the operator can activate the reach of the delivery catheter within the gap, and then advance the lead out through a distal-most opening of the delivery catheter. The reach may orient a fixation member of the advanced lead relative to the epicardial surface so the operator can secure the lead to the surface. The sleeve of the guiding catheter is preferably non-compliant and has a maximum diameter of at least twice the reach of the delivery catheter, when inflated.
US10433865B2
An ultrasonic surgical instrument including a wavequide extending along a longitudinal axis and an ultrasonic blade is disclosed. The ultrasonic blade includes a proximal end coupled to the waveguide, a distal end movable relative to the longitudinal axis in accordance with ultrasonic vibrations applied to the wavequide, and a tissue treatment region including a coated portion and an uncoated portion. The coated portion includes a distal-facing surface.
US10433862B2
A slotted cannula for endoscopic surgical procedures is disclosed. The slotted cannula has a tubular body having a distal end, a proximate end, an open slot extending longitudinally from the beginning of the proximate end to the proximity of the distal end, and a pair of wings integrally formed on the proximate end. The tubular body is made from a transparent material and has an inner diameter large enough to accommodate an endoscope.
US10433860B2
A transmission adapter for a medical instrument with a shaft, a transmission device movable in the shaft, and a manipulating device with a first part, which can be coupled mechanically rigidly to a proximal end of the shaft, and a second part, which is movable relative to the first part, includes a first coupling element for releasable mechanical coupling to the second part of the manipulating device, and a second coupling element for releasable mechanical coupling to a proximal end of the transmission device.
US10433852B2
The disclosure sets forth various exemplary embodiments of systems, methods, and/or medical apparatuses including but not limited to: a sheath; and a balloon disposed at a working distal end of the sheath. According to one example embodiment the medical device can include where the sheath can include woven wire reinforcing axial and longitudinal strength, side holes, a one direction distal valve, and can include an inflator. According to one example embodiment the medical device can include where the sheath can include a narrow cross-section of, e.g., 7-8 Fr and balloon of length of, e.g., 12 cm.
US10433851B2
In some embodiments, a medical device may include one or more of the following features: (a) a metal fabric formed of braided metal strands, (b) the medical device having a collapsed configuration for delivery through a channel in a patient's body and having a generally dumbbell-shaped expanded configuration with two expanded diameter portions, separated by a reduced diameter portion formed between opposed ends of the device and unsecured metal strand ends at the opposed ends, and (d) a thrombogenic agent located on the metal fabric.
US10433850B2
A ligature delivery device includes a control member, an elongated shaft, and an end effector attached to the distal end of the elongated shaft. An activation mechanism provides an user-operable connection between the control member and the end effector. In several embodiments, the end effector includes a reverse grasping mechanism. Several embodiments of ligature devices are adapted to be deployed endoscopically and/or translumenally using the reverse-grasping delivery device.
US10433847B2
There is described a platform device for use in forming an anastomosis and maintaining a desired curvature of a lumen in a desired shape during an anastomosis assistance period. The platform is formed from one or more bioabsorbable or biodegradable polymer filaments. There is also described a method for inserting a platform device for use in creation of an arteriovenous fistula by identifying a candidate artery and a candidate vein and dissecting the candidate vein. Next, inserting a platform device into the vein and creating a breach in the candidate artery at a desired angle and location. Next, introducing the platform device and vein into the candidate artery and forming the platform device into a curvature angle selected to minimize turbulent blood flow in an anastomosis formed by the vein and the artery. The platform may also be used to maintain potency of supply blood vessels and/or organ blood vessels or the lumens during an organ transplant procedure.
US10433845B2
A surgical staple cartridge is disclosed comprising a strip of staples removably stored within the surgical staple cartridge. The strip of staples comprises a plurality of staples, a base strip, and a plurality of connector portions joining the staples to the base strip.
US10433844B2
A surgical instrument including a surgical end effector and a threaded rotary input shaft. An actuator member is in operable engagement with the surgical end effector and is in selective threaded engagement with the threaded rotary input shaft such that when the actuator member is in an engaged configuration, rotation of said threaded rotary input shaft causes the actuator member to move axially to impart an actuation motion to the surgical end effector and when the actuator member is in a disengaged configuration, rotation of the threaded rotary input shaft will not be imparted to the actuator member. A switch may be employed for selectively moving the actuator between the engaged and disengaged configurations. A locking system may be employed for preventing axial movement of the actuator member when the actuator member is in the disengaged configuration.
US10433839B2
An apparatus includes a buttress body, an adhesive material, and a containment sheet. The buttress body is sized to fit on an anvil or a staple cartridge deck of a surgical stapler. The adhesive material is disposed on the buttress body. The adhesive material is configured to flow across the buttress body in response to a temperature exceeding a melting temperature. The containment sheet is disposed on the adhesive material. The containment sheet is secured relative to the buttress body such that the containment sheet is configured to contain the adhesive material on the buttress body.
US10433835B1
This is a laparoscopic instrument for facilitating intra-corporeal tying of knots. The shafts of two small diameter laparoscopic graspers are combined within a common external sheath. One grasper has a regular scissors handle, is stationary, and acts as a recipient grasper, while the other has no handle, but is rotatable and slidable, and acts as a donor grasper. It enables the head end of a suture to be actively passed from the jaws of the donor grasper to the jaws of the adjacent recipient grasper, after passing behind and around the tail strand, thus forming a knot. The current version of this instrument introduces two additional features, one being the passive production of the rotation by the straight sliding mechanism, the other being the use of free-wheeling levers allowing rotation of the shaft of the donor grasper, without rotating the attached levers in the slots.
US10433833B2
An apparatus includes first and second fixation members, a flexible member coupled to the first and second fixation members, and a limiting element coupled to the flexible member. The limiting element is movable relative to the second fixation member and acts to limit loosening of the flexible member relative to the second fixation member. The limiting element can be slidably received by the flexible member. The flexible member can be coupled to the fixation members such that pulling on a free end of the flexible member shortens a length of the flexible member between the fixation members.
US10433830B2
Methods and devices are provided for repairing a tear in a meniscus. A pair of fixation member each entailing a preformed knot configuration coupled together by a suture length. The fixation members are placed on the meniscal tissue with the suture length spanning the tear, the knot configurations are expanded to form anchoring knots and the suture length is shortened to close the tear.
US10433828B2
In a first aspect of the subject invention, an iris expander is provided which includes a non-metallic, unitary, multi-segmented body which is expandable from a first state to a second state. The second state defines a larger footprint than the first state with the body being defined by a plurality of segments connected by living hinges. In a further aspect, an iris expander is provided which includes a multi-segmented body that is expandable from a first state to a larger-footprint second state. At least one aperture is formed in the body with a channel extending therefrom embedded in the body such that no portion thereof is exposed externally of the body. The channel is formed to accommodate a portion of an instrument for causing adjustment of the body with avoidance of direct contact of the instrument with the tissue of the iris.
US10433827B2
A tissue puncture closure assembly including a wire assembly and first and second devices. The wire assembly includes a first wire member and a second wire member that each include a distal end portion and a proximal end portion. At least portions of the second wire member are arranged side-by-side with the first wire member. The distal end portion of the first wire member is connected to the distal end portion of the second wire member, and a proximal end portion of the first wire member is disconnected from the proximal end portion of the second wire member. The first device is operable to advance over the first wire member. The second device is operable to advance over the second wire member.
US10433825B2
Provided herein are systems for preparing and delivering fibrin sealant to a surface and methods of use thereof. In one embodiment, the system comprises: a. a quantity of a liquid mixture disposed within a container, the mixture comprising: I. fibrin or II. fibrinogen and Factor II; and b. a resin bed disposed within a vessel, the vessel capable of being in fluid communication with the container, wherein when in fluid communication, passage of the mixture through the vessel results in modification of the concentration of small molecules inhibitor(s) and/or inducer(s) within the mixture, favoring fibrin clot formation.
US10433819B2
Provided is an ultrasound diagnosis apparatus including: a data acquisition unit configured to acquire volume data for a head of an object; an image processor configured to detect a mid-sagittal plane (MSP) from the volume data, generate an MSP image corresponding to the MSP, detect at least one measurement plane based on the MSP, and generate at least one measurement plane image corresponding to the at least one measurement plane; and a display configured to display the MSP image and the at least one measurement plane image on a single screen.
US10433811B2
The present approach relates to self-calibration of CT detectors based on detected misalignment of the detector and X-ray source. The present approach make the detector more robust to changes against temperature and focal spot movements. The diagnostic image generated by energy resolving calibrated response signals is able to present enhanced features compared to conventional CT based diagnostic images.
US10433808B2
A set of rotary joint components containing stationary part(s) and rotatable part(s) repositionable with respect to each other. The stationary part has a stationary base with means for holding a stationary carrier into a circular-shaped form. The stationary carrier holds at least a stationary transmitter coupler of a contactless data link, such as a strip line. The stationary carrier is made of sheet metal or plastic material, and therefore can easily be prepared on a plane work bench before it is bent to a ring shape.
US10433803B2
An X-ray CT apparatus and an image reconstruction method are configured (i) to determine a movement phase to be used for generating diagnostic images with a small number of operations and (ii) to acquire diagnostic images in a short time while reducing a burden on an operator, such as when the target in scanning is a moving site. For example, an image processing device of an X-ray CT apparatus obtains movement information of a diagnostic site (such as the heart), determines phase selection positions, permits the operator to select an arbitrary movement phase based on the acquired movement information, and reconstructs selection images in a plurality of movement phases for each of the determined phase selection positions using scan data before presentation.
US10433802B2
A medical system (10) and method detects amyloid brain plaque. A positron emission tomography (PET) image of a brain is received. The PET image is generated from a radiotracer binding to amyloid brain plaque. A cortical profile is generated from the PET image. The cortical profile describes cortical tracer uptake to varying projection depths inside the cortex of the brain. The PET image is quantitatively assessed using the cortical profile and/or at least a portion of the cortical profile is displayed.
US10433798B2
An aperture comprises blocking members and for blocking X-rays. The blocking member has: an edge formed on an arc A1 lying on a circumference CF2 of a circle with radius r2 around a focal spot f in an XY-plane; an edge connected to one endpoint of the edge, the edge being formed to lie on the side of the X-ray detector with respect to an arc A11 contiguous to the arc A1; and an edge connected to the other endpoint of the edge, the edge being formed to lie on the side of the X-ray detector with respect to an arc A12 contiguous to the arc A1. The blocking member has: an edge formed on an arc A2 lying on the circumference CF2 of the circle with radius r2 around the focal spot f in the XY-plane; an edge connected to one endpoint of the edge, the edge being formed to lie on the side of the X-ray detector with respect to an arc A21 contiguous to the arc A2; and an edge connected to the other endpoint 23b of the edge, the edge being formed to lie on the side of the X-ray detector with respect to an arc A22 contiguous to the arc A2.
US10433797B2
According to at least one aspect, a method for computed tomography (CT) fluoroscopy can include acquiring a plurality of pairs of projections of an interventional device using CT fluoroscopy. Each pair of the projections can be obtained at a predetermined first angular separation greater than a second angular separation used for a full dose CT scan of a target object, by rotating a gantry of a CT scanner. The method can include identifying a position of the interventional device in real time for each pair of the projections, using back-projection of images of the interventional device from the respective pair of projections. The method can include superimposing an image of the interventional device on a 3-D image of an anatomical region at an identified position of the interventional device.
US10433796B2
System and related method to visualize image data. The system comprises an input port (IN) for receiving i) image data comprising a range of intensity values converted from signals acquired by an imaging apparatus in respect of an imaged object, and ii) a definition of a first transfer function configured to map a data interval within said range of said intensity values to an image interval of image values. A transition region identifier (TRI) identifies from among intensity values outside said data interval, one or more transition intensity values representative of a transition in composition and/or configuration of said object or of a transition in respect of a physical property in relation to said object. A transfer function generator (TFG) generates for said intensity values outside said data interval a second transfer function. The second transfer function is non-linear and has a respective gradient that is locally maximal around said transition intensity values. A renderer (RD) then renders, on a display unit (MT), a visualization of at least a part of said image data based on the two transfer functions.
US10433795B2
Disclosed are a radiation imaging system, an image processing device, a radiation imaging method, and a non-transitory computer-readable recording medium having an image processing program recorded thereon which facilitate the confirmation of a positional relationship between an object of interest and a biopsy needle. In the system using a radiation imaging device as a mammography device, when performing a biopsy of a breast of a subject, the positional relationship is confirmed using a radiation image (projection image) obtained through tomosynthesis imaging. A control unit reconstructs the projection image to generate a tomographic image in a state where the needle is inserted into the breast and generates a reprojection image at a predetermined angle from the tomographic image. The control unit extracts an image of the needle from the projection image, synthesizes the extracted image of the needle into the projection image while aligning, and displays the projection image.
US10433790B2
A catheter assembly or other elongate tubular device for use in establishing vascular or other access within the body of a patient is disclosed. The catheter assembly is equipped with one or more sensors that enable monitoring of one or more physiological aspects of the patient or physical aspect of the catheter assembly itself when the catheter assembly is disposed within the patient. Such aspects include central venous pressure, body temperature, ECG heart signals, oxygen levels, ultrasound data, glucose, etc. The catheter assembly includes the ability to wirelessly transmit or otherwise forward data relating to the detected physiological parameters to another location, such as a patient electronic medical record, smartphone or other mobile device, nurse station, etc. Catheter assemblies configured to detect the frequency of catheter flushing, flushing quality, etc., are also disclosed.
US10433782B2
A system for transmitting signals from a garment to an analysis device, is provided. The system includes a button attachable to the garment by means of a pin passing through a hole arranged in a garment coupling portion to be clamped between a head of said pin and a button coupling surface. The button coupling surface includes an electric contact connected to at least one integrated circuit contained in the button for performing analog and digital processing of signals coming from at least one garment sensor. The button contains a wireless module for communicating data between the button and an analysis device. The garment coupling portion is provided with at least one conductive trace arranged on its surface and which faces the button coupling surface. The electric contact is arranged in order to contact at least one conductive trace.
US10433780B2
Arrangements are provided including a base having a bore disposed therein extending from a first surface of the base through a second surface of the base, a fluid transport tube having a first end, a second end opposite the first end, and a lumen having an inner diameter, at least the second end of the tube being received within the bore of the base, and at least one fluid transport enhancing groove having at least a first section disposed in the second surface of the base and in fluid communication with the bore.
US10433775B2
A metabolite concentration is measured in vivo using Raman spectroscopy in such a way as to receive at a detector light scattered from the metabolite in interstitial fluid in skin in a measurement location at a depth of from 200-300 μm below the skin surface providing improved retention of correct calibration and transferability of calibration between individual subjects.
US10433772B2
A fingerprint sensor and a related terminal are provided. The fingerprint sensor includes a chip assembly and a protection element. The chip assembly includes a circuit board and a sealing element laminated on the circuit board. The protection assembly includes a first protection element. The circuit board is engaged with the first protection element to define a space to receive the sealing element, or the sealing element is engaged with the first protection element to define a space to receive the circuit board.
US10433760B2
The valve of an active breathing control (ABC) device can be driven by the output of the navigator channel of the MRI scanner, rather than by inference from a measured breath flow rate. Where the MRI scanner is integrated with a radiotherapy device, the MRI data can be used to trigger the enforced breath-hold by the ABC, and the radiotherapy delivered while the ABC valve is shut. If the MRI data pertains to the actual position of the tumor, then the ABC device will (in effect) hold the tumor at a precise and reproducible point for treatment.
US10433755B2
Method and system for determining a parameter which is indicative for whether a patient is delirious
Method for determining a parameter which is indicative for whether a patient is delirious or not, or is at risk of becoming delirious or not, wherein the method comprises the steps of: —providing electroencephalography (EEG) data comprising recording signals from at least two electrodes located on different locations on the patient's scalp during a predetermined time period, for instance at least 10 seconds, wherein at least one of the signals is recorded from the frontal half on the scalp; —processing said EEG data for obtaining a deviation signal from the two recording signals from the electrodes; —analyzing said deviation signal in the frequency spectrum for establishing slowing of said deviation signal and defining the parameter as the degree of slowing of said deviation signal which in combination with the locations of the recordings on the patient's scalp is indicative whether said patient is delirious or not, or is at risk of becoming delirious or not.
US10433751B2
A system and method for facilitating a cardiac rhythm disorder diagnosis based on subcutaneous cardiac monitoring data with the aid of a digital computer are provided. Cutaneous action potentials of a patient are recorded as electrocardiogram (EGC) data over a set time period using a subcutaneous insertable cardiac monitor. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks and the associated heart rates in the R-R interval plot.
US10433747B2
An apparatus for transmitting electrical signals is disclosed. The apparatus includes a substrate and a twisted pair of conductors located on the substrate. The twisted pair of conductors has a first layer comprising conductive material, a second layer comprising nonconductive material, and a third player comprising conductive material. The first layer has a plurality of segments separated by a plurality of gaps. The second layer is positioned in said gaps and electrically insulates a portion of the segments positioned within the gaps. The third layer is positioned over the second layer. The third layer is configured to electrically connects an end of one segment to an end of another segment. The twisted pair of conductors formed by the three dimensional structure comprises two electrically isolated conductors twisted about each other.
US10433745B1
An ECG system and a method for operating a handheld device that provides input to an ECG system are disclosed. The handheld device has a plurality of receiving channels. Each receiving channel includes an electrode that is adapted for receiving electrical signals from a patient's body when the electrode is pressed against the patient's body at a predetermined location on the patient's body. The method includes monitoring an output signal from each of the channels for any of a plurality of invalid signal conditions during a period of time in which the output signal is used to generate a standard lead or precordial lead trace, signaling a user that the handheld device is improperly positioned on the patient's body, and instructing the user on how to correct a placement of the handheld device based on the detected invalid signal condition.
US10433744B2
Methods and apparatuses, including devices and systems, for remote and detection and/or diagnosis of acute myocardial infarction (AMI). In particular, described herein are handheld devices having an electrode configuration capable of recording three orthogonal ECG lead signals in an orientation-specific manner, and transmitting these signals to a processor. The processor may be remote or local, and it may automatically or semi-automatically detect AMI, atrial fibrillation or other heart disorders based on the analyses of the deviation of the recorded 3 cardiac signals with respect to previously stored baseline recordings.
US10433739B2
In one embodiment, a data processing method comprises obtaining one or more first photoplethysmography (PPG) signals based on one or more first light sources that are configured to emit light having a first light wavelength corresponding to a green light wavelength; obtaining one or more second PPG signals based on one or more second light sources that are configured to emit light having a second light wavelength corresponding to a red light wavelength, one or more of the first light sources and one or more of the second light sources being co-located; generating an estimated heart rate value based on one or more of the first PPG signals and the second PPG signals; and causing the estimated heart rate value to be displayed via a user interface on a client device.
US10433738B2
The present embodiment relates to a method and apparatus for measuring a tissue variation signal (e.g. a photoplethysmographic (PPG) signal) without large direct current (DC) or low frequency (LF) offset which normally limit the sensor accuracy through motion artefacts and/or dynamic range requirements. The proposed solution is based on a separation of the PPG signal from the disturbance. This can be achieved by creation of a modulated PPG signal, or by creation of a differential PPG signal and an optimized sensor configuration which is adapted to remove DC or LF components.
US10433736B2
An implantable vessel fluid sensor is configured to sense at least one vessel fluid parameter of a vessel. The implantable vessel fluid sensor includes a tubular body having a first end portion. The first end portion is configured to be inserted into and to form a sealed junction with an open vessel end of the vessel. The implantable vessel fluid sensor further includes a sensor unit connected to the tubular body. The sensor unit includes a sensor region configured to be in direct contact with the vessel fluid in a sealed junction state. A minimum distance between the sensor region and the first end portion is at most 10 times an outer diameter of the first end portion of the tubular body.
US10433713B2
An anti-leak valve unit is removably attached to a base end portion of an overtube through which an endoscope is removably insertable. The anti-leak valve unit includes a frame portion attachable to the overtube, a fitting device on the frame portion that is removably engageable with the base end portion, and a valve element provided inside the frame portion. The frame portion and the fitting device can be embodied as first through third interconnected covers and first and second members attached to the first cover at edges thereof. The valve element can be embodied as a flexible member with an annular endoscope insertion port in a flexible elastic portion thereof.
US10433706B2
A portable system for imparting a reciprocating motion between a driving member and a driven member. The driving member has an upper and lower surfaces joined by one or more edges and includes a battery-powered drive mechanism. The driven member includes a treatment surface. First and second spaced apart studs extend from one of the members, and first and second spaced apart slots are formed in the other member. A locating recess is formed in each of the slots into which the studs are received. The drive mechanism is connected to one of the studs to impart a linear reciprocating motion thereto when the driven member is attached to the driving member. The connection between the driving member and the driven member is effected by each stud being entered into the respective slot and then moved into the respective locating recess by a twist-fit action.
US10433688B2
A cleaner includes: a suction unit; a suction motor that generates suction force for sucking air through the suction unit and includes an impeller; a dust separation unit that includes one or more cyclone units generating cyclonic flow to separate dust from air flowing inside through the suction unit; a dust container that stores dust separated by the dust separation unit and is disposed under the suction motor; a battery disposed behind the dust container to supply power to the suction motor; and a handle disposed behind the suction motor, wherein a rotational axis of the impeller and an axis of the cyclonic flow vertically extend and an extension line from the rotational axis of the impeller passes through the one or more cyclone units.
US10433684B1
A seat cushion paper device (230) includes an receiving box (233), multiple pieces of folded seat cushion paper (231), and multiple mounting members (232). Each piece of seat cushion paper (231) includes a first end (2311), a second end (2312), and a fixing portion (2314). The first ends (2311) of the pieces of seat cushion paper (231) are sequentially accommodated at a bottom end (2332) of the receiving box (233), the fixing portion (2314) of the pieces of seat cushion paper (231) are sequentially fixed to a top end (2331) of the receiving box (233), and each of the second ends (2312) of the pieces of seat cushion paper (231) is provided with a mounting portion (332). In addition, also provided is a toilet. The toilet comprises a toilet body (100) and a toilet cover (200). The toilet cover (200) is movably mounted on the toilet body (100). The toilet cover (200) comprises a cover plate (210), a seat cushion ring (220), the seat cushion paper device (230), and the accommodating room (240). The accommodating room (240) is mounted on the cover plate (210). The seat cushion paper device (230) is accommodated in the accommodating room (240). By means of the design of the receiving box (233) and the fixing portions (2314) of the seat cushion paper (231), the pieces of the seat cushion paper (231) do not topple over due to the gravity effect of the pieces of the seat cushion paper (231) when the toilet cover plate (210) is erected, and accordingly all the pieces of the seat cushion paper (231) in the seat cushion paper device (230) are prevented from being mixed together, thereby allowing the toilet to be conveniently used.
US10433683B2
A disposable toilet seat cover/sanitizer includes a base layer and a barrier layer adjacent thereto, the disposable toilet seat cover/sanitizer having at least at least one portion thereof treated with a detergent and/or a disinfectant, the at least one treated portion is generally centrally arranged and is surrounded by a non-treated portion, the treated and non-treated portions are delimited by a perforation, the treated portion being detachable from the disposable toilet seat cover/sanitizer, thereby creating a central opening in the untreated portion. A method is also provided for preparing a toilet seat cover/sanitizer, the method includes: providing a substrate or base layer; treating, at least partially, the substrate with a detergent and/or a disinfectant; applying a barrier layer to a side of the base layer opposite to the side that was treated with the detergent and/or disinfectant; providing perforations around the treated portion, thereby defining a boundary between the seat cover portion the sanitizing portion; and packaging the cover/sanitizer.
US10433680B2
A sealing assembly for a bathing enclosure includes a receptacle having a lower flange, a side flange projecting from the lower flange, and an upper flange projecting from an upper end of the side flange. The assembly further includes a base, defining an outwardly-extending flange at an upper end thereof, the outwardly-extending flange configured to interface with the lower flange of the receptacle. The assembly further includes a seal configured to be received in the receptacle, the seal having a compliant member having opposing first and second sides, a first member having an inner surface configured to engage the first side of the compliant member, and a second member having an inner surface configured to engage the second side of the compliant member. An upper surface of the compliant member is configured to be compressed by the upper flange of the receptacle.
US10433676B2
The cutting board with a drainage valve allows for the collection and drainage of liquids associated with cutting, slicing and chopping of foodstuffs. The cutting board has first and second longitudinally opposed ends, first and second laterally opposed sides, an upper surface and a lower surface. A liquid collection reservoir is defined in the upper surface adjacent the first longitudinally opposed end of the cutting board. At least one peripheral channel is defined in the upper surface of the cutting board and is in open communication with the liquid collection reservoir. A drainage port is formed through the lower surface of the cutting board adjacent the first longitudinally opposed end. The drainage valve is mounted in the cutting board for selectively controlling drainage of liquid from the liquid collection reservoir to the drainage port.
US10433675B2
A food processor includes a base, a motor disposed within the base, a drive shaft operatively connected to the motor and extending outwardly from the base, the output shaft being rotatable upon actuation of the motor, a bowl removably coupled to the base, a lid removably coupled to the bowl so as to define a processing chamber, a slicing assembly positioned within the processing chamber and driven by the motor, the slicing assembly being positionable in a plurality of slicing positions to produce sliced food items of varying thicknesses, and a slice thickness adjustment mechanism operable to move the slicing assembly between the plurality of slicing positions. The slice thickness adjustment mechanism includes a cartridge mounted to the bowl, the cartridge including an actuator drivingly coupled to a drive screw. Rotation of the drive screw causes the slicing assembly to move between the plurality of slicing positions.
US10433672B2
An infant bottle feeding system includes an infant bottle with a chamber that receives a liquid, heating or cooling elements operable to heat or cool liquid in the chamber and sensors operable to sense parameters of the liquid in the chamber. The system optionally includes an electronic base removably attached to a bottom surface of the infant bottle and operable to deliver power to electronics in the infant bottle. The system optionally includes a thermal cover that fits over the infant bottle and releasably couples to the electronic base to enclose the infant bottle, the thermal cover insulating the infant bottle and inhibiting heat loss of the liquid in the chamber. The electronic base delivers power to the heating elements and sensors in the infant bottle only when the infant bottle is on the electronic base. The infant bottle, thermal cover and electronic base define a single travel pack unit when coupled together.
US10433665B2
A valve assembly for a leak resistance drinking cup is selectively configurable between a sealed position and an unsealed position. The valve assembly includes a plug having an inner surface, an outer surface, and an opening extending through the plug from the outer surface to the inner surface. An amount of vacuum acting on the outer surface of the plug needed to move the valve assembly from the sealed position to the unsealed position is less than the amount of internal pressure acting on the inner surface of the plug needed to move the valve assembly from the sealed position to the unsealed position.
US10433662B2
Systems and kits for assembling and/or modifying a blanket-based structure are disclosed. An exemplary system includes an enclosure element having one or more attachment mechanisms fixedly attached to the enclosure element and configured to detachably associate with one or more environmental structures. The exemplary system additionally includes a plurality of connection features, a plurality of complementary connection, and a plurality of eyelets disposed along the perimeter of the enclosure element. The exemplary system additionally includes one or more weights selectively attachable to the enclosure element at one or more of: the attachment mechanisms, the plurality of connection features, the plurality of complementary connection features, the plurality of eyelets, or combinations thereof.
US10433661B2
A picture frame device includes a main frame unit and a first pressing unit. The main frame unit includes a frame body having a front plate, two connecting plates extending integrally and backward from two opposite sides of the front plate respectively, and two extending plates extending integrally and respectively from the connecting plates and toward each other. The front plate, the connecting plates and the extending plates cooperatively define an accommodating space. The frame body is made of a transparent plastic material. The first pressing unit includes a plurality of first fastening portions respectively disposed on the extending plates, and a plurality of first pressing portions respectively disposed on the first fastening portions in a way that each first pressing portion is moveably engaged with one of the first fastening portions and moveable toward or away from the front plate.
US10433659B1
An interactive retail display unit includes a movable case having a plurality of shelves, an upper rail assembly including a rail having a first end and an opposing second end and at least one bearing slidably coupling the movable case to the rail and a lower track and roller assembly. The lower track and roller assembly includes a track having a first end corresponding with the first end of the rail, an opposing second end corresponding with the second end of the rail and a plurality of wheels mounted to a bottom of the movable case. The movable case is configured to move along the rail and the track.
US10433650B2
Linear dual actuator for lying or sitting furniture having at least two sections (2,3), which with one end is rotatably embedded in the article of furniture and where each section (2,3) with an arm (5,7) secured to a pivot shaft (4,6) can be adjusted by means of the linear dual actuator. The dual actuator comprises a housing (8) with a drive at each end, which comprises an electric motor (11), which through a transmission (12) is in driving connection with a spindle (13). On the spindle (13) is arranged an activation element (14) with a spindle nut in engagement with the spindle (13), where the activation element (14) can be brought into engagement with the arm (5,7) for adjusting the sections (2,3). In case of power failure there is the problem that the back rest and leg rest section cannot be lowered to a plane level, which can make the bed uncomfortable or completely impossible to sleep in. This problem is solved in that a rotating element in the drives comprises a connection (21), which is accessible from the outer side of the housing (8) for connecting a tool, e.g. an Allen key (22) for driving the respective drives for the back rest and leg rest section (2,3) for lowering of these to a horizontal position.
US10433645B2
Seating device (1) comprising a base plate (2) for a user to sit on and a pelvic support (3) for supporting in a vertical position the pelvis of a user sitting on said base plate (2) without supporting or immobilising said user's vertebrae, wherein said pelvic support (3) is configured for contacting said pelvis (9) at the posterior superior iliac spines (PSIS) (91) and/or at the iliac crests (92), without any contact to said user's vertebrae wherein said seating device is configured for maintaining an angle of 93° to 97° between the vertically supported pelvis (9) and the femoral bones of said user. In embodiments, the seating device includes a mechanism to encourage the user's upper body mobility, for example a convex base.
US10433639B2
An assembly includes a threaded male connector, a threaded female connector, and an adapter configured to be threadably connected to each of the threaded male connector and the threaded female connector. The adapter is configured such that at least one of the threaded male connector and the threaded female connector can be disconnected from the adapter by rotating a portion of the adapter relative to the threaded male connector and the threaded female connector while holding the threaded male connector and the threaded female connector positionally fixed relative to one another.
US10433637B1
A work surface that attaches to a portable transportation and storage device is provided. The work surface has a tray and legs. The tray has a planar top surface defined by a rear edge, a front edge, and side edges. A lip extends upward from the top surface along each edge. Attachment points on the tray mount the tray to the portable transportation and storage device. The legs have a leg clamping device that mounts the legs to the portable transportation and storage device. The legs include a height adjustable portion configured to selectively extend the length of the legs, and a pivot portion that is rotatable relative to the height adjustable portion.
US10433633B1
A convertible carrying case having a first container and a second container that is convertible between a primary configuration and a secondary configuration. Each container having a primary face (with primary access structure for accessing the interior of the container when the convertible carrying case is in the primary configuration) and a secondary face (with secondary access structure for accessing the interior of the container when the convertible carrying case is in the secondary configuration). A first matable half and a second matable half of an openable-closeable connection are connectable to secure the containers in either a primary configuration or a secondary configuration. Preferably, contents within the containers may remain during conversion between the primary configuration and the secondary configuration. A method for converting a convertible carrying case between the primary configuration and the secondary configuration.
US10433625B1
A fitted cap case that has a cap cover assembly having a front cover and a rear cover, a cap base assembly having a front base and a rear base, and a bottom base assembly having a front bottom base and a rear bottom base. The front cover closes onto the front base. The rear base and the rear bottom base slide within a cavity defined between the front base and the front bottom base to elongate or reduce a predetermined distance between a cap mount protrusion and a notched edge. The front cover closes onto the front base, and the rear cover closes, whereby rear cover lateral edges are partially positioned onto first and second channels, and lateral edges relatively align with a base edge.
US10433620B2
A waterproof fastener chain includes: a pair of fastener tapes made of polyester resin adjacent to each other at a given space between each side edge thereof, rows of elements respectively attached onto a main surface of the side edge of each of the fastener tapes, and waterproof coated films made of polyester resin respectively formed on a main surface of each of the fastener tapes. An outer surface of each of the waterproof coated films is flat at least at a position where a slider is to pass over, each of the waterproof coated films penetrates into irregularities on the main surface of each of the fastener tapes, a penetration depth of the waterproof coated films into a gap caused by the space of the pair of fastener tapes is not more than thickness of the fastener tapes.
US10433616B2
A sole structure for shoes includes a midsole and a plate member made of a hard resin harder than the midsole, which is joined to a lower surface of the midsole. The plate member includes a first reinforcement portion extending rearwardly from a position corresponding to a portion in the rear of a thenar of a user along a medial side arch region and a second reinforcement portion extending rearwardly on a lateral side from the position corresponding to the portion in the rear of the thenar of the user so as to avoid a position corresponding to a portion more frontward than a center of a fifth metatarsal bone.
US10433594B2
A vented coveralls is disclosed. Said vented coveralls comprising a bottom portion and a top portion. Said bottom portion having two legs and a top portion having two sleeves. Said top portion having a front, a back, a first side, a second side and one or more vents. Said vents are capable of allowing an air flow to pass through said vented coveralls. Said bottom portion comprises a trouser portion and said top portion comprises a shirt portion of said vented coveralls.
US10433592B2
Provided are half corsets and methods of using them. The half corsets provide improved comfort and a quicker way of fastening and unfastening them. The half corsets have a body garment with four sides, two lateral garments, a flap that connects two of the sides with each other via a couple of fastener patches, and at least two support strips. The half corsets are designed to be worn around an individual's abdomen, pelvic region, and upper thighs.
US10433582B2
An electrically operated aerosol generating device is provided, including an electrical power supply; an electronic circuit board; an electrical heating element configured to receive power from the electrical power supply via the electronic circuit board; and a ground plane comprising an elongate conductive member configured to electrically couple the power supply to the electronic circuit board and the electrical heating element, and to structurally retain the power supply and plurality of components of the electrically operated aerosol generation device. There is also provided a ground plane, and a single laminar blank configured to form the ground plane. A method of assembling an electrically operated aerosol generating device is also provided.
US10433581B2
A cartridge for an electronic vaping device may include at least one inner tube along a length of the cartridge. The inner tube defines a passageway. A heating element is within the inner tube and has a longitudinal axis. A jacket at least partially surrounds the heating element. The tube segment is positioned between the heating element and the inner tube along the longitudinal axis of the heating element.
US10433569B2
The disclosure extends to methods, systems, and devices for producing a shaved ice or snow cone products and providing toppings thereto. The system may comprise an ice shaving or snow cone machine, a mobile edifice, and a topping dispenser attached to the mobile edifice.
US10433566B1
A method for inspecting peeled shrimp by human operators in a culling station illuminated by ambient visible light and in a dark shell-detection booth illuminated by ultraviolet (UV) lamps. The UV radiation emitted by the lamps is filtered to remove visible light from the filtered UV irradiating the shrimp in the dark booth. Irradiated shrimp shell fluoresces and is detectable by the naked eye. A human operator in the dark booth detects the fluorescing shell and removes those shrimps.
US10433564B2
The invention relates to a method for anaesthetizing animals before slaughter, by the anesthetic action of gases or gas mixtures, operated in “batch” mode, in which the live animals, preferably put together in one or more cages, are placed in a lock chamber for treatment where the animals are brought into contact with anesthetic gas, following a cycle comprising several steps characterized by different contents of anesthetic gas, characterized in that at least one of the steps is carried out using gas recovered from the lock chamber and stored in at least one capacity (2, No. 1, No. 2 etc.) for temporary storage having a variable volume.
US10433559B2
A food processing attachment for a food processing device includes a rotational adapter configured to be selectively coupled with a drive system of the food processing device. A food holder is coupled to the rotational adapter and having a base, wherein the food holder is selectively rotated by the rotational adapter. A central spear extends perpendicularly from a center of the base. A plurality of radial flanges extend perpendicularly from the base, wherein each radial flange of the plurality of flanges is discontinuous with the other radial flanges, wherein the central spear and the plurality of radial flanges are adapted to secure a food item in a processing space and in communication with the rotational adapter. A blade is coupled to an operable carriage and is adapted to selectively engage the food item within the processing space to remove at least a portion of the food item.
US10433558B2
An oven appliance includes a cooking chamber disposed within a housing with an opening in the housing for accessing the chamber. A casing is disposed around the opening. An air flow restriction door for limiting air flow within the cooking chamber is provided.
US10433555B2
This disclosure relates to picolinamides of Formula I and their use as fungicides.
US10433552B2
This invention relates to processes for the preparation of antiparasitic isoxazoline compounds enriched in an enantiomer using quinine-based chiral phase transfer catalyst. The invention also relates to novel quinine-based phase transfer catalysts and to a toluene solvent form of the isoxazoline compound of the invention.
US10433549B2
A non-nematicidal composition comprises at least one glucan and/or at least one fucan which act individually or synergistically with mannitol to reduce losses in crop yield and marketable grade caused by the infestation of growth media with plant pathogenic nematodes, to levels equivalent to those achieved with commercial nematicides, but without posing a risk to the ecosystem or user. In some cases the composition comprises at least one glucan, at least one fucan and at least one mannitol which may be in a weight/weight ratio of approximately 1:2:3 of at least one glucan:at least one fucan:at least one mannitol or between approximately 1:1:1 to 1:1:3 of at least one glucan:at least one fucan:at least one mannitol.
US10433547B2
The present invention relates generally to peroxyformic acid forming compositions, methods for forming peroxyformic acid, preferably in situ, using the peroxyformic acid forming compositions. The present invention also relates to the peroxyformic acid formed by the above compositions and methods. The present invention further relates to the uses of the peroxyformic acid, preferably in situ, for treating a surface or a target. The present invention further relates to methods for treating a biofilm using peroxyformic acid, including peroxyformic acid generated in situ.
