US11053363B2
A random mat material including fiber bundles, said fiber bundles including fibers having an average fiber length of 5 to 100 mm, and having an average number N of fibers in the fiber bundle that satisfies: 1.5 × 10 5 D 2 < N < 4.5 × 10 5 D 2 wherein D is the average diameter of fibers in the fiber bundle, expressed in micrometers, and the standard deviation SDN of the number of fibers in a fiber bundle satisfies: 1,000
US11053361B2
A concentrate carrier system for adding colorants and/or other additives to resin formulations over a broad range of processing temperatures is described. The carrier system includes at least 20 wt. % of a base acrylate copolymer, such as ethyl-methyl acrylate, provided in combination with less than 30 wt. % of polycarpolactone, or a similar ring-opened cyclic ester or ether derivatives. The remainder, which may include an optional organic plasticizer such as epoxidized soybean oil, is dedicated to an additive package that may include colorants, property enhancers, and/or non-property fillers.
US11053357B2
The present invention provides a spherical powder having properties, such as an excellent strength, toughness, and deformation recovery, and provides a method for producing same. The present invention provides: a spherical powder containing a crosslinked body formed having (A) a polyrotaxane in which both ends of a pseudopolyrotaxane, which are formed by inclusion of the opening of a cyclic molecule by threading therethrough with a linear molecule, are provided with a capping group so that dethreading of the linear molecule is prevented, in particular, a spherical powder having an average particle diameter of 0.5 to 1,000 μm, preferably 1 to 500 μm, more preferably 1 to 300 μm, and still more preferably 1 to 150 μm; and a method for producing this spherical powder.
US11053347B2
A curing agent for epoxy resins, containing at least one amine adduct of formula (I) which can be obtained as an addition product of a mixture of a primary diamine, a monoalkylated other diamine and a polyepoxide. The curing agent makes it possible to produce low-odor, low-emission epoxy resin products, in particular coatings, which have a surprisingly low viscosity, a high curing rate, a high final hardness, and a surprisingly appealing surface.
US11053344B2
A hybrid composition includes an isocyanate, a polyester having at least one carbon-carbon double bond and at least one hydroxyl group, castor oil present in an amount of from 5 to 30 weight percent, a catalyst, and a solvent. The hybrid composition can be formed using various methods. The method may include combining the isocyanate and the castor oil to form a first adduct, combining the polyester, the solvent, and the catalyst to form a second adduct, and combining the first adduct and the second adduct. The method may alternatively include combining the castor oil, the solvent, and the polyester to form a third adduct, combining the third adduct with the isocyanate, and combining the catalyst with the third adduct and the isocyanate. The method may alternatively include combining the catalyst and the isocyanate component to form a fourth adduct, and combining the third and fourth adducts.
US11053341B2
A rigid polyurethane foam comprises the reaction product of an isocyanate and a thixotropic composition. The thixotropic composition comprises: a first polyether polyoi which is aromatic amine initiated and has ethylene and propylene oxide end capping; a second polyether polyoi having a viscosity at 25° C. of from about 500 to about 15,000 cps; a third polyether polyoi having a viscosity at 25° C. of from about 18,000 to about 60,000 cps and a functionality of from about 5 to about 7; and a hydrofluoroolefin. The thixotropic composition has a viscosity at 25° C. of from about 350 to about 5,000 cps. A method of forming a composite article comprising a substrate and the rigid polyurethane foam includes the steps of providing the thixotropic composition, providing an isocyanate, combining the thixotropic composition and the isocyanate to form a reaction mixture, and applying the reaction mixture to the substrate to form the composite article.
US11053337B2
The disclosure relates to a thermoset omniphobic composition, which includes a thermoset polymer with first, second, and third backbone segments, first urethane groups linking the first and third backbone segments, and second urethane groups linking the first and second backbone segments. The first, second, and third backbone segments generally correspond to urethane reaction products of polyisocyanate(s), hydroxy-functional hydrophobic polymer(s), and polyol(s), respectively. The thermoset omniphobic composition has favorable omniphobic properties, for example as characterized by water and/or oil contact and/or sliding angles. The thermoset omniphobic composition can be used as a coating on any of a variety of substrates to provide omniphobic properties to a surface of the substrate. Such omniphobic coatings can be scratch-resistant, ink/paint resistant, dirt-repellent, and optically clear. The thermoset omniphobic composition can be applied by different coating methods including cast, spin, roll, spray and dip coating methods.
US11053335B2
Novel methods and materials particularly useful for ophthalmic applications and to methods for making and using the same are disclosed herein. More particularly, relatively soft, optically transparent, foldable, high refractive index materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and implanting IOLs made therefrom are disclosed.
US11053332B2
Embodiments of the invention described herein relate to a polyethylene polymer composition suitable for use in the manufacture of packaging articles, flexible films and/or sheets. In one embodiment, the copolymer comprises a polyethylene resin with density 0.918 g/cm3 to about 0.935 g/cm3, G′ at G″(500 Pa) value, as determined from Dynamic Mechanical Analysis at 190° C., of less than 40 Pa, Mz/Mw of greater than 2, CDBI50 of greater than 60. Other embodiments relate to polymer compositions with defined molecular characteristics and formulations suitable for use in the manufacture of articles including films, sheets, bags and pouches with improved creep resistance and high toughness and a good balance of film stiffness and processability in monolayer and/or multi-layer film structures.
US11053331B2
The present invention relates to a cascade process useful for (fast) ionic polymerisation of liquid monomer(s) containing reaction mixture for the production of the corresponding polymer(s).
US11053324B2
Objects of the present invention are to provide a phosphoric acid-esterified fine cellulose fiber of which slurry shows superior transparency, and to provide a method for producing a phosphorylated fine cellulose fiber showing superior transparency with good efficiency and high yield. According to the present invention, there is provided a phosphoric acid-esterified fine cellulose fiber, of which 0.2 mass % aqueous dispersion shows a solution haze of 15% or lower.
US11053318B2
The present invention provides a bispecific construct comprising a first binding domain specifically binding to CD33 and a second binding domain specifically binding to CD3 for use in a method for the treatment of myeloid leukemia, wherein the construct is administered for a maximal period of 14 days followed by a period of at least 14 days without administration of the construct. Moreover, the invention provides a method for the treatment of myeloid leukemia comprising the administration of a therapeutically efficient amount of such bispecific construct and the use of such bispecific construct for the preparation of a pharmaceutical composition for the treatment of myeloid leukemia.
US11053316B2
The present invention is directed to optimized anti-CD3 variable sequences for use in a variety of bispecific formats, including those that utilize scFv components. The invention further relates to nucleic acids encoding for the polypeptide, to vectors comprising the same and to host cells comprising the vector. In another aspect, the invention provides for a pharmaceutical composition comprising the mentioned polypeptide and medical uses of the polypeptide.
US11053314B2
Described herein is the discovery that cancer stem cells (CSCs) can be induced to differentiate by altering CD47 signaling. Provided herein are methods and compositions for inducing differentiation of cancer stem cells, for instance irreversible differentiation, including methods of treating subjects with cancer such as breast cancer, colon cancer, lung cancer, ovarian cancer, or melanoma, and including metastatic as well as primary cancer. Also provided are methods for treating subjects with triple negative breast cancers involving forcing differentiation of bCSCs of the subjects through targeting of CD47.
US11053313B2
An object of the present invention is to provide a novel molecule which has high specificity to CLDN-5 and recognizes an extracellular domain of CLDN-5. The object is achieved by an antibody which specifically recognizes a three-dimensional structure or a primary structure of an extracellular domain of a Claudin-5 protein.
US11053311B2
The present disclosure provides a human antibody or antigen binding fragment thereof or an antibody construct comprising a human binding domain or antigen binding fragment thereof capable of binding to human CDH19 on the surface of a target cell. The disclosure relates to a nucleic acid sequence encoding the antibody or antigen binding fragment thereof contained in the antibody construct, a vector comprising the nucleic acid sequence and a host cell transformed or transfected with the vector. Furthermore, the disclosure relates to a process for the production of the antibody construct of the disclosure, a medical use or a method of treatment using the antibody construct and a kit comprising the antibody or antigen binding fragment thereof or the antibody construct.
US11053309B2
The present invention provides methods for treating, preventing or reducing the severity of active eosinophilic esophagitis. In certain embodiments, the present invention provides methods of increasing esophageal distensibility. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4/interleukin-13 (IL-4/IL-13) pathway inhibitor such as an anti-IL-4R antibody.
US11053307B2
This disclosure provides compositions and methods for controlling pain. In particular the disclosure provides a method for controlling pain comprising co-administration of an NGF antagonist and a TNFα antagonist. The NGF antagonist and the TNFα antagonist can be separate molecules or part of a multifunctional polypeptide, e.g., a multispecific binding molecule that comprises an NGF antagonist domain and a TNFα antagonist domain. This disclosure also provides multifunctional polypeptides, e.g., multispecific binding molecules, comprising an NGF antagonist domain, and a TNFα antagonist domain. The method provides improved pain control. Administration of an NGF antagonist and a TNFα antagonist as provided herein can control pain in the subject more effectively than an equivalent amount of the NGF antagonist or the TNFα antagonist administered alone.
US11053302B2
The present invention relates to single domain antibodies comprising at least one modification relative to the 4D5 antibody scaffold or human germline VH3 domain, the modifications selected from the group consisting of H35D, A78V, S93V, S93G and W103R, with the position numbering being according to the Kabat numbering scheme. Disulfide-free variants further comprise at least one additional modification selected from the group consisting of C22S, A24I, A24L and C92T, and with the proviso that at least one of C22S and C92T is present. Further encompassed are the multi-modular antibody molecules and antibody conjugates comprising single domain antibodies, as well as methods for producing them. The invention in particular provides a library of the single domain antibodies or multi-modular antibody molecules and a method for selecting an antibody that binds an antigen.
US11053297B2
Disclosed herein are methods of increasing numbers of monocytes to a tumor or cancer metastasis site in a subject. Non-limiting embodiments include administering or using a Nur77 polypeptide or subsequence thereof; a Nur77 agonist; a CX3CR1 agonist; CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+ GR1− (Ly6C−)) monocytes; CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+GR1− (Ly6C−)) monocytes contacted with a Nur77 agonist or contacted with a CX3CR1 agonist. Also disclosed herein are methods of increasing, stimulating, activating or promoting monocyte migration to or mobilization against a tumor or cancer metastasis in a subject. Non-limiting embodiments include administering a Nur77 polypeptide or subsequence thereof; a Nur77 agonist; a CX3CR1 agonist; CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+GR1− (Ly6C−)) monocytes; or CD14+ CD16+ monocytes and/or CD14dimCD16+ (CD115+CD11b+GR1− (Ly6C−)) monocytes contacted with a Nur77 agonist or contacted with a CX3CR1 agonist.
US11053293B2
The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to an NKG2D ligand or PD1 ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. The present disclosure also encompasses compositions and methods for recruiting cytotoxic lymphocytes to target cells using NKG2D receptor ligands or PD1 ligands. The compositions disclosed herein comprise a NKG2D receptor ligand and a targeting molecule and may improve immunotherapy by limiting side effects associated with immunotherapy.
US11053281B2
Disclosed herein are peptoids and related compounds, including peptoid affinity ligands for binding and/or purifying immunoglobulins, immunoglobulin fragments or immunoglobulin fusion proteins thereof. Methods of making peptoid affinity ligands and using the same to bind, purify and/or isolate immunoglobulins and related compounds are also disclosed. Such peptoid affinity ligands comprise a peptoid compound consisting of sequentially coupled peptoid residues forming a peptoid backbone, with one or more functional groups appended to a nitrogen of the peptoid residues of the peptoid backbone configured to provide the desired binding affinity.
US11053280B2
The present disclosure pertains to compositions comprising aflibercept and methods for producing such compositions in chemically defined media and using chromatography to reduce amounts of certain aflibercept variants.
US11053279B2
The present invention relates to a method for site-selective coupling of a first agent to a second agent, comprising the steps of: contacting a first agent comprising at least one furan moiety with an activation signal and with a second agent comprising at least one hydrazine moiety or at least one hydroxylamine moiety, thereby activating said furan moiety to an activated furan moiety; and reacting said activated furan moiety with the hydrazine moiety or the hydroxylamine moiety, thereby site-selectively coupling said first agent to said second agent.
US11053274B2
The present invention relates to a process for the preparation of a compound of formula (I) said process comprising the steps of: a) reacting a compound of formula (II), with an acylating or a silylating agent to produce a compound of formula (III), wherein P1 and P2 are each independently a protecting group selected from R2—Si—R3R4, or R1CO—, wherein R1 is a group selected from C1-6alkyl or C3-6cycloalkyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; R2, R3 and R4 are each independently a group selected from C1-6alkyl or phenyl, each group being optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; b) reacting the compound of formula (III) in the presence of palladium acetate or a derivative thereof to produce compound of formula (IV); and c) reacting the compound of formula (IV) with a reducing agent to produce compound of formula (I).
US11053269B2
Unsymmetrical metallocene compounds based on cyclopentadienyl ligands are disclosed, as well as catalytic compositions comprising the compounds supported on solid support materials. The compounds and compositions are useful as catalysts in the polymerisation of olefins. In particular, the compounds and compositions are useful catalysts in the preparation of low molecular weight polyethylene (e.g. polyethylene wax) and copolymers formed from the polymerisation of ethylene and other α-olefins.
US11053265B2
An optically active 2,3-bisphosphinopyrazine derivative represented by the following general formula (1): wherein R1 represents a group selected from a branched alkyl group having 3 or more carbon atoms, an adamantyl group, an optionally substituted cycloalkyl group, and an optionally substituted aryl group; R2 represents a group selected from a branched alkyl group having 3 or more carbon atoms, an adamantyl group, and an optionally substituted cycloalkyl group, provided that when R1 is a tert-butyl group, R1 and R2 are not the same; R3 represents a monovalent substituent; n represents an integer of 0 to 4; and * represents an asymmetric center on a phosphorus atom.
US11053263B2
A trichlorogermanide of formula (I): [R4N]/[R4P]Cl[GeCl3] (I), where R is Me, Et, iPr, nBu, or Ph, tris(trichlorosilyl)germanide of formula (II): [R4N]/[RrP][Ge(SiCl3)3] (II), where R is Me, Et, iPr, nBu, or Ph, a tris(trichlorosilyl)germanide adduct of GaCl3 of formula (III): [Ph4P][Ge(SiCl3)3*GaCl3], and a tris(trichlorosilyl)germanide adduct of BBr3 of formula (IV): [Ph4P][Ge(SiCl3)3*BBr3]. Also, methods for preparing the trichlorogermanides of formula (I), the tris(trichlorosilyl)germanide of formula (II), the tris(trichlorosilyl)germanide adduct of BBr3 of formula (IV).
US11053258B2
The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds to treat disorders associated with GSK-3.
US11053255B2
Disclosed herein are methods of synthesizing mahanine and related compounds. The synthesis features an intramolecular aryl-alkyne isomerization, transition metal catalyzed cross-coupling and intramolecular carbazole forming reaction.
US11053252B2
Fused cyclic pyrimidine compounds, including tautomers thereof, and pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, are disclosed having the general Formula I: These compounds are useful in methods for treating cancer, selectively targeting cancerous cells via the proton coupled folate transporter, folate receptor alpha, and/or folate receptor beta pathways, inhibiting GARFTase in cancerous cells, and selectively targeting activated macrophages in a patient having an autoimmune disease, such as rheumatoid arthritis.
US11053244B1
Disclosed are compounds of Formula (I) N-oxides, or salts thereof, wherein G, A, R1, R5, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
US11053240B2
Described herein are 2-amino-quinoline derivatives that are agonists of toll-like receptors 7 and 8 (TLR7/8), pharmaceutical compositions, and methods of use of the compounds and compositions to treat various diseases, such as viral, cancer, and allergic diseases, in need thereof by administering a therapeutically effective amount of a 2-amino-quinoline derivative.
US11053236B2
Compounds, compositions, and methods for the treatment of infections, inflammation, cancers, tinnitus, Meniere's disease, hearing loss, or bipolar disorder, or for providing cytoprotection against Clostridium difficile toxins, are disclosed.
US11053217B2
The present invention provides: a methyl 1-{2-[(3S,4R)-1-[(3R,4R)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)pyrrolidine-3-carbonyl]-4-(methoxymethyl)pyrrolidin-3-yl]-5-(trifluoromethyl)phenyl}piperidine-4-carboxylate 1/2 ethane-1,2-disulfonic acid which is represented by formula (1) and is excellent in crystallinity; and a method for producing the same; and a production intermediate thereof; and a production method using this compound.
US11053214B2
The present invention provides new pseudo-polymorphs of the hemisuccinate salt of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide which are useful in pharmaceutical compositions, for example, for the treatment and prevention of migraine headache.
US11053212B2
Compounds of formula (I) and salts thereof: wherein R1, R2, R3, R4 are defined herein. Compounds of formula (I) and salts thereof have been found to inhibit the binding of the BET family of bromodomain proteins to, for example, acetylated lysine residues and thus may have use in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis; and cancers.
US11053200B2
A method for producing a radiofluorinated compound having an aromatic or heteroaromatic ring carrying [18F] fluorine as first substituent, a bonding unit, which can bind to a peptide or peptide mimetic, and a spacer group connected via bond A1 to the bonding unit and via bond A2 to the ring, wherein the bonding unit has second substituent(s) —OH, —CONH, and/or —COOH. The steps include (a) providing a precursor having the ring carrying a substituent Y, bonding unit with the second substituent(s), and spacer group, wherein substituent Y is —N+(R1R2R3), —NO2, —Cl, —Br, —F, or —I, and R1, R2, and R3 are independently C1-C6 alkyl; and (b) reacting the precursor with a [18F] fluoride anion in the presence of an activation salt to the radiofluorinated compound, which has a cation N+(R4R5R6R7) with R4, R5, R6, and R7 being independently C1-C6 alkyl, wherein the substituent Y is replaced by [18F] fluoride.
US11053186B2
A process for the production of glycolic acid or a derivative thereof comprises: reacting formaldehyde with carbon monoxide and water in a carbonylation reactor in the presence of a sulfur catalyst, said reactor operating under suitable conditions, such that glycolic acid is formed; recovering a first product stream comprising glycolic acid, impurities and a sulfur species in the carbonylation reactor; passing the first product stream to an esterification reactor where it is subjected to esterification to form an alkylglycolate and wherein the esterification is catalysed by the sulfur species recovered in the first product stream; recovering a second product stream comprising the alkylglycolate, sulfur species and impurities from the esterification reactor; separating the sulfur species from the second product stream and recycling it to the carbonylation reactor in step (a) to form a sulphur depleted second product stream; separating the alkylglycolate from the sulphur depleted second product stream in a distillation zone; and recovering the alkylglycolate and converting the alkylglycolate to glycolic acid.
US11053180B2
The method according to this disclosure is a method for separating an unsaturated hydrocarbon having 2 or 3 carbon atoms and a halogenated unsaturated carbon compound formed by replacing at least one of hydrogen atoms included in the unsaturated hydrocarbon with a fluorine atom, from each other and is a method for selectively adsorbing either the unsaturated hydrocarbon or the halogenated unsaturated carbon compound by a porous coordination polymer that includes a metallic ion having a valence of 2 to 4 and an aromatic anion having 1 to 6 aromatic ring(s).
US11053178B2
A multi-stage dehydrogenation process including contacting, in a first stage, a feed stream comprising a hydrocarbon and steam with a dehydrogenation catalyst under dehydrogenation conditions to yield a first stage effluent, heating the first stage effluent, and contacting, in a second stage, the heated first stage effluent with a dehydrogenation catalyst under dehydrogenation conditions to yield a second stage effluent comprising a dehydrogenation product, wherein the first stage includes a first reactor and a second reactor arranged in parallel, and wherein the second stage includes a third reactor connected in series with the first reactor and the second reactor. A multi-stage dehydrogenation system for carrying out dehydrogenation is also provided.
US11053174B2
The present application relates to systems and methods for processing organic material. The methods may include extraction of biochemical nutrients from organic material, such as food scraps. The method can include comminuting the organic material to form a slurry from components comprising liquid and organic material; combining the slurry with microorganisms, such as a yeast, under aerobic conditions to form a mixture of the slurry and yeast; aerating the mixture; and forming a biomass and a nutrient-rich broth, in which the biochemical nutrients are stabilized and anabolized. The systems may, in some embodiments, be configured to perform the methods of processing organic materials.
US11053171B2
Biochars and methods for treating biochars are provided that are useful in various applications, including, but not limited to, applications related to the raising, care, maintenance, disease prevention, disease treatment and odor control of animals.
US11053164B2
A solar control glass article includes a transparent substrate provided with a thin multilayer coating having solar control properties. The thin multilayer coating includes an absorber layer sandwiched between a first and second transparent dielectric layers, a functional layer protected by an upper and lower blocker layers and a third transparent dielectric layer provided over the upper blocker layer. The thickness of the functional layer and the thickness of the transparent dielectric layers are adjusted to give a gold colored reflection on a surface opposite to the first surface of the transparent substrate provided with a thin multilayer coating.
US11053162B2
A method of reworking lithium containing ion exchanged glass articles is provided. The method includes a reverse ion exchange process that returns the glass article to approximately the composition of the glass from which the glass article was produced, before being subjected to ion exchange. The reworked glass articles exhibit a K2O concentration profile comprising a portion wherein a K2O concentration increases to a local K2O concentration maximum.
US11053154B2
An additive manufacturing process includes forming an object material stack using sheet materials without use of binder material between the sheet materials and forming features of the cross-sectional layers of a 3D object in the corresponding sheet materials. Another process involves forming features of the cross-sectional layers of a 3D object in soot layers of a laminated soot sheet. A manufactured article includes three or more glass layers laminated together without any binder material between the glass layers. At least one of the glass layers is composed of silica or doped silica, and at least one feature is formed in at least one of the glass layers.
US11053148B2
A device and method for shortcut nitrogen removal and nitrite-oxidizing bacteria activity inhibition are disclosed herein. An embodiment of the present invention provides a yarn fiber diffuser comprising: a plurality of yarn fibers on which bacteria can be attached and grow; and an inlet capable of supplying gas to one sides of the plurality of yarn fibers, wherein the gas includes oxygen and carbon dioxide, nitrite can be produced by the oxygen, and the concentration of oxygen in the gas is adjusted by the oxygen and the carbon dioxide.
US11053142B2
The exemplary embodiments provides a desalination device comprising an electrochemical cell comprising a porous positive electrode, a porous negative electrode, and a membrane positioned between the porous positive electrode and the porous negative electrode, the electrodes comprising a network of conductive material comprising a plurality of electrode active materials dispersed throughout the conductive material, the porous negative electrode and the porous positive electrode have the same electrode active material, a power supply to supply a current to the electrochemical cell, an inlet for providing a feed stream to the electrochemical cell, a first outlet line for removing a concentrated effluent and a second outlet line for removing a desalinated effluent. Also provided is a desalination device having a plurality of electrochemical channels with alternating anion and cation selective membranes, and a porous negative and positive electrode having the same electrode active material.
US11053140B2
A water disinfection system preferably includes a battery compartment, a control printed circuit board (PCB) to manage several parameters including timing, voltage rate, and user-interface. A high voltage power supply is coupled to a set of electrodes to cause an electric discharge. The electric discharge results in a series of reactions in the water that eliminate bacteria and viruses, dissolves organic material, and oxidizes inorganic compounds.
US11053134B2
Synthesizing lithium lanthanum zirconate includes combining a reagent composition with a salt composition to yield a molten salt reaction medium, wherein the reagent composition comprises a lithium component, a lanthanum component, and zirconium component having a lithium:lanthanum:zirconium molar ratio of about 7:3:2; heating the molten salt reaction medium to yield a reaction product; and washing the reaction product to yield a crystalline powder comprising lithium lanthanum zirconate.
US11053131B2
The invention relates to a process for the preparation of alkali metal cyanides as a solid substance, comprising the steps of: i) an absorption step in the form of an absorption of hydrogen cyanide from a hydrogen cyanide-containing synthesis gas in an aqueous alkali metal hydroxide solution; ii) a crystallization step in the form of introducing said alkali metal cyanide solution into an evaporative crystallizer; iii) a separation step; iv) a recycle step; v) a drying step.
US11053124B2
Disclosed herein is a conductive grease composition that includes a functionalized carbon nanomaterial and/or boron nanomaterial and a base oil. The nanomaterial and base oil forms hydrogen bond network in the disclosed composition. Because of the formed hydrogen bonds, the disclosed grease exhibits enhanced thermal or electrical conductivity. Also disclosed is a method to improve thermal or electrical conductivity of an existing grease composition.
US11053122B2
A continuous combustion production equipment for synthesizing ton-grade fullerenes and a synthetic process therefor. The continuous combustion production equipment is equipped with a gas supply and flow control system, a liquid supply and flow control system, a vaporization and preheating system, a combustion furnace, a combustor, a spray nozzle, an ignition system, a filter tank, a product collection system, a vacuum control system, a vacuum measuring and displaying unit and a circulation water cooling system. Opening the supply line of gas fuels, arranging the tip of a metal electrode of the ignition system near the gas fuel outlet of the combustor, opening the ignition system, igniting the gas with an electric spark to generate a flame; initiating the vacuum pump set; opening the supply line of liquid raw materials, adjusting to a suitable flux with a constant flow pump; adjusting the pressure of the system to keep it below 5000 Pa.
US11053116B2
The present invention discloses a Micro-Electro-Mechanical System (MEMS) acoustic pressure sensor device and a method for making same. The MEMS device includes: a substrate; a fixed electrode provided on the substrate; and a multilayer structure, which includes multiple metal layers and multiple metal plugs, wherein the multiple metal layers are connected by the multiple metal plugs. A cavity is formed between the multilayer structure and the fixed electrode. Each metal layer in the multilayer structure includes multiple metal sections. The multiple metal sections of one metal layer and those of at least another metal layer are staggered to form a substantially blanket surface as viewed from a moving direction of an acoustic wave.
US11053115B2
A transducer modulus, comprising: a substrate; a cap on the substrate, defining a chamber; and a sensor modulus in the chamber, integrating a first MEMS transducer facing the chamber, and a second MEMS transducer facing the supporting substrate. The cap has a first opening that forms a path for access of the first environmental quantity exclusively towards a sensitive element of the first transducer, and the supporting substrate has a second opening that forms a path for access of the second environmental quantity exclusively towards a sensitive element of the second transducer.
US11053104B2
A boom for a pipelaying machine includes a pair of posts located in a first plane and disposed in a tapered configuration with respect to a second plane transverse to the first plane. The boom also includes a cross-brace disposed between the pair of posts and located partway along a length of the pair of posts. The cross-brace includes a first link member and a second link member disposed along the first plane. Further, each of the first and second link members are angularly offset from each other and the second plane respectively. Furthermore, ends of the first and second link members are rigidly attached to the pair of posts. The cross-brace further includes a first rib member and a second rib member disposed along the second plane and rigidly attached to the first link member and the second link member respectively.
US11053093B2
Disclosed is a wind-up system and a method for winding-up a strip. The wind-up system includes a first work station and a first supply member for supplying the strip to said first work station. The first work station includes a first collection area for holding a first collection reel to collect and wind-up the strip; a first liner area for holding a first liner reel to unwind a liner, and a first guide area extending from the first liner area into the first collection area, wherein the unwound liner is unwound from the first liner reel through the first guide area onto the first collection reel. The wind-up system further includes a pick-and-place member for picking-up a leading end from the first supply member and for placing the picked-up leading end of the strip onto the liner within the first guide area.
US11053089B2
A printing apparatus includes a conveyance unit configured to convey a tray on which a printing medium is placed, a printing unit configured to perform printing on a print surface of a printing medium on the tray based on a print job, and a first detection unit configured to detect a relative position relationship between the tray and a printing medium placed on the tray. In addition, a control unit is configured to control the printing unit not to perform printing in a case where the first detection unit detects that the printing medium is not placed at an appropriate position, and a selecting unit is configured to select whether to continue printing irrespective of results of the detection by the first detection unit.
US11053087B2
The present invention related to a method and a device for removing food products from a belt conveyor, comprising a belt conveyor comprising two ends, an endless belt and a drive, for transporting food products on the endless belt from a feed location towards a discharge location, wherein the endless belt comprises a transporting side and a returning side; a removing device for removing food products from the endless belt, comprising: a roller, facing the returning side of the endless belt, wherein the roller is arranged at a predetermined distance from the endless belt; and a frame part, for holding the roller at the predetermined distance; wherein the endless belt is configured to rotate in a first direction and wherein the roller is configured to rotate in the same direction as the endless belt.
US11053076B1
Technology for optimizing carton induction in an order fulfillment picking system is described. In an example embodiment, a method, implemented using one or more computing devices, may include receiving scan data reflecting status of cartons being conveyed by a conveying system, receiving confirmatory input reflecting pick completion for a subset of the cartons being conveyed by the conveying system, and generating an estimated time of arrival for one or more cartons not yet inducted into the conveying system based on the scan data and the confirmatory input. The method may further include generating a load forecast based on the estimated time of arrival and inducting one or more of the one or more cartons into the conveying system based on the load forecast.
US11053073B2
A storage system is described where goods are stored in containers and the containers are stored in stacks. Above the stacks runs a grid network of tracks on which load handling devices run. The load handling devices take containers from the stacks and deposit then at alternative locations in the stacks or deposit then at stations where goods may be picked out. The framework may be provided with one or more of the following services: power, power control, heating, lighting, cooling, sensing, and data logging. A method of partitioning the storage system prevents the spread of fire or prevent damage caused by sprinkler activation.
US11053071B2
A trash container lid locking apparatus comprises a pivot device including a mounting plate configured to be secured to a side edge of a trash container close to a front of the container, a pivot arm having a first end pivotally coupled to the mounting plate and a second end, the second end having an attachment portion to couple to an elongated bar which is longer than the front of the trash container, the pivot arm including a hole therein, and a housing including a rotating lock mechanism having a movable element that is operable by the rotating lock mechanism into and out of the hole of the pivot arm to lock and unlock the pivot arm and bar with respect to the hinged container lid of the trash container.
US11053069B2
The invention relates to a capsule (10) designed for food or beverage preparation, the capsule (10) comprising a cup-shaped base body (1), a top wall (2) and a bottom retaining wall (3) for holding food or beverage preparation ingredients, wherein the base body (1) is made of one single injection-molded piece and wherein a side wall (4) of the base body comprises at least one co-injected multilayer section (5) having two outer layers (5a) being made from a different polymeric material than a core layer (5b), and wherein the base body (1) further comprises a bottom structure (6) which is integrally molded with the side wall (4) and comprising opening means (7) allowing the capsule to be opened at the time of its use.
US11053066B2
A syringe propellable by propellant that boils at a predetermined temperature, the syringe including a barrel having an outlet at a front end, and a stopper axially moveable in the barrel. The stopper separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe further includes a third chamber for containing propellant. Upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapor pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament through the outlet. At least one trigger for triggering an action is provided, the trigger activated in response to the pressure in the second chamber satisfying a predetermined condition.
US11053065B2
A dispensing assembly, including a case including at least one aperture, a drive gear operatively arranged to engage the case, a tablet disc rotatably arranged in the case and including a plurality of compartments, and an electronics assembly, including a motor engaged with the drive gear, and a housing operatively arranged to engage the tablet disc, wherein the motor is arranged to rotate the electronics assembly and the tablet disc with respect to the case to align the plurality of compartments with the at least one aperture.
US11053063B2
The invention comprises a dispensing device having an elongated body, a sidewall which is elliptical in at least a portion of its cross-section, an open top end, and a dispensing bottom end. The device comprises a ratchet, ratchet support member, dial, telescoping members, and an elliptical plunger. The ratchet support member and dial each engage the ratchet to allow movement in certain directions and prevent movement in other directions, beyond a certain point. A first telescoping member having the smallest diameter is affixed to the ratchet. The interior diameter of a second telescoping member is larger than the exterior diameter of the first telescoping member, such that the first telescoping member is configured to nest within the interior of the second telescoping member. The first telescoping member may be extended a distance through the dispenser body via rotation of the ratchet. The plunger is affixed to the telescoping member having the largest diameter.
US11053060B2
A substantially moisture tight container and lid assembly for storing and packaging moisture-sensitive items comprising an assembly with a container and a lid, the lid is attached by a hinge to an upper housing portion of the container, the lid includes a lip seal member that depends downwardly from the lid, the lip seal member is configured to abut at least a portion of the interior side of the container when the lid is in the closed position resulting in a substantially moisture tight seal between the lid and the lid, and the container assembly further comprising a base portion and an upper housing portion, the upper housing portion is capable of being snap-fit into the base portion by employing a lip seal mechanism to form a substantially moisture-tight seal.
US11053059B2
The present application discloses a vacuum sealed container, including a container body, a container lid, a vacuum generator, at least one magnifier and an indicator. The container body includes a first wall and a bottom surface, wherein the first wall and the bottom surface define an accommodation space. The container lid is coupleable to the container body. The vacuum generator is coupled to the container lid to evacuate fluid from the accommodation space. The at least one magnifier is coupled to the container body. The indicator is coupled to the container. A method for using the aforementioned vacuum sealed container is also disclosed.
US11053049B1
A size adjustable box is disclosed herein. The size adjustable box includes a plurality of box sections slidably adjustable relative to one another, the plurality of box sections configured to collectively define a box interior and an upper box rim; and a plurality of lid sections slidably adjustable relative to one another, the plurality of lid sections configured to be received on the upper box rim so as to generally enclose the box interior. The slidable adjustability of the plurality of box sections and the plurality of lid sections allows a user to adjust an overall size of the box.
US11053043B2
The present invention relates to a method and an arrangement for emptying a flexible container (30) of bag contents (31) therein. Such a flexible container includes a bottom opening (34) in its lower end and a top opening (37) in its upper end. When this container is to be emptied of its contents, it is placed in an emptying arrangement in such a way that the container's bottom opening lies below the top opening. The flexible container is then turned around an axis of rotation that unites said bottom opening and top opening. The turning motion produced is gradually propagated from the container's upper end towards its lower end whereby the container is twisted into a tight string (32). This twisting contributes to removing the bag contents (31) from the flexible container via the bottom opening (34) provided or made therein.
US11053041B2
An automatic packing device (1) for cushioning element (s) (2) in a carton (C) is mounted along a conveyor (4) directed along a longitudinal axis (Y, Y′). The packing device (1) includes a robotic cell (3) associated with a cushioning element storage zone (2), the robotic cell (3) including at least one gripping device fo a cushioning element (2). The storage zone includes at least one magazine (18) with at least one cassette (8) movable along a transverse axis (X, X′) from a loading position to an unloading position.
US11053036B2
A process and apparatus can be used to vacuum skin package a product arranged on a support comprising providing a film portion above said support with the product being arranged between the support and the film portion; air tightly fixing the film portion to the support; removing at least a portion of air from a volume underneath said film portion through said at one nozzle inserted in an interspace between the film portion and the support.
US11053032B1
A lidding station for containers, including a conveyor structured and arranged for moving unrestrained containers in a conveyance direction; a lid infeed chute above said conveyor; and first, second and third compression rollers positioned above said conveyor and downstream of said lid infeed chute, and methods for affixing lids to containers.
US11053029B1
A modular spacecraft is provided. The modular spacecraft includes a bus module and a payload module. The bus module provides additional thermal radiative capacity for the payload module by including a bus-panel payload thermal zone that couples operational components of the payload module to a radiator panel in the bus module. The bus module also includes its own operational components that are thermally coupled to the radiator panel but that are thermally isolated from the payload module and the bus-panel payload thermal zone.
US11053021B2
An unmanned aerial vehicle (UAV) has: a body for carrying an article; at least one rotor; and a light source for generating a light beam to indicate the landing zone for the UAV. The UAV, in use, is flown to a desired location, that might be a site of an emergency with no defined landing zone. The UAV descends, and, while descending the light source is operated to illuminate and to define a landing zone. The UAV can be provided with lights and an audio source to warn and advise bystanders that the UAV is landing and to stand clear of the landing zone.
US11053018B2
An inlet for a flight vehicle engine, such as for a supersonic or hypersonic engine, includes an internal flow diverter to divert boundary layer flow. The flow diverter is configured to minimize disruption to flow outside the diverted boundary by being configured through use of a flow field that is also used to configure the walls of the inlet. The flow field that is used to configure an inlet-creating shape and a diverter-creating shape has the same flow generator, contraction ratio, compression ratio, mass capture ratio, pressure ratio between entrance and exit, and/or Mach number, for example. The internal diverter may be configured so as to allow arbitrary selection of a leading edge shape for the internal diverter, for example to use a shape that helps avoid radar detection.
US11053011B2
Ice detection systems for aircraft and related methods are disclosed. A disclosed example ice detection system includes a thermochromic device to sense a temperature of freestream air relative to a temperature threshold, and a hydrochromic device to sense an amount of moisture in the freestream air relative to a moisture threshold. A controller to detect an icing condition in response to the thermochromic device sensing a temperature that is less than or equal to the temperature threshold and the hydrochromic device sensing an amount moisture that exceeds the moisture threshold.
US11052994B2
A turbine engine module including an upstream propulsive unit including a propellers doublet that are upstream and downstream, respectively mounted around an axis, a power turbine shaft with axis of rotation intended for rotating the propellers doublet, a speed reducer connected to the propellers doublet and driven by the shaft, and, a pitch-changing system including a cylinder that controls the pitch of the blades of the upstream propeller the rotational axis of the propellers doublet is shifted in relation to that of the shaft. The cylinder is placed downstream of the reducer, and the pitch-changing system includes a shaft for controlling the pitch of the blades that connect the cylinder to the blades of the upstream propeller.
US11052986B2
An aeronautical glazing unit includes at least one sheet of modified acrylic, wherein the sheet is combined with at least one other sheet of modified acrylic, and/or at least one sheet of cast poly(methyl methacrylate) (PMMA), and/or at least one sheet of another transparent polymer such as polycarbonate (PC), and/or at least one sheet of glass in particular that is chemically strengthened, as a laminated and/or multiple glazing unit.
US11052980B2
An underarm float for infants, comprising a main body, the main body is composed of a front part and rear parts, which are connected to each other, wherein rear parts are connected to both ends of the front part, and rear parts at the two ends of front part are oppositely arranged; a first arc groove and second arc grooves are formed at the joint between front part and a rear part, first arc groove is downwards recessed along the upper surface of the front part and the rear part, and the second arc grooves are inwards recessed along the side surface of the front part and the rear part; a shoulder strap is arranged at the joint between the front part and the rear part, and the shoulder strap is located above the first arc groove; and the oppositely arranged rear parts are provided with an elastic cord.
US11052977B2
A tubular installation apparatus (1) including a lay tower (2) mounted to a support structure (4). The lay tower (2) is configured to lower a tubular section along a firing line (L) extending along the lay tower (2). A magazine (3) is removably mounted to the lay tower (2) and configured to be pre-loaded with a plurality of tubular sections. A feed mechanism (23, 25) is configured to feed one or more tubular sections from the magazine (3) to the firing line (L) of the lay tower (2) for connection to the end of a catenary.
US11052968B2
An electric bicycle comprises a removable battery pack (1) for storing electrical energy, and a frame element (5) to which the battery pack (1) is intended to be fixed. The battery pack comprises a housing and a lock arranged in said housing and the frame element (5) comprises a projecting locking element (21), said locking element (21) penetrating into the housing of the battery pack (1) through an entry opening so as to co-operate with said lock with a view to fixing said battery pack (1) to said frame element (5).
US11052963B2
A throttle tube assembly including a throttle tube, a throttle body, a bearing, and a stop collar. The throttle tube extends along a central axis from a proximal most end to a distal most end, the throttle including a lumen extending through the throttle tube. The throttle body is connected to the throttle tube, at the proximal end of the throttle tube, the throttle body having a bearing seat aligned along the central axis with the throttle body. The bearing being disposed in the bearing seat and axially aligned with the throttle body and partially axially aligned with the throttle tube. The stop collar is fixed to the throttle body configured and arranged to actuate a throttle by wire system.
US11052955B2
A spare wheel catcher in a vehicle comprises a base adapted to be connected on a rear differential and a catcher plate. The base includes a support extending along a longitudinal direction of the vehicle at an assembled position and a connection member; and the catcher plate is connected with a first end of the support and forms an obtuse angle with a forward moving direction of the vehicle.
US11052949B2
Provided is a rear vehicle body structure that includes: a right and left pair of frame members each extending in a front-rear direction and having a damper supporting part; rear wheel wells; a rear floor panel; a rear cross member upper part connecting the right and left pair of frame members to each other on a front side of the damper supporting parts; front side reinforcements provided along a vehicle cabin inner side of each of the rear wheel wells and extending in an up-down direction on the front side of the damper supporting parts; and a reinforcing member mounted on each of the frame members and having a reinforcing member main body that reinforces the damper supporting part and a reinforcing member coupling part that couples together the rear cross member upper part and the front side reinforcement.
US11052935B2
A motor-adjustable steering column for a vehicle includes a supporting unit attachable to a vehicle body and by which there is held an adjusting unit in which a steering spindle is mounted so as to be rotatable about a longitudinal axis. An adjustment drive is connected to the supporting unit and to the adjusting unit and is adjustable relative to the supporting unit. The adjustment drive includes a drive unit and a threaded spindle which engages in a spindle nut and which has a threaded spindle axis. The threaded spindle and the spindle nut can be driven to rotate relative to one another about the threaded spindle axis by the drive unit. To prevent slipping or spinning of the spindle drive in a crash situation the adjustment drive includes a blocking device which can be brought into a blocking position for blocking the threaded spindle relative to the spindle nut.
US11052922B2
An information processing apparatus is provided with a controller comprising at least one processor. The controller is configured to execute: displaying presentation information to be presented to a user of a vehicle at an inside or an outside of a window formed in a vehicle; switching over between displaying and non-displaying of the presentation information displayed at the inside of the window according to an instruction received from the user; and displaying the presentation information at the outside of the window in cases where the vehicle is located in a specific place.
US11052915B2
A sobriety ignition interlock system including an engine control device and a method for managing available vehicle engine power using the sobriety ignition interlock system. The engine control device includes an engine control processor (ECP) that is electronically connected in between an engine control unit (ECU), an engine sensor assembly, and a sobriety processor. The sobriety processor determines a sobriety level of a vehicle driver and sends a corresponding sobriety signal to the ECP. The ECP intercepts an engine signal transmitted from the engine sensor assembly to the ECU and manipulates the engine signal according to the sobriety signal, in order to manage the available power of the vehicle engine.
US11052911B2
The speed control device is equipped with: an actual speed acquisition unit; an actual position acquisition unit; an acceleration/deceleration control unit; and a travel resistance calculation unit. When in a situation in which an target speed increases from a first target speed to a second target speed, the target speed in the second road section is set such that an actual speed increases with a first-order lag from the first target speed to the second target speed over a period between the start position and end position of the second road section, and the target speed in the second road section is set such that the amount of change in the speed, which increases with the first-order lag, with respect to the travel time of the vehicle is decreased as the travel resistance calculated by the travel resistance calculation unit increases.
US11052898B2
Systems and methods for operating a vehicle that includes an engine that may be automatically stopped and started are described. In one example, a requested driver demand power may be filtered via a first order low pass filter in response to a powertrain speed. The filtered requested driver demand power may be a basis for automatically stopping and starting an engine.
US11052892B2
An electronically controllable pneumatic brake system. The brake system includes at least two brake circuits, wherein a first of the at least two brake circuits is allocated an electrically and pneumatically controllable control valve and a second of the at least two brake circuits is allocated an electrically controllable parking brake valve in order to predetermine braking pressures so as to actuate wheel brakes of the respective brake circuit. The brake system further includes a first control unit configured to electrically actuate the electrically and pneumatically controllable control valve in dependence upon a vehicle desired deceleration and a second control unit configured to electrically control the parking brake valve in dependence upon the vehicle desired deceleration that is requested in an automated manner. In addition, the brake system includes at least one bypass valve to which a control valve is allocated.
US11052887B2
An electric component assembly includes a housing with which an electric component is fitted, and the electric component and the housing are fixed to one surface of a base body. The electric component includes a connection terminal press-fitted to a through-hole (201a) of a board provided in the housing, and an insertion direction of the connection terminal into the through-hole is a fitting direction of the electric component with the housing. The electric component assembly includes a rib which is protrudingly provided on either one of an outer surface of the electric component intersecting the fitting direction and an inner surface of the housing facing the outer surface, and a groove portion which is provided as a recess on another one of the surfaces and the rib is inserted into; and a protrusion that abuts onto the rib is provided on an inner surface of the groove portion.
US11052885B2
A system and a method for estimating the coefficient of friction of a hydraulic brake system with axle-individual pressure buildup of a motor vehicle. In addition, a system and to a method for setting the target braking torque of a hydraulic braking system with axle-individual buildup of a motor vehicle in order to obtain a desired actual braking torque.
US11052883B2
Driving support ECU transmits a communication connection request to a help net center HNC when a driver of a vehicle has been determined to be in an abnormal state where the driver loses an ability to drive the vehicle, and when the communication connection to the help net center HNC has been established, the driving support ECU transmits the help signal (the positional information of the vehicle) and decelerates the vehicle at a constant deceleration to make the vehicle stop. On the other hand, when the communication connection to the help net center HNC has not been established, the driving support ECU makes the vehicle travel at a constant speed. Accordingly, it is possible to make the vehicle stop under a situation where the help net center HNC recognizes the vehicle position inside which the driver who has been determined to be in the abnormal state is.
US11052870B2
A switch assembly for a vehicle seat belt buckle comprising a switch housing defining an interior and a pocket, a cable extending into the interior and including hook-shaped ends extending around posts in the interior of the switch housing. In one embodiment, the interior of the switch housing includes first and second posts positioned in a co-linear and spaced apart relationship and the hook-shaped ends face each other and extend around the first posts and abut against the second posts. In one embodiment, the Hall Effect sensor is positioned in the pocket of the switch housing in an inclined relationship.
US11052869B2
A seatbelt ignition interlock system. The system includes a plurality of sensor devices each including a housing, a latch configured to removably engage the latch receiver of a vehicle seatbelt system, a latch receiver configured to receive and removably engage the latch of the vehicle seatbelt system, a latch sensor, a temperature sensor, and a power source. Each sensor device is in electrical communication with a vehicle ignition interlock circuit, and the vehicle ignition interlock circuit is in electrical communication with an ignition of a vehicle. The vehicle ignition interlock circuit is configured to prevent the vehicle ignition from being started when a combination of temperature sensors and latch sensors determine that occupied seats have unfastened seatbelts.
US11052862B2
Provided is an air bag base cloth constituted by a composite material obtained by coating fabric made of synthetic fibers with a synthetic resin. The average value of the 100% modulus in the warp direction of the fabric texture included in the composite material and the 100% modulus in the weft direction of the fabric texture included in the composite material is 50 N/cm or less. The 100% elongation recovery rate is 95% or more. The 100% elongation load air permeability is 0.1 L/cm2·min or less both before and after thermal treatment at 100° C.
US11052857B2
An assembly includes a belt and one of a buckle or a clip. The belt has a first inflatable portion inflatable to an inflated position, a second inflatable portion inflatable to an inflated position, and an intermediate portion between the first inflatable portion and the second inflatable portion. The intermediate portion includes a fluid channel connecting the first inflatable portion to the second inflatable portion. One of the buckle or the clip is slidably attached to the intermediate portion.
US11052851B1
Developing intelligent systems which take into consideration the economical, environmental, and safety factors of the modern society, is one of the main challenges of this century. Progress in the fields of mobile robots, control architectures, artificial intelligence, advanced technologies, and computer vision allows us to now envisage a smart environment future.
The rise of the connected objects known as the “Internet of Things” (IoT) will rival past technological marvels. This application discloses a time synchronous communication IoT network and IoT ranging device to monitor a smart environment. IoT ranging device uses a time of day (TOD), an absolute time, and a time slot assigned to it by IoT network for ranging in the smart environment in order to avoid interference and collision.
US11052849B2
A vehicle member comprises a wooden member and a resin cover member integrally covering the wooden member. The vehicle member absorbs or transmits a received load. The cover member integrally includes a load acting portion and an attaching portion. The wooden member is positioned in the vehicle member so that a shaft center direction of annual rings is aligned with an input direction of the load. The attaching portion is attachable to an attached member of a vehicle.
US11052839B2
A binding structure of wire routing materials are formed by: elongated wire routing materials; a binding member for binding the wire routing materials; and an engaging member including a movable body portion including an engaging portion for assembly into a vehicle body, and a bound portion to be bound and held together with the wire routing materials by the binding member. The bound portion includes a main portion facing the wire routing materials, and a leg portion extending from the main portion and being in contact with the wire routing materials. The movable body portion includes a sliding portion disposed such that sliding thereof is allowed on the wire routing materials in a gap.
US11052834B2
A method for providing image processing for a plurality of vehicular driving assist systems includes mounting a camera module at a portion of an in-cabin side of a windshield of a vehicle. The camera module houses a camera, a circuit board, at least one electrical connector and an image processor. The camera is electrically connected to circuitry of the circuit board via a flexible electrical connection. With the camera module mounted at the vehicle windshield, electrical power is provided to the camera via the flexible electrical connection, the camera is controlled via the circuitry, the camera is operated to capture image data, which is provided to the circuitry via the flexible electrical connection and is received at the circuitry. The image processor processes the image data received at the circuitry of the circuit board for the plurality of driving assist systems of the vehicle.
US11052829B2
An accessory arm for a lift truck includes at least one rear attachment mechanism affixed to a rear overhead guard leg of the lift truck and a front attachment mechanism affixed to a front overhead guard leg of the lift truck. The accessory arm further includes an accessory bar rotationally mounted to the at least one rear attachment mechanism and to engage with the front attachment mechanism when the accessory bar is in a closed position. A wiring harness connected to a battery of the lift truck and routed within the accessory bar to a device mounted to the accessory bar, the wiring harness to provide power to the device.
US11052828B2
A rack for a truck includes a rail system having a first rail and a second rail each having a first end and a second end. The second rail is configured to be spaced apart from and positioned parallel to the first rail. A first support structure and a second support structure each have a first end and a second end and a cross member having a first end and a second end configured to laterally extend between said first rail and said second rail. The first support structure and the second support structure are configured to engage with said rail system. At least the first support structure is configured to be slidably positioned within the rail system such that the first support structure abuts the second support structure in a closed or unloaded configuration and is separated from the second support structure in an open or loaded configuration.
US11052823B2
A vehicle rear monitoring system includes a camera that captures an image of an area to a rear of a vehicle, and a processing unit that processes the image captured by the camera. The processing unit creates a first vehicle rear image that is displayed in a first display area that is a portion of a display area of a display device, when traveling forward, and creates a second vehicle rear image that is displayed in a second display area that is within the display area of the display device and that is an area that includes the first display area and is larger than the first display area, when traveling backward.
US11052821B2
Specifically programmed, integrated motor vehicle dangerous driving warning and control system and methods comprising at least one specialized communication computer machine including electronic artificial intelligence expert system decision making capability further comprising one or more motor vehicle electronic sensors for monitoring the motor vehicle and for monitoring activities of the driver and/or passengers including activities related to the use of cellular telephones and/or other wireless communication devices and further comprising electronic communications transceiver assemblies for communications with external sensor networks for monitoring dangerous driving situations, weather conditions, roadway conditions, pedestrian congestion and motor vehicle traffic congestion conditions to derive warning and/or control signals for warning the driver of dangerous driving situations and/or for controlling the motor vehicle driver use of a cellular telephone and/or other wireless communication devices.
US11052805B2
A console bin assembly for a vehicle includes a bin surface having a perimeter and a wall extending upward relative to the bin surface. A channel having a first end and a second end is located adjacent to the perimeter of the bin surface and the first wall. A drainage hole located near the first end of the channel. The channel is sloped such that the channel guides liquid entering the channel to the drainage hole.
US11052798B2
An air supply device and a method of operating same are provided for a vehicle seat having an air discharge opening provided in the upper region of the vehicle seat, via which opening a head, shoulder, and neck region of the seat occupant can be supplied with an airflow. The airflow is adjustable by a control unit for controlling or regulating a fan rotational speed of a blower and can be heated via a heating element. The control unit is supplied at least one activation signal for activating the air supply device and a temperature signal that provides information about the interior temperature. The control unit activates the heating element and the blower according to the activation signal and then controls at least the blower as a function of the interior temperature.
US11052797B2
A recliner heart includes a housing member, a locking plate and a pawl. The housing member includes a plate surface having a first recess and a second recess. The locking plate includes a surface having teeth formed thereon. The pawl is movable in the first recess between a secure position in which the pawl is engaged with the teeth of the locking plate and a release position in which the pawl is disengaged from the teeth of the locking plate. The pawl includes a boss slidably received in the second recess. A first lateral side of the boss abuts against a sidewall of the second recess upon an impact event.
US11052788B2
A longitudinal adjuster may have a first transverse locking bar accommodated in a slot of a first seat rail. A spindle may be guided through an opening of the first transverse bar in a contact-free manner. At a distance from the first transverse locking bar toward the front, a shoulder of the spindle is arranged. In reaction to a specified action of force, the first transverse locking bar is clamped between the first seat rail and the shoulder. As a result, a force from the first seat rail via the first transverse locking bar, the shoulder, the spindle, and the spindle nut can be diverted to the second seat rail.
US11052782B1
A charging system for a vehicle is provided. The charging system is for charging an energy storage system of the vehicle using grid power. The grid power may be an external three-phase AC. The charging system may use field weakening techniques to reduce a peak line-line voltage detected at input terminals of conversion circuitry when a need is determined.
US11052780B2
The vehicle dispatching system accepts a dispatch request from a user, selects an autonomous vehicle matching with the dispatch request from among a plurality of autonomous vehicles, and dispatches a selected autonomous vehicle to the user. The plurality of autonomous vehicles include a plurality of battery-mounted vehicles having an in-vehicle battery capable of being charged externally as an energy source. Each of the plurality of battery-mounted vehicles performs charging at a charging station when a charging level of the in-vehicle battery decreases. The vehicle dispatching system comprises a management server including a processor for executing programs stored in memory, the management server programmed to act as a charging planning unit that changes an upper limit charging level of the in-vehicle battery when charging at the charging station according to a time slot.
US11052774B2
A rail transit braking energy recovery system. The rail transit braking energy recovery system comprises a braking motor, a fuel battery, an electrolytic bath, and a hydrogen tank. The braking motor is used for converting braking energy of the rail transit into electric energy. An output end of the braking motor is connected to a power input end of the electrolytic bath. The electrolytic bath comprises a hydrogen output end and an oxygen output end, the hydrogen output end is connected to the hydrogen tank, and the hydrogen tank is connected to the fuel battery and is used for supplying hydrogen to the fuel battery. In the system, only the electrolytic bath is structurally added, and the existing vehicle-mounted hydrogen tank is directly used for storing hydrogen, therefore the structure is simple, the self weight of the vehicle body is reduced, the energy conversion efficiency is high, and at the same time, the injection of hydrogen is reduced and the operation cost is reduced. In addition, the purity of the hydrogen obtained by means of electrolysis is high, so that the hydrogen can be directly supplied to the fuel battery to be used without being processed. Also provided is a hybrid power rail transit system.
US11052772B2
Techniques are described for implementing automated control systems that manipulate operations of specified target systems, such as by modifying or otherwise manipulating inputs or other control elements of the target system that affect its operation (e.g., affect output of the target system). An automated control system may in some situations have a distributed architecture with multiple decision modules that each controls a portion of a target system, and may further have one or more components that interacts with one or more users to obtain a description of the target system, including restrictions related to the various elements of the target system, and one or more goals to be achieved during control of the target system. The component(s) then perform various automated actions to generate, test and deploy one or more executable decision modules to use in performing the control of the target system based on the user-specified information.
US11052765B2
A first and a second control device capable of transmitting and receiving signals to and from a third control device that performs an overall management to the control devices. The third device transmits a command signal to the second device in response to a reception signal from the first device. The first device transmits, to the second device and the third device, an electrical power storage unit signal includes at least one of control information and abnormality information about charging/discharging. The second device includes a function of controlling actuation of a rotating electrical machine on the basis of an actuation command signal about actuation of the rotating electrical machine transmitted from the third device in response to the electrical power storage unit signal, and a function of controlling actuation of the rotating electrical machine on the basis of the electrical power storage unit signal transmitted from the first device.
US11052760B2
A vehicle control device incorporating a plurality of vehicle control elements, at least one control apparatus to alter a functionality of the vehicle control elements, each of the vehicle control elements adapted in use to control a valve in a hydraulic line, in which each vehicle control element incorporates a vehicle control display element, the vehicle control display element indicating whether the functionality of the vehicle control element may be altered. This allows a driver when looking at the vehicle control element easily to see from the vehicle control display element whether the functionality of the vehicle control element may be changed.
US11052756B2
A drive device for a motor vehicle includes an electrical machine which is operatively connected to a transmission device via a drive shaft. The transmission device has at least a first and a second planetary stage and a differential stage. Each planetary stage includes a planet set having a plurality of planet gears, the planet gears being rotatably arranged on a planet carrier and meshing with a sun gear and with a ring gear. The second ring gear has external teeth which mesh with internal teeth of a ring gear cup fixed to a housing in a stationary manner.
US11052755B2
A capless fuel door assembly including a body pivotally supported within a housing of the vehicle between closed and opened positions. The body includes an exterior projection exhibiting an angled slide. A spring is secured to the housing and includes an extended portion supported against an end stop location of the projection defining a first end of said angled slide in order to exert the body in the closed position, with opening of the body about the pivot causing a decrease in the closing force as the spring portion displaces along said angled slide to a second end to achieve the opened position.
US11052753B2
A dual-fuel tank houses one or more compressed natural gas (CNG) vessels and one or more diesel fuel vessels. The diesel fuel vessels are generally disposed laterally outwardly from the CNG vessels to provide a buffer that protects the CNG vessels from side impacts. The dual-fuel tank may be retrofit onto a diesel locomotive in place of the locomotive's diesel fuel tank to convert the locomotive into a dual-fuel locomotive. The dual-fuel tank may be provided in a ship.
US11052752B2
A cooling apparatus for cooling compressed air produced by a compressor of a supercharger includes an air-cooled intercooler through which the compressed air flows, a grille shutter capable of blocking a flow of wind toward the intercooler, and a controller. The controller performs control processing to close the grille shutter when an ambient temperature around the intercooler is lower than or equal to zero degrees centigrade and a pressure value of the compressed air is lower than a predetermined pressure value at which condensate water generated within the intercooler is maintained in an unfrozen state at the ambient temperature lower than or equal to zero degrees centigrade, or otherwise performs control processing to open the grille shutter.
US11052746B2
A vehicle drive assembly with transverse dual-power-source, comprising two power sources and an automatic transmission. The automatic transmission has a first input shaft and a second input shaft, and the two power sources are respectively connected to the two input shafts; a first intermediate shaft is provided parallel to the first input shaft, a second intermediate shaft is provided coaxial with the first input shaft, a third intermediate shaft is provided coaxial with the first intermediate shaft, and a first gear and a second gear on the first intermediate shaft are in engaged transmission; a third gear shaft and a fourth gear on the second intermediate shaft are in engaged transmission; and a fifth gear and a sixth gear on the third intermediate shaft are in engaged transmission, and the sixth gear is simultaneously in engaged transmission with a seventh gear on a differential.
US11052744B2
A transmission having a main transmission and a splitter group, and including at least four spur gear planes formed with a countershaft and at least five shifting elements for engaging at least six gears between the transmission input and output shafts. When shifting between gears with the highest and the second-highest gear ratios, a shift occurs in the shifting elements associated with the splitter group but not in the shifting elements associated with the main transmission, whereas when shifting between gears with the lowest and second-lowest gear ratios, a shift occurs in the shifting elements associated with the main transmission but not in the shifting elements associated with the splitter group. An electric machine can be connected by a gearset, and depending on its shift position, the gearset acts as a pre-transmission ratio for the electric machine or as a superimposition transmission.
US11052743B2
A method according to an exemplary aspect of the present disclosure includes, among other things, periodically adjusting powertrain operation of an electrified vehicle equipped with an internal combustion engine to progressively influence oil quality of oil of the internal combustion engine.
US11052716B2
An axle for a vehicle, wherein the axle includes a transverse axle portion having a longitudinal end. The axle including a first axle portion connecting the transverse portion to a chassis of the vehicle and a second axle portion connecting the transverse portion to a wheel carrier for supporting a vehicle wheel. A vibration damper is arranged in a receiver in one of the axle portions.
US11052713B2
A mobility connection system including a left driveshaft and a right driveshaft having an internally hollow shaft shape, and connected to a left wheel portion and a right wheel portion, respectively; a connection shaft having a shaft shape provided inside the left driveshaft or inside the right driveshaft, and slid to the outside of a vehicle to be inserted into and coupled to the inside of the driveshaft of another vehicle which is disposed adjacent to the side thereof when the vehicle is laterally coupled to another vehicle; and a wheel detecting sensor provided at the left side or the right side of the vehicle, and for detecting whether the driveshafts facing each other when the vehicle is coupled to another vehicle have been aligned with each other or the spacing distance therebetween is formed.
US11052709B2
A pneumatic tire includes land portions defined by grooves, and sipes that are formed in the land portions and intersect the grooves. The sipes form acute angle portions and obtuse angle portions with the grooves. Notches are formed in the obtuse angle portions.
US11052708B2
A pneumatic tire includes: a protrusion portion projecting outward in a tire lateral direction disposed in a buttress portion; and a linear portion with a linear shape when viewed in a tire meridian cross section, the linear portion constituting a surface of the protrusion portion at a position inward in a tire radial direction from a corner portion, the corner portion being an end portion of the protrusion portion outward in the tire lateral direction; the corner portion being located within a retreading development width position, which is a range in the tire radial direction in which a boundary for removing a tread when retreading is located; and the linear portion having an angle ranging from 45° to 90° with respect to a horizontal line parallel with a tire rotation axis at a position inward of the linear portion in the tire lateral direction.
US11052706B2
A green tire includes a plurality of sheets of green rubber having a substantially circular shape, wherein each sheet of green rubber includes an upper ring and a lower ring, and each sheet of green rubber further includes a plurality of spoke portions extending from the upper ring to the lower ring. The green tire further includes a plurality of reinforcements. Each reinforcement is disposed between adjacent sheets of green rubber. At least one reinforcement is sandwiched between the upper rings of adjacent sheets of green rubber, and at least one reinforcement is sandwiched between the spoke portions of adjacent sheets of green rubber.
US11052693B2
The invention comprises a mechanical handwriting system linked to a user input system to generate a plotted document, such as a greeting card, note card or document, using a conveyor belt unit to support and move the document, a plotter, and a series of rollers to position and constrain movement of the greeting card, which is optionally and preferably linked to a paper feeder system in an assembly line format, where the rollers are optionally and preferably adjustable in position to accommodate varying paper sizes and to allow movement of the document during a plotting period to avoid positional overlap constraints of the rollers and a plotter head of the plotter in a process of plotting the document/card in sections.
US11052692B2
A covering assembly is disposed on an inked printing assembly of a stamp. The covering assembly has a top cover and a bottom cover. The top cover is detachably disposed above the inked printing assembly. The bottom cover is detachably disposed below the inked printing assembly, is located below the top cover at a spaced interval, and has a bottom wall. The covering assembly can assist in assembling the inked printing assembly. The disposition of the top cover and the bottom cover can transfer pointed force into planar force for increasing a contact area, the forcing uniformity, and the assembly convenience.
US11052691B2
Examples of the present disclosure relate to a calibration method for a printing system. The method comprises printing a diagnostic pattern representative of decap time. The diagnostic pattern comprises the firing of nozzles after an exposure to ambient air during a first predetermined time period to produce a first pattern element and the firing of nozzles after an exposure to ambient air during a second predetermined time period to produce a second pattern element. The method includes scanning the resulting diagnostic pattern with a sensor to collect decap data in a digital form, digitally analyzing the decap data, the digital analysis comprising identifying a quantitative difference between the first and second pattern elements, and modifying a servicing process of the printing system if the quantitative difference passes a predetermined threshold.
US11052683B2
A single nip de-skew, lateral registration, and process direction registration device removes skew, laterally registers, and registers in the process direction substrates moving along a media transport path. The single nip de-skew, lateral registration, and process direction registration device includes a fixed roller that is longer than a rotating wheel that forms a nip with the fixed roller. The wheel has a coefficient of friction that is higher than a coefficient of friction of the roller so an actuator translating the wheel along the fixed roller laterally registers and de-skews substrates.
US11052682B2
Devices and methods for identifying categories or types of print media in image forming apparatuses are disclosed. In an example method print media are advanced in a feeding direction to reach a cutting position, a cutter is advanced in a cutting direction, perpendicular to the feeding direction to cut the print media, friction between the cutter and the print medium is measured, and the print media are identified based on the measured friction.
US11052676B2
A printing device 1 includes a platen roller 7 which feeds a thermal tape 42, a thermal head 8 which performs printing on the thermal tape 42, and a control circuit 12. The control circuit 12 rotates the platen roller 7 backward to feed the thermal tape 42 backward in order to make a printing start area PT of the thermal tape 42 reach a backward feed position more away from an outlet 2b than a normal position NP of the thermal head 8. After that, the control circuit 12 rotates the platen roller 7 forward to perform printing using the thermal head 8.
US11052674B2
To reduce an influence of a flow of ambient atmosphere and the like on flying of a droplet ejected from a nozzle of an inkjet head. To exhaust vapor of a solvent contained in a coated film while reducing an influence on flying of the droplet. An exhaust device for inkjet coating includes: a cover that covers at least a target range on an object to be coated, the target range being a range in which a droplet lands that is ejected from an ejection nozzle of an inkjet head to a surface of the object to be coated; a closing member that closes a gap between the cover and the object to be coated around the target range; an external communication portion through which a compartment surrounded by the cover, the object to be coated, and the closing member communicates with an outside; and an exhaust mechanism configured to exhaust air from the compartment.
US11052669B2
In one example, an article for a replaceable printer component includes an integrated circuit device having a device controller, a conductor to supply power to the device controller and to carry a signal to and from the device controller, and a sensor operatively connected to the device controller to sense a voltage and/or a frequency on the conductor. The device controller to send an indication of a sensed voltage and/or a sensed frequency to the printer controller.
US11052666B2
In an example, a printhead carriage to be used in a printing system is disclosed herewith wherein the carriage includes a pocket defined by a first wall and a second wall opposite to the first wall; a set of electrical connectors provided on the first wall; and a mechanical protector. In an example, the mechanical protector may be a sheet with a determined length that extends from the first wall into the pocket and a width that extends along the width of the first wall over the electrical connectors. In an example, the mechanical protector includes an elastic member biased towards the second wall.
US11052664B2
A liquid absorbing device includes: a liquid absorber containing fibers and an anionic absorbent resin designed to absorb a liquid; a container having a feed port to which the liquid is supplied, a storage section that is connected with the feed port and that stores the liquid absorber, an inflow section configured such that part of the liquid flows into when the liquid is supplied to the storage section, and a communicating portion that connects the storage section with the inflow section; and a detection unit that is provided in the inflow section and that is configured to detect a surface of the liquid in the inflow section.
US11052659B2
There is provided a liquid discharge apparatus including: a discharging member including a plurality of individual electrodes arranged side by side in a first direction, a plurality of individual channels arranged side by side in the first direction, a plurality of nozzles arranged side by side in the first direction, a common channel communicating with the plurality of individual channels, and an opening communicating with the common channel; and a heating member at least a part of which makes contact with the discharging member. An individual electrode, included in the plurality of individual electrodes and located at an end in the first direction, and the opening are apart from each other in the first direction. At least the part of the heating member is a part making contact with the discharging member, at a location between the opening and the individual electrode located at the end in the first direction.
US11052653B2
A system for processing water washable flexo photopolymer printing plates, the system comprises a washing line including one or more brushes and a surface essentially facing said brushes, and a guiding means adapted to guide a water washable photopolymer printing plate through the washing line by pulling it from a vicinity of a downstream edge thereof and automatically dragging such water washable photopolymer printing plate on said surface. Said brushes are adapted to contact onto a side of such water washable photopolymer printing plate in a washing direction from the downstream edge towards an upstream edge thereof. The system further comprises one or more attachments adapted to be annexed to the vicinity of the upstream edge of a water washable photopolymer printing plate, the attachments being further adapted to exert friction onto the surface, said friction being greater than that between such water washable photopolymer printing plate and said surface.
US11052646B2
In a lining material peeling method of peeling a lining material, which is fixedly formed on a surface of a base material, from the base material, a liquefied fluid which evaporates after injection is injected to a boundary between the base material and the lining material.
US11052644B2
An electrical conductor includes: a first conductive layer including a plurality of ruthenium oxide nanosheets, wherein at least one ruthenium oxide nanosheet of the plurality of ruthenium oxide nanosheets includes a halogen, a chalcogen, a Group 15 element, or a combination thereof on a surface of the ruthenium oxide nanosheet.
US11052639B2
Thermoplastic film suitable as an intermediate layer for a laminated glass pane, wherein the thermoplastic film includes a defined region, which is provided for a camera window or an HUD (head-up display) region that has a non-zero wedge angle, and a region surrounding the defined region on all sides, in which the thermoplastic film has a substantially constant thickness, wherein the maximum thickness in the defined region of the thermoplastic film is less than the thickness in the surrounding region.
US11052637B2
A structure containing a Sn layer or a Sn alloy layer includes a substrate, a Sn layer or Sn alloy layer formed above the substrate, and an under barrier metal formed between the substrate and the Sn layer or Sn alloy layer in the form of a single metal layer containing any one of Fe, Co, Ru and Pd, or an alloy layer containing two or more of Fe, Co, Ru and Pd.
US11052635B2
Provided is a sheet-type molded body that is formed by sewing a sheet, wherein thread is used for at least part of said sewing, the thread being composed of a resin composition for thread containing resin for thread, the thread having a melting point of no more than 200° C., and a laminate comprising: the sheet-type molded body; and a polyurethane foam formed body, the sheet-type molded body, and the laminate comprising: the sheet-type molded body; and a polyurethane foam layer being able to be produced by a simple method at low cost without damaging design qualities over time, and making it possible to prevent leakage of raw material etc. from sewed portions when backed with the polyurethane foam layer.
US11052632B2
An article comprising a flexible mesh layer pliable enough for being arranged in direct planar contact with a contoured surface, the mesh layer providing one or more attributes of adhering, sealing or reinforcing to a surface receiving the flexible mesh.
US11052630B2
A sheet processor subjecting a sheet having been conveyed forward to processing along a direction perpendicular to a conveyance direction of the sheet, includes: a processing unit performing the processing; and a receiving unit receiving the processing unit therein in a state capable of perfecting the processing on the sheet, and the processing unit includes a first processing tool 4A and a second processing tool 4B disposed to vertically oppose each other with a conveyance surface of the sheet disposed therebetween, and the receiving unit includes at least one receiver that removably receives the first processing tool 4A and the second processing tool 4B in the state capable of performing the processing on the sheet, with arbitrarily selected one of the first processing tool 4A and the second processing tool 4B disposed above the conveyance surface, and with arbitrarily selected another of the first processing tool 4A and the second processing tool 4B disposed below the conveyance surface.
US11052628B2
A bag making and packaging machine has pull-down belt mechanisms, a transverse sealing mechanism, a rotatable folding member, and a gas blowing mechanism. The folding member, before the transverse sealing mechanism, seals a cylindrical film, pushes against a side portion of the cylindrical film to thereby fold the cylindrical film inward and form a fold in the cylindrical film. The gas blowing mechanism blows a gas onto the fold to thereby inhibit the cylindrical film from sticking to the rotating folding member.
US11052620B2
A guiding device for guiding a fiber texture on an impregnation mandrel of a winding machine, the device including a first radial spacer for placing facing a first cheekplate of the impregnation mandrel, a second radial spacer for placing facing a second cheekplate of the impregnation mandrel, and a cross-member suitable for supporting the first and second spacers, the cross-member including an adjustment system for adjusting the positions of the first and second spacers and suitable for positioning the first and second spacers apart respectively from the first and second cheekplates of the impregnation mandrel so as to hold a first portion of fiber texture that extends along the first cheekplate pressed against the first cheekplate, and a second portion fiber texture that extends along the second cheekplate pressed against the second cheekplate, without blocking rotation of the impregnation mandrel.
US11052616B2
A method for manufacturing a multilayer fiber structure includes providing a receiving surface being formed by a first surface region of a contoured tool surface of a forming tool component and a support surface of a support component. Further, at least one fiber layer is formed on the receiving surface by laying down a plurality of fiber tapes onto the receiving surface. A roller device is positioned so as to press the at least one fiber layer against the tool surface and the support component and the roller device are synchronously moved along a curved transition region connects the first surface region to a second surface region of the tool surface. Thereby the at least one fiber layer is abutted against the transition region and the second surface region of the tool surface. Further, a tool system for manufacturing a multilayer fiber structure is disclosed.
US11052611B2
A fabricating apparatus includes processing circuitry. The processing circuitry is configured to receive designation of a scheduled fabrication start time of a fabrication object, detect a change in a fabrication practicability condition of the fabricating apparatus, and output change information indicating an occurrence of a change in the fabrication practicability condition of the fabricating apparatus when the change in the fabrication practicability condition has been detected after reception of the designation of the scheduled fabrication start time.
US11052610B2
A powder delivery device for providing raw material powder to a powder application device of a powder bed fusion apparatus is provided. The powder delivery device comprises a powder supply section configured to receive raw material powder, the powder supply section comprising an outlet for providing the raw material powder to the powder application device. The powder delivery device further comprises a first physical parameter determining unit arranged at a first location of the powder supply section and configured to determine a first physical parameter in the powder supply section, and a controller configured to determine whether the first physical parameter meets a first tolerance criterion, and a powder treatment unit. The controller is configured to instruct the powder treatment unit to perform a powder treatment in case it determines that the first physical parameter does not meet the first tolerance criterion.
US11052603B2
An additive manufacturing system is disclosed for use in fabricating a composite structure. The additive manufacturing system may include a print head configured to discharge a continuous reinforcement that is at least partially wetted with a matrix, and a support configured to move the print head in at least one dimension during discharge. The additive manufacturing system may also include a cutting mechanism connected to at least one of the print head and the support. The cutting mechanism may be configured to selectively sever the continuous reinforcement from the print head. The cutting mechanism may include a cutting implement, a first actuator configured to move the cutting implement from a stowed position to a deployed position, and a second actuator configured to engage the cutting implement with the continuous reinforcement.
US11052601B2
In a 3D-printing system, a deposition head comprising a band assembly having a body and a band for compacting a filament onto the surface of an object being manufactured. One or more actuators are mounted on the assembly body and are used to shape the band to a desired contour. The band is connected to the one or more actuators, is curved toward the surface of the object to enable contact with the surface, and is capable of being driven along its length by one or more drive wheels that are under the control of a controller. The drive wheels are configured to advance the band along its length by a first distance and in response to a first signal from the controller. The controller provides the first signal based on an estimate of thermoplastic build-up on a portion of the band that overlaps the point of compaction.
US11052597B2
Described is a method of forming a structure having viscoelastic properties. The method can include a) depositing a layer of droplets of a solidifying material and a non-solidifying material, the droplets being deposited according to an occupancy matrix specifying voxels for the solidifying and non-solidifying materials, the solidifying and non-solidifying material being interspersed within the occupancy matrix, the occupancy matrix being generated by a probabilistic function; b) exposing the droplets of solidifying material to ultraviolet radiation to cure the solidifying material; and c) repeating a) and b) to deposit additional layers of droplets of solidifying and non-solidifying materials, thereby forming the structure having viscoelastic properties.
US11052592B2
An extruder assembly has a frame with upstream and downstream ends. A barrel assembly on the frame has a passage. At least one material advancing component resides at least partially within the passage and is configured to be turned around an operating axis to thereby cause material to be conveyed from a passage inlet to a passage outlet. A drive assembly turns the at least one material advancing component around its operating axis and has a motor on the frame situated so that at least a part of the motor is in lengthwise overlapping relationship with the barrel assembly. The drive assembly is configured to turn the one material advancing component around its operating axis at a speed of at least 300 rpm.
US11052578B2
A method for producing a thermoplastic combination film suitable for a composite glass pane, wherein the thermoplastic combination film includes at least one defined area, which is provided for a camera window or an HUD (head-up display) region that has a variable wedge angle, the method including providing a first thermoplastic film, producing a second thermoplastic film with a variable wedge angle, wherein the three-dimensional shape of second thermoplastic film is obtained by molding on a mold, and joining together the first thermoplastic film and the second thermoplastic film.
US11052575B2
Disclosed is an elastomeric bladder tool and related systems and methods. In one embodiment, the elastomeric bladder tool comprises an elastomeric inner layer substantially defining an inner cavity of the elastomeric bladder tool, an elastomeric outer layer substantially defining an outer surface of the elastomeric bladder tool, and a permeable middle layer positioned between the elastomeric inner layer and the elastomeric outer layer. The permeable middle layer has greater permeability than both the elastomeric outer layer and the elastomeric inner layer to allow for evacuating of gases that have entered the permeable middle layer.
US11052572B2
Systems for and methods of forming structural components, such as a spar cap (503), from layers of a fiber reinforced material obtained from rolls of the material are disclosed. The system comprising: a plurality of rolls (514) including a first roll (514a) and a second roll (514b) of the fiber reinforced material (504), the first roll has one or more first lines (530) printed thereon. The first lines indicating where the fiber reinforced material on the first roll is to be separated into a plurality of discrete first pieces (531-1) for forming the structural component (503). The fiber reinforced material on the second roll has one or more second lines (530) printed thereon. The second lines indicating where the fiber reinforced material on the second roll is to be separated into a plurality of discrete second pieces (531-2) for forming the structural component (503). The systems and methods achieve a substantial reduction in the amount of wasted material.
US11052571B2
Systems and methods are provided for fabricating preforms for composite parts. One embodiment is a method of creating a preform. The method includes conveying a web of fiber reinforced composite material in a process direction, disposing fiber reinforced composite material atop the web, conveying the web and the tow in the process direction to a cutting tool, and cutting out a preform comprising a combination of the tow and the web.
US11052570B2
A process for producing foamed thermoplastic polyurethane particles comprises the steps of a) melting a thermoplastic polyurethane in a first extruder (E1), b) injecting a gaseous blowing agent in a second extruder (E2), c) impregnating the gaseous blowing agent homogeneously into the thermoplastic polyurethane melt in a third extruder (E3), d) extruding the impregnated thermoplastic polyurethane melt through a die plate and granulating the melt in an underwater granulation device under temperature and pressure conditions to form foamed thermoplastic polyurethane particles.
US11052566B2
A pole for supporting a cable. The pole includes a plurality of truncated cones arranged in a linear array to form the pole, wherein each truncated cone receives an adjacent truncated cone within its interior. Each truncated cone in the pole is formed from a veneer by moving the longitudinal edges of the veneer towards each other. A method of manufacturing the pole and various uses of the pole are also provided.
US11052557B2
A razor includes one or more blades that are directly or indirectly heated by RF energy. A control circuit is connected to and operates a high frequency (HF) generator and a HF power amplifier (HFPA) for generating radio frequency (RF) energy throughout a range of controllable power levels. The generated RF energy is guided by a wave guide from the HFPA to a resonance chamber (i.e., band pass filter cavity). The RF energy is radiated from the resonance chamber towards the one or more blades which absorb the RF energy, thereby causing the temperature of the blades to increase. An energy source provides the electric current required for operating the control circuit, the HF generator and the HFPA. In another embodiment, the RF energy is radiated from the resonance chamber towards a heating element that increases in temperature and heats the blades by thermal conduction.
US11052552B2
A safety blade for use with a knife assembly comprises a blade body, a bade attachment having a cutting edge and a top edge opposite the cutting edge, a blade attachment having a first half and a second half connected together via a hinge and extending beyond the top edge of the blade body to define a clamshell for receiving the blade body, and a handle adaptor having a handle engagement portion for removably securing the blade attachment to a handle.
US11052543B2
A control device includes a control section configured to control a motion of a robot arm using values detected by a plurality of distance sensors. The plurality of distance sensors include a first distance sensor and a second distance sensor disposed in a first direction orthogonal to the axial direction of a dispenser. The second distance sensor is disposed in a position further apart from the dispenser than the first distance sensor. The control section executes, on a robot, a first instruction for causing the robot to execute discharge of a discharge object by the dispenser when a distance acquired by the first distance sensor is a distance in a predetermined range and a distance acquired by the second distance sensor is a distance larger than the distance in the predetermined range.
US11052539B2
Method, server and storage medium for robot routing are provided. An operation area of the robot is gridded into a plurality of cells arranged in rows and columns. The method includes: planning, for the robot, a traveling path from a starting point to a destination point, where the traveling path is divided into a plurality of path segments; and reserving, one or more cells corresponding to a first path segment for the robot, where the first path segment is anyone of at least one among the plurality of path segments, in case that there is the deadlock phenomenon, refraining from reserving the cell for the robot, and re-checking whether the deadlock phenomenon is still present in the cell after a preset interval; and in case that there is no deadlock phenomenon, reserving the cell for the robot.
US11052525B2
A hammer drill includes a housing, a tool holder, a hammering member, a gear, and a conversion member. The gear is switched to a first state where a rotation of the intermediate shaft is transmitted and a second state where the rotation of the intermediate shaft is not transmitted, and a mode switching member is configured to perform a switching operation of the state of the gear from an outside of the housing. The switching of the state of the gear by the mode switching member provides at least two operation modes of a hammer drill mode where the gear integrally rotates with the intermediate shaft to generate the rotation and a reciprocation of the hammering member on the tool holder and a hammer mode where the gear is separated from the rotation of the intermediate shaft to generate only the reciprocation of the hammering member.
US11052521B2
A crimping device includes a housing defining a bore and at least three extendable mechanisms angularly equispaced about the axis of the bore. Each of the extendable mechanisms include: (i) a first elongate arm hingedly connected at or near a first axial end of the first arm to the housing; (ii) a second elongate arm hingedly connected at or near a first axial end of the second arm to the housing, wherein: the first axial ends of the first and second arms are displaceable relative to each other; and the first and second arms are hingedly connected at or near their second axial ends to each other. The crimping device further includes means for equi-displacing the first axial ends of coupled first and second arms relative to each other, thereby to configure the crimping device between: (i) a dilated condition in which the second axial ends of the first and second arms are maximally spaced from the bore axis; and (ii) a contracted condition in which the second axial ends of the first and second arms are minimally spaced from the bore axis.
US11052518B2
A liner 7 is provided with a cylinder portion 14a is formed in parallel to the rotation axis, and also a hydraulic fluid flow path 14c is formed which opens to a cylinder portion 14a to communicate with the interior of the liner serving as a high-pressure chamber and a low pressure chamber at the time of occurrence of the striking torque, and an automatic relief mechanism 14 is provided in which a cylindrical valve element 14b having a cutout portion 14b′ serving as a flow path for hydraulic oil formed on the outer peripheral surface portion is disposed inside the cylinder portion 14a so as to be freely rotatable.
US11052515B2
The 90 Degrees utilizes dual ratio constant mesh gears which provides suitable use for ratchets in hard to access spaces, and particularly well suited for automotive use. The mesh gears are configured to be used either with manual or pneumatic tools. A female socket element recedes into the housing having gears therein and a male socket element meshes with the female socket element and is shaped to accommodate a female socket element at 90 degrees or the adapter element of a drive ratchet. You can use an elongated drive shaft to accommodate distance. Positioned within the housing of the adapter body are gears secured to mesh within the housing of the adapter. Rotation of the female socket element by a drive ratchet in one direction will rotate the male socket element in the opposite direction without any change in direction is governed by the ratchet use.
US11052513B2
A pneumatic-fixation connecting having a body, a movable part, a plurality of spheres, a plurality of elastic units, and a plurality of stop units is disclosed, wherein each of the elastic units is disposed between the body and the movable part via each of the stop units, respectively. When an external force is applied on the movable part, the distance between the movable part and the body is reduced and the sphere does not block the connecting pin in the extension tube inside the body. When the external force disappears, the distance between the movable part and the body increases such that the sphere affixes the connecting pin and the body. The stop unit can be used, not only to adjust the length and elastic force of the elastic unit so as to extend the life cycle of the elastic unit, but also to help in changing the elastic unit which in turn enhances the efficiency of the replacement work.
US11052504B1
A temperature regulation system and a temperature regulation method are applicable to a machine tool. The temperature regulation system includes a cooling fluid storage tank, a heating fluid storage tank, an internal circulation subsystem, an external circulation subsystem and a computing unit. The internal circulation subsystem includes a first valve. The external circulation subsystem includes a plurality of flow channels and a second valve and a third valve disposed on the plurality of the flow channels. The computing unit controls the first valve, the second valve and the third valve to switch flow directions of the plurality of the flow channels among the cooling fluid storage tank, the heating fluid storage tank and machine tool. Therefore, a thermal balance of the machine tool can be effectively maintained.
US11052481B2
A method for processing a transparent workpiece includes directing a pulsed laser beam into the transparent workpiece such that a portion of the pulsed laser beam directed into the transparent workpiece generates an induced absorption within the transparent workpiece, thereby forming a damage line within the transparent workpiece, and the portion of the pulsed laser beam directed into the transparent workpiece includes a wavelength λ, a spot size w0, and a Rayleigh range ZR that is greater than F D π w 0 2 λ , where FD is a dimensionless divergence factor comprising a value of 10 or greater. Further, the method for processing the transparent workpiece includes etching the transparent workpiece with an etching vapor to remove at least a portion of the transparent workpiece along the damage line, thereby forming an aperture extending through the at least a portion of the thickness of the transparent workpiece.
US11052477B2
A slag removal apparatus for removing slag from support plates provided to support an object to be processed in a cutting machine is disclosed. The slag removal apparatus includes a scraper including a plurality of blades around an outer surface of a bar crossing the support plates, and a plurality of slots formed in the respective blades along a length direction and thus formed around the bar and in a length direction of the bar, a rotation support unit to which the scraper is rotatably installed, a rotation driving unit rotating the scraper from the rotation support unit to remove slag attached to the support plates by the blades, when the support plates are inserted into the slots, a lifting unit lowering the scraper, for insertion of the support plates into the slots and raising the scraper to an original position by raising and lowering the rotation support unit, and a first transfer unit moving the rotation support unit along a length direction of the support plates to allow the scraper to remove the slag along the length direction of the support plates.
US11052472B2
A cutting insert includes a rake face configuring one of polygonal surfaces, a seating surface configuring the other one of the polygonal surfaces, and a side surface connecting the rake face and the seating surface to each other. The cutting insert has a cutting edge portion including a main cutting edge located in a side portion of the rake face, a subsidiary cutting edge connected to the main cutting edge, and a corner cutting edge connected to the subsidiary cutting edge and located in a corner portion of the rake face. The side surface includes a flank face and a connection surface which are adjacent to each other in a thickness direction via a boundary line. The connection surface is located on the seating surface side, and is located outside than an extension line of the flank face.
US11052470B2
THIS invention relates to a drilling accessory for a power drill drilling accessory that assists the operator of the power drill to correctly align and orientate the drill bit of the power drill with the target object, and collects the dust and/or debris arising from such drilling. The drilling accessory includes a cap having a plurality of differently sized guide holes and a container to which the cap is pivotally connected. The container comprises a first through hole, which on rotation of the cap relative to the container, enables the first through hole to be aligned with the require guide hole thereby to allow a drill bit to pass therethrough. The container further comprises a base having a planar support surface portion and a seal portion protruding outwardly from the support surface portion towards a contact lip, which contact lip defines a second through hole coaxially aligned with the first through hole. The protruding seal portion defines a bore therein tapering radially inwardly from the planar surface portion of the base towards the contact lip, which in use biases the contact lip into sealing engagement with the target object to efficiently collect dust and debris, with substantially the entire planar support surface portion contacting the target object thereby to provide a stability for drilling straight holes.
US11052468B2
A surface roughening tool includes a cylindrical body and at least one grooving blade outwardly radially projecting from the body and configured to form grooves and peaks into a surface. The surface roughening tool also includes at least one swaging blade outwardly radially projecting from the body and configured to deform the peaks. The at least one swaging blade is aligned with the at least one grooving blade along a circumference of the body.
US11052462B2
An additive manufacturing product is provided. The additive manufacturing product includes an embedded electronic, a transition zone, and a base material. The transition zone encases the embedded electronic. The transition zone includes transition material. The base material encases the transition zone. The transition material includes an intermediate melting point that is lower than a melting point of the base material.
US11052445B2
A method of forming a part includes extruding a billet through a die, forming a round, closed geometry tube from the billet, and hydroforming the round, closed geometry tube. The extrusion die contains an orifice with a central mandrel, a plurality of bridges, and a corresponding plurality of portholes between the bridges. A spacing of the bridges around the mandrel is non-equiangular. As a result, the round, closed geometry tube has non-equiangular welds after emerging from the die.
US11052442B2
To provide a copper-coated magnesium wire which meets the demand for a lightweight coil wire material, and a method for manufacturing the same. The above-described problem is solved by a copper-coated magnesium wire (10) comprising a core material (1) made of magnesium, and a copper coating layer (2) made of copper or a copper alloy provided on a surface of the core material (1). In the copper-coated magnesium wire (10), a wire drawing mark is present on a surface of the copper coating layer (2), and the diameter is preferably within a range of 0.03 to 0.08 mm, inclusive. Further, a thickness of the copper coating layer (2) is preferably within a range of 5 to 30%, inclusive, as a ratio of the overall cross-sectional area. An insulating coating layer (3) may be provided on an outer circumferential side of the copper coating layer (2).
US11052433B2
An ultrasonic cleaning equipment (1) according to the present invention includes a treatment tank (10) that stores a cleaning liquid that cleans an object to be cleaned and in which the object to be cleaned is immersed; an ultrasonic application mechanism (20) that applies ultrasonic waves to the cleaning liquid retained in an interior of the treatment tank; and a curved surface member (30) that is located in a range defined by an angle of inclination from a perpendicular direction in an end portion of a vibrating surface of the ultrasonic application mechanism to an outside with respect to the vibrating surface and that is held on a wall surface and/or a bottom surface of the treatment tank.
US11052412B2
A sprayer includes a spray gun and a hopper. An air source provides compressed air to the sprayer to both eject fluid from the spray gun as a spray and to pressurize the hopper. The spray gun includes an airflow controller for controlling the flow of the compressed air to a nozzle of the spray gun, a pressure regulator for regulating a pressure of the compressed air flowing to the hopper, and a relief valve between the pressure regulator and the hopper. The hopper receives the compressed air through a port in the hopper, and the compressed air assists the flow of material out of the hopper and into the spray gun.
US11052411B2
A nozzle device and method for creating a fluid nucleation in situ, is disclosed. The nozzle has a housing having a hollow interior, an outer cylindrical wall, and inlet and an outlet, and a diffuser disposed in the cylindrical tube at a first end toward the inlet. The diffuser is configured to break bonds between adjoining fluid molecules and create a nucleation event. The nozzle further has a mesh framework disposed in the cylindrical tube and extending longitudinally within the tube in the nucleation zone, and is configured to manipulate the bonding and un-bonding of water molecules within a pressurized environment for the production of snow, clean water or both.
US11052407B1
A dielectrophoresis-based in-droplet cell concentrator is disclosed herein. The concentrator can include a concentration microchannel having an input port and two or more outlet ports. The input port introduces cell-encapsulated droplets or particle-encapsulated droplets into the microchannel; a first outlet port receives droplets including most of the cells or particles and a second output port receives droplets including few cells or particles. The concentrator also can include a pair of electrodes. When voltage is applied, the electrodes will create an electric field across the microchannel. The concentrator adds new capabilities to droplet microfluidics operations, such as adjusting concentrations of cells in droplets, separating cells of different properties from inside droplets, and solution exchange.
US11052404B1
An apparatus for remediation of a copper and nickel co-contaminated soil includes a housing. A crushing device is arranged at the upper part of the inside of the housing. A stirring device is arranged below the crushing device. An anode electrode and a cathode electrode are provided at both ends of the inner bottom of the housing, respectively. In the present invention, the soil contaminated by copper and nickel is first poured from the top of the crushing device, and then crushed thoroughly under the action of the crushing device. The crushed soil facilitates the movement of copper and nickel metal ions therein toward the electrodes under the action of the anode electrode and the cathode electrode, thereby achieving optimal soil remediation.
US11052403B2
A protection device for tools for cutters and shredders and the like, arranged on a tool-holder seat for a tool-holder rotor rotatable about the axis of the rotor, said tool being housed in a seat arranged on the tool-bolder rotor, and formed by a first surface arranged at the front in the cutting direction and a second surface onto which the tool is fixed with its opposite surface to the cutting direction, the tool having a body that has a front surface in the rotation direction of the rotor, and a rear surface opposing the front surface. The tool and/or the seat having lateral projections and a protection device is dismountable connected to the seat of the tool, laterally as a protection for the tool and the plates being arranged partially between the lateral projections, of the tool and/or the seat of the tool, and the tool-holder rotor.
US11052399B2
A powder gathering apparatus includes at least two rotating plates and a driving mechanism. The at least two rotating plates are disposed with respect to each other. Each of the rotating plates includes at least one spherical member. The at least one spherical member protrudes from the rotating plate. The driving mechanism drives at least one of the at least two rotating plates to move, such that the at least two rotating plates get close to or away from each other. The driving mechanism drives the at least two rotating plates to rotate.
US11052391B2
A microfluidic device, including a controllable shape-changing micropillar where a shape of the shape-changing micropillar is changed by a fluid.
US11052388B2
A method of manufacturing a microfluidic device, said method comprising placing a length of material in a liquid polymer, configuring the length of material to define the path of a microfluidic channel, curing or setting the polymer liquid to form a solid polymer around the configured length of material, and dissolving the configured length of material with a solvent to provide a microfluidic channel in the solid polymer.
US11052381B2
A modified Y-type molecular sieve has a rare earth oxide content of about 4% to about 12% by weight, a phosphorus content of about 0% to about 10% by weight, a sodium oxide content of no more than about 1.0% by weight, a total pore volume of about 0.36 to 0.48 mL/g, a percentage of the pore volume of secondary pores to the total pore volume of about 20% to about 40%, a lattice constant of about 2.440 nm to about 2.455 nm, a percentage of the non-framework aluminum content to the total aluminum content of no more than about 10%, a lattice collapse temperature of not lower than about 1060° C., and a ratio of Brønsted acid to Lewis acid of no less than about 3.50. The preparation of the molecular sieve includes ion-exchange with rare earth, hydrothermal roasting, gas phase ultra-stabilization, acid treatment, and an optional phosphorus modification.
US11052376B2
The present disclosure provides for a porous gas sorbent monolith with superior gravimetric working capacity and volumetric capacity, a gas storage system including a porous gas sorbent monolith of the present disclosure, methods of making the same, and method for storing a gas. The porous gas sorbent monolith includes a gas adsorbing material and a non-aqueous binder.
US11052373B2
The present invention relates to processes and apparatus useful for (fast) ionic polymerisation of liquid monomer(s) containing reaction mixture for the production of the corresponding polymer(s).
US11052362B2
A device for spherification of a liquid includes a first device for storing a first liquid; and a spherification tank for storing a second liquid, arranged so that a dripper or entry funnel controls a level of the second liquid in the spherification tank. A device meters the first liquid coming from the first tank into the spherification tank. An extraction device extracts spheres generated in the spherification tank as a result of the metering. The extraction device includes a worm screw located in the spherification tank, the worm screw being arranged at an angle to the level, and a motor for rotating the worm screw.
US11052360B2
A mixing machine includes a head extending over a bowl receiving location, the head including a downwardly extending rotatable output shaft for receiving a mixer tool. A drive train including a motor having an output operatively connected to drive a planetary gear system that effects rotation of the rotatable output shaft about its axis and orbiting of the shaft axis about another axis. A control system includes a master control unit and a slave control unit, the master control unit connected with a first sensor located along the drive train between the motor and the planetary gear system, the slave control unit connected with a second sensor, wherein both the slave control unit and the second sensor rotate with a part of the planetary gear system, wherein the master control unit and the slave control unit are configured for wireless communication with each other.
US11052357B2
The invention relates to a stirring member (9) for using in a system for preparing a food product, the product being prepared by the stirring member (9) moving inside a container (8), the stirring member (9) being configured in such a way that it can adopt different configurations depending on its direction of rotation inside the container (8). Preferably, the stirring member (9) can adopt a spoon configuration or a whisk configuration. The invention further relates to a method for using such a stirring member (9) in a system for preparing a food product, the method varying the direction of rotation of the stirring member (9) so that it adopts a different configuration depending on the type of product prepared in the container (8).
US11052328B2
A fuel stabilization system for removing oxygen from fuel includes an accumulator disposed along a fuel line, the accumulator includes a fuel inlet and a fuel outlet and a heat source disposed in thermal communication with the fuel in or upstream of the fuel inlet of the accumulator to increase the temperature of the fuel within the accumulator. The accumulator is configured to allow oxygen deposits to form therein as a result of the temperature increase of the fuel.
US11052325B2
Provided are a mono-ethylene glycol (MEG) recovery apparatus and a MEG recovery method. The MEG recovery apparatus includes a pretreater receiving the raw material from a raw material supplier to remove the low soluble salts, a first distiller connected to the pretreater to receive the raw material from which the low soluble salts are removed, and to form a first treated solution by vaporizing a certain amount of the water, a high soluble salt remover connected to the first distiller to remove the high soluble salts from the first treated solution, a second distiller connected to the high soluble salt remover to form a second treated solution by vaporizing the water from the first treated solution from which the high soluble salts are removed, and a recovery unit connected to the second distiller to recover the second treated solution.
US11052321B2
A system that collects, analyzes, and applies physical metrics from participants in game environments. Participants (players and/or spectators) in a game may wear or hold devices that collect physical data from the participants via sensors, generate metrics data from the sensor data, and provide the metrics data to a participant metrics module. The module may receive the metrics data from the devices, analyze the metrics data to generate game inputs based on the participants' physical metrics, and provide the game inputs to the game system to affect game play. The module may also receive alerts or other information from the game system or from players, determine feedback for participants according to the received information, and signal the devices to provide feedback or alerts to the participants in the game. The devices may include indicators that are activated by the signals to provide visual, audio, and/or haptic indications to respective participants.
US11052313B2
Methods and systems for assigning a data center to service a request from a user account include receiving a login request to a cloud gaming server. The login request is examined to identify a user account. A use history of the cloud gaming server is examined to identify a data center. The user account is assigned to the data center to start a session of streaming game play at a server within the data center. The data center is identified without performing a connection testing operation.
US11052310B2
Various game controller hardware and user interface configurations are disclosed. Some configurations may comprise two circular trackpads, driven by the player's thumbs, which may be clickable, allowing the entire surface to act as a button. Haptic feedback may be based on dual linear resonant actuators (e.g., by means of strong, weighted electro-magnets attached to each of the dual trackpads), capable of delivering a wide range of force and vibration, allowing control over frequency, amplitude, and direction of movement. The haptics-related components in certain implementations may also play audio waveforms and thereby function as speakers. In the center of the controller according to certain configurations may be another touch-enabled surface, this one backed by a display screen. In some configurations this entire screen itself may also be clickable, like a large single button. A variety of other exemplary implementations and configurations are described.
US11052307B2
Embodiments of the present disclosure provide a method for controlling the movement of a virtual object performed by an electronic device. A first button is displayed at a first position of a screen. A second button is displayed at a second position of the screen when a first touch operation is detected. When a second touch operation on the second button is detected, a virtual object is controlled to move automatically, and the two buttons are highlighted. The automatic movement of the virtual object and the linkage between the two buttons are implemented through simple operations, thereby improving the convenience and flexibility of operations.
US11052304B2
A system that manages a package of shuffled playing cards and gaming chips includes a storage box and a control apparatus. The storage box is provided in association with a game table and stores a plurality of shuffled playing cards and a plurality of chip cases and also includes a card reader that reads playing card ID codes of the shuffled playing cards and a chip reader that reads case ID codes of the chip cases. The control apparatus outputs total numbers of the shuffled playing cards and the chip cases stored in the storage box and the playing card ID codes and case ID codes stored in the storage box by monitoring read playing card ID codes and case ID codes.
US11052299B2
A golf putter that enables dual configuration, namely sighting & play modes whereby the golfer can view both the ball and the hole by means of a mirrored surface, but which is reversible so that the golfer can play within tournament rules. A removable mirrored training aid has a reflective side and can be removed, flipped to a non-reflective side, or simply replaced with a same-weighted non-reflective plate, for use in actual (non-practice) golf play. The golfer can practice his or her stroke while observing the image of the ball and hole in the mirror, and thereby imprinting the correct stroke mechanics into muscle memory. Then, after the golfer has reversed the re-attachable mirrored surface plate to present its non-reflective side, the golfer can use the putter in a round of golf.
US11052296B2
A gymnasium or playing field game apparatus provides one or more movable target components in the shape of a mascot mounted on swivel casters which roll on the gym floor or other playing field. Each component serves as a movable target for projectiles thrown by two teams from geometrically opposite sides. Each mascot is moved incrementally upon being impacted by a projectile to move the mascot on the gym floor until it “breaks through” a designated goal finish line of traffic cones protecting one team or the other.
US11052288B1
A force measurement system is disclosed herein. The force measurement system includes a force measurement assembly configured to receive a subject thereon, and one or more data processing devices operatively coupled to the force measurement assembly. In one or more embodiments, the one or more data processing devices are operatively coupled to the force measurement assembly, the one or more data processing devices configured to receive one or more signals that are representative of forces and/or moments being applied to a top surface of the force measurement assembly by the subject, and to convert the one or more signals into output forces and/or moments, the one or more data processing devices further configured to predict one or more balance parameters of the subject using a trained neural network.
US11052284B2
The present invention relates to a method, system, and non-transitory computer-readable recording medium for supporting photographing of a golf swing. According to one aspect of the invention, there is provided a method for supporting photographing of a golf swing, the method comprising the steps of: (i) determining a user device matched with information on a user who is to perform a golf swing, among a plurality of user devices, with reference to a scenario associated with the golf swing; and (ii) causing a photographing module of the determined user device to photograph the golf swing of the user.
US11052278B2
A pipe exercise device designed to allow a user to transport a weight variable exercise device. The pipe exercise device includes an elongated member with an outer shell having a hollow interior designed to receive items therein. The elongated member has an open end disposed opposite a sealed end, wherein the open end is in communication with the hollow interior, such that a weight can be received therethrough to sit within the hollow interior. An end cap is designed to seal the open end, such that the weights therein are removably secured. At least one handle is disposed on the outer shell, such that the user can grasp the pipe exercise device. In this way, a user is able to transport a weight training device that can quickly and simply change the amount of weight used.
US11052272B2
A multiple position adjustable exercise device includes a first plate, a second plate and an elastic member. The second plate is pivotally connected with the first plate. The elastic member is disposed between the first plate and the second plate, and when the second plate rotates relative to the first plate, the elastic member is twisted for providing an elastic recovering force. An initial position of the second plate relative to the first plate is adjustable for adjusting the elastic recovering force.
US11052269B1
An improved protective face mask used to filter out hazardous pollution and airborne germs and viruses. Embodiments include a three layer version including a first spunbond TETHYS SHIELD treated layer, a meltblown filtration layer, and a second spunbond layer; a four layer version further including a gasket layer formed of a felt material; and a five layer version further including an activated carbon layer in between the spunbond TETHYS SHIELD treated layer and the meltblown filtration layer.
US11052266B2
Apparatus for measuring radiation beam energy output from a radiation beam source, comprising a first beam energy sensor at a first distance from the radiation beam source along the radiation beam axis; a second beam energy sensor located at a second distance from the radiation beam source along the radiation beam axis; and an energy absorbing layer, for example a layer that removes a part of the low energy content of the beam or a layer that absorbs at least 1% of the beam energy, located between the first and second sensors, and positioned such that radiation passing through the first sensor also passes through the energy absorbing layer before entering the second sensor.
US11052262B1
A method of affecting a biological, cellular or biochemical function or structure in a targeted subcortical location in a brain of a patient using a TRPMS apparatus placed on a head of the patient includes positioning two or more of a plurality of magnetic assemblies on locations of the head mount selected to stimulate the targeted subcortical location in the brain of the patient, and activating the plurality of magnetic assemblies at the selected locations to generate magnetic fluxes of a selected strength, frequency and duration directed into the brain of the patient, wherein the magnetic flux directed into the brain of the patient from each of the assemblies is operative to generate induced electric field in regions of the brain and the regions of induced electric fields generated by each of the plurality of magnetic assemblies converge in the targeted subcortical location and combine to a magnitude sufficient to affect the biological, cellular or biochemical function or structure in the targeted subcortical location.
US11052259B2
A connector assembly for an implantable device includes a feedthrough interface having a ceramic feedthrough and a ferrule attached to, and forming a perimeter around, the ceramic feedthrough; a lower contact housing coupled to the feedthrough interface, where the lower contact housing and ceramic feedthrough define wire holes extending therethrough; an upper contact housing attached to the lower contact housing and collectively defining contact receptacles, each of the contact receptacles defining an opening for at least one of the wire holes; connector contacts with each connector contact disposed in a one of the contact receptacles; and wires with each of the wires coupled to one of the connector contacts and extending through one of the wire holes so that the respective wire extends out of the ceramic feedthrough.
US11052256B2
An implantable medical device (IMD) includes a heterogeneous housing configured to receive and store one or more components of the IMD. The housing includes an intrinsically non-conductive and non-magnetic base material and at least one dopant with a property of at least one of electrical conductance and magnetic permeability. The base material and the dopant form a first region of the housing including a first skin depth and a second region of the housing including a second skin depth different than the first skin depth.
US11052255B2
Systems and methods for pacing cardiac conductive tissue are described. A medical system includes an electrostimulation circuit to generate His-bundle pacing (HBP) pulses. A sensing circuit senses a physiologic signal, and detect a local His-bundle activation discrete from a pacing artifact of the HBP pulse. A control circuit verifies capture status in response to the HBP pulses. Based on the capture status, the control circuit determines one or more pacing thresholds including a selective HBP threshold representing a threshold strength to capture only the His bundle but not the local myocardium, and a non-selective HBP threshold representing a threshold strength to capture both the His bundle and the local myocardium. The electrostimulation circuit may deliver HBP pulses based on the selective and non-selective HBP thresholds.
US11052252B1
Described is a system for weakening an undesirable memory. The system initiates application of a first pattern of spatiotemporally distributed transcranial stimulation via a set of electrodes to a subject who is in a calm mental state, causing association of the first pattern of spatiotemporally distributed transcranial stimulation with the calm mental state. The system then initiates application of the first pattern of spatiotemporally distributed transcranial stimulation via the set of electrodes when the undesirable memory is recalled by the subject, causing recall of the calm mental state and reconsolidation of the undesirable memory with the calm mental state.
US11052246B2
A method, system, and device for electroporation. A system may include a medical device with a plurality of electrodes borne on an expandable element and an energy generator in communication with the electrodes. The energy generator may have processing circuitry configured to selectively deliver electroporation energy to at least one of the electrodes. The processing circuitry may determine whether an alert condition is present and, if so, cease the delivery of electroporation energy to one or more electrodes identified as the cause of the alert condition and/or prevent the delivery of electroporation energy to the one or more electrodes identified as the cause of the alert condition. The energy generator may also be configured to deliver electroporation energy in a sequence of a plurality of energy delivery patterns to enhance lesion formation.
US11052243B2
A method of laparoscopically implanting an electrically stimulating lead proximate the lower esophageal sphincter (LES) of a patient includes delivering the lead through a port of a laparoscope inserted into the abdominal cavity of the patient through an incision in the abdominal wall. The stimulating electrode is implanted in or proximate the muscularis layer of the lower esophageal wall to treat esophageal reflux disease (GERD). The lead includes a needle and suture at its distal end for pulling the electrode into the muscular wall of the LES. Clips are applied to the suture attached to the distal end of the lead to prevent retrograde movement of the electrode. The lead also includes an anchoring member for anchoring the portion of the lead proximal to the electrode. The method and lead used with the method allow the surgeon to work within the confined anatomy present at the gastroesophageal junction and prevents backwards movement and dislodgment of the electrode. The implantation procedure can be combined with a hiatal hernia repair to repair the hernia and prevent recurrence of a hiatal hernia.
US11052240B2
A medical device for administering a medicament is disclosed that includes a reservoir for storing the medicament, a current driver electrically coupled to an electrode, and an oscillation driver electrically coupled to a vibrational element. The electrode forms multiple channels in fluid communication with the reservoir. A method of administering a medicament is also provided.
US11052239B2
A cannula for relieving the left side of the heart is provided, the cannula having a cannula shaft comprising a heart-side inlet and a pump-side outlet. A lumen extends between the inlet and the outlet, and a suture ring for connecting the cannula to a left atrium is arranged on an outer side of the cannula shaft. The outlet is configured such that the outlet can be connected to a pump and the length of the cannula shaft between the suture ring and the outlet is such that the cannula shaft can be guided outwards through an intercostal space.
US11052232B2
A needle assembly for a liquid applicator comprises housing with longitudinal channel. The channel comprises upper and lower open ends. A needle bundle is movably mounted in the channel, which comprises needle shaft and needles attached thereto. A biasing member is configured and mounted for (i) biasing the needle bundle longitudinally towards a retracted position and (ii) biasing the needles laterally towards a needle-guiding side wall of the housing adjacent the lower open end. The biasing member is configured and mounted to form a fluid seal between the lower and upper open ends. The biasing member comprises an elastic tubular section with opposite sides. The first side has a first rectified length. The second side has a second rectified length longer than the first rectified length so that the second side is less tensioned than the first side to bias the needles towards the needle-guiding side wall.
US11052226B2
Steerable medical devices and methods of use. In some embodiments, the steerable medical devices can be steered bi-directionally. In some embodiments the steerable medical devices include a first flexible tubular member and a second flexible tubular member secured together at a location distal to a steerable portion of the steerable medical device.
US11052225B2
There is provided an apparatus for use in a bodily lumen. The apparatus comprises a guidewire and a catheter. The guidewire has a proximal end portion and a distal end portion. The catheter has a proximal end portion and a distal end portion. The catheter includes a lumen for receiving the guidewire. The catheter is configured to be translated along the guidewire. The catheter is configured to be biased towards a translated position along the guidewire by a magnetic attraction between the guidewire and the catheter.
US11052220B2
The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative of a rate at which sleep of the subject deepens during the sleep session. The deepening time is determined based on (i) a ratio of power in a high frequency band of an EEG signal to power in a low frequency band, (ii) a density of slow waves, or (iii) a hypnogram, indicative of sleep depth in the subject during the sleep session. The system is configured to determine a rate of volume increase for auditory stimulation during a subsequent sleep session based on the deepening time; and control the one or more sensory stimulators to adjust the volume of auditory stimulation provided to the subject during the subsequent sleep session based on the determined rate of volume increase.
US11052219B2
A sensory activity sack provides a garment with pleasant tactile features offering safe sensory stimulation for persons with developmental or sensory disabilities and an isolation bag for the wearer's arms and hands. The isolation bag prevents the wearer from engaging in self-injurious behavior or other harmful behaviors. Multiple fabrics and textures in the isolation bag, including mesh and denim, provide a pleasing tactile experience, which can be furthered by the placement of toys into the isolation bag. Sensory panels made with a sturdy, textured material such as denim provide tactile stimulation and resistance against wear and biting, as well as adding a comforting weight to the sensory activity sack for wearers with sensory issues.
US11052215B2
A medical tube has a tube wall, a first end and a second end. At least one heater wire is wrapped around the wall. Near or at one of the first end or the second end, there is at least one recess in an outer surface of the wall. The heater wire passes over the at least one tube recess such that the wire does not contact the wall in the area of the tube recess. Also disclosed are methods of making the tube and components used in making the tube.
US11052202B2
Drug delivery devices that include a microphone and processing circuitry that can detect operating events, such as peak inspiratory flow (PIF) and Breath Actuated Mechanism (BAM) in dry powder inhalers can be used to improve clinical trials by providing information about the way in which the inhalers under test are being used.
US11052196B1
A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 μg/mL. The method further includes providing, on the injector, a plurality of indicia only at prescribed doses of 50 μg, 100 μg, 150 μg and 200 μg settable via the dose setter without indicia between said prescribed doses; and permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter, wherein the injector is configured to provide at least one audible feedback during the rotation.
US11052190B2
Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.
US11052187B2
A packaging for a reel of medical injection devices includes a base tray configured for supporting the reel and at least a first flat rib and a second flat rib. Each rib includes a respective slot arranged such that the ribs can be interlocked with one another by mutual engagement of the slots. The base tray includes at least two pairs of peripheral openings. Each opening is configured to receive an end of the ribs, so that the base tray and interlocked flat ribs engaging the base tray form a frame configured for enclosing the reel.
US11052184B2
A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the spinning membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib or ridge associated with the spinning membrane that decreases the gap between the spinning membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously-collected whole blood into selected blood components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
US11052182B2
The present invention relates to a method for checking a dialyzer for the presence of a leak in the semipermeable membrane of the dialyzer, wherein the membrane divides the inner dialyzer space into a least one blood chamber and into at least one dialyzate chamber, wherein the blood chamber is flowed through by blood in the operation of the dialyzer and is in fluid communication with a blood-side line system and the vascular system of the patient, and wherein the dialyzate chamber is flowed through by dialysis fluid in the operation of the dialyzer and is in fluid communication with a dialyzate-side line system, wherein the method comprises the following steps: a) emptying the blood chamber or the dialyzate chamber of blood and of dialysis fluid respectively and keeping the fluid (blood or dialyzate) in the non-emptied dialyzate chamber or blood chamber; b) building up a test pressure by means of a gas, in particular by means of air, in the emptied blood chamber or in the emptied dialyzate chamber; and c) measuring the pressure drop over time in the emptied blood chamber or in the emptied dialyzate chamber or in the line system respectively in fluid communication therewith and/or measuring the pressure increase in the non-emptied blood chamber or in the non-emptied dialyzate chamber or in the line system respectively in fluid communication therewith or measuring the number of air bubbles or of a parameter correlated with the number of air bubbles in the non-emptied blood chamber or in the non-emptied dialyzate chamber or in a line system respectively in fluid communication therewith, wherein the steps a) to c) are carried out subsequent to the blood treatment of the patient and subsequent to the disconnection of the patient from the blood-side line system.
US11052181B2
A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
US11052180B2
A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.
US11052173B2
The present disclosure relates to a biocompatible, electrically conductive polymer capable of carrying the electrical potential of a cardiac impulse. The present disclosure also relates to treatments using the electrically conductive polymer, such as for atrial fibrillation.
US11052168B2
An air germicidal treatment device and system for removing or eliminating unwanted pathogens or bacteria in an airstream is shown. The device or system has a removable irradiation chamber that divides an interior area of the device into an air pre-chamber area, an air post-chamber area and an irradiation area therebetween. The removable irradiation chamber is generally trapezoidal in shape and has end walls that are inclined with respect to an interior divider wall.
US11052163B2
The present disclosure provides peptide constructs for diagnostic imaging and therapeutic applications, using pegylated peptides which exhibit specific binding for a target molecule of interest, such as a biomarker of a disease or disorder.
US11052155B2
This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
US11052153B2
Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide increased water solubility and/or increased rate of dissolution for the solute compound. The compositions can also provide increased stability for the solute compound. Methods for preparing and using compositions including a solute compound and a highly branched alpha-D-glucan are also described.
US11052145B2
Disclosed are novel immunogenic proteins derived from Staphylococcus aureus, as well as methods for their use in conferring protective immunity against S. aureus infections. Also disclosed are nucleic acids encoding the proteins and methods of use of these nucleic acids.
US11052142B2
For the first time individual (free from impurities of penta- and hexa-acetylated derivatives) di-, tri- and tetra-acetylated S-LPS of endotoxic bacteria and combinations thereof were obtained and their immunobiological, physical-chemical and chemical-pharmaceutical properties were studied.
For the first time the principal possibility of their clinical application was directly demonstrated as vaccines and pharmaceutical compositions containing the modified S-LPS individual as monocomponent or combinations thereof as two and three component active substance, respectively.
The modified S-LPS and combinations thereof have high safety profile and provide low pyrogenicity and high immunogenicity. Developed on their basis vaccines and pharmaceutical compositions demonstrate anti-shock activity, high efficiency and specificity, broad-spectrum action and also good chemical-pharmaceutical parameters.
US11052141B1
Methods of mitigating the risk of rejection of an allograft or xenograft in an incompatible recipient by neutralizing one or more populations of circulating antibody cross-reactive with a carbohydrate antigen expressed by the allograft or xenograft. The method includes administering to the recipient by intravenous infusion a concentration of a synthetic antigen lipid construct sufficient to neutralize the one or more populations of circulating antibody in the recipient.
US11052137B2
The application relates to antimicrobial agents against Gram-negative bacteria, in particular to fusion proteins composed of an enzyme having the activity of degrading the cell wall of Gram-negative bacteria and a peptide stretch fused to the enzyme at the N- or C-terminus, as well as pharmaceutical compositions comprising the same. Moreover, it relates to nucleic acid molecules encoding such a fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, it relates to such a fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-negative bacterial infections, as diagnostic means or as cosmetic substance. The application also relates to the treatment or prevention of Gram-negative bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries.
US11052131B2
Disclosed are methods and pharmaceutical compositions for the treatment of kidney cancer. The inventors showed that while Elabela (ELA) is mostly expressed in kidney, its expression is reduced in human kidney cancer. In a xenograft animal model (sub-cutaneous, or sub-capsular injection) Ela inhibits tumor progression. In particular, there is disclosed a method of treating kidney cancer in a subject in need thereof including administering to the subject a therapeutically effective amount of an ELA polypeptide including an amino acid sequence having at least 90% of identity with SEQ ID NO: 1 (QRPVNLTMRRKLRKHNCLQRRCMPLHSRVPFP) wherein the arginine residue (R) at position 9, 10, 20 or 21 is optionally mutated.
US11052129B2
The present invention relates to methods of treating or preventing a complement-mediated disease and/or disorder in a subject with a complement C5 polymorphism, including administering to a subject in need thereof a therapeutically or prophylactically effective amount of an agent that a) inhibits the classical complement pathway, the alternative complement pathway and the lectin complement pathway; and/or b) inhibits eicosanoid activity. The invention also relates to methods of identifying patient populations with C5 polymorphisms that are treatable with specific agents that a) inhibit the classical complement pathway, the alternative complement pathway and the lectin complement pathway; and/or b) inhibit eicosanoid activity.
US11052125B2
The present invention discloses a composition comprising extracts of Cyperus rotundus, standardized to contain 3-5% w/w total stilbenes, extracts of Garcinia sp., standardized to contain 20% w/w garcinol and extracts of Coleus forskohlii standardized to contain not less than 10% w/w forskolin for the therapeutic management of diet induced obesity and weight gain and related conditions like liver dysfunction, NASH, NAFLD, liver cirrhosis, hypercholesterolemia, hyperlipidemia, kidney dysfunction by bringing about a reduction in body weight, increasing lean body mass and by normalizing the levels of liver enzymes, kidney markers and circulating lipids.
US11052119B2
The present invention relates to a cell-based composition comprising a suspension of mesenchymal stem cells in crystalloid with a cellular concentration from 0.01 million to 3.0 million cells/ml. The cell-based composition is used in a form of medicament for treatment of diabetes and its associated metabolic disorders and complications.
US11052118B2
The invention provides improved methods for cell therapy. In particular, the invention provides therapeutic compositions of enhanced hematopoietic stem and progenitor cells having improved engraftment and homing properties, and methods of making the therapeutic compositions. The invention further provides methods of improving the efficacy of hematopoietic stem and progenitor cell transplantation including transplanting the therapeutic composition to subjects in need of hematopoietic system reconstitution.
US11052114B2
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11052102B2
The present invention provides novel compounds that target thrombocyte activity or aggregation capacity through cellular components for the treatment of diseases associated with Non-Alcoholic Fatty Liver Disease (NAFLD). The invention provides these compounds for treating non-alcoholic steatohepatitis (NASH), a progressed stage of NAFL (non-alcoholic fatty liver), in order to avoid the development of liver cirrhosis and Hepatocellular Carcinoma (HCC). Further provided are pharmaceutical compositions, comprising the compounds of the invention, and methods for screening new NASH therapeuticals.
US11052100B2
A nicotinamide riboside composition and preparation method thereof, the icotinamide riboside composition comprises nicotinamide riboside and/or a salt thereof and konjac glucomannan or rebaudioside A. The nicotinamide riboside composition provided by the present invention, used to increase the concentration of NAD in cells, thereby preventing and improving various unhealthy conditions caused by NAD deficiency. is stable in property and easy to store and transport.
US11052094B2
Provided herein is an ophthalmic composition formulated in deuterated water. Also disclosed herein are methods of treating, ameliorating, or reducing ophthalmic conditions or diseases by administering to an eye of an individual in need thereof an effective amount of an ophthalmic composition as described herein.
US11052092B2
The present invention provides e.g. N-{[2-(piperidin-1-yl)phenyl](phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating e.g. autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases or cholestatic diseases, such as e.g. arthitis and asthma.
US11052089B2
In alternative embodiments, provided are compositions and methods for treating, enhancing the drug sensitivity of, and preventing the formation of cancer stems cells, including preventing or slowing the development or generation of a beta-3 (β3)-expressing, or integrin β3 (ITG-B3)-expressing cancer or tumor cells. In alternative embodiments, provided are methods using histone acetyl transferase inhibitors and/or histone methyl transferase inhibitors to determine therapeutic values in cancer cells that induce an integrin β3 (ITGB3) polypeptide expression. In alternative embodiments, provided are kits, blister packages, lidded blisters or a blister card or packet, clamshells, trays or shrink wraps, comprising at least one compound, composition or formulation used to practice a method as provided herein, and at least one Growth Factor Inhibitor.
US11052081B2
The present invention relates to therapeutic ADCs comprising SN-38 attached to an anti-Trop-2 antibody or antigen-binding antibody fragment. The ADC may be administered at a dosage of between 4 mg/kg and 18 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg, most preferably 8 to 10 mg/kg. When administered at specified dosages and schedules, the ADC can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Preferably, the ADC is administered in combination with one or more other therapeutic agents, such as a PARP inhibitor, a microtubule inhibitor, a Bruton kinase inhibitor or a PI3K inhibitor. Most preferably, the ADC is of use for treating a Trop-2 expressing cancer, such as metastatic urothelial cancer.
US11052080B2
The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer.
US11052078B2
Provided herein are compounds, derivatives thereof, composition comprising one or more of said compounds and derivatives, and methods for prevention and/or treatment of microbial infections and/or related diseases or conditions. The present compounds and/or derivatives thereof can be represented by Formula (II): The present methods include administering to a subject an effective amount of one or more compounds of Formula (II). In one embodiment, said microbial infections are bacterial infections. More specifically, said bacterial infections are staphylococcal infections.
US11052068B2
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided. Also provided are methods of treating cancer in a subject, comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. Also provided are methods of reducing cell proliferation in a subject comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof.
US11052053B2
A nanoparticle includes a core. The core includes a bio-resorbable polyester and a hydrophilic polymer. The hydrophilic polymer is a portion of the bio-resorbable polyester or a separate polymer. An acylated human lactoferrin-derived peptide is coated onto the core. The acylated human lactoferrin-derived peptide is a peptide with the amino acid sequence SEQ ID NO. 1: KCFQWQRNMRKVRGPPVSCIKR or an amino acid sequence, which does not differ by more than 8 amino acid positions from the sequence SEQ ID NO: 1. The N-terminus of the human lactoferrin-derived peptide is acylated with a C16-monoacyl group.
US11052039B2
Provided is a cosmetic composition for skin moisturization containing a hydrolyzate extract obtained by adding a protease to the fruit of Cicer arietinum, a Rhododendron chrysanthum leaf extract and a Tricholoma matsutake extract. The cosmetic composition exhibits excellent effects on cell moisturization, intercellular moisturization and skin-barrier moisturization. In addition, the cosmetic composition is harmless to the human body and has excellent stability because it uses natural substances.
US11052038B2
Disclosed are a green environmental facial cleansing tissue with a natural plant origin and its preparation method, particularly a green facial cleansing tissue with a makeup removal function and a natural plant origin formula and its preparation method. The formula of the facial cleansing tissue consists of natural plants, honey extracts, etc., and the facial cleansing tissue is capable of avoiding skin irritation, providing a convenient and safe use, and the facial cleansing tissue is naturally decomposable and environmentally friendly.
US11052035B2
Method for treating hair comprising the successive application onto hair of polymeric layers which can be removed to a large extent or even totally in an easy manner upon request of the user by using a composition having a pH less than 7.
US11052032B2
Compositions and methods for amelioration of skin laxity and body contour are provided. Provided herein are compositions comprising a combination of peptides.
US11052031B2
An aqueous cleansing composition comprising a cationic surfactant, a nonionic surfactant, and a thickener comprising an alkoxylated methyl glucose ether, wherein a weight ratio of cationic surfactant to nonionic surfactant is greater than 0.9:1. The combination of the cationionic:nonionic surfactant ratio with the alkoxylated methyl glucose ether thickener provides the composition with cold weather stability. Cold weather stability is observed when the composition remains transparent after cold storage.
US11052030B2
A method of preparing a fine oil-in-water emulsion comprising an oil phase based on silicone and/or hydrocarbon oils, in which the oil phase particles have an average particle size of 150 nm or less. The emulsion is stabilized by a carboxy-modified silicone in combination with a C16 to 22 higher alcohol; a nonionic surfactant having a POE chain and an HLB of 5 to 10; and a dihydric glycol. The emulsions can be prepared without the use of a high-pressure emulsifying apparatus.
US11052011B2
A standing-up assistance apparatus includes a first sensor that measures a muscle potential of a lower leg of a user, a second sensor that measures a knee angle of the user, a processor that determines whether starting to assist the user in a standing-up motion from a seated state is possible, based on, at least, the measured muscle potential and the measured knee angle, and outputs an instruction signal if the processor determines that starting to assist the user in the standing-up motion is possible, and an assistance mechanism. The assistance mechanism starts assisting the user in the standing-up motion when the assistance mechanism receives the instruction signal from the processor.
US11052001B2
A mobile chair apparatus is described that comprises a drive assembly that preferably includes one or more moveable foot pedals, and drive wheels which rotate in response to rotation of the foot pedals by the mobile chair occupant, and a steering assembly which comprises two steering wheels and at least one tiller, configured such that forward and backward movement of said tiller will translate into movement of both steering wheels, wherein the drive assembly and the steering assembly concurrently enable the mobile chair occupant to propel and steer the mobile chair apparatus without assistance from another person.
US11051999B2
Patient support apparatuses, such as beds, cots, stretchers, recliners, or the like, include control systems with one or more image, radar, and/or laser sensors to detect objects and determine if a likelihood of collision exists. If so, the control system controls the speed and steering of the patient support apparatus in order to reduce the likelihood of collision. The control system may be adapted to autonomously drive the patient support apparatus, to transmit a message to a remote device indicating whether it is occupied by a patient or not, and/or to transmit its route to the remote device. The remote device may determine an estimate of a time of arrival of the patient support apparatus at a particular destination and/or determine a distance of the patient support apparatus from the particular destination.
US11051998B2
A reconfigurable portable load bearing structure which can be configured into an extended load bearing configuration or a collapsed configuration, comprising of a first, second and third plurality of rail segments that are each rotatably coupled together and a plurality of support segments or pads which are configured to selectively couple and latch into one of a plurality of positions on said first, second and third plurality of rail segments.
US11051997B2
A disposable pant-type absorbent article, such as a pant diaper, a sanitary pant or incontinence pant is described. The disposable pant-type absorbent article has a longitudinal direction (Y) and a transverse direction (X). The disposable pant-type absorbent article is adapted for a male user. A method for manufacturing such a disposable pant-type absorbent article is also described.
US11051984B2
A ventilation unit and controller device comprises a ventilation unit with a housing. The housing has an intake port permitting flow of gas into the housing and an exhaust port permitting flow of gas out of the housing. Within the housing, a motorized fan is positioned to direct gas into the housing via the intake port and out of the housing via the exhaust port. A controller capable of controlling the ventilation unit communicates with a sensor capable of detecting an environmental stimulus. A source of electric current provides power to the ventilation unit and controller device. The device further comprises a switch capable of interrupting the electric current that powers the device. The device is capable of being removably attached via fasteners to an arc flash hood, and the arc flash hood comprises a ventilation opening to permit gas discharged by the device to enter the arc flash hood.
US11051982B2
A plug for occluding an ocular canaliculus comprises a cylindrical body member having a first outer diameter. The cylindrical body member is provided along an external surface with at least one outwardly extending projection having a second outer diameter greater than the first outer diameter and larger than an inner diameter of an ocular canaliculus. The first outer diameter of the plug is typically less than and approximately equal to the inner diameter of the canaliculus.
US11051981B2
Devices, systems, and methods for performing an ophthalmic procedure in an eye are disclosed. The devices include a hand-held portion and a distal, elongate member coupled to the hand-held portion having a lumen operatively coupled to a vacuum source. A drive mechanism operatively coupled to the elongate member is configured to oscillate the elongate member. When in use, the device is configured to aspirate ocular material from the eye through the lumen. The drive mechanism retracts the elongate member with a retraction speed profile and advances the elongate member with an extension speed profile. The retraction speed profile is different from the extension speed profile.
US11051977B2
An eye treatment apparatus is described. The apparatus includes an annular body that has a hollow optical zone in its center. An inner perimeter of the annular body surrounds the optical zone. The inner perimeter has a diameter that corresponds to a diameter of the eye's cornea. An outer perimeter of the annular body has a diameter such that the annular body can extend to underneath the eye lid in an open eye position when the eye treatment apparatus is in operation. In this way, the apparatus can be worn on the eye, where the hollow optical zone substantially corresponds to the cornea and does not interfere with the field of vision. The annular body also includes a storage chamber that stores therapeutic liquid for an eye. An outlet is coupled with the storage chamber such that, in operation, the therapeutic liquid can be dispensed to the eye.
US11051970B2
A single use device for capturing fecal matter excreted from the anus of a user. The device includes a flexible fecal matter container having a closed end and an opening that is in fluid communication with a volume enclosed by the flexible container. An adhesive is disposed about the opening of the flexible container and has a first side that is secured to the flexible container. A second side of the adhesive is constructed to be removably applied to the epidermis of the user proximate an anal opening of the user. The adhesive is shaped to cooperate with the epidermis to circumscribe the anus in a sealed manner without interfering or overlapping anatomy associated with urinary function or medical devices, such as a catheter, associated therewith.
US11051969B2
An adaptable ostomy base plate comprising a flexible top film, having a first section and a second section, and having at least a first elastic skin-friendly adhesive on a proximal surface of said flexible top film, a stoma-receiving through-going hole defining an inner boundary in said first section, said first section being adjacent to and extending radially from said through-going hole and said second section surrounding said first section defining an outer boundary of the base plate, and one or more release liners, the base plate has a substantially convex shape for initial engagement with a peristomal skin surface and can be inverted to a substantially concave shape to fittingly engage to a topography of the peristomal skin surface and the second section of the base plate is in the form of a plurality of petals extending away from the central area; and a plurality of bridges, each bridge formed between adjacent petals of the plurality of petals.
US11051964B1
A posture supportive garment for supporting for a user's chest, back, and shoulders, while simultaneously reinforcing body alignment in the thoracic region to improve posture may include a bra structure having right and left cups sized to accommodate a user's breasts; a support base sized to encircle a user's torso, the support base attached to a bottom portion of the right and left cups; and right and left shoulder straps ultimately attached to the right and left cups, respectively, and the support base, wherein each of the right and left cups includes a compression sling; each of the right and left shoulder straps includes a lined compression panel; and the support base is made of a compression material.
US11051960B2
There is disclosed a control system for controlling the inflation of a balloon in a balloon stent catheter arrangement including (i) a transducer adapted to receive a source of intracoronary arterial pressure in a patient's coronary artery and to provide arterial pressure waveform data indicative of the status of a patient's cardiac cycle based upon the intracoronary arterial pressure, (ii) a processing system adapted to process the arterial pressure waveform data, and (iii) an inflation pump adapted to inflate the balloon. The processing system is adapted to cause the inflation pump to inflate the balloon in diastole, corresponding to about 55% to about 85% of a single R-R interval of the cardiac cycle, by an amount sufficient to achieve fixation of the stent at a target site in the coronary artery.
US11051957B2
Systems, devices and methods for control of a prosthetic or orthotic device (POD) based on electromyography (EMG) signals are described. The POD may be a lower or upper limb POD having one or more joints. One or more EMG sensors may detect the EMG signals. The EMG sensors may be external, subcutaneous, intraperitoneal, epimysial, intramuscular, or other types. Control of the POD may be based on EMG and non-EMG signals, such as velocity, acceleration, position, force, etc. Voluntary and/or automatic control may be implemented, for example with voluntary muscle contractions and/or data based on velocity, acceleration, position, force, etc. In some embodiments, the neutral position of an ankle POD is adjusted based on EMG signals.
US11051956B2
A prosthesis cosmetic element for a prosthesis comprising a prosthesis joint which has an upper part and a lower part that is mounted thereon in a pivotal manner about a pivot axis, the prosthesis cosmetic element has a first frame part, which has at least one first securing device for fixing on the lower part, and a second frame part with at least one second securing device for securing on the upper part. The frame parts are mounted in a pivotal manner relative to each other, and the prosthesis joint is equipped with a rotational element on which an actuating element is arranged. The actuating element is accessible from the outside by a frame part or through a frame part.
US11051954B2
An expandable support device for tissue repair is disclosed. The device can be used to repair hard or soft tissue, such as bone or vertebral discs. A method of repairing tissue is also disclosed. The device and method can be used to treat compression fractures. The compression fractures can be in the spine. The device can be deployed by compressing the device longitudinally resulting in radial expansion.
US11051951B2
An expandable inter-body fusion device is presented. The expandable inter-body fusion device can have a first plate, a second plate, and an insert positioned substantially therebetween the first plate and the second plate. The first plate, the second plate, and the insert define an interior cavity. Moving the insert longitudinally with respect to the first and second plates increases or decreases the distance of the first plate with respect to the second plate, effectively expanding the inter-body fusion device and increasing the volume of the interior cavity.